{"id":19195,"date":"2018-07-09T10:13:30","date_gmt":"2018-07-09T02:13:30","guid":{"rendered":"\/\/www.gsbet888.com\/?p=19195"},"modified":"2019-08-02T18:51:35","modified_gmt":"2019-08-02T10:51:35","slug":"%e5%8f%af%e4%bb%a5%e6%97%a0%e9%99%90%e7%8e%a9%e8%8a%b1%e7%9a%84aldol%e7%bc%a9%e5%90%88-%e7%ac%ac%e5%9b%9b%e9%83%a8%e5%88%86%ef%bc%9a%e4%b8%8d%e5%af%b9%e7%a7%b0%e7%9a%84%e9%85%b0%e8%83%ba%e5%92%8c","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/recentpaper\/2018\/07\/%e5%8f%af%e4%bb%a5%e6%97%a0%e9%99%90%e7%8e%a9%e8%8a%b1%e7%9a%84aldol%e7%bc%a9%e5%90%88-%e7%ac%ac%e5%9b%9b%e9%83%a8%e5%88%86%ef%bc%9a%e4%b8%8d%e5%af%b9%e7%a7%b0%e7%9a%84%e9%85%b0%e8%83%ba%e5%92%8c.html","title":{"rendered":"\u53ef\u4ee5\u65e0\u9650\u73a9\u82b1\u7684Aldol\u7f29\u5408 \u7b2c\u56db\u90e8\u5206\uff1a\u4e0d\u5bf9\u79f0\u7684\u9170\u80fa\u548c\u916f\u7684\u53cd\u5e94\uff082\uff09\u548cLewis\u78b1\u50ac\u5316\u7684\u53cd\u5e94"},"content":{"rendered":"

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  1. Kiyooka-Corey\u7684\u6076\u5511\u787c\u70f7\u50ac\u5316\u5242<\/li>\n<\/ol>\n

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    1. Evans\u5f00\u53d1\u7684\u624b\u6027BOX\u548cpyBOX\u50ac\u5316\u5242<\/li>\n<\/ol>\n

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      \u57282000\u5e74\uff0cEvans\u8bfe\u9898\u7ec4\u5b8c\u6210\u4e86\u5bf9phorboxazole B\u768427\u6b65\u5168\u5408\u6210\uff0c\u5408\u6210\u7684\u8fc7\u7a0b\u4e2d\u591a\u6b21\u5229\u7528\u4e86\u4e0d\u5bf9\u79f0\u7684aldol\u7f29\u5408\u6765\u6784\u7b51C-C\u78b1\uff0c\u5e76\u4e14\u53cd\u5e94\u7684\u7acb\u4f53\u9009\u62e9\u6027\u90fd\u975e\u5e38\u597d\uff1aref 7<\/p>\n

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      Danmark\u5f00\u53d1\u4e86\u4e00\u79cd\u5229\u7528Lewis\u78b1\u50ac\u5316\u7684\u7845\u70ef\u9187\u919a\u53c2\u4e0e\u7684aldol\u53cd\u5e94\uff0c\u5e76\u4e14\u53cd\u5e94\u4e0d\u9700\u8981\u91d1\u5c5e\u7684\u53c2\u4e0e\uff0c\u53cd\u5e94\u7814\u7a76\u53d1\u73b0\u4f7f\u7528\u6781\u6027\u6eb6\u5242\u53ef\u4ee5\u52a0\u901f\u53cd\u5e94\u7684\u901f\u7387\uff0c\u63d0\u9ad8\u53cd\u5e94\u7684\u6548\u7387\u3002\u4f8b\u5982\uff1a<\/p>\n

      1).ref 8<\/p>\n

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      2).ref 9<\/p>\n

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      \u53ef\u7528\u7684Lewis\u78b1\uff1aref 10<\/p>\n

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      \u53cd\u5e94\u53ef\u80fd\u7684\u8fc7\u6e21\u6001\uff1aref 11<\/p>\n

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      \u5176\u4ed6\u7684\u4e00\u4e9b\u5b9e\u4f8b\uff1a<\/p>\n

      1).ref 12<\/p>\n

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      2). ref 13<\/p>\n

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      3). ref 14<\/p>\n

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      4). ref 15<\/p>\n

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      5). ref 5<\/p>\n

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      6). ref 6<\/p>\n

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      \u53c2\u8003\u6587\u732e<\/strong><\/h4>\n
        \n
      1. J. Org. Chem.<\/em>,\u00a01991<\/strong>,\u00a056<\/em>(7), pp 2276\u20132278, DOI:\u00a0<\/strong>10.1021\/jo00007a003<\/li>\n
      2. Tetrahedron Lett.,<\/em><\/a> 1992 6907<\/em>, DOI: <\/strong>1016\/S0040-4039(00)60892-4<\/a><\/li>\n
      3. Org. Lett.<\/em>,\u00a02010<\/strong>,\u00a012<\/em>(22), pp 5088\u20135091, DOI:\u00a0<\/strong>10.1021\/ol102234k<\/li>\n
      4. J. Am. Chem. Soc.<\/em>,\u00a01997<\/strong>,\u00a0119<\/em>(44), pp 10859\u201310860, DOI:\u00a0<\/strong>10.1021\/ja972547s<\/li>\n
      5. J. Am. Chem. Soc.<\/em>,\u00a02000<\/strong>,\u00a0122<\/em>(16), pp 3811\u20133820, DOI:\u00a0<\/strong>10.1021\/ja9939439<\/li>\n
      6. J. Org. Chem.<\/em>,\u00a01998<\/strong>,\u00a063<\/em>(26), pp 9739\u20139745, DOI:\u00a0<\/strong>10.1021\/jo981218v<\/li>\n
      7. J. Am. Chem. Soc.<\/em>,\u00a02000<\/strong>,\u00a0122<\/em>(41), pp 10033\u201310046, DOI:\u00a0<\/strong>10.1021\/ja002356g<\/li>\n
      8. J. Am. Chem. Soc.<\/em>,\u00a01999<\/strong>,\u00a0121<\/em>(21), pp 4982\u20134991, DOI:\u00a0<\/strong>10.1021\/ja984123j<\/li>\n
      9. J. Am. Chem. Soc.<\/em>,\u00a02000<\/strong>,\u00a0122<\/em>(37), pp 8837\u20138847, DOI:\u00a0<\/strong>10.1021\/ja001023g<\/li>\n
      10. J. Am. Chem. Soc.<\/em>,\u00a01999<\/strong>,\u00a0121<\/em>(21), pp 4982\u20134991, DOI:\u00a0<\/strong>10.1021\/ja984123j<\/li>\n
      11. J. Am. Chem. Soc.<\/em>,\u00a01999<\/strong>,\u00a0121<\/em>(21), pp 4982\u20134991, DOI:\u00a0<\/strong>10.1021\/ja984123j<\/li>\n
      12. J. Org. Chem.<\/em>,\u00a01998<\/strong>,\u00a063<\/em>(25), pp 9524\u20139527, DOI:\u00a0<\/strong>10.1021\/jo981739i<\/li>\n
      13. Org. Lett.<\/em>,\u00a02002<\/strong>,\u00a04<\/em>(20), pp 3473\u20133476, DOI:\u00a0<\/strong>10.1021\/ol026593v<\/li>\n
      14. Angew. Chem. Int. Ed.<\/em>, 2001, 4759, DOI<\/strong>: 10.1002\/1521-3773(20011217)40:24<4759::AID-ANIE4759>3.0.CO;2-G<\/a><\/li>\n
      15. J. Am. Chem. Soc.<\/em>,\u00a01988<\/strong>,\u00a0110<\/em>(2), pp 649\u2013651, DOI:\u00a0<\/strong>10.1021\/ja00210a083<\/li>\n<\/ol>\n

        \u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c<\/strong>\u00a0\u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"\u672c\u6587\u4f5c\u8005 \u5b59\u82cf\u8d5f \u672c\u5e16\u63a5\u4e0a\u7bc7 \u4e00\u3001\u4e0d\u5bf9\u79f0\u7684\u9170\u80fa\u548c\u916f\u7684\u53cd\u5e94 Kiyooka-Corey\u7684\u6076\u5511\u787c\u70f7\u50ac\u5316\u5242 1). ref 1 2). ref 2 3).ref 3 Evans\u5f00\u53d1\u7684\u624b\u6027BOX\u548cpyBOX\u50ac\u5316\u5242 1).ref 4 2). 3). \u8fd9\u7c7b\u53cd\u5e94\u53ef\u80fd\u7684\u5faa\u73af\u50ac\u5316\u7684\u673a\u7406\uff1a \u53cd\u5e94\u4ea7\u7269\u7684\u7acb\u4f53\u5316\u5b66\u53ef\u4ee5\u7528\u4ee5\u4e0b\u6a21\u578b\u6765\u89e3\u91ca\uff1a \u57282000\u5e74\uff0cEvans\u8bfe\u9898\u7ec4\u5b8c\u6210\u4e86\u5bf9phorboxazole B\u768427\u6b65\u5168\u5408\u6210\uff0c\u5408\u6210\u7684\u8fc7\u7a0b\u4e2d\u591a\u6b21\u5229\u7528\u4e86\u4e0d\u5bf9\u79f0\u7684aldol\u7f29\u5408\u6765\u6784\u7b51C-C\u78b1\uff0c\u5e76\u4e14\u53cd\u5e94\u7684\u7acb\u4f53\u9009\u62e9\u6027\u90fd\u975e\u5e38\u597d\uff1aref 7 \u4e8c\u3001Lewis\u78b1\u50ac\u5316\u7684\u4e09\u6c2f\u7845\u70ef\u9187\u7684\u53cd\u5e94 Danmark\u5f00\u53d1\u4e86\u4e00\u79cd\u5229\u7528Lewis\u78b1\u50ac\u5316\u7684\u7845\u70ef\u9187\u919a\u53c2\u4e0e\u7684aldol\u53cd\u5e94\uff0c\u5e76\u4e14\u53cd\u5e94\u4e0d\u9700\u8981\u91d1\u5c5e\u7684\u53c2\u4e0e\uff0c\u53cd\u5e94\u7814\u7a76\u53d1\u73b0\u4f7f\u7528\u6781\u6027\u6eb6\u5242\u53ef\u4ee5\u52a0\u901f\u53cd\u5e94\u7684\u901f\u7387\uff0c\u63d0\u9ad8\u53cd\u5e94\u7684\u6548\u7387\u3002\u4f8b\u5982\uff1a 1).ref 8 2).ref 9 \u53ef\u7528\u7684Lewis\u78b1\uff1aref 10 \u53cd\u5e94\u53ef\u80fd\u7684\u8fc7\u6e21\u6001\uff1aref 11 \u5176\u4ed6\u7684\u4e00\u4e9b\u5b9e\u4f8b\uff1a 1).ref 12 2). ref 13 3). ref 14 4). ref 15 5). ref 5 6). ref 6 \u53c2\u8003\u6587\u732e J. Org. Chem.,\u00a01991,\u00a056(7), pp 2276\u20132278, DOI:\u00a010.1021\/jo00007a003 Tetrahedron Lett., 1992 6907, DOI: 1016\/S0040-4039(00)60892-4 Org. Lett.,\u00a02010,\u00a012(22), pp 5088\u20135091, DOI:\u00a010.1021\/ol102234k J. Am. Chem. Soc.,\u00a01997,\u00a0119(44), pp 10859\u201310860, DOI:\u00a010.1021\/ja972547s J. Am. Chem. Soc.,\u00a02000,\u00a0122(16), pp 3811\u20133820, DOI:\u00a010.1021\/ja9939439 J. Org. Chem.,\u00a01998,\u00a063(26), pp 9739\u20139745, DOI:\u00a010.1021\/jo981218v J. Am. Chem. Soc.,\u00a02000,\u00a0122(41), pp 10033\u201310046, DOI:\u00a010.1021\/ja002356g J. Am. Chem. Soc.,\u00a01999,\u00a0121(21), pp 4982\u20134991, DOI:\u00a010.1021\/ja984123j J. Am. Chem. Soc.,\u00a02000,\u00a0122(37), pp 8837\u20138847, DOI:\u00a010.1021\/ja001023g […]","protected":false},"author":8,"featured_media":19148,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1271],"tags":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/05\/0cover.gif","jetpack_shortlink":"https:\/\/wp.me\/p96op1-4ZB","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/19195"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=19195"}],"version-history":[{"count":9,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/19195\/revisions"}],"predecessor-version":[{"id":27083,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/19195\/revisions\/27083"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/19148"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=19195"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=19195"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=19195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}