{"id":15124,"date":"2017-08-10T06:56:45","date_gmt":"2017-08-09T22:56:45","guid":{"rendered":"\/\/www.gsbet888.com\/?p=15124"},"modified":"2019-08-02T18:52:55","modified_gmt":"2019-08-02T10:52:55","slug":"snap-%e8%af%95%e5%89%82","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/reactions\/%e7%8e%af%e5%8c%96%e5%8f%8d%e5%ba%94\/2017\/08\/snap-%e8%af%95%e5%89%82.html","title":{"rendered":"SnAP \u8bd5\u5242"},"content":{"rendered":"

\u672c\u6587\u6295\u7a3f\u4f5c\u8005 alberto-caeiro<\/strong><\/p>\n

 <\/p>\n

\u901a\u8fc7\u5c06SnAP (Sn(tin) Amine Protocol)\u8bd5\u5242\u548c\u7fb0\u57fa\u5316\u5408\u7269\u6df7\u5408\u540e\u7ecf\u9178\u5316\u5904\u7406\uff0c\u6211\u4eec\u53ef\u4ee5\u8f7b\u677e\u5f97\u5230\u542b\u6709\u9971\u548c\u7684\u5076\u6570\u73af\uff0c\u87ba\u73af\u7b49\u7ed3\u6784\u7684\u6c28\u57fa\u5316\u5408\u7269\u3002\u76ee\u524d\uff0c\u5404\u79cd\u5404\u6837\u7684SnAP\u6b63\u5728\u5e02\u573a\u8d29\u5356\u4e2d\u3002<\/a><\/p>\n

\u5f53\u836f\u7269\u5206\u5b50\u7684\u9971\u548c\u5ea6\uff08sp3<\/sup>\u6742\u5316\u78b3\u7684\u542b\u91cf\uff09\u589e\u52a0\u65f6\uff0c\u5bf9\u836f\u7269\u7684\u7279\u6027\u4f1a\u6709\u6b63\u5411\u7684\u5f71\u54cd<\/a>\u3002<\/p>\n

\u57fa\u672c\u6587\u732e<\/strong><\/h4>\n
    \n
  1. Vo, C.-V.; Mikutis, G.; Bode, J. W. Angew. Chem. Int. Ed. 2013, 52, 1705.\u00a0DOI: 10.1002\/anie.201208064<\/a>;<\/li>\n
  2. Luescher, M. U.; Vo, C.-V.; Bode, J. W. Org. Lett. 2014, 16, 1236.\u00a0DOI: 10.1021\/ol500210z<\/a>;<\/li>\n
  3. Vo, C.-V.; Luescher, M. U.; Bode, J. W. Nat. Chem. 2014, 6, 310.\u00a0DOI:10.1038\/nchem.1878<\/a>;<\/li>\n
  4. Siau, W.-Y.; Bode, J. W. J. Am. Chem. Soc. 2014, 136, 17726.\u00a0DOI: 10.1021\/ja511232b<\/a>;<\/li>\n
  5. Geoghegan, K.; Bode, J. W. Org. Lett. 2015, 17, 1934.\u00a0DOI: 10.1021\/acs.orglett.5b00618<\/a>;<\/li>\n
  6. Luescher, M. U.; Bode, J. W. Angew. Chem. Int. Ed. 2015, 54, 10884.\u00a0DOI: 10.1002\/anie.201505167<\/a>;<\/li>\n
  7. Luescher, M. U.; Bode, J. W. Org. Lett. 2016, 18, 2652.\u00a0DOI: 10.1021\/acs.orglett.6b01099<\/a>;<\/li>\n<\/ol>\n

    review<\/em><\/strong><\/h4>\n
      \n
    1. Vo, C.-V.; Bode, J. W. J. Org. Chem. 2014, 79, 2809. DOI: 10.1021\/jo5001252<\/a><\/li>\n
    2. Luescher, M. U.; Geoghegan, K.; Nichols, P. L.; Bode, J. W. Aldrichim. Acta 2015, 48, 43. [PDF<\/a>]<\/li>\n<\/ol>\n

       <\/p>\n

      \u53cd\u5e94\u673a\u7406<\/strong><\/h4>\n

      \"\"<\/a><\/p>\n

      \u53cd\u5e94\u5b9e\u4f8b<\/strong><\/h4>\n
        \n
      1. \u5bf9\u4e8e\u4e0e\u916e\u7c7b\u5316\u5408\u7269\u7684\u53cd\u5e94\uff0c\uff0c\u901a\u8fc7\u6b64\u8bd5\u5242\u53ef\u4ee5\u5f97\u5230\u7ed3\u6784\u590d\u6742\u7684\u87ba\u73af\u7ed3\u6784\u5316\u5408\u7269\u3002<\/li>\n<\/ol>\n

        \"\"<\/a><\/p>\n

          \n
        1. \u57fa\u4e8eSnAP\u8bd5\u5242\uff0c\u5f00\u53d1\u51fa\u4e0d\u542b\u6709\u673a\u9521\u3001\u5728\u5149\u7167\u6761\u4ef6\u4e0b\uff0cSi\u81ea\u7531\u57fa\u7684SLAP\u8bd5\u5242 (Silicon amine protocol)<\/strong>[1]<\/li>\n<\/ol>\n

          \"\"<\/a><\/p>\n

          \u53c2\u8003\u6587\u732e<\/strong><\/h4>\n
            \n
          1. Hsieh, S.-Y.; Bode, J. W. Org. Lett. 2016, 18, 2098. DOI: 10.1021\/acs.orglett.6b00722<\/a>;<\/li>\n
          2. Hsieh, S-H.; Bode, J. W. ACS Cent. Sci. 2017, 3, 66. DOI: 10.1021\/acscentsci.6b00334<\/a>;<\/li>\n<\/ol>\n

            \u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/strong> <\/p>\n","protected":false},"excerpt":{"rendered":"\u672c\u6587\u6295\u7a3f\u4f5c\u8005 alberto-caeiro   \u901a\u8fc7\u5c06SnAP (Sn(tin) Amine Protocol)\u8bd5\u5242\u548c\u7fb0\u57fa\u5316\u5408\u7269\u6df7\u5408\u540e\u7ecf\u9178\u5316\u5904\u7406\uff0c\u6211\u4eec\u53ef\u4ee5\u8f7b\u677e\u5f97\u5230\u542b\u6709\u9971\u548c\u7684\u5076\u6570\u73af\uff0c\u87ba\u73af\u7b49\u7ed3\u6784\u7684\u6c28\u57fa\u5316\u5408\u7269\u3002\u76ee\u524d\uff0c\u5404\u79cd\u5404\u6837\u7684SnAP\u6b63\u5728\u5e02\u573a\u8d29\u5356\u4e2d\u3002 \u5f53\u836f\u7269\u5206\u5b50\u7684\u9971\u548c\u5ea6\uff08sp3\u6742\u5316\u78b3\u7684\u542b\u91cf\uff09\u589e\u52a0\u65f6\uff0c\u5bf9\u836f\u7269\u7684\u7279\u6027\u4f1a\u6709\u6b63\u5411\u7684\u5f71\u54cd\u3002 \u57fa\u672c\u6587\u732e Vo, C.-V.; Mikutis, G.; Bode, J. W. Angew. Chem. Int. Ed. 2013, 52, 1705.\u00a0DOI: 10.1002\/anie.201208064; Luescher, M. U.; Vo, C.-V.; Bode, J. W. Org. Lett. 2014, 16, 1236.\u00a0DOI: 10.1021\/ol500210z; Vo, C.-V.; Luescher, M. U.; Bode, J. W. Nat. Chem. 2014, 6, 310.\u00a0DOI:10.1038\/nchem.1878; Siau, W.-Y.; Bode, J. W. J. Am. Chem. Soc. 2014, 136, 17726.\u00a0DOI: 10.1021\/ja511232b; Geoghegan, K.; Bode, J. W. Org. Lett. 2015, 17, 1934.\u00a0DOI: 10.1021\/acs.orglett.5b00618; Luescher, M. U.; Bode, J. W. Angew. Chem. Int. Ed. 2015, 54, 10884.\u00a0DOI: 10.1002\/anie.201505167; Luescher, M. U.; Bode, J. W. Org. Lett. 2016, 18, 2652.\u00a0DOI: 10.1021\/acs.orglett.6b01099; review Vo, C.-V.; Bode, J. W. J. Org. Chem. […]","protected":false},"author":8,"featured_media":15015,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[9,99],"tags":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/07\/SnAP_1-e1499528885162.png","jetpack_shortlink":"https:\/\/wp.me\/p96op1-3VW","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/15124"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=15124"}],"version-history":[{"count":2,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/15124\/revisions"}],"predecessor-version":[{"id":27365,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/15124\/revisions\/27365"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/15015"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=15124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=15124"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=15124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}