{"id":12899,"date":"2017-01-18T07:13:19","date_gmt":"2017-01-17T23:13:19","guid":{"rendered":"\/\/www.gsbet888.com\/?p=12899"},"modified":"2020-05-04T12:05:40","modified_gmt":"2020-05-04T04:05:40","slug":"%e5%bc%a0%e7%bb%aa%e7%a9%86","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/chemists\/2017\/01\/%e5%bc%a0%e7%bb%aa%e7%a9%86.html","title":{"rendered":"\u5f20\u7eea\u7a46 Xumu Zhang"},"content":{"rendered":"<p>\u5f20\u7eea\u7a46\uff081961\u5e74-\uff09\uff0c\u4e2d\u56fd\u8457\u540d\u5316\u5b66\u5bb6\uff0c\u7f8e\u8d44<a href=\"http:\/\/salesm.company.lookchem.cn\">\u51ef\u745e\u65af\u5fb7\u751f\u5316\u6709\u9650\u516c\u53f8<\/a>(Chiral Quest Inc)\u7684\u521b\u59cb\u4eba\u3001\u6267\u884c\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u79d1\u5b66\u5bb6\u3002\u73b0\u4efb\u5357\u65b9\u79d1\u6280\u5927\u5b66\u5316\u5b66\u7cfb\u8bb2\u5ea7\u6559\u6388\uff0c\u7cfb\u4e3b\u4efb\u3002<\/p>\n<p>&nbsp;<\/p>\n<h4><strong>\u7ecf\u5386<\/strong><\/h4>\n<ul>\n<li>1982\u5e74\u6b66\u6c49\u5927\u5b66\u83b7\u5f97\u5b66\u58eb\u5b66\u4f4d<\/li>\n<li>1985\u5e74\u4e2d\u56fd\u79d1\u5b66\u9662\u798f\u5efa\u7269\u8d28\u7ed3\u6784\u7814\u7a76\u6240\u83b7\u5f97\u7855\u58eb\u5b66\u4f4d\uff0c\u5e08\u4ece\u5362\u5609\u9521\u9662\u58eb\uff08\u8bfa\u8d1d\u5c14\u83b7\u5956\u8005Linus Pauling \u7684\u535a\u58eb\u540e\uff0c\u65f6\u4efb\u4e2d\u56fd\u79d1\u5b66\u9662\u9662\u957f\uff09<\/li>\n<li>1987\u5e74\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\uff08University of California, San Diego\uff09\u83b7\u5f97\u7855\u58eb\u5b66\u4f4d\uff0c\u5e08\u4eceGerhard N. Schauzer\u6559\u6388<\/li>\n<li>1992\u5e74\u65af\u5766\u798f\u5927\u5b66\uff08Stanford University\uff09\u83b7\u5f97\u535a\u58eb\u5b66\u4f4d\uff0c\u5e08\u4ece\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u9662\u58ebJames P. Collman\u6559\u6388\uff08\u4e24\u4f4d\u8bfa\u8d1d\u5c14\u83b7\u5956\u8005Sharpless\u548cGrubbs\u7684\u5bfc\u5e08\uff09<\/li>\n<li>1992\u20141994\u5e74\u65af\u5766\u798f\u5927\u5b66\u505a\u535a\u58eb\u540e\u7814\u7a76<\/li>\n<li>1994\u20142006\u5e74\u4efb\u6559\u4e8e\u7f8e\u56fd\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5dde\u5dde\u7acb\u5927\u5b66\uff08Penn State University\uff09\u5e76\u83b7\u7ec8\u8eab\u6559\u6388\u804c\u4f4d<\/li>\n<li>2000\u5e74\u521b\u7acb\u51ef\u745e\u65af\u5fb7\u751f\u5316\u6709\u9650\u516c\u53f8\uff08Chiral Quest\uff09<\/li>\n<li>2007\u20142015\u5e74\u4efb\u65b0\u6cfd\u897f\u5dde\u7acb\u5927\u5b66\u5316\u5b66\u5b66\u9662\u6770\u51fa\u8bb2\u5e2d\u6559\u6388<\/li>\n<li>2005\u5e74\u53d7\u8058\u6b66\u6c49\u5927\u5b66 \u521b\u5efa\u7eff\u8272\u50ac\u5316\u7814\u7a76\u6240<\/li>\n<li>2008\u5e74\u53d7\u8058\u6b66\u6c49\u5927\u5b66\u201c\u9ad8\u7b49\u5b66\u6821\u5b66\u79d1\u521b\u65b0\u5f15\u667a\u8ba1\u5212\u201d\u5b66\u672f\u5927\u5e08<\/li>\n<li>2015\u5e74\u8d77\u4efb\u5357\u65b9\u79d1\u6280\u5927\u5b66\u5316\u5b66\u7cfb\u7cfb\u4e3b\u4efb\uff0c\u6559\u6388<\/li>\n<\/ul>\n<p><!--more--><\/p>\n<p>&nbsp;<\/p>\n<h4><strong>\u83b7\u5956\u7ecf\u5386<\/strong><\/h4>\n<ul>\n<li>1991\u5e74Franklin Veatch Graduate Fellowship\uff0cStanford University<\/li>\n<li>1994\u5e74The Camille and Henry Dreyfus Foundation New Faculty Award<\/li>\n<li>1996\u5e74DuPont Young Faculty Award<\/li>\n<li>1996\u5e74Office of Naval Research Young Investigator Award<\/li>\n<li>1998\u5e74The Camille and Henry Dreyfus Foundation Teacher-Scholar Award<\/li>\n<li>2000\u5e74The John Simon Guggenheim Foundation Fellow<\/li>\n<li>2000\u5e74The Outstanding Oversea Chinese Young Scientist B, Chinese Academy of Sciences<\/li>\n<li>2001\u5e74The Penn State Faculty Scholar Medal<\/li>\n<li>2002\u5e74The American Chemical Society Arthur C. Cope Scholar Award<\/li>\n<li>2002\u5e74The SDCA (San Diego Chinese Association) Achievement Award<\/li>\n<li>2008\u5e74\u82cf\u5dde\u5de5\u4e1a\u56ed\u533a\u7b2c\u4e8c\u5c4a\u79d1\u6280\u9886\u519b\u4eba\u624d<\/li>\n<li>2008\u5e74\u201c\u6c5f\u82cf\u7701\u9ad8\u5c42\u6b21\u521b\u65b0\u521b\u4e1a\u4eba\u624d\u5f15\u8fdb\u8ba1\u5212\u201d\u5f15\u8fdb\u4eba\u624d<\/li>\n<li>2009\u5e74\u59d1\u82cf\u521b\u65b0\u521b\u4e1a\u9886\u519b\u4eba\u624d<\/li>\n<li>2011\u5e74 2010 \u5e74\u5ea6\u201c\u4e2d\u56fd\u7ecf\u6d4e\u5341\u5927\u521b\u65b0\u4eba\u7269\u201d<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><strong>\u7814\u7a76<\/strong><\/h4>\n<p>\u81ea\u7136\u754c\u6709\u8bb8\u591a\u5206\u5b50\u6070\u5982\u4eba\u7684\u5de6\u624b\u548c\u53f3\u624b\uff0c\u7ec4\u6210\u6210\u5206\u5b8c\u5168\u76f8\u540c\uff0c\u7ed3\u6784\u4e0a\u5374\u5f62\u6210\u955c\u50cf\u5bf9\u79f0\uff0c\u8fd9\u4e00\u5c5e\u6027\u88ab\u4eba\u4eec\u5f62\u8c61\u5730\u79f0\u4e3a\u201c\u624b\u6027\u201d\u3002\u7531\u4e8e\u4e0d\u540c\u624b\u6027\u7684\u5206\u5b50\u4f1a\u4ea7\u751f\u4e0d\u540c\u751a\u81f3\u76f8\u53cd\u7684\u6027\u8d28\u548c\u4f5c\u7528\uff0c\u6240\u4ee5\u8fdb\u884c\u836f\u7269\u5408\u6210\u65f6\u5fc5\u987b\u52a0\u4ee5\u533a\u5206\u3002\u4f20\u7edf\u5de5\u827a\u533a\u5206\u624b\u6027\u5316\u5408\u7269\u4f1a\u9020\u6210\u4e00\u534a\u7684\u6d6a\u8d39\uff0c\u5f20\u7eea\u7a46\u5f00\u59cb\u601d\u7d22\uff0c\u5982\u679c\u901a\u8fc7\u624b\u6027\u50ac\u5316\u80fd\u76f4\u63a5\u751f\u4ea7\u51fa\u9700\u8981\u7684\u5de6\u65cb\u6216\u662f\u53f3\u65cb\u5316\u5408\u7269\uff0c\u90a3\u5236\u836f\u5de5\u827a\u5c31\u8981\u7cbe\u7b80\u3001\u9ad8\u6548\u5f88\u591a\u3002<\/p>\n<p>\u57fa\u4e8e\u6b64\uff0c\u5f20\u7eea\u7a46\u63d0\u51fa\u4e86\u201c\u624b\u6027\u5de5\u5177\u7bb1\u201d\u7684\u6982\u5ff5\u5e76\u5408\u6210\u4e86\u4e00\u4e9b\u6709\u5f71\u54cd\u7684\u624b\u6027\u914d\u4f53\uff0c\u4ed6\u7684\u7814\u7a76\u5c0f\u7ec4\u8fd8\u5229\u7528\u5408\u6210\u7684\u624b\u6027\u914d\u4f53\uff0c\u5bf9\u78b3\u2014\u6c27\u53cc\u952e\u3001\u78b3\u2014\u78b3\u53cc\u952e\u3001\u78b3\u2014\u6c2e\u53cc\u952e\u7684\u8fd8\u539f\u3001Michael \u52a0\u6210\u53cd\u5e94\u7b49\u8fdb\u884c\u4e86\u7814\u7a76\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/02.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-12901 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/02.png\" width=\"580\" height=\"494\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/02.png 580w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/02-300x256.png 300w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/03.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-12902 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/03.png\" width=\"580\" height=\"162\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/03.png 580w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/03-300x84.png 300w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/a><\/p>\n<p>\u6b64\u5916\uff0c\u5f20\u7eea\u7a46\u8fd8\u957f\u671f\u4ece\u4e8b\u4e8e\u94d1\u50ac\u5316\u4e0b\u7684\u70ef\u7094\u73af\u5316\u53cd\u5e94\uff0c\u5229\u7528\u5408\u6210\u7684\u624b\u6027\u914d\u4f53\uff0c\u53ef\u4ee5\u65b9\u4fbf\u7684\u5b9e\u73b0\u70ef\u70c3\u548c\u7094\u70c3\u5206\u5b50\u5185\u7684\u4e0d\u5bf9\u79f0\u73af\u5316\uff0c\u5177\u6709\u5f88\u597d\u7684\u533a\u57df\u9009\u62e9\u6027\u4ee5\u53ca\u7acb\u4f53\u9009\u62e9\u6027\uff0c\u9ad8\u6548\u5730\u6784\u7b51\u4e00\u7cfb\u5217\u4e94\u5143\u73af\u5316\u5408\u7269\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/04.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-12903 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/04.png\" width=\"435\" height=\"229\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/04.png 435w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/04-300x158.png 300w\" sizes=\"(max-width: 435px) 100vw, 435px\" \/><\/a><\/p>\n<h4><strong>\u8bc4\u8bba\uff06\u5176\u4ed6<\/strong><\/h4>\n<ul>\n<li>\u5f20\u7eea\u7a46\u4e0d\u4ec5\u662f\u8363\u83b7\u7f8e\u56fd\u5316\u5b66\u4f1aCope Scholar \u5956\u7684\u6765\u81ea\u4e2d\u56fd\u5927\u9646\u7684\u9996\u4f4d\u5b66\u8005\uff0c\u4e5f\u662f\u9996\u4f4d\u5c06\u5176\u751f\u7269\u533b\u836f\u516c\u53f8\u5e26\u8fdb\u7f8e\u56fdOTCBB\u4e0a\u5e02\u7684\u5927\u9646\u4f01\u4e1a\u5bb6\u3002\u56de\u56fd\u540e\uff0c\u4ed6\u4e00\u76f4\u81f4\u529b\u4e8e\u5c06<a href=\"http:\/\/salesm.company.lookchem.cn\">\u51ef\u745e\u65af\u5fb7\u751f\u5316\u6709\u9650\u516c\u53f8<\/a>\u6253\u9020\u6210\u4e3a\u4e2d\u56fd\u7eff\u8272\u751f\u7269\u533b\u836f\u7684\u9886\u519b\u4f01\u4e1a\u3002\u6709\u7740\u591a\u5e74\u7684\u3001\u6210\u529f\u7684\u5de5\u4e1a\u5316\u5e94\u7528\u7ecf\u9a8c\u548c\u80cc\u666f\u3002\u5982\u5728\u4e0d\u5bf9\u79f0\u6c22\u5316\u7684\u5de5\u4e1a\u5316\u5e94\u7528\u9886\u57df\u5728\u4e2d\u56fd\u4e43\u81f3\u4e16\u754c\u5904\u4e8e\u7edd\u5bf9\u9886\u5148\u7684\u5730\u4f4d\uff0c\u76f8\u5173\u7684\u91cd\u5927\u836f\u7269\u5982\u96f7\u7c73\u666e\u5229\u3001\u5ea6\u6d1b\u897f\u6c40\u548c\u897f\u4ed6\u5217\u6c40\u4e2d\u95f4\u4f53\u7684\u7eff\u8272\u5408\u6210\u65b0\u5de5\u827a\u7684\u5de5\u4e1a\u5316\u5e94\u7528\u89c4\u6a21\u5927\u3001\u6c61\u67d3\u5c0f\u3001\u6548\u76ca\u6781\u9ad8\uff0c\u5728\u77ed\u77ed\u6570\u5e74\u4e4b\u5185\u4ea7\u503c\u5df2\u8fbe\u4e00\u4ebf\u5143\u4eba\u6c11\u5e01\uff0c\u6570\u5e74\u4e4b\u540e\u5c06\u8fbe\u5230\u5341\u51e0\u4ebf\u4eba\u6c11\u5e01\u3002\u5f20\u7eea\u7a46\u5f00\u53d1\u7684\u6570\u4e2a\u91cd\u5927\u836f\u7269\u539f\u6599\u836f\u5747\u5df2\u7ecf\u6210\u529f\u83b7\u5f97\u7f8e\u56fdFDA\u8ba4\u53ef\u7684DMF\u53f7\uff08\u836f\u7269\u4e3b\u63a7\u6863\u6848\uff09\u3002<\/li>\n<li>\u957f\u671f\u4ece\u4e8b\u9ad8\u6548\u9ad8\u9009\u62e9\u6027\u7684\u50ac\u5316\u7814\u7a76\u3002\u5728Science\uff1bJ. Am. Chem. Soc.\uff1bAngew. Chem.\u7b49\u5b66\u672f\u520a\u7269\u4e0a\u53d1\u8868\u5b66\u672f\u8bba\u8457220\u4f59\u7bc7\uff0c\u8bba\u6587\u4ed6\u5f15&gt;12000\u6b21, \u5176\u4e2d\u5355\u7bc7\u8bba\u6587\u4ed6\u5f15&gt;1000\u6b21\uff0cH index &gt;65\u3002\u6b64\u5916\uff0c\u7531\u5176\u53d1\u5c55\u7684\u5f20\u70ef\u7094\u73af\u5f02\u6784\u5316\u53cd\u5e94\uff08Zhang enyne cycloisomerization\uff09\u6210\u4e3a\u4ee5\u4e2d\u56fd\u4eba\u540d\u547d\u7684\u4e3a\u6570\u4e0d\u591a\u7684\u4eba\u540d\u53cd\u5e94\u4e4b\u4e00\u3002<\/li>\n<li>\u5728\u4e16\u754c\u4e0a\uff0c\u4ed6\u6700\u5148\u63d0\u51fa\u4e86\u201c\u624b\u6027\u5de5\u5177\u7bb1\u201d\u7684\u6982\u5ff5\uff0c\u6210\u4e3a\u8363\u83b7\u7f8e\u56fd\u5316\u5b66\u4f1aCopeScholar\u5956\u7684\u6765\u81ea\u4e2d\u56fd\u5927\u9646\u7684\u9996\u4f4d\u5b66\u8005\u3002\u5728\u4e0d\u5bf9\u79f0\u6c22\u5316\u548c\u624b\u6027\u914d\u4f53\u8fd9\u4e24\u4e2a\u9886\u57df\uff0cScifinder\u641c\u7d22\u6392\u540d\u5747\u4f4d\u5c45\u4e16\u754c\u524d\u8305\u3002<\/li>\n<li>2002\u5e74\uff0c\u5728\u4e09\u540d\u79d1\u5b66\u5bb6\u51ed\u501f\u624b\u6027\u50ac\u5316\u7814\u7a76\u83b7\u5f97\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u7684\u7b2c\u4e8c\u5e74\uff0c\u5f20\u7eea\u7a46\u83b7\u5f97\u4e86\u7f8e\u56fd\u5316\u5b66\u5b66\u4f1a\u9881\u53d1\u7684\u8003\u666e\u5b66\u8005\u5956\u3002\u56fd\u9645\u540c\u884c\u9ad8\u5ea6\u8bc4\u4ef7\u4e86\u4ed6\u7684\u7814\u7a76\u6210\u679c\uff1a\u201c\u5f20\u5148\u751f\u7528\u4e8e\u4e0d\u5bf9\u79f0\u6c22\u5316\u7684\u624b\u6027\u914d\u4f53\u7814\u7a76\uff0c\u5411\u5b9e\u7528\u7684\u4e0d\u5bf9\u79f0\u50ac\u5316\u8fc8\u51fa\u4e86\u91cd\u8981\u7684\u4e00\u6b65\u3002\u4ed6\u53d1\u5c55\u7684\u7528\u4e8e\u9ad8\u5bf9\u6620\u9009\u62e9\u6027\u5730\u6c22\u5316\u8102\u80aa\u916e\u7684\u50ac\u5316\u5242\uff0c\u5728\u7b80\u5355\u916e\u7684\u4e0d\u5bf9\u79f0\u6c22\u5316\u65b9\u9762\u7684\u5f71\u54cd\u529b\uff0c\u4e0e2001\u5e74\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u83b7\u5f97\u8005<a href=\"\/\/www.gsbet888.com\/chemists\/2014\/08\/%e9%87%8e%e4%be%9d-%e8%89%af%e6%b2%bb-ryoji-noyori.html\">\u00a0\u91ce\u4f9d\u826f\u6cbb\uff08Ryouji Noyor)<\/a>\u4e0d\u76f8\u4e0a\u4e0b\u3002\u201d<\/li>\n<li>2014\u5e74\uff0c\u4ed6\u53d1\u660e\u7684\u94d1\u50ac\u5316\u4e0b\u7684\u70ef\u7094\u73af\u5316\u5f02\u6784\u5316\u53cd\u5e94\u88ab\u56fd\u9645\u5316\u5b66\u6743\u5a01\u8457\u4f5c\u300aName Reactions\u300b\u6536\u5f55\uff0c\u5e76\u88ab\u547d\u540d\u4e3a\u201cZhang enyne cycloisomerization\u201d\uff0c\u51e0\u767e\u5e74\u6765\u66fe\u83b7\u5f97\u7684\u534e\u4eba\u5b66\u8005\u4e0d\u8d85\u8fc75\u4eba\u3002<\/li>\n<\/ul>\n<h4><strong>\u76f8\u5173\u6587\u732e<\/strong><\/h4>\n<ol>\n<li>Highly Regio- and Enantioselective Synthesis of Unsaturated Amido Esters by Catalytic Hydrogenation of Conjugated Enamides. M. Gao, J. Meng, H. Lv, and X. Zhang. Angew. Chem. Int. Ed., 2015, 54, 1885 \u20131887.<strong>DOI<\/strong>: 10.1002\/anie.201410213<\/li>\n<li>Rhodium Catalyzed Asymmetric Hydrogenation of 2-Pyridine Ketones. H. Yang, N. Huo, P. Yang, H. Pei, H. Lv, and X. Zhang. Org. Lett., 2015, 17, 4144\u20134147.\u00a0<strong>DOI<\/strong>: 10.1021\/acs.orglett.5b01878<\/li>\n<li>First Iridium-Catalyzed Highly Enantioselective Hydrogenation of \u03b2-Nitroacrylates. S. Li, T. Xiao, D. Li, and X. Zhang. Org. Lett., 2015, 17, 782\u20133785.\u00a0<strong>DOI<\/strong>: 10.1021\/ol5034332<\/li>\n<li>Highly Enantioselective Hydrogenation of\u2002\u03bf-Alkoxy Tetrasubstituted Enamides Catalyzed by a Rh\/(R,S)-JosiPhos Catalyst. J. Meng, M. Gao, H. Lv, and X. Zhang. Org. Lett., 2015, 17, 1842\u20131845.<strong>DOI<\/strong>: 10.1021\/acs.orglett.5b00401<\/li>\n<li>Highly Efficient Synthesis of Chiral \u03b1-CF3\u2002Amines via Rh-Catalyzed Asymmetric Hydrogenation. J. Jiang, W. Lu, H. Lv, and X. Zhang. Org. Lett., 2015, 17, 1154\u20131156.\u00a0<strong>DOI<\/strong>: 10.1021\/acs.orglett.5b00087<\/li>\n<li>Highly Efficient Tetradentate Ruthenium Catalyst for Ester Reduction: Especially for Hydrogenation of Fatty Acid Esters. X. Tan, Y. Wang, Y. Liu, F. Wang, L. Shi, K. Lee, Z. Lin, H. Lv, and X. Zhang. Org. Lett., 2015, 17, 454\u2013457.\u00a0<strong>DOI<\/strong>: 10.1021\/ol503456j<\/li>\n<li>Rhodium-Catalyzed Enantioselective Hydrogenation of Tetrasubstituted \u03b1-Acetoxy \u03b2-Enamido Esters: A New Approach to Chiral \u03b1-Hydroxyl-\u03b2-amino Acid Derivatives. Q. Wang, W. Huang, H. Yuan, Q. Cai, L. Chen, H. Lv, and X. Zhang. J. Am. Chem. Soc., 2014, 136, 16120\u201316123.<strong>DOI<\/strong>:10.1021\/ja509005e<\/li>\n<li>Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst. M. Chang, Y. Huang, S. Liu, Y. Chen, S.W. Krska, I. W. Davies, and X. Zhang. Angew. Chem. Int. Ed., 2014, 53, 12761 \u201312764.<strong>DOI<\/strong>: 10.1002\/anie.201406762<\/li>\n<li>Rhodium-Catalyzed Asymmetric Hydrogenation of Unprotected NH Imines Assisted by a Thiourea. Q. Zhao, J. Wen, R. Tan, K. Huang, P. Metola, R. Wang, E. V. Anslyn, and X. Zhang. Angew. Chem. Int. Ed., 2014, 53, 8467 \u20138470.<strong>DO<\/strong>I: 10.1002\/anie.201404570<\/li>\n<li>T.-L. Liu, C.-J. Wang, X. Zhang*; Synthesis of Chiral Aliphatic Amines through Asymmetric Hydrogenation. Angew. Chem. Int. Ed. 2013, 52, 8416.<strong>DOI<\/strong>: 10.1002\/anie.201302943<\/li>\n<li>S. Li, K. Huang, B. Cao, J. Zhang, W. Wu, X. Zhang*; Highly Enantioselective Hydrogenation of beta, beta-Disubstituted Nitroalkenes. Angew. Chem. Int. Ed. 2012, 51, 8573.\u00a0<strong>DOI<\/strong>: 10.1002\/anie.201202715<\/li>\n<li>M. Chang, W. Li, X. Zhang*; A highly efficient and enantioselective access to tetrahydroisoquinoline alkaloids: asymmetric hydrogenation with an iridium catalyst. Angew. Chem. Int. Ed, 2011, 50, 10679.<strong>DOI<\/strong>: 10.1002\/anie.201104476<\/li>\n<li>G. Hou, W. Li, M. Ma, X. Zhang, X. Zhang*; Highly efficient Iridium-catalyzed asymmetric hydrogenation of unprotected \u03b2-Enamine esters. J. Am. Chem. Soc. 2010, 132, 12844.<strong>DOI<\/strong>: 10.1021\/ja105674y<\/li>\n<\/ol>\n<p><strong>\u5916\u90e8\u94fe\u63a5<\/strong><\/p>\n<ul>\n<li><a href=\"http:\/\/www.sustc.edu.cn\/chemistry_04\/f\/Zhang_Xumu\">\u5f20\u7eea\u7a46 \u5357\u65b9\u79d1\u6280\u5927\u5b66\u5e08\u8d44\u961f\u4f0d<\/a><\/li>\n<li><a href=\"http:\/\/www.sustc.edu.cn\/chemistry_11\/535\">\u5316\u5b66\u7cfb\u4e3b\u4efb\u5f20\u7eea\u7a46\uff1a\u4e66\u67b6\u8d27\u67b6\u90fd\u8981\u4e0a\u00a0<\/a><\/li>\n<li><a href=\"http:\/\/baike.baidu.com\/link?url=6t3ifg3TX6-A0j2fk-r7zV11JzBVA7Jvn0oVaGAYVMOf1VSqArDUZ_m7Ri2QarKf_8l2k9mOpWfhTeIacnUNpbmCRjyoe14jdktLJAAnVRkD_vgvJMGxVCsHHjTEBbKU\">\u5f20\u7eea\u7a46-\u767e\u5ea6\u767e\u79d1<\/a><\/li>\n<li><a href=\"http:\/\/blog.sina.com.cn\/s\/blog_5fca42380102wegy.html\">\u5f20\u7eea\u7a46-\u505a\u5b8c\u7f8e\u5316\u5b66\u53cd\u5e94<\/a><\/li>\n<li><a href=\"http:\/\/www.cst.sh.cn\/xwzx\/xwdt\/200203\/t20020328_2702895.html\">\u6709\u673a\u6240\u5ba2\u5ea7\u6559\u6388\u5f20\u7eea\u7a46\u8363\u83b72002\u5e74\u5ea6\u201c\u8003\u666e\u201d\u5b66\u8005\u5956<\/a><\/li>\n<li><a href=\"http:\/\/www.chinesevacuum.com\/ShowArticle.aspx?id=40800\">2013\u5170\u5dde\u5316\u7269\u6240\u6240\u5e8655\u5468\u5e74\u5b66\u672f\u62a5\u544a\u4f1a\u9884\u544a<\/a><\/li>\n<li><a href=\"http:\/\/www.x-mol.com\/news\/1441?plg_nld=1&amp;plg_uin=1&amp;plg_auth=1&amp;plg_nld=1&amp;plg_%20usr=1&amp;plg_vkey=1&amp;plg_dev=1\">\u6709\u673a\u4eba\u540d\u53cd\u5e94\u4e2d\u7684\u90a3\u4e9b\u4e2d\u56fd\u4eba<\/a><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>\u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/strong><\/p>\n<div><\/div>\n<div><\/div>\n","protected":false},"excerpt":{"rendered":"\u5f20\u7eea\u7a46\uff081961\u5e74-\uff09\uff0c\u4e2d\u56fd\u8457\u540d\u5316\u5b66\u5bb6\uff0c\u7f8e\u8d44\u51ef\u745e\u65af\u5fb7\u751f\u5316\u6709\u9650\u516c\u53f8(Chiral Quest Inc)\u7684\u521b\u59cb\u4eba\u3001\u6267\u884c\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u79d1\u5b66\u5bb6\u3002\u73b0\u4efb\u5357\u65b9\u79d1\u6280\u5927\u5b66\u5316\u5b66\u7cfb\u8bb2\u5ea7\u6559\u6388\uff0c\u7cfb\u4e3b\u4efb\u3002 &nbsp; \u7ecf\u5386 1982\u5e74\u6b66\u6c49\u5927\u5b66\u83b7\u5f97\u5b66\u58eb\u5b66\u4f4d 1985\u5e74\u4e2d\u56fd\u79d1\u5b66\u9662\u798f\u5efa\u7269\u8d28\u7ed3\u6784\u7814\u7a76\u6240\u83b7\u5f97\u7855\u58eb\u5b66\u4f4d\uff0c\u5e08\u4ece\u5362\u5609\u9521\u9662\u58eb\uff08\u8bfa\u8d1d\u5c14\u83b7\u5956\u8005Linus Pauling \u7684\u535a\u58eb\u540e\uff0c\u65f6\u4efb\u4e2d\u56fd\u79d1\u5b66\u9662\u9662\u957f\uff09 1987\u5e74\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\uff08University of California, San Diego\uff09\u83b7\u5f97\u7855\u58eb\u5b66\u4f4d\uff0c\u5e08\u4eceGerhard N. Schauzer\u6559\u6388 1992\u5e74\u65af\u5766\u798f\u5927\u5b66\uff08Stanford University\uff09\u83b7\u5f97\u535a\u58eb\u5b66\u4f4d\uff0c\u5e08\u4ece\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u9662\u58ebJames P. Collman\u6559\u6388\uff08\u4e24\u4f4d\u8bfa\u8d1d\u5c14\u83b7\u5956\u8005Sharpless\u548cGrubbs\u7684\u5bfc\u5e08\uff09 1992\u20141994\u5e74\u65af\u5766\u798f\u5927\u5b66\u505a\u535a\u58eb\u540e\u7814\u7a76 1994\u20142006\u5e74\u4efb\u6559\u4e8e\u7f8e\u56fd\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5dde\u5dde\u7acb\u5927\u5b66\uff08Penn State University\uff09\u5e76\u83b7\u7ec8\u8eab\u6559\u6388\u804c\u4f4d 2000\u5e74\u521b\u7acb\u51ef\u745e\u65af\u5fb7\u751f\u5316\u6709\u9650\u516c\u53f8\uff08Chiral Quest\uff09 2007\u20142015\u5e74\u4efb\u65b0\u6cfd\u897f\u5dde\u7acb\u5927\u5b66\u5316\u5b66\u5b66\u9662\u6770\u51fa\u8bb2\u5e2d\u6559\u6388 2005\u5e74\u53d7\u8058\u6b66\u6c49\u5927\u5b66 \u521b\u5efa\u7eff\u8272\u50ac\u5316\u7814\u7a76\u6240 2008\u5e74\u53d7\u8058\u6b66\u6c49\u5927\u5b66\u201c\u9ad8\u7b49\u5b66\u6821\u5b66\u79d1\u521b\u65b0\u5f15\u667a\u8ba1\u5212\u201d\u5b66\u672f\u5927\u5e08 2015\u5e74\u8d77\u4efb\u5357\u65b9\u79d1\u6280\u5927\u5b66\u5316\u5b66\u7cfb\u7cfb\u4e3b\u4efb\uff0c\u6559\u6388","protected":false},"author":19,"featured_media":12900,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":true,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[212],"tags":[1684,1682,1683],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/01\/01.png","jetpack_shortlink":"https:\/\/wp.me\/p96op1-3m3","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/12899"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=12899"}],"version-history":[{"count":6,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/12899\/revisions"}],"predecessor-version":[{"id":51361,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/12899\/revisions\/51361"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/12900"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=12899"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=12899"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=12899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}