{"id":17621,"date":"2018-01-30T06:17:20","date_gmt":"2018-01-29T22:17:20","guid":{"rendered":"\/\/www.gsbet888.com\/?p=17621"},"modified":"2019-08-02T18:52:04","modified_gmt":"2019-08-02T10:52:04","slug":"%e5%85%b0%e5%a0%a1-%e5%b7%b4%e5%85%8b%e4%bc%a6%e5%8f%8d%e5%ba%94-ramberg-backlund-rearrangement","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/reactions\/2018\/01\/%e5%85%b0%e5%a0%a1-%e5%b7%b4%e5%85%8b%e4%bc%a6%e5%8f%8d%e5%ba%94-ramberg-backlund-rearrangement.html","title":{"rendered":"\u5170\u5821\u2013\u5df4\u514b\u4f26\u53cd\u5e94 Ramberg-Backlund Rearrangement"},"content":{"rendered":"<h4>\u6982\u8981<\/h4>\n<p>\u5f53\u03b1-\u5364\u4ee3\u781c\u7528\u78b1\u5904\u7406\u65f6\uff0c\u4f34\u968f\u7740C-C\u952e\u7684\u5f62\u6210\u30fb\u4e8c\u6c27\u5316\u786b\u7684\u79bb\u53bb\uff0c\u5f97\u5230\u70ef\u70c3\u4ea7\u7269\u3002\u8be5\u65b9\u6cd5\u662f\u95f4\u63a5\u7684\u78b3 &#8211; \u78b3\u952e\u5f62\u6210\u53cd\u5e94\u4e4b\u4e00\u3002<\/p>\n<p>&nbsp;<\/p>\n<h4>\u5173\u8054\u53cd\u5e94\uff08\u672c\u7f51\u7ad9\uff09<\/h4>\n<ul class=\"list\">\n<li><a href=\"\/\/www.gsbet888.com\/reactions\/%e7%8e%af%e5%8c%96%e5%8f%8d%e5%ba%94\/2015\/05\/%e8%9e%af%e5%8f%98%e5%8f%8d%e5%ba%94cheletropic-reaction-2.html\">Cheletropic Reaction\u00a0<\/a><\/li>\n<li><a href=\"\/\/www.gsbet888.com\/reactions\/2014\/10\/post-2814.html\">Organolithium Reagents<\/a><\/li>\n<li><a href=\"\/\/www.gsbet888.com\/reactions\/%e9%87%8d%e6%8e%92%e5%8f%8d%e5%ba%94\/2014\/06\/%e6%b3%95%e6%b2%83%e5%b0%94%e6%96%af%e5%9f%ba%e9%87%8d%e6%8e%92%e5%8f%8d%e5%ba%94-favorskii-rearrangement.html\">Favorskii Rearrangement<\/a><\/li>\n<li><a href=\"\/\/www.gsbet888.com\/reactions\/2014\/04\/post-940.html\">Julia-Lythgoe Olefination<\/a><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4>\u57fa\u672c\u6587\u732e<\/h4>\n<ul>\n<li>Ramberg, L.; Backlund B. <em>Arkiv Kemi, Minerat. Geol.\u00a0<\/em><strong>1940<\/strong>, <em>13A<\/em>, 50.<\/li>\n<li>Paquett, L. A. <em>Acc. Chem. Res.<\/em> <strong>1968<\/strong>, <em>1<\/em>,\u00a0209. DOI: <a href=\"http:\/\/dx.doi.org\/10.1021\/ar50007a003\">10.1021\/ar50007a003<\/a><\/li>\n<li>Paquett, L. A. <em>Org. React.<\/em> <strong>1977<\/strong>, <em>25<\/em>,\u00a01. doi:<a href=\"http:\/\/dx.doi.org\/10.1002\/0471264180.or025.01\">10.1002\/0471264180.or025.01<\/a><\/li>\n<li>Hartman, G. D.; Hartman, R. D. <em>Synthesis<\/em> <strong>1982<\/strong>,\u00a0504.<\/li>\n<li>Clough, J. M. <em>Comprehensive Organic Synthesis<\/em> <strong>1991<\/strong>,\u00a0<em>3<\/em>, 861.<\/li>\n<li>Taylor, R. J. K. <em>Chem. Commun.<\/em> <strong>1999<\/strong>, 217.\u00a0DOI: <a href=\"http:\/\/dx.doi.org\/10.1039\/a806615i%20\">10.1039\/a806615i<br \/>\n<\/a><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4>\u53cd\u5e94\u673a\u7406<\/h4>\n<p>\u781c\u7684\u03b1\u4f4d\u7684\u6c22\u7684\u9178\u6027\u6bd4\u8f83\u9ad8\uff0c\u56e0\u6b64\u6bd4\u8f83\u5bb9\u6613\u88ab\u78b1\u62d4\u53bb\u3002\u7ee7\u800c\u53d1\u751f\u5206\u5b50\u5185\u4eb2\u6838\u53cd\u5e94\u5f62\u6210 thiirane dioxide intermediate\uff0c\u6700\u540e\u79bb\u53bbSO<sub>2<\/sub>\u751f\u6210\u78b3-\u78b3\u53cc\u952e\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17622 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/ramberg_backlund_2.gif\" alt=\"\" width=\"582\" height=\"85\" \/><\/p>\n<h4>\u53cd\u5e94\u5b9e\u4f8b<\/h4>\n<p>\u901a\u8fc7\u4e59\u70ef\u781c\u7684\u5171\u8f6d\u52a0\u6210\u4ea7\u751f\u78b3\u8d1f\u79bb\u5b50\uff0c\u7ee7\u800c\u53d1\u751f\u4e00\u7cfb\u5217\u5982\u4e0b\u56fe\u6240\u793a\u7684\u4e32\u8054\u53cd\u5e94\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17623 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/ramberg_backlund_3.gif\" alt=\"\" width=\"411\" height=\"141\" \/><\/p>\n<p>\u4e0e\u73af\u4e19\u70f7\u7684\u5f00\u73af\u53cd\u5e94\u7ec4\u5408\u7684\u5b9e\u4f8b[2]\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-17624 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/ramberg_backlund_4.gif\" alt=\"\" width=\"558\" height=\"64\" \/><\/p>\n<h4>\u5b9e\u9a8c\u6b65\u9aa4<\/h4>\n<p>&nbsp;<\/p>\n<h4>\u5b9e\u9a8c\u6280\u5de7<\/h4>\n<p>&nbsp;<\/p>\n<h4>\u53c2\u8003\u6587\u732e<\/h4>\n[1] Burger, J. J.; Chen, T. B. R. A. ; de Waard, E. R.; Huisman,\u00a0H. O. <em>Tetrahedron<\/em><strong>1981<\/strong>, <em>37<\/em>, 417.\u00a0doi:<a href=\"http:\/\/dx.doi.org\/10.1016\/S0040-4020%2801%2992030-7%20\">10.1016\/S0040-4020(01)92030-7<\/a>[2] (a) Evans, P.; Taylor, R. J. K. <em>Tetrahedron Lett.<\/em> <strong>1997<\/strong>,\u00a0<em>38<\/em>, 3055. doi:<a href=\"http:\/\/dx.doi.org\/10.1016\/S0040-4039%2897%2900507-8\">10.1016\/S0040-4039(97)00507-8<\/a>\u00a0(b) Evans, P.; Johnson, P.; Taylor, R. J. K. <em>Eur. J. Org. Chem.\u00a0<\/em><strong>2006<\/strong>, 1740.doi: <a href=\"http:\/\/dx.doi.org\/10.1002\/ejoc.200500956\">10.1002\/ejoc.200500956<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>\u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01 <\/p>\n","protected":false},"excerpt":{"rendered":"\u6982\u8981 \u5f53\u03b1-\u5364\u4ee3\u781c\u7528\u78b1\u5904\u7406\u65f6\uff0c\u4f34\u968f\u7740C-C\u952e\u7684\u5f62\u6210\u30fb\u4e8c\u6c27\u5316\u786b\u7684\u79bb\u53bb\uff0c\u5f97\u5230\u70ef\u70c3\u4ea7\u7269\u3002\u8be5\u65b9\u6cd5\u662f\u95f4\u63a5\u7684\u78b3 &#8211; \u78b3\u952e\u5f62\u6210\u53cd\u5e94\u4e4b\u4e00\u3002 &nbsp; \u5173\u8054\u53cd\u5e94\uff08\u672c\u7f51\u7ad9\uff09 Cheletropic Reaction\u00a0 Organolithium Reagents Favorskii Rearrangement Julia-Lythgoe Olefination &nbsp; \u57fa\u672c\u6587\u732e Ramberg, L.; Backlund B. Arkiv Kemi, Minerat. Geol.\u00a01940, 13A, 50. Paquett, L. A. Acc. Chem. Res. 1968, 1,\u00a0209. DOI: 10.1021\/ar50007a003 Paquett, L. A. Org. React. 1977, 25,\u00a01. doi:10.1002\/0471264180.or025.01 Hartman, G. D.; Hartman, R. D. Synthesis 1982,\u00a0504. Clough, J. M. Comprehensive Organic Synthesis 1991,\u00a03, 861. Taylor, R. J. K. Chem. Commun. 1999, 217.\u00a0DOI: 10.1039\/a806615i &nbsp; \u53cd\u5e94\u673a\u7406 \u781c\u7684\u03b1\u4f4d\u7684\u6c22\u7684\u9178\u6027\u6bd4\u8f83\u9ad8\uff0c\u56e0\u6b64\u6bd4\u8f83\u5bb9\u6613\u88ab\u78b1\u62d4\u53bb\u3002\u7ee7\u800c\u53d1\u751f\u5206\u5b50\u5185\u4eb2\u6838\u53cd\u5e94\u5f62\u6210 thiirane dioxide intermediate\uff0c\u6700\u540e\u79bb\u53bbSO2\u751f\u6210\u78b3-\u78b3\u53cc\u952e\u3002 \u53cd\u5e94\u5b9e\u4f8b \u901a\u8fc7\u4e59\u70ef\u781c\u7684\u5171\u8f6d\u52a0\u6210\u4ea7\u751f\u78b3\u8d1f\u79bb\u5b50\uff0c\u7ee7\u800c\u53d1\u751f\u4e00\u7cfb\u5217\u5982\u4e0b\u56fe\u6240\u793a\u7684\u4e32\u8054\u53cd\u5e94\u3002 \u4e0e\u73af\u4e19\u70f7\u7684\u5f00\u73af\u53cd\u5e94\u7ec4\u5408\u7684\u5b9e\u4f8b[2] \u5b9e\u9a8c\u6b65\u9aa4 &nbsp; \u5b9e\u9a8c\u6280\u5de7 &nbsp; \u53c2\u8003\u6587\u732e [1] Burger, J. J.; Chen, T. B. R. A. ; de Waard, E. R.; Huisman,\u00a0H. O. Tetrahedron1981, 37, 417.\u00a0doi:10.1016\/S0040-4020(01)92030-7[2] (a) Evans, P.; Taylor, R. J. K. Tetrahedron [&hellip;]","protected":false},"author":5,"featured_media":17630,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2],"tags":[2175,2174,716],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/01\/2014-10-29_22-42-11.png","jetpack_shortlink":"https:\/\/wp.me\/p96op1-4Ad","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/17621"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=17621"}],"version-history":[{"count":7,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/17621\/revisions"}],"predecessor-version":[{"id":27190,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/17621\/revisions\/27190"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/17630"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=17621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=17621"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=17621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}