{"id":16165,"date":"2017-10-04T20:48:32","date_gmt":"2017-10-04T12:48:32","guid":{"rendered":"\/\/www.gsbet888.com\/?p=16165"},"modified":"2019-08-02T18:52:34","modified_gmt":"2019-08-02T10:52:34","slug":"richard-henderson","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/chemists\/2017\/10\/richard-henderson.html","title":{"rendered":"Richard Henderson"},"content":{"rendered":"<p>Richard Henderson\u00a01945\u5e747\u670819\u65e5~\uff0c\u82f1\u56fd\u7684\u5206\u5b50\u751f\u7269\u5b66\u5bb6\u3002MRC\u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\u6240Programme Leader\u30022017\u5e74\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u5f97\u4e3b\u4e4b\u4e00\u3002<\/p>\n<h4>\u5c65\u5386<\/h4>\n<p>1966 \u7231\u4e01\u5821\u5927\u5b66\u6bd5\u4e1a(\u7269\u7406\u5b66)<br \/>\n1969 \u5251\u6865\u5927\u5b66\u535a\u58eb\u6bd5\u4e1a (MRC\u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\u6240, David Blow\u6559\u6388)<br \/>\n1969 MRC\u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\u6240\u7814\u7a76\u5458<br \/>\n1970 \u8036\u9c81\u5927\u5b66\u535a\u58eb\u7814\u7a76\u5458(Helen Hay Whitney\u6559\u6388)<br \/>\n1973- MRC Laboratory of Molecular Biology, Cambridge<br \/>\n1973 \u00a0MRC\u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\u6240\u7814\u7a76\u5458(Research Staff)<br \/>\n1979 \u540c\u4e0a\u4e0a\u5e2d\u7814\u7a76\u5458\uff08Senior Research Staff\uff09<br \/>\n1984 Special Appointments Grade Research Staff<br \/>\n1986 Joint Head of Division of Structural Studies<br \/>\n1995 \u526f\u6240\u9577<br \/>\n1986 \u6240\u9577<br \/>\n2006 Programme Leader<\/p>\n<h4>\u83b7\u5956\u7ecf\u5386<\/h4>\n<p>1978 William Bate Hardy Prize<br \/>\n1984 Sir Hans Krebs Medal by the Federation of European Biochemical Societies<br \/>\n1981 Ernst-Ruska Prize for Electron Microscopy<br \/>\n1991 Lewis S. Rosenstiel Award<br \/>\n1993 Louis-Jeantet Prize for Medicine<br \/>\n1999 Gregori Aminoff prize (together with Nigel Unwin)<br \/>\n2005 Distinguished Scientist Award and Fellow, Microscopy Society of America<br \/>\n2016 Copley Medal of the Royal Society[7] 2016 Alexander Hollaender Award in Biophysics<br \/>\n2017 Nobel Prize in Chemistry<\/p>\n<h4>\u7814\u7a76\u6982\u8981<\/h4>\n<p id=\"tw-target-text\" class=\"tw-data-text tw-ta tw-text-small\" dir=\"ltr\" data-placeholder=\"\u7ffb\u8a33\"><strong><span lang=\"ja\">\u5229\u7528Cryo-electron microscopy\uff08CryoEM\u3001\u51b7\u51bb\u7535\u955c\uff09\u8fdb\u884c\u5de8\u5927\u5206\u5b50\u7684\u539f\u5b50\u7ea7\u6784\u9020\u89e3\u6790<\/span><\/strong><\/p>\n<p>1975\u5e74\u4e3a\u4e86\u6311\u6218\u819c\u86cb\u767d\u7684\u6784\u9020\u89e3\u6790\uff0c\u5f00\u53d1\u51fa\u4e86\u5c06\u819c\u86cb\u767d\u4e0e\u819c\u4e00\u8d77\u653e\u7f6e\u5728\u7535\u5b50\u663e\u5fae\u955c\u4e2d\uff0c\u540c\u65f6\u7528\u8461\u8404\u7cd6\u6eb6\u6db2\u4f5c\u4e3a\u4fdd\u62a4\u6db2\u907f\u514d\u5e72\u71e5\uff0c\u7528\u5f31\u7535\u5b50\u675f\u4e00\u8fb9\u7167\u5c04\u4e00\u8fb9\u7528\u7535\u5b50\u663e\u5fae\u955c\u89c2\u5bdf\u7684\u624b\u6cd5\u3002<\/p>\n<p>\u5229\u7528\u4ee5\u4e0a\u65b9\u6cd5\u8fdb\u884c\u4e86\u7ec6\u83cc\u89c6\u7d2b\u7ea2\u8d28\u7684\u4e8c\u7ef4\u7ed3\u6676\u7684\u7535\u5b50\u884d\u5c04\u5b9e\u9a8c\u5de5\u4f5c\uff0c\u867d\u7136\u6700\u521d\u89c2\u6d4b\u5230\u7684\u662f\u6a21\u7cca\u7684\u56fe\u50cf\uff08\u5206\u8fa8\u73877\u00c5\uff09\uff0c\u4f46\u662f\u4ece\u8be5\u56fe\u50cf\u786e\u5b9a\u4e86\u7ec6\u83cc\u89c6\u7d2b\u7ea2\u8d28\u662f\u75317\u4e2a\u03b1\u87ba\u65cb\u7ed3\u6784\u7a7f\u900f\u819c\u86cb\u767d\u300215\u5e74\u540e\uff0c\u5728\u4e0d\u65ad\u5730\u6478\u7d22\uff0c\u6539\u5584\u540e\uff0c\u7ec8\u4e8e\u9996\u6b21\u89c2\u6d4b\u5230\u4e86\u539f\u5b50\u7ea7\u522b\u7684\u7ec6\u83cc\u89c6\u7d2b\u7ea2\u8d28\u7684\u7ed3\u6784\u3002\u8fd9\u662f\u7535\u5b50\u663e\u5fae\u955c\u5728\u86cb\u767d\u8d28\u89c2\u6d4b\uff0c\u89e3\u6790\u9886\u57df\u7684\u6700\u9ad8\u7684\u6210\u679c\u3002\u5e76\u4e14\u8bc1\u660e\u4e86\u51b7\u51bb\u7535\u955c<span lang=\"ja\">\u4e0eX\u5c04\u7ebf\u5355\u6676\u884d\u5c04\u4e00\u6837\uff0c\u53ef\u4ee5\u8fbe\u5230\u89e3\u50cf\u5ea63\u00c5\u7684\u6210\u50cf\u89c2\u6d4b\u3002<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-16167\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/10\/1m0l_opm.png\" alt=\"\" width=\"220\" height=\"223\" \/><\/p>\n<h4>\u76f8\u5173\u52a8\u753b<\/h4>\n<p><span class=\"embed-youtube\"><span class=\"embed-youtube\" style=\"text-align:center; display: block;\"><iframe loading=\"lazy\" class=\"youtube-player\" width=\"640\" height=\"360\" src=\"https:\/\/www.youtube.com\/embed\/xiuZ-armcdY?version=3&#038;rel=1&#038;showsearch=0&#038;showinfo=1&#038;iv_load_policy=1&#038;fs=1&#038;hl=en-US&#038;autohide=2&#038;wmode=transparent\" allowfullscreen=\"true\" style=\"border:0;\" sandbox=\"allow-scripts allow-same-origin allow-popups allow-presentation allow-popups-to-escape-sandbox\"><\/iframe><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<h4>\u76f8\u5173\u6587\u732e<\/h4>\n<ol>\n<li>(a) Unwin, P. N. T., and Henderson, R. (1975) Molecular structure determination by electron microscopy of unstained crystalline specimens. <i>J. Mol. Biol. <\/i><b>94<\/b>, 425-43. (b)\u00a0Henderson, R., and Unwin, P. N. T. (1975) Three-dimensional model of purple membrane obtained by electron microscopy. <i>Nature <\/i><b>257<\/b>, 28-32.<\/li>\n<li>Henderson, R.; Baldwin, J. M.; Ceska, T. A.; Zemlin, F.; Beckmann, E.; Downing, K. H. <i>J Mol Biol<\/i> <b>1990<\/b>, <i>213<\/i> (4), 899\u2013929. DOI:\u00a0<a class=\"doi\" title=\"Persistent link using digital object identifier\" href=\"https:\/\/doi.org\/10.1016\/S0022-2836(05)80271-2\" target=\"_blank\" rel=\"noopener\" aria-label=\"Persistent link using digital object identifier\">10.1016\/S0022-2836(05)80271-2<\/a><\/li>\n<\/ol>\n<h4>\u76f8\u5173\u94fe\u63a5<\/h4>\n<ul>\n<li><a href=\"http:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/rh15\/\">R Henderson home<\/a><\/li>\n<\/ul>\n<p><strong>\u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/strong> <\/p>\n","protected":false},"excerpt":{"rendered":"Richard Henderson\u00a01945\u5e747\u670819\u65e5~\uff0c\u82f1\u56fd\u7684\u5206\u5b50\u751f\u7269\u5b66\u5bb6\u3002MRC\u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\u6240Programme Leader\u30022017\u5e74\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u5f97\u4e3b\u4e4b\u4e00\u3002 \u5c65\u5386 1966 \u7231\u4e01\u5821\u5927\u5b66\u6bd5\u4e1a(\u7269\u7406\u5b66) 1969 \u5251\u6865\u5927\u5b66\u535a\u58eb\u6bd5\u4e1a (MRC\u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\u6240, David Blow\u6559\u6388) 1969 MRC\u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\u6240\u7814\u7a76\u5458 1970 \u8036\u9c81\u5927\u5b66\u535a\u58eb\u7814\u7a76\u5458(Helen Hay Whitney\u6559\u6388) 1973- MRC Laboratory of Molecular Biology, Cambridge 1973 \u00a0MRC\u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\u6240\u7814\u7a76\u5458(Research Staff) 1979 \u540c\u4e0a\u4e0a\u5e2d\u7814\u7a76\u5458\uff08Senior Research Staff\uff09 1984 Special Appointments Grade Research Staff 1986 Joint Head of Division of Structural Studies 1995 \u526f\u6240\u9577 1986 \u6240\u9577 2006 Programme Leader \u83b7\u5956\u7ecf\u5386 1978 William Bate Hardy Prize 1984 Sir Hans Krebs Medal by the Federation of European Biochemical Societies 1981 Ernst-Ruska Prize for Electron Microscopy 1991 Lewis S. Rosenstiel Award 1993 Louis-Jeantet Prize for Medicine 1999 Gregori Aminoff prize (together with Nigel Unwin) 2005 Distinguished Scientist Award and Fellow, Microscopy Society of America 2016 Copley Medal of the Royal [&hellip;]","protected":false},"author":5,"featured_media":16166,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[212],"tags":[2052,2053],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/10\/2017-10-04_20-54-43.png","jetpack_shortlink":"https:\/\/wp.me\/p96op1-4cJ","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/16165"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=16165"}],"version-history":[{"count":4,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/16165\/revisions"}],"predecessor-version":[{"id":27294,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/16165\/revisions\/27294"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/16166"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=16165"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=16165"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=16165"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}