{"id":17393,"date":"2018-01-16T06:20:49","date_gmt":"2018-01-15T22:20:49","guid":{"rendered":"\/\/www.gsbet888.com\/?p=17393"},"modified":"2019-08-02T18:52:10","modified_gmt":"2019-08-02T10:52:10","slug":"org-lett-%e4%b8%8d%e5%af%b9%e7%a7%b0%e8%84%b1%e6%b0%a2diels-alder%e5%8f%8d%e5%ba%94%e5%90%88%e6%88%90%e6%89%8b%e6%80%a7%e5%9b%9b%e6%b0%a2%e5%92%94%e5%94%91%e8%a1%8d%e7%94%9f%e7%89%a9%ef%bc%88","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/recentpaper\/2018\/01\/org-lett-%e4%b8%8d%e5%af%b9%e7%a7%b0%e8%84%b1%e6%b0%a2diels-alder%e5%8f%8d%e5%ba%94%e5%90%88%e6%88%90%e6%89%8b%e6%80%a7%e5%9b%9b%e6%b0%a2%e5%92%94%e5%94%91%e8%a1%8d%e7%94%9f%e7%89%a9%ef%bc%88.html","title":{"rendered":"Org. Lett. \u4e0d\u5bf9\u79f0\u8131\u6c22Diels-Alder\u53cd\u5e94\u5408\u6210\u624b\u6027\u56db\u6c22\u5494\u5511\u884d\u751f\u7269\uff08\u5408\u80a5\u5de5\u4e1a\u5927\u5b66\uff09"},"content":{"rendered":"<h4>\u6458\u8981<\/h4>\n<p>\u5408\u80a5\u5de5\u4e1a\u5927\u5b66\u5434\u7965\u8bfe\u9898\u7ec4\uff08<a href=\"http:\/\/hgxy.hfut.edu.cn\/website\/index.php\/cn\/staff\/associate-professor\/item\/2329-2015-10-13-03-32-10\">\u4e3b\u9875<\/a>\uff09\u8fd1\u65e5\u53d1\u5c55\u4e86\u4e00\u79cd\u65b0\u9896\u7684\u4e0d\u5bf9\u79f0\u8131\u6c22Diels-Alder\u53cd\u5e94\u3002\u8be5\u53cd\u5e94\u5e95\u7269\u8303\u56f4\u5e7f\uff0c\u7acb\u4f53\u9009\u62e9\u6027\u9ad8\uff0c\u53ef\u4e3a\u5176\u4ed6\u73cd\u8d35\u624b\u6027\u5316\u5408\u7269\u7684\u5408\u6210\u63d0\u4f9b\u53c2\u8003\u3002<\/p>\n<blockquote><p>An Asymmetric Dehydrogenative Diels\u2013Alder Reaction for the Synthesis of Chiral Tetrahydrocarbazole Derivatives<\/p>\n<p>Xiang Wu* , Hai-Jie Zhu, Shi-Bao Zhao, Shu-Sen Chen, Yun-Fei Luo, and You-Gui Li<\/p>\n<p><em>Org. Lett.<\/em>, <strong>2018<\/strong>, <em>20<\/em>, 32\u201335.\u00a0<a href=\"http:\/\/pubs.acs.org\/doi\/10.1021\/acs.orglett.7b03251\">DOI\uff1a10.1021\/acs.orglett.7b03251<\/a><\/p><\/blockquote>\n<h4>\u5bfc\u5e08\u7b80\u4ecb\uff08\u5f15\u7528\u81ea\u5408\u80a5\u5de5\u4e1a\u5927\u5b66\u5b98\u7f51\uff09<\/h4>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17694\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/wuxiang-214x300.jpg\" alt=\"\" width=\"156\" height=\"219\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/wuxiang-214x300.jpg 214w, https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/wuxiang-680x952.jpg 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/wuxiang.jpg 700w\" sizes=\"(max-width: 156px) 100vw, 156px\" \/><\/p>\n<p style=\"text-align: center\"><strong>\u5434\u7965<\/strong><\/p>\n<p>2001.09-2005.06\uff0c\u5357\u5f00\u5927\u5b66\u5316\u5b66\u5b66\u9662\uff0c\u7406\u79d1\u57fa\u5730\u73ed\uff0c\u672c\u79d1<br \/>\n2005.09-2010.12\uff0c\u5357\u5f00\u5927\u5b66\u5143\u7d20\u6709\u673a\u56fd\u5bb6\u91cd\u70b9\u5b9e\u9a8c\u5ba4\uff0c\u535a\u58eb<br \/>\n2010.12-2012.08\uff0c\u82cf\u5dde\u8bfa\u534e\u5236\u836f\u79d1\u6280\u6709\u9650\u516c\u53f8\uff0c\u9ad8\u7ea7\u7814\u7a76\u5458<br \/>\n2012.08-2014.12\uff0c\u4e2d\u56fd\u79d1\u5b66\u6280\u672f\u5927\u5b66\u5fae\u5c3a\u5ea6\u7269\u8d28\u79d1\u5b66\u56fd\u5bb6\u5b9e\u9a8c\u5ba4\uff0c\u535a\u58eb\u540e<br \/>\n2014.12-2015.08\uff0c\u7f8e\u56fd\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5dde\u7acb\u5927\u5b66\u5316\u5b66\u7cfb\uff0c\u535a\u58eb\u540e<\/p>\n<p>2015.08-\u81f3\u4eca\uff0c\u5408\u80a5\u5de5\u4e1a\u5927\u5b66\u5316\u5b66\u4e0e\u5316\u5de5\u5b66\u9662\u5e94\u7528\u5316\u5b66\u7cfb\uff0c\u526f\u7814\u7a76\u5458<\/p>\n<p>&nbsp;<\/p>\n<h4>\u4e00\u3001\u7814\u7a76\u80cc\u666f<\/h4>\n<p>C-H\u952e\u7684\u76f4\u63a5\u5b98\u80fd\u56e2\u5316\u662f\u901a\u8fc7\u6613\u5f97\u539f\u6599\u5408\u6210\u590d\u6742\u5206\u5b50\u7684\u4e00\u79cd\u5f3a\u6709\u529b\u7684\u65b9\u6cd5<sup>[1]<\/sup>\u3002\u4e24\u4e2aC-H\u952e\u7684\u4ea4\u53c9\u8131\u6c22\u5076\u8054\uff08cross dehydrogenative coupling\uff0cCDC\uff09\u662f\u9ad8\u6548\u6784\u5efaC-C\u952e\u7684\u53e6\u4e00\u7b56\u7565<sup>[2]<\/sup>\u3002\u5c24\u5176\u8981\u63d0\u7684\u662f\uff0c\u8131\u6c22\u540e\u4ea7\u751f\u7684\u591a\u79cd\u591a\u6837\u7684\u53cc\u70ef\u7528\u4e8eDiels-Alder\u53cd\u5e94\u5df2\u7ecf\u6210\u4e3a\u4e00\u6b65\u6784\u5efa\u516d\u5143\u78b3\u73af\u7684\u72ec\u7279\u65b9\u6cd5<sup>[3]<\/sup>\u30022011\u5e74<a href=\"\/\/www.gsbet888.com\/chemists\/2015\/04\/m-christina-white.html\">White<\/a>\u7b49\u4eba\u62a5\u9053\u4e86Pd\u50ac\u5316\u4e0b\u672b\u7aef\u70ef\u70c3\u70ef\u4e19\u4f4dC-H\u952e\u8131\u6c22\u6c27\u5316\u5f62\u6210\u53cc\u70ef\u7684\u65b9\u6cd5<sup>[4]<\/sup>\u3002\u53cc\u70ef\u548c\u70ef\u916e\u7684Diels-Alder\u53cd\u5e94\u4e5f\u4f7fBrosimonesA\u548cB\u7684\u5168\u5408\u6210\u5f97\u4ee5\u5b9e\u73b0\u3002\u6700\u8fd1\uff0cAntonchick\u7ec4\u6210\u529f\u5730\u5c06\u53cc\u70ef\u524d\u4f53\u8303\u56f4\u6269\u5c55\u5230\u7b80\u5355\u7684\u82b3\u70f7\u70c3\uff0c\u591a\u79cd\u7f3a\u7535\u5b50\u7684\u70ef\u70c3\u4f5c\u4e3a\u4eb2\u53cc\u70ef\u4f53\u53c2\u4e0e\u6b64Diels-Alder\u53cd\u5e94<sup>[5]<\/sup>\u3002<\/p>\n<p>\u4f5c\u4e3a\u4e00\u4e2a\u72ec\u7279\u7684\u7ed3\u6784\u6a21\u5757\uff0c\u56db\u6c22\u5494\u5511\u5305\u542b\u591a\u4e2a\u7acb\u4f53\u4e2d\u5fc3\uff0c\u5e7f\u6cdb\u5b58\u5728\u4e8e\u5929\u7136\u7684\u5432\u54da\u751f\u7269\u78b1\u548c\u5408\u6210\u836f\u7269\uff0c\u5b83\u4eec\u5177\u6709\u591a\u79cd\u91cd\u8981\u7684\u751f\u7269\u6d3b\u6027\uff08\u56fe1\uff0cB\uff09\u3002\u629b\u5f00\u5408\u6210\u56db\u6c22\u5494\u5511\u884d\u751f\u7269\u53d6\u5f97\u7684\u8fdb\u6b65\uff0c\u65b0\u9896\u548c\u66f4\u52a0\u9ad8\u6548\u5730\u5408\u6210\u591a\u6837\u5316\u56db\u6c22\u5494\u5511\u7ed3\u6784\u7684\u65b9\u6cd5\u5728\u6709\u673a\u548c\u533b\u836f\u5316\u5b66\u9886\u57df\u4ecd\u7136\u8feb\u5207\u9700\u8981\u3002\u8131\u6c22Diels-Alder\u53cd\u5e94\u5df2\u7ecf\u88ab\u7528\u4e8e\u56db\u6c22\u5494\u5511\u7684\u5408\u6210\uff0cZhang\u7b49\u4eba\u53d1\u73b0DDQ\u4fc3\u8fdb2-\u7532\u57fa-3-\u82b3\u7532\u57fa\u548c\u4eb2\u53cc\u70ef\u4f53\u7684Diels-Alder\u53cd\u5e94\u7ecf\u5386\u7684\u662findole-2,3-quinodimethane\u9014\u5f84\uff08\u56fe1\uff0cA\uff09<sup>[6]<\/sup>\u3002\u8bfe\u9898\u7ec4\u7684\u5174\u8da3\u662f\u4e0d\u5bf9\u79f0\u6c27\u5316C-H\u952e\u5b98\u80fd\u56e2\u5316\uff0c\u56e0\u6b64\u4ed6\u4eec\u5e0c\u671b\u5b9e\u73b0\u6b64\u53cd\u5e94\u7684\u5bf9\u6620\u9009\u62e9\u6027\u3002\u6c27\u5316\u6cd5\u6784\u5efa\u624b\u6027\u56db\u6c22\u5494\u5511\u6ca1\u6709\u5148\u4f8b\u4e3b\u8981\u539f\u56e0\u53ef\u80fd\u662f\uff081\uff09\u6c27\u5316\u5242\u4e0e\u624b\u6027\u50ac\u5316\u5242\u4e4b\u95f4\u7684\u517c\u5bb9\u95ee\u9898\uff1b\uff082\uff09\u8fc7\uff08\u5ea6\uff09\u6c27\u5316\u95ee\u9898\u3002\u56e0\u6b64\uff0c\u672c\u6587\u62a5\u9053\u4e862-\u7532\u57fa-3-\u82b3\u7532\u57fa\u5432\u54da\u548c\u03b1,\u03b2-\u4e0d\u9971\u548c\u919b\u7684\u9996\u4f8b\u4e0d\u5bf9\u79f0\u8131\u6c22Diels-Alder\u53cd\u5e94\uff08\u56fe1\uff0cC\uff09\u3002\u901a\u8fc7\u624b\u6027\u4e8c\u7ea7\u80fa\u50ac\u5316\u5242\u964d\u4f4e\u4e0d\u9971\u548c\u919bLUMO\u8f68\u9053\u80fd\u91cf\u8fd9\u79cd\u7ecf\u5178\u7684\u6d3b\u5316\u65b9\u5f0f\uff0c\u6b64\u53cd\u5e94\u53ef\u4ee5\u5b9e\u73b0\u6781\u597d\u7684\u7acb\u4f53\u63a7\u5236\uff0c\u5f97\u5230\u5e26\u6709\u4e09\u4e2a\u76f8\u90bb\u624b\u6027\u4e2d\u5fc3\u7684\u5149\u5b66\u7eaf\u7684\u56db\u6c22\u5494\u5511\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/1-12.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17394 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/1-12.png\" alt=\"\" width=\"644\" height=\"594\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/1-12.png 644w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/1-12-300x277.png 300w\" sizes=\"(max-width: 644px) 100vw, 644px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe 1\u5408\u6210\u56db\u6c22\u5494\u5511\u7684\u8131\u6c22Diels-Alder\u53cd\u5e94<\/p>\n<h4>\u4e8c\u3001\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316<\/h4>\n<p>\u8bfe\u9898\u7ec4\u4eba\u5458\u57284\u00c5MS\u5b58\u5728\u4e0b\uff0c\u4ee53-\u82c4\u57fa-2-\u7532\u57fa-1<em>H<\/em>-\u5432\u54da\uff08<strong>2a<\/strong>\uff09\u548c\u8089\u6842\u919b\uff08<strong>3a<\/strong>\uff09\u4e3a\u5e95\u7269\uff0cDDQ\u4f5c\u4e3a\u6c27\u5316\u5242\uff0c\u03b1,\u03b1-\u4e8c\u82ef\u57fa\u812f\u6c28\u9178\u4e09\u7532\u57fa\u7845\u919a\uff08<strong>1<\/strong>\uff09\/\u82ef\u7532\u9178\u4f5c\u4e3a\u50ac\u5316\u5242\u5efa\u7acb\u6a21\u578b\u53cd\u5e94\u300250\u2103\u4e0b\uff0cCHCl<sub>3<\/sub>\u4e2d\u8fdb\u884c\u7684\u53cd\u5e94\u53d6\u5f97\u8f83\u4e3a\u4e0d\u9519\u7684\u7ed3\u679c\uff0cNaBH<sub>4<\/sub>\u8fd8\u539f\u4e4b\u540e\u89c2\u5bdf\u52303:1\u7684<em>dr<\/em>\u503c\uff0c\u4e3b\u8981\u7684\u975e\u5bf9\u6620\u4f53<strong>4aa<\/strong>\u5206\u79bb\u4ea7\u738757%\uff0c<em>ee<\/em>\u503c\u9ad8\u8fbe99%\uff0c\u4ec5\u6709\u5c11\u91cf\u7684\u6c27\u5316\u526f\u4ea7\u72693-\u82ef\u7532\u9170\u57fa-2-\u7532\u57fa-1<em>H<\/em>-\u5432\u54da\u751f\u6210\uff08\u88681\uff0centry 1\uff09\u3002\u6539\u53d8\u4e0d\u540c\u7684Br\u00f8nsted\u9178\uff0c\u4ea7\u7387\u964d\u4f4e\uff08entries 2-4\uff09\u3002\u503c\u5f97\u63d0\u51fa\u7684\u662f\u4e00\u4e2a\u5f3a\u7684Br\u00f8nsted\u9178\u4f1a\u63d0\u9ad8\u53cd\u5e94\u7684\u975e\u5bf9\u6620\u9009\u62e9\u6027\uff08entries 2,4 vs 1\uff09\u3002\u7b5b\u9009\u6eb6\u5242\u65f6\u53d1\u73b0\uff0c\u5728DCE\u3001THF\u3001\u7532\u82ef\u548cDMSO\u4e2d\uff0cCHCl<sub>3<\/sub>\u4ecd\u7136\u662f\u6700\u597d\u7684\u6eb6\u5242\uff08entries 5-8 vs 1\uff09\u3002\u4e3a\u4e86\u63d0\u9ad8\u975e\u5bf9\u6620\u9009\u62e9\u6027\uff0c\u8bfe\u9898\u7ec4\u4eba\u5458\u63a2\u7a76\u4e86\u6dfb\u52a0\u5242\u7684\u4f5c\u7528\uff0c\u50ac\u5316\u91cf\u7684\u8fc7\u6e21\u91d1\u5c5e\u76d0\u786e\u5b9e\u63d0\u9ad8\u4e86<em>dr<\/em>\u503c\uff08entries 9-12\uff09\u3002\u4f8b\u5982\uff0c\u52a0\u516520 mol%\u7684CuCl<sub>2<\/sub>\u6216NiCl<sub>2<\/sub>\u4f1a\u5f97\u5230\u5927\u4e8e10:1\u7684dr\u503c\uff0c\u7136\u800c\u662f\u4ee5\u964d\u4f4e\u5bf9\u6620\u9009\u62e9\u6027\u4e3a\u4ee3\u4ef7\u7684\uff08entries 9-10\uff09\u3002Pd(OAc)<sub>2<\/sub>\u5728\u975e\u5bf9\u6620\u9009\u62e9\u6027\u548c\u5bf9\u6620\u9009\u62e9\u6027\u4e0a\u90fd\u80fd\u53d6\u5f97<\/p>\n<p>\u8f83\u597d\u7684\u7ed3\u679c\uff0c\u5982\u679c\u80fd\u5728N<sub>2<\/sub>\u4fdd\u62a4\u4e0b\u8fdb\u884c\u6548\u679c\u5c06\u4f1a\u66f4\u597d\uff08entry 12\uff09\u3002\u4ea7\u7269<strong>4aa<\/strong>\u7684\u7edd\u5bf9\u6784\u578b\u901a\u8fc7X-\u5c04\u7ebf\u884d\u5c04\u5f97\u5230\u786e\u5b9a\uff0c\u7ed3\u679c\u8868\u660e\u5206\u5b50\u4e2d\u5b58\u5728\u4e00\u4e2a\u4e0d\u5e38\u89c1\u76842,3-\u987a\u5f0f\u7ed3\u6784\u3002<\/p>\n<p style=\"text-align: center\">\u8868 1\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/2-12.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17395 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/2-12.png\" alt=\"\" width=\"587\" height=\"603\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/2-12.png 587w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/2-12-292x300.png 292w\" sizes=\"(max-width: 587px) 100vw, 587px\" \/><\/a><\/p>\n<h4>\u4e09\u3001\u5e95\u7269\u62d3\u5c55<\/h4>\n<p>\u786e\u5b9a\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u4e4b\u540e\uff0c\u7814\u7a76\u4eba\u5458\u56fa\u5b9a\u5e95\u7269\u8089\u6842\u919b<strong>3a<\/strong>\uff0c\u9996\u5148\u63a2\u7a76\u4e86\u5e95\u72692-\u7532\u57fa-3-\u82b3\u7532\u57fa\u5432\u54da\uff08<strong>2<\/strong>\uff09\u7684\u9002\u7528\u8303\u56f4\u3002\u591a\u6570\u60c5\u51b5\u4e0b\uff0c\u5e26\u6709\u7ed9\u7535\u5b50\u57fa\u3001\u5438\u7535\u5b50\u57fa\u53d6\u4ee3\u7684\u5e95\u7269\u90fd\u80fd\u8fdb\u884c\u53cd\u5e94\uff0c\u751f\u6210\u5bf9\u5e94\u7684\u56db\u6c22\u5494\u5511\u4ea7\u7269<strong>4ba-4na<\/strong>\uff0c\u4ea7\u7387\u4e2d\u7b49\uff0838-73%\uff09\uff0c\u4f46\u662f\u5bf9\u6620\u9009\u62e9\u6027\u548c\u975e\u5bf9\u6620\u9009\u62e9\u6027\u90fd\u6781\u4f73\uff08\u56fe2\uff09\u3002\u82ef\u73af\u95f4\u4f4d\u5e26\u6709\u6c30\u57fa\u7684\u5e95\u7269<strong>2j<\/strong>\u5f97\u5230\u7684\u4ea7\u7269<em>ee<\/em>\u503c\u7565\u4f4e\u3002\u867d\u7136\u82b3\u73af\u6362\u6210\u8418\u4e4b\u540e\u4ea7\u7387\u5f88\u4f4e\uff08<strong>4ma<\/strong>\uff09\uff0c\u4f46\u975e\u5bf9\u6620\u9009\u62e9\u6027\u8fd8\u662f\u6781\u597d\u7684\uff0898%<em>ee<\/em>\uff09\u3002\u6b64\u5916\uff0c\u82b3\u6742\u73af\u4f8b\u5982\u567b\u5429\uff08<strong>4na<\/strong>\uff09\u4e5f\u53ef\u4ee5\u517c\u5bb9\u53cd\u5e94\uff0c\u4ea7\u7387\u4e2d\u7b49\u3002\u5432\u54da\u73af\u4e0a\u5e26\u6709\u4e0d\u540c\u53d6\u4ee3\u57fa\u4e5f\u53ef\u987a\u5229\u8fdb\u884c\u53cd\u5e94\uff08\u56fe3\uff09\u3002\u65e0\u8bba\u53d6\u4ee3\u57fa\u7684\u4f4d\u7f6e\u548c\u7535\u6027\u56e0\u7d20\u5982\u4f55\uff0c\u6700\u4f18\u6761\u4ef6\u4e0b\u53cd\u5e94\u90fd\u53ef\u4ee5\u987a\u5229\u8fdb\u884c\uff0c\u751f\u6210\u624b\u6027\u56db\u6c22\u5494\u5511<strong>4oa-4ua<\/strong>\uff0c\u4ea7\u7387\u4e2d\u7b49\uff0848-65%\uff09\uff0c\u4e24\u79cd\u7acb\u4f53\u9009\u62e9\u6027\u4e5f\u662f\u975e\u5e38\u597d\u7684\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/3-12.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17396 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/3-12.png\" alt=\"\" width=\"728\" height=\"584\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/3-12.png 728w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/3-12-300x241.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/3-12-680x545.png 680w\" sizes=\"(max-width: 728px) 100vw, 728px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe 2\u5e95\u72692-\u7532\u57fa-3-\u82b3\u7532\u57fa\u5432\u54da\u7684\u9002\u7528\u8303\u56f4<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/4-10.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17397 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/4-10.png\" alt=\"\" width=\"888\" height=\"419\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/4-10.png 888w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/4-10-300x142.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/4-10-768x362.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/4-10-680x321.png 680w\" sizes=\"(max-width: 888px) 100vw, 888px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe 3\u53d6\u4ee32-\u7532\u57fa-3-\u82c4\u57fa\u5432\u54da\u7684\u9002\u7528\u8303\u56f4<\/p>\n<p>\u968f\u540e\u63a2\u7a76\u7684\u662f\u03b1,\u03b2-\u4e0d\u9971\u548c\u919b\u7684\u8303\u56f4\uff0c\u03b2-\u82b3\u57fa\u6216\u6742\u73af\u82b3\u57fa\u5355\u53d6\u4ee3\u7684\u5e95\u7269\u7ed3\u679c\u5982\u4e0b\uff08\u56fe4\uff09\u3002\u4e0d\u96be\u53d1\u73b0\uff0c\u8089\u6842\u919b\u7684\u82ef\u73af\u4e0a\u4e0d\u540c\u53d6\u4ee3\u57fa\u5bf9\u53cd\u5e94\u7684\u7acb\u4f53\u9009\u62e9\u6027\u6ca1\u6709\u5927\u7684\u5f71\u54cd\uff0c\u5bf9\u5e94\u7684\u4ea7\u7269\u4e3a<strong>4ab-4ag<\/strong>\uff0c\u4ea7\u738741-66%\u3002\u567b\u5429\u73afC2\u53d6\u4ee3\u548cC3\u53d6\u4ee3\u7684\u5e95\u7269\u76f8\u6bd4\uff08<strong>4ai<\/strong><strong>\u548c<\/strong><strong>4aj<\/strong>\uff09\uff0c\u540e\u8005\u4ea7\u7387\u548c<em>ee<\/em>\u503c\u90fd\u66f4\u9ad8\uff0c\u503c\u5f97\u4e00\u63d0\u7684\u662f\u544b\u5583\u73af\u5728\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u53ef\u4ee5\u4e0e\u6c27\u5316\u5242\u5171\u5b58\uff0c\u4ea7\u7387\u53ef\u89c2\uff08<strong>4ak<\/strong>\uff09\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/5-10.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17398 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/5-10.png\" alt=\"\" width=\"898\" height=\"567\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/5-10.png 898w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/5-10-300x189.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/5-10-768x485.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/5-10-680x429.png 680w\" sizes=\"(max-width: 898px) 100vw, 898px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe 4\u5e95\u7269\u03b1,\u03b2-\u4e0d\u9971\u548c\u919b\u7684\u9002\u7528\u8303\u56f4<\/p>\n<h4>\u56db\u3001\u673a\u7406\u63a2\u7a76<\/h4>\n<p>\u4e3a\u4e86\u66f4\u5168\u9762\u5730\u7406\u89e3\u4ea7\u751f\u4e0d\u5e38\u89c12,3-\u987a\u5f0f\u4ea7\u7269\u7684\u53cd\u5e94\u8fc7\u7a0b\uff0c\u7814\u7a76\u4eba\u5458\u8fdb\u884c\u4e86\u4e24\u4e2a\u5bf9\u7167\u5b9e\u9a8c\u3002\u5728\u672c\u6587\u6c27\u5316\u53cd\u5e94\u4f53\u7cfb\u4e2d\uff0cDDQH<sub>2<\/sub>\u4f5c\u4e3a\u751f\u6210\u7684\u526f\u4ea7\u7269\u53ef\u80fd\u4f1a\u4fc3\u8fdb\u4ea7\u7269\u6784\u578b\u7684\u7ffb\u8f6c\u3002\u56e0\u800c\uff0c\u5f532,3-\u53cd\u5f0f\u7684\u919b<strong>5<\/strong>\u548cDDQH<sub>2<\/sub>\u5728\u50ac\u5316\u5242\u548c\u82ef\u7532\u9178\u5b58\u5728\u4e0b\u4ee590%\u4ea7\u7387\u751f\u6210\u4e862,3-\u987a\u5f0f\u4ea7\u7269\uff08eq 1\uff09\u3002\u6b64\u5916\uff0c\u6dfb\u52a0\u5242Pd(OAc)<sub>2<\/sub>\u5177\u6709\u7c7b\u4f3c\u7684\u8f6c\u5316\u4f5c\u7528\uff0c\u53ef\u5c06\u919b\u7684\u6784\u578b\u90e8\u5206\u8f6c\u5316\uff08\u4ea7\u738729%\uff09\uff08eq 2\uff09\u3002\u4e0a\u8ff0\u4e8b\u5b9e\u6e05\u695a\u5730\u8868\u660e\u672c\u6587\u4e0d\u5e38\u89c1\u76842,3-\u987a\u5f0f\u7ed3\u6784\u662f\u901a\u8fc7DDQH<sub>2<\/sub>\u548cPd(OAc)<sub>2<\/sub>\u5c06\u53cd\u5f0f\u7ed3\u6784\u7684\u919b\u7ffb\u8f6c\u800c\u6765\u3002\u4e3a\u4e86\u89e3\u91ca\u53cd\u5e94\u7684\u7acb\u4f53\u9009\u62e9\u6027\u7ed3\u679c\uff0c\u8bfe\u9898\u7ec4\u63d0\u51fa\u4e86\u4e00\u4e2a\u53ef\u80fd\u7684\u53cd\u5e94\u673a\u7406\uff08\u56fe6\uff09\u3002\u9996\u5148\uff0c\u5728DDQ\u4f5c\u7528\u4e0b\u5e95\u7269\u8131\u6c22\u5f62\u6210\u4e2d\u95f4\u4f53A\u3002\u4e9a\u80fa\u6b63\u79bb\u5b50B\u7531\u50ac\u5316\u5242<strong>1<\/strong>\u548cPhCO<sub>2<\/sub>H\u50ac\u5316\u5e95\u7269\u919b<strong>3a<\/strong>\u4ea7\u751f\u3002\u968f\u540e\u4e24\u4e2d\u95f4\u4f53\u987a\u5229\u5730\u53d1\u751fDiels-Alder\u53cd\u5e94\u5f97\u5230\u4e00\u4e2a\u73af\u52a0\u6210\u4e2d\u95f4\u4f53C\u3002DDQH<sub>2<\/sub>\u548cPd(OAc)<sub>2<\/sub>\u5219\u4fc3\u8fdbC3\u4f4d\u5dee\u5411\u5f02\u6784\u5316\u5f97\u52302,3-\u987a\u5f0f\u7ed3\u6784\u7684\u4e2d\u95f4\u4f53E\uff0c\u6b64\u8fc7\u7a0b\u7ecf\u5386\u624b\u6027\u70ef\u80faD\u3002\u6700\u540e\uff0c\u6c34\u89e3\u91ca\u653e\u50ac\u5316\u5242<strong>1<\/strong>\u5f97\u5230\u6700\u7ec8\u7684\u987a\u5f0f\u4ea7\u7269\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/6-9.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17399 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/6-9.png\" alt=\"\" width=\"886\" height=\"450\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/6-9.png 886w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/6-9-300x152.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/6-9-768x390.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/6-9-680x345.png 680w\" sizes=\"(max-width: 886px) 100vw, 886px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe 5\u5bf9\u7167\u5b9e\u9a8c<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/7-8.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17400 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/7-8.png\" alt=\"\" width=\"961\" height=\"585\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/7-8.png 961w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/7-8-300x183.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/7-8-768x468.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2017\/12\/7-8-680x414.png 680w\" sizes=\"(max-width: 961px) 100vw, 961px\" \/><\/a><\/p>\n<p style=\"text-align: center\">\u56fe 6\u53cd\u5e94\u673a\u7406<\/p>\n<h4>\u53c2\u8003\u6587\u732e<\/h4>\n[1]Selected recent reviews: (a) Bering, L.; Manna, S.; Antonchick, A.P. <em>Chem. &#8211; Eur. J.<\/em><strong>2017<\/strong>, 23, 10936.DOI:10.1002\/chem.201702063;(b) Qin, Y.; Zhu, L.; Luo, S.<em> Chem. Rev<\/em>. <strong>2017<\/strong>, 117, 9433. DOI:10.1021\/acs.chemrev.6b00657<\/p>\n[2]Selected reviews on the CDC reaction: (a) Li, C.-J. <em>Acc. Chem. Res<\/em>. <strong>2009<\/strong>, 42, 335.\u00a0DOI:10.1021\/ar800164n (b) Scheuermann, C. J. <em>Chem. &#8211; Asian J<\/em>.<strong> 2010<\/strong>, 5,436.\u00a0DOI:10.1002\/asia.200900487<\/p>\n[3]Li, W.; Zhou, L.; Zhang, J. <em>Chem. &#8211; Eur. J<\/em>. <strong>2016<\/strong>, 22, 1558. DOI:10.1002\/chem.201503571<\/p>\n[4]Stang, E. M.; White, M. C. <em>J. Am. Chem. Soc.\u00a0<\/em><strong>2011<\/strong>, 133, 14892. DOI: 10.1021\/ja2059704<\/p>\n[5]Manna, S.; Antonchick, A. P. <em>Chem. &#8211; Eur. J.\u00a0<\/em><strong>2017<\/strong>, 23, 7825. DOI: 10.1002\/chem.201701535<\/p>\n[6](a) Zhou, L.; Xu, B.; Zhang, <em>J. Angew. Chem., Int. Ed<\/em>. <strong>2015<\/strong>, 54,9092.\u00a0DOI: 10.1002\/anie.201503549 (b) Liu, T. X.; Ma, J. L.; Chao, D.; Zhang, P. L.; Ma, N. N.; Liu,Q. F.; Shi, L.; Zhang, Z. G.; Zhang, G. S. <em>Org. Lett. <\/em><strong>2016<\/strong>, 18, 4044. DOI: 10.1021\/acs.orglett.6b01902<\/p>\n<p>&nbsp;<\/p>\n<p>\u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01 <\/p>\n","protected":false},"excerpt":{"rendered":"\u6458\u8981 \u5408\u80a5\u5de5\u4e1a\u5927\u5b66\u5434\u7965\u8bfe\u9898\u7ec4\uff08\u4e3b\u9875\uff09\u8fd1\u65e5\u53d1\u5c55\u4e86\u4e00\u79cd\u65b0\u9896\u7684\u4e0d\u5bf9\u79f0\u8131\u6c22Diels-Alder\u53cd\u5e94\u3002\u8be5\u53cd\u5e94\u5e95\u7269\u8303\u56f4\u5e7f\uff0c\u7acb\u4f53\u9009\u62e9\u6027\u9ad8\uff0c\u53ef\u4e3a\u5176\u4ed6\u73cd\u8d35\u624b\u6027\u5316\u5408\u7269\u7684\u5408\u6210\u63d0\u4f9b\u53c2\u8003\u3002 An Asymmetric Dehydrogenative Diels\u2013Alder Reaction for the Synthesis of Chiral Tetrahydrocarbazole Derivatives Xiang Wu* , Hai-Jie Zhu, Shi-Bao Zhao, Shu-Sen Chen, Yun-Fei Luo, and You-Gui Li Org. Lett., 2018, 20, 32\u201335.\u00a0DOI\uff1a10.1021\/acs.orglett.7b03251 \u5bfc\u5e08\u7b80\u4ecb\uff08\u5f15\u7528\u81ea\u5408\u80a5\u5de5\u4e1a\u5927\u5b66\u5b98\u7f51\uff09 \u5434\u7965 2001.09-2005.06\uff0c\u5357\u5f00\u5927\u5b66\u5316\u5b66\u5b66\u9662\uff0c\u7406\u79d1\u57fa\u5730\u73ed\uff0c\u672c\u79d1 2005.09-2010.12\uff0c\u5357\u5f00\u5927\u5b66\u5143\u7d20\u6709\u673a\u56fd\u5bb6\u91cd\u70b9\u5b9e\u9a8c\u5ba4\uff0c\u535a\u58eb 2010.12-2012.08\uff0c\u82cf\u5dde\u8bfa\u534e\u5236\u836f\u79d1\u6280\u6709\u9650\u516c\u53f8\uff0c\u9ad8\u7ea7\u7814\u7a76\u5458 2012.08-2014.12\uff0c\u4e2d\u56fd\u79d1\u5b66\u6280\u672f\u5927\u5b66\u5fae\u5c3a\u5ea6\u7269\u8d28\u79d1\u5b66\u56fd\u5bb6\u5b9e\u9a8c\u5ba4\uff0c\u535a\u58eb\u540e 2014.12-2015.08\uff0c\u7f8e\u56fd\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5dde\u7acb\u5927\u5b66\u5316\u5b66\u7cfb\uff0c\u535a\u58eb\u540e 2015.08-\u81f3\u4eca\uff0c\u5408\u80a5\u5de5\u4e1a\u5927\u5b66\u5316\u5b66\u4e0e\u5316\u5de5\u5b66\u9662\u5e94\u7528\u5316\u5b66\u7cfb\uff0c\u526f\u7814\u7a76\u5458 &nbsp; \u4e00\u3001\u7814\u7a76\u80cc\u666f C-H\u952e\u7684\u76f4\u63a5\u5b98\u80fd\u56e2\u5316\u662f\u901a\u8fc7\u6613\u5f97\u539f\u6599\u5408\u6210\u590d\u6742\u5206\u5b50\u7684\u4e00\u79cd\u5f3a\u6709\u529b\u7684\u65b9\u6cd5[1]\u3002\u4e24\u4e2aC-H\u952e\u7684\u4ea4\u53c9\u8131\u6c22\u5076\u8054\uff08cross dehydrogenative coupling\uff0cCDC\uff09\u662f\u9ad8\u6548\u6784\u5efaC-C\u952e\u7684\u53e6\u4e00\u7b56\u7565[2]\u3002\u5c24\u5176\u8981\u63d0\u7684\u662f\uff0c\u8131\u6c22\u540e\u4ea7\u751f\u7684\u591a\u79cd\u591a\u6837\u7684\u53cc\u70ef\u7528\u4e8eDiels-Alder\u53cd\u5e94\u5df2\u7ecf\u6210\u4e3a\u4e00\u6b65\u6784\u5efa\u516d\u5143\u78b3\u73af\u7684\u72ec\u7279\u65b9\u6cd5[3]\u30022011\u5e74White\u7b49\u4eba\u62a5\u9053\u4e86Pd\u50ac\u5316\u4e0b\u672b\u7aef\u70ef\u70c3\u70ef\u4e19\u4f4dC-H\u952e\u8131\u6c22\u6c27\u5316\u5f62\u6210\u53cc\u70ef\u7684\u65b9\u6cd5[4]\u3002\u53cc\u70ef\u548c\u70ef\u916e\u7684Diels-Alder\u53cd\u5e94\u4e5f\u4f7fBrosimonesA\u548cB\u7684\u5168\u5408\u6210\u5f97\u4ee5\u5b9e\u73b0\u3002\u6700\u8fd1\uff0cAntonchick\u7ec4\u6210\u529f\u5730\u5c06\u53cc\u70ef\u524d\u4f53\u8303\u56f4\u6269\u5c55\u5230\u7b80\u5355\u7684\u82b3\u70f7\u70c3\uff0c\u591a\u79cd\u7f3a\u7535\u5b50\u7684\u70ef\u70c3\u4f5c\u4e3a\u4eb2\u53cc\u70ef\u4f53\u53c2\u4e0e\u6b64Diels-Alder\u53cd\u5e94[5]\u3002 \u4f5c\u4e3a\u4e00\u4e2a\u72ec\u7279\u7684\u7ed3\u6784\u6a21\u5757\uff0c\u56db\u6c22\u5494\u5511\u5305\u542b\u591a\u4e2a\u7acb\u4f53\u4e2d\u5fc3\uff0c\u5e7f\u6cdb\u5b58\u5728\u4e8e\u5929\u7136\u7684\u5432\u54da\u751f\u7269\u78b1\u548c\u5408\u6210\u836f\u7269\uff0c\u5b83\u4eec\u5177\u6709\u591a\u79cd\u91cd\u8981\u7684\u751f\u7269\u6d3b\u6027\uff08\u56fe1\uff0cB\uff09\u3002\u629b\u5f00\u5408\u6210\u56db\u6c22\u5494\u5511\u884d\u751f\u7269\u53d6\u5f97\u7684\u8fdb\u6b65\uff0c\u65b0\u9896\u548c\u66f4\u52a0\u9ad8\u6548\u5730\u5408\u6210\u591a\u6837\u5316\u56db\u6c22\u5494\u5511\u7ed3\u6784\u7684\u65b9\u6cd5\u5728\u6709\u673a\u548c\u533b\u836f\u5316\u5b66\u9886\u57df\u4ecd\u7136\u8feb\u5207\u9700\u8981\u3002\u8131\u6c22Diels-Alder\u53cd\u5e94\u5df2\u7ecf\u88ab\u7528\u4e8e\u56db\u6c22\u5494\u5511\u7684\u5408\u6210\uff0cZhang\u7b49\u4eba\u53d1\u73b0DDQ\u4fc3\u8fdb2-\u7532\u57fa-3-\u82b3\u7532\u57fa\u548c\u4eb2\u53cc\u70ef\u4f53\u7684Diels-Alder\u53cd\u5e94\u7ecf\u5386\u7684\u662findole-2,3-quinodimethane\u9014\u5f84\uff08\u56fe1\uff0cA\uff09[6]\u3002\u8bfe\u9898\u7ec4\u7684\u5174\u8da3\u662f\u4e0d\u5bf9\u79f0\u6c27\u5316C-H\u952e\u5b98\u80fd\u56e2\u5316\uff0c\u56e0\u6b64\u4ed6\u4eec\u5e0c\u671b\u5b9e\u73b0\u6b64\u53cd\u5e94\u7684\u5bf9\u6620\u9009\u62e9\u6027\u3002\u6c27\u5316\u6cd5\u6784\u5efa\u624b\u6027\u56db\u6c22\u5494\u5511\u6ca1\u6709\u5148\u4f8b\u4e3b\u8981\u539f\u56e0\u53ef\u80fd\u662f\uff081\uff09\u6c27\u5316\u5242\u4e0e\u624b\u6027\u50ac\u5316\u5242\u4e4b\u95f4\u7684\u517c\u5bb9\u95ee\u9898\uff1b\uff082\uff09\u8fc7\uff08\u5ea6\uff09\u6c27\u5316\u95ee\u9898\u3002\u56e0\u6b64\uff0c\u672c\u6587\u62a5\u9053\u4e862-\u7532\u57fa-3-\u82b3\u7532\u57fa\u5432\u54da\u548c\u03b1,\u03b2-\u4e0d\u9971\u548c\u919b\u7684\u9996\u4f8b\u4e0d\u5bf9\u79f0\u8131\u6c22Diels-Alder\u53cd\u5e94\uff08\u56fe1\uff0cC\uff09\u3002\u901a\u8fc7\u624b\u6027\u4e8c\u7ea7\u80fa\u50ac\u5316\u5242\u964d\u4f4e\u4e0d\u9971\u548c\u919bLUMO\u8f68\u9053\u80fd\u91cf\u8fd9\u79cd\u7ecf\u5178\u7684\u6d3b\u5316\u65b9\u5f0f\uff0c\u6b64\u53cd\u5e94\u53ef\u4ee5\u5b9e\u73b0\u6781\u597d\u7684\u7acb\u4f53\u63a7\u5236\uff0c\u5f97\u5230\u5e26\u6709\u4e09\u4e2a\u76f8\u90bb\u624b\u6027\u4e2d\u5fc3\u7684\u5149\u5b66\u7eaf\u7684\u56db\u6c22\u5494\u5511\u3002 \u56fe 1\u5408\u6210\u56db\u6c22\u5494\u5511\u7684\u8131\u6c22Diels-Alder\u53cd\u5e94 \u4e8c\u3001\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316 \u8bfe\u9898\u7ec4\u4eba\u5458\u57284\u00c5MS\u5b58\u5728\u4e0b\uff0c\u4ee53-\u82c4\u57fa-2-\u7532\u57fa-1H-\u5432\u54da\uff082a\uff09\u548c\u8089\u6842\u919b\uff083a\uff09\u4e3a\u5e95\u7269\uff0cDDQ\u4f5c\u4e3a\u6c27\u5316\u5242\uff0c\u03b1,\u03b1-\u4e8c\u82ef\u57fa\u812f\u6c28\u9178\u4e09\u7532\u57fa\u7845\u919a\uff081\uff09\/\u82ef\u7532\u9178\u4f5c\u4e3a\u50ac\u5316\u5242\u5efa\u7acb\u6a21\u578b\u53cd\u5e94\u300250\u2103\u4e0b\uff0cCHCl3\u4e2d\u8fdb\u884c\u7684\u53cd\u5e94\u53d6\u5f97\u8f83\u4e3a\u4e0d\u9519\u7684\u7ed3\u679c\uff0cNaBH4\u8fd8\u539f\u4e4b\u540e\u89c2\u5bdf\u52303:1\u7684dr\u503c\uff0c\u4e3b\u8981\u7684\u975e\u5bf9\u6620\u4f534aa\u5206\u79bb\u4ea7\u738757%\uff0cee\u503c\u9ad8\u8fbe99%\uff0c\u4ec5\u6709\u5c11\u91cf\u7684\u6c27\u5316\u526f\u4ea7\u72693-\u82ef\u7532\u9170\u57fa-2-\u7532\u57fa-1H-\u5432\u54da\u751f\u6210\uff08\u88681\uff0centry 1\uff09\u3002\u6539\u53d8\u4e0d\u540c\u7684Br\u00f8nsted\u9178\uff0c\u4ea7\u7387\u964d\u4f4e\uff08entries 2-4\uff09\u3002\u503c\u5f97\u63d0\u51fa\u7684\u662f\u4e00\u4e2a\u5f3a\u7684Br\u00f8nsted\u9178\u4f1a\u63d0\u9ad8\u53cd\u5e94\u7684\u975e\u5bf9\u6620\u9009\u62e9\u6027\uff08entries 2,4 vs 1\uff09\u3002\u7b5b\u9009\u6eb6\u5242\u65f6\u53d1\u73b0\uff0c\u5728DCE\u3001THF\u3001\u7532\u82ef\u548cDMSO\u4e2d\uff0cCHCl3\u4ecd\u7136\u662f\u6700\u597d\u7684\u6eb6\u5242\uff08entries 5-8 vs 1\uff09\u3002\u4e3a\u4e86\u63d0\u9ad8\u975e\u5bf9\u6620\u9009\u62e9\u6027\uff0c\u8bfe\u9898\u7ec4\u4eba\u5458\u63a2\u7a76\u4e86\u6dfb\u52a0\u5242\u7684\u4f5c\u7528\uff0c\u50ac\u5316\u91cf\u7684\u8fc7\u6e21\u91d1\u5c5e\u76d0\u786e\u5b9e\u63d0\u9ad8\u4e86dr\u503c\uff08entries 9-12\uff09\u3002\u4f8b\u5982\uff0c\u52a0\u516520 mol%\u7684CuCl2\u6216NiCl2\u4f1a\u5f97\u5230\u5927\u4e8e10:1\u7684dr\u503c\uff0c\u7136\u800c\u662f\u4ee5\u964d\u4f4e\u5bf9\u6620\u9009\u62e9\u6027\u4e3a\u4ee3\u4ef7\u7684\uff08entries 9-10\uff09\u3002Pd(OAc)2\u5728\u975e\u5bf9\u6620\u9009\u62e9\u6027\u548c\u5bf9\u6620\u9009\u62e9\u6027\u4e0a\u90fd\u80fd\u53d6\u5f97 \u8f83\u597d\u7684\u7ed3\u679c\uff0c\u5982\u679c\u80fd\u5728N2\u4fdd\u62a4\u4e0b\u8fdb\u884c\u6548\u679c\u5c06\u4f1a\u66f4\u597d\uff08entry 12\uff09\u3002\u4ea7\u72694aa\u7684\u7edd\u5bf9\u6784\u578b\u901a\u8fc7X-\u5c04\u7ebf\u884d\u5c04\u5f97\u5230\u786e\u5b9a\uff0c\u7ed3\u679c\u8868\u660e\u5206\u5b50\u4e2d\u5b58\u5728\u4e00\u4e2a\u4e0d\u5e38\u89c1\u76842,3-\u987a\u5f0f\u7ed3\u6784\u3002 \u8868 1\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316 \u4e09\u3001\u5e95\u7269\u62d3\u5c55 \u786e\u5b9a\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u4e4b\u540e\uff0c\u7814\u7a76\u4eba\u5458\u56fa\u5b9a\u5e95\u7269\u8089\u6842\u919b3a\uff0c\u9996\u5148\u63a2\u7a76\u4e86\u5e95\u72692-\u7532\u57fa-3-\u82b3\u7532\u57fa\u5432\u54da\uff082\uff09\u7684\u9002\u7528\u8303\u56f4\u3002\u591a\u6570\u60c5\u51b5\u4e0b\uff0c\u5e26\u6709\u7ed9\u7535\u5b50\u57fa\u3001\u5438\u7535\u5b50\u57fa\u53d6\u4ee3\u7684\u5e95\u7269\u90fd\u80fd\u8fdb\u884c\u53cd\u5e94\uff0c\u751f\u6210\u5bf9\u5e94\u7684\u56db\u6c22\u5494\u5511\u4ea7\u72694ba-4na\uff0c\u4ea7\u7387\u4e2d\u7b49\uff0838-73%\uff09\uff0c\u4f46\u662f\u5bf9\u6620\u9009\u62e9\u6027\u548c\u975e\u5bf9\u6620\u9009\u62e9\u6027\u90fd\u6781\u4f73\uff08\u56fe2\uff09\u3002\u82ef\u73af\u95f4\u4f4d\u5e26\u6709\u6c30\u57fa\u7684\u5e95\u72692j\u5f97\u5230\u7684\u4ea7\u7269ee\u503c\u7565\u4f4e\u3002\u867d\u7136\u82b3\u73af\u6362\u6210\u8418\u4e4b\u540e\u4ea7\u7387\u5f88\u4f4e\uff084ma\uff09\uff0c\u4f46\u975e\u5bf9\u6620\u9009\u62e9\u6027\u8fd8\u662f\u6781\u597d\u7684\uff0898%ee\uff09\u3002\u6b64\u5916\uff0c\u82b3\u6742\u73af\u4f8b\u5982\u567b\u5429\uff084na\uff09\u4e5f\u53ef\u4ee5\u517c\u5bb9\u53cd\u5e94\uff0c\u4ea7\u7387\u4e2d\u7b49\u3002\u5432\u54da\u73af\u4e0a\u5e26\u6709\u4e0d\u540c\u53d6\u4ee3\u57fa\u4e5f\u53ef\u987a\u5229\u8fdb\u884c\u53cd\u5e94\uff08\u56fe3\uff09\u3002\u65e0\u8bba\u53d6\u4ee3\u57fa\u7684\u4f4d\u7f6e\u548c\u7535\u6027\u56e0\u7d20\u5982\u4f55\uff0c\u6700\u4f18\u6761\u4ef6\u4e0b\u53cd\u5e94\u90fd\u53ef\u4ee5\u987a\u5229\u8fdb\u884c\uff0c\u751f\u6210\u624b\u6027\u56db\u6c22\u5494\u55114oa-4ua\uff0c\u4ea7\u7387\u4e2d\u7b49\uff0848-65%\uff09\uff0c\u4e24\u79cd\u7acb\u4f53\u9009\u62e9\u6027\u4e5f\u662f\u975e\u5e38\u597d\u7684\u3002 \u56fe 2\u5e95\u72692-\u7532\u57fa-3-\u82b3\u7532\u57fa\u5432\u54da\u7684\u9002\u7528\u8303\u56f4 \u56fe 3\u53d6\u4ee32-\u7532\u57fa-3-\u82c4\u57fa\u5432\u54da\u7684\u9002\u7528\u8303\u56f4 \u968f\u540e\u63a2\u7a76\u7684\u662f\u03b1,\u03b2-\u4e0d\u9971\u548c\u919b\u7684\u8303\u56f4\uff0c\u03b2-\u82b3\u57fa\u6216\u6742\u73af\u82b3\u57fa\u5355\u53d6\u4ee3\u7684\u5e95\u7269\u7ed3\u679c\u5982\u4e0b\uff08\u56fe4\uff09\u3002\u4e0d\u96be\u53d1\u73b0\uff0c\u8089\u6842\u919b\u7684\u82ef\u73af\u4e0a\u4e0d\u540c\u53d6\u4ee3\u57fa\u5bf9\u53cd\u5e94\u7684\u7acb\u4f53\u9009\u62e9\u6027\u6ca1\u6709\u5927\u7684\u5f71\u54cd\uff0c\u5bf9\u5e94\u7684\u4ea7\u7269\u4e3a4ab-4ag\uff0c\u4ea7\u738741-66%\u3002\u567b\u5429\u73afC2\u53d6\u4ee3\u548cC3\u53d6\u4ee3\u7684\u5e95\u7269\u76f8\u6bd4\uff084ai\u548c4aj\uff09\uff0c\u540e\u8005\u4ea7\u7387\u548cee\u503c\u90fd\u66f4\u9ad8\uff0c\u503c\u5f97\u4e00\u63d0\u7684\u662f\u544b\u5583\u73af\u5728\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u53ef\u4ee5\u4e0e\u6c27\u5316\u5242\u5171\u5b58\uff0c\u4ea7\u7387\u53ef\u89c2\uff084ak\uff09\u3002 \u56fe 4\u5e95\u7269\u03b1,\u03b2-\u4e0d\u9971\u548c\u919b\u7684\u9002\u7528\u8303\u56f4 \u56db\u3001\u673a\u7406\u63a2\u7a76 \u4e3a\u4e86\u66f4\u5168\u9762\u5730\u7406\u89e3\u4ea7\u751f\u4e0d\u5e38\u89c12,3-\u987a\u5f0f\u4ea7\u7269\u7684\u53cd\u5e94\u8fc7\u7a0b\uff0c\u7814\u7a76\u4eba\u5458\u8fdb\u884c\u4e86\u4e24\u4e2a\u5bf9\u7167\u5b9e\u9a8c\u3002\u5728\u672c\u6587\u6c27\u5316\u53cd\u5e94\u4f53\u7cfb\u4e2d\uff0cDDQH2\u4f5c\u4e3a\u751f\u6210\u7684\u526f\u4ea7\u7269\u53ef\u80fd\u4f1a\u4fc3\u8fdb\u4ea7\u7269\u6784\u578b\u7684\u7ffb\u8f6c\u3002\u56e0\u800c\uff0c\u5f532,3-\u53cd\u5f0f\u7684\u919b5\u548cDDQH2\u5728\u50ac\u5316\u5242\u548c\u82ef\u7532\u9178\u5b58\u5728\u4e0b\u4ee590%\u4ea7\u7387\u751f\u6210\u4e862,3-\u987a\u5f0f\u4ea7\u7269\uff08eq 1\uff09\u3002\u6b64\u5916\uff0c\u6dfb\u52a0\u5242Pd(OAc)2\u5177\u6709\u7c7b\u4f3c\u7684\u8f6c\u5316\u4f5c\u7528\uff0c\u53ef\u5c06\u919b\u7684\u6784\u578b\u90e8\u5206\u8f6c\u5316\uff08\u4ea7\u738729%\uff09\uff08eq 2\uff09\u3002\u4e0a\u8ff0\u4e8b\u5b9e\u6e05\u695a\u5730\u8868\u660e\u672c\u6587\u4e0d\u5e38\u89c1\u76842,3-\u987a\u5f0f\u7ed3\u6784\u662f\u901a\u8fc7DDQH2\u548cPd(OAc)2\u5c06\u53cd\u5f0f\u7ed3\u6784\u7684\u919b\u7ffb\u8f6c\u800c\u6765\u3002\u4e3a\u4e86\u89e3\u91ca\u53cd\u5e94\u7684\u7acb\u4f53\u9009\u62e9\u6027\u7ed3\u679c\uff0c\u8bfe\u9898\u7ec4\u63d0\u51fa\u4e86\u4e00\u4e2a\u53ef\u80fd\u7684\u53cd\u5e94\u673a\u7406\uff08\u56fe6\uff09\u3002\u9996\u5148\uff0c\u5728DDQ\u4f5c\u7528\u4e0b\u5e95\u7269\u8131\u6c22\u5f62\u6210\u4e2d\u95f4\u4f53A\u3002\u4e9a\u80fa\u6b63\u79bb\u5b50B\u7531\u50ac\u5316\u52421\u548cPhCO2H\u50ac\u5316\u5e95\u7269\u919b3a\u4ea7\u751f\u3002\u968f\u540e\u4e24\u4e2d\u95f4\u4f53\u987a\u5229\u5730\u53d1\u751fDiels-Alder\u53cd\u5e94\u5f97\u5230\u4e00\u4e2a\u73af\u52a0\u6210\u4e2d\u95f4\u4f53C\u3002DDQH2\u548cPd(OAc)2\u5219\u4fc3\u8fdbC3\u4f4d\u5dee\u5411\u5f02\u6784\u5316\u5f97\u52302,3-\u987a\u5f0f\u7ed3\u6784\u7684\u4e2d\u95f4\u4f53E\uff0c\u6b64\u8fc7\u7a0b\u7ecf\u5386\u624b\u6027\u70ef\u80faD\u3002\u6700\u540e\uff0c\u6c34\u89e3\u91ca\u653e\u50ac\u5316\u52421\u5f97\u5230\u6700\u7ec8\u7684\u987a\u5f0f\u4ea7\u7269\u3002 \u56fe 5\u5bf9\u7167\u5b9e\u9a8c \u56fe 6\u53cd\u5e94\u673a\u7406 \u53c2\u8003\u6587\u732e [1]Selected recent reviews: (a) Bering, L.; Manna, S.; Antonchick, A.P. Chem. &#8211; Eur. J.2017, 23, 10936.DOI:10.1002\/chem.201702063;(b) Qin, Y.; Zhu, L.; Luo, S. Chem. Rev. 2017, 117, [&hellip;]","protected":false},"author":22,"featured_media":17644,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1271],"tags":[1766,2178],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/Org-Lett.jpg","jetpack_shortlink":"https:\/\/wp.me\/p96op1-4wx","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/17393"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/22"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=17393"}],"version-history":[{"count":10,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/17393\/revisions"}],"predecessor-version":[{"id":27209,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/17393\/revisions\/27209"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/17644"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=17393"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=17393"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=17393"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}