{"id":13630,"date":"2017-04-07T10:21:22","date_gmt":"2017-04-07T02:21:22","guid":{"rendered":"\/\/www.gsbet888.com\/?p=13630"},"modified":"2019-08-02T18:53:23","modified_gmt":"2019-08-02T10:53:23","slug":"eric-j-sorensen","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/chemists\/2017\/04\/eric-j-sorensen.html","title":{"rendered":"Eric J. Sorensen"},"content":{"rendered":"<p style=\"text-align: justify\">\u7ffb\u8bd1\u6295\u7a3f\u00a0<strong>alberto-caeiro<\/strong><\/p>\n<p>Eric J. Sorensen\uff0c\u7f8e\u56fd\u6709\u673a\u5316\u5b66\u5bb6\uff0c\u73b0\u4e3a\u7f8e\u56fd\u666e\u6797\u65af\u987f\u5927\u5b66\u6559\u6388\u3002\uff08\u56fe\u7247\u5f15\u7528\u81ea<a href=\"http:\/\/chemists.princeton.edu\/sorensen\/\">\u7814\u7a76\u5ba4\u4e3b\u9875<\/a>\uff09<\/p>\n<p>&nbsp;<\/p>\n<h4><strong>\u7ecf\u5386<\/strong><\/h4>\n<ul>\n<li>1985-1989\u96ea\u57ce\u5927\u5b66\u5b66\u58eb (Roger Carl Hahn\u6559\u6388)<\/li>\n<li>1990-1995 the University of California, San Diego\u535a\u58eb (K. C. Nicolaou\u6559\u6388)<\/li>\n<li>1995\u20131997 The Memorial Sloan-Kettering Cancer Center\u535a\u58eb\u7814\u7a76\u54e1\uff08S. J. Danishefsky\u6559\u6388\uff09<\/li>\n<li>1997-2001 The Scripps Research Institute \u52a9\u6559\u6388<\/li>\n<li>2001-2003 The Scripps Research Institute \u51c6\u6559\u6388<\/li>\n<li>2003-\u73b0\u5728Princeton University Arthur Allan Ptchett\u6559\u6388<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><strong>\u83b7\u5956\u7ecf\u5386<\/strong><\/h4>\n<ul>\n<li>Beckman Young Investigator Award<\/li>\n<li>a Camille Dreyfus Teacher-Scholar Award<\/li>\n<li>the AstraZeneca Award for Excellence in Chemistry<\/li>\n<li>the Lilly Grantee Award<\/li>\n<li>the Pfizer Global Research Award for Excellence in Organic Chemistry<\/li>\n<li>the Bristol-Myers Squibb Unrestricted Grant in Synthetic Organic Chemistry<\/li>\n<li>2001 Woodward Scholar at Harvard University<\/li>\n<li>2007 Givaudan\/Karrer Distinguished Visiting Professor at the University of Z\u00fcrich<\/li>\n<li>2009 ACS Arthur C. Cope Scholar Award<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><strong>\u7814\u7a76\u6982\u62ec<\/strong><\/h4>\n<p>1 .\u590d\u6742\u5929\u7136\u4ea7\u7269\u7684\u5168\u5408\u6210<\/p>\n<p>\u5728\u76ee\u6807\u5bfc\u5411\u7684Eric J. Sorensen\u7814\u7a76\u5ba4\uff0c\u901a\u8fc7\u8fd0\u7528\u591a\u7c73\u8bfa\u53cd\u5e94\u3001\u751f\u7269\u6a21\u62df\u548cC-H\u952e\u5b98\u80fd\u56e2\u5316\u7b49\u65b9\u6cd5\uff0c\u9ad8\u6548\u7684\u5408\u6210\u4e86\u8bb8\u591a\u5929\u7136\u4ea7\u7269\u53ca\u5176\u78b3\u9aa8\u67b6\uff0c\u5982Abyssomicin C\u3001(+)-FR182877\u3001Jadifenolide\u7b49\u3002<\/p>\n<p>\u901a\u8fc7\u4eff\u751f\u6a21\u62df\u5408\u6210\u7684\u5e94\u7528\uff0cEric J. Sorensen\u7b49\u9ad8\u6548\u7684\u5408\u6210\u4e86\u6beb\u514b\u7ea7\u7684\u5929\u7136\u4ea7\u7269(+)-FR182877\u53ca\u5176\u751f\u7269\u9aa8\u67b6<sup>[1]<\/sup>\uff0c\u5e76\u4e14\u5728\u6b64\u5316\u5408\u7269\u7684\u5408\u6210\u4e2d\uff0c\u9996\u6b21\u5e94\u7528\u4e86\u8de8\u73af\u7684\u53ccD-A\u53cd\u5e94\u3002\u800c\u5728\u5929\u7136\u4ea7\u7269Abyssomicin C\u7684\u5408\u6210\u4e2d\uff0c\u540c\u6837\u4ee5D-A\u53cd\u5e94\u4e3a\u5173\u952e\u6b65\u9aa4\uff0c\u9ad8\u6548\u5408\u6210\u6b64\u5316\u5408\u7269<sup>[2]<\/sup>\u3002\u5316\u5408\u7269Hirsutellone B\u4e5f\u662f\u901a\u8fc7\u65b0\u9896\u800c\u6709\u6548\u7684\u73af\u5316\u4e32\u8054\u53cd\u5e94\u6709\u6548\u7684\u5408\u6210<sup>[3]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/2-13.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-13632 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/2-13.png\" alt=\"\" width=\"497\" height=\"132\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/2-13.png 497w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/2-13-300x80.png 300w\" sizes=\"(max-width: 497px) 100vw, 497px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe1\uff1a\u5168\u5408\u6210\u4ea7\u7269<\/p>\n<p>Eric J. Sorensen\u4e5f\u5c06C-H\u952e\u5b98\u80fd\u56e2\u5316\u5e94\u7528\u4e0e\u5176\u5408\u6210\u5de5\u4f5c\u4e2d\uff0c\u5728Jiadifenolide\u7684\u5168\u5408\u6210\u5de5\u4f5c<sup>[4]<\/sup>\u4e2d\uff0c\u4ee522%\u7684\u6536\u7387\u5f97\u5230\u5b9a\u5411C-H\u952e\u6c27\u5316\u4ea7\u7269\uff1b\u57282016\u5e74\u7684\u4e2d\uff0cEric J. Sorensen\u4e5f\u6709\u4f4d\u70b9\u9009\u62e9\u7684C-H\u952e\u5b98\u80fd\u56e2\u5316\u7684\u5de5\u4f5c<sup>[5]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/3-12.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-13633 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/3-12.png\" alt=\"\" width=\"402\" height=\"139\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/3-12.png 402w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/3-12-300x104.png 300w\" sizes=\"(max-width: 402px) 100vw, 402px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe2\uff1aJiadifenolide\u53ca\u5b9a\u5411C-H\u952e\u6c27\u5316<\/p>\n<p>2 .\u534f\u540c\u6c22\u8f6c\u79fb\u53cd\u5e94<\/p>\n<p>\u53d7\u751f\u547d\u4f53\u7cfb\u4e2d\u9010\u6b65\u8131\u6c22\u7684\u542f\u53d1\uff0cEric J. Sorensen\u7b49\u5f00\u53d1\u4e86\u4e00\u5957\u5728\u5e38\u6e29\u5e38\u538b\u4e0b\uff0c\u7531\u7d2b\u5916\u7ebf\u5f15\u53d1\uff0c\u7ecf\u8fc7\u4e24\u4e2a\u50ac\u5316\u5faa\u73af\u4f53\u7cfb\uff0c\u5728\u50ac\u5316\u91cf\u50ac\u5316\u5242\u4f5c\u7528\u4e0b\u7684\u9010\u6b65\u8131\u6c22\u4f53\u7cfb<sup>[6]<\/sup>\u3002\u5176\u4f53\u7cfb\u4e0e\u4f20\u7edf\u7684\u8131\u6c22\u53cd\u5e94\u4e0d\u540c\uff0c\u4e0d\u9700\u8981\u9ad8\u6e29\u548c\u60f0\u6027\u91d1\u5c5e\uff1b\u4e0e\u751f\u547d\u4f53\u7cfb\u76f8\u6bd4\uff0c\u4e0d\u9700\u8981\u989d\u5916\u7684\u6c27\u5316\u5242\uff0c\u505a\u5230\u4e86\u73af\u4fdd\u4e0e\u9ad8\u6548\uff0c\u5176\u8f6c\u5316\u7387\u6700\u9ad8\u53ef\u8fbe83%\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/4-12.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-13634 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/4-12.png\" alt=\"\" width=\"504\" height=\"278\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/4-12.png 504w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/4-12-300x165.png 300w\" sizes=\"(max-width: 504px) 100vw, 504px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe3\uff1a\u65b0\u4f53\u7cfb\u4e0e\u751f\u7269\u4f53\u7cfb\u53ca\u91d1\u5c5e\u50ac\u5316\u4f53\u7cfb\u5bf9\u6bd4<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/5-10.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-13635 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/5-10.png\" alt=\"\" width=\"498\" height=\"139\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/5-10.png 498w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/5-10-300x84.png 300w\" sizes=\"(max-width: 498px) 100vw, 498px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe4\uff1a\u534f\u540c\u6c22\u8f6c\u79fb\u53cd\u5e94<\/p>\n<h4><strong>\u76f8\u5173\u6587\u732e<\/strong><\/h4>\n<ol>\n<li>\u00a0Vanderwal, C. D.; Vosburg, D. A.; Weiler, S.; Sorensen, E. J. <em>J. Am. Chem. Soc.<\/em> 2003, 125, 5393-5407.<\/li>\n<li>\u00a0Zapf, C. W.; Harrison, B. A.; Drahl, C.; Sorensen, E. J. Angew. Chem. Int. Ed. 2005, 44, 6533-6537.<\/li>\n<li>\u00a0Reber, K. P.; Tilley, S. D.; Carson, C. A.; Sorensen, E. J. J. Org. Chem. 2013, 78, 9584-9607.<\/li>\n<li>\u00a0Siler, D. A.; Mighion, J. D.; Sorensen, E. J. Angew. Chem. Int. Ed. 2014, 53, 5332-5335.<\/li>\n<li>\u00a0Bedell, T.A.; Hone, G.A.B.; Valette, D.; Yu, J.-Q.; Davies, H.M.L.; Sorensen, E.J. Angew. Chem. Int. Ed. 2016, 55, 8270.<\/li>\n<li>\u00a0Julian G. West, David Huang &amp; Erik J. Sorensen Nat. Commun. 2015, 6, 10093.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<h4><strong>\u76f8\u5173\u94fe\u63a5<\/strong><\/h4>\n<p><a href=\"http:\/\/chemists.princeton.edu\/sorensen\/\">\u7814\u7a76\u5ba4\u4e3b\u9875<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/strong> <\/p>\n","protected":false},"excerpt":{"rendered":"\u7ffb\u8bd1\u6295\u7a3f\u00a0alberto-caeiro Eric J. Sorensen\uff0c\u7f8e\u56fd\u6709\u673a\u5316\u5b66\u5bb6\uff0c\u73b0\u4e3a\u7f8e\u56fd\u666e\u6797\u65af\u987f\u5927\u5b66\u6559\u6388\u3002\uff08\u56fe\u7247\u5f15\u7528\u81ea\u7814\u7a76\u5ba4\u4e3b\u9875\uff09 &nbsp; \u7ecf\u5386 1985-1989\u96ea\u57ce\u5927\u5b66\u5b66\u58eb (Roger Carl Hahn\u6559\u6388) 1990-1995 the University of California, San Diego\u535a\u58eb (K. C. Nicolaou\u6559\u6388) 1995\u20131997 The Memorial Sloan-Kettering Cancer Center\u535a\u58eb\u7814\u7a76\u54e1\uff08S. J. Danishefsky\u6559\u6388\uff09 1997-2001 The Scripps Research Institute \u52a9\u6559\u6388 2001-2003 The Scripps Research Institute \u51c6\u6559\u6388 2003-\u73b0\u5728Princeton University Arthur Allan Ptchett\u6559\u6388 &nbsp; \u83b7\u5956\u7ecf\u5386 Beckman Young Investigator Award a Camille Dreyfus Teacher-Scholar Award the AstraZeneca Award for Excellence in Chemistry the Lilly Grantee Award the Pfizer Global Research Award for Excellence in Organic Chemistry the Bristol-Myers Squibb Unrestricted Grant in Synthetic Organic Chemistry 2001 Woodward Scholar at Harvard University 2007 Givaudan\/Karrer Distinguished Visiting Professor at the University of Z\u00fcrich 2009 ACS Arthur C. Cope Scholar Award &nbsp; [&hellip;]","protected":false},"author":8,"featured_media":13631,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[212],"tags":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/03\/1-12.png","jetpack_shortlink":"https:\/\/wp.me\/p96op1-3xQ","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/13630"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=13630"}],"version-history":[{"count":2,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/13630\/revisions"}],"predecessor-version":[{"id":27466,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/13630\/revisions\/27466"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/13631"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=13630"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=13630"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=13630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}