{"id":19733,"date":"2018-08-21T05:57:33","date_gmt":"2018-08-20T21:57:33","guid":{"rendered":"\/\/www.gsbet888.com\/?p=19733"},"modified":"2019-08-02T18:51:24","modified_gmt":"2019-08-02T10:51:24","slug":"%e4%b8%89%e9%94%ae%e7%9a%84%e5%bd%a2%e6%88%90%e5%92%8c%e4%b8%89%e9%94%ae%e5%88%b0%e5%8f%8c%e9%94%ae%e7%9a%84%e8%bd%ac%e5%8c%96-%e7%ac%ac%e4%b8%80%e9%83%a8%e5%88%86%ef%bc%9acorey-fuchs%e5%8f%8d","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/2018\/08\/%e4%b8%89%e9%94%ae%e7%9a%84%e5%bd%a2%e6%88%90%e5%92%8c%e4%b8%89%e9%94%ae%e5%88%b0%e5%8f%8c%e9%94%ae%e7%9a%84%e8%bd%ac%e5%8c%96-%e7%ac%ac%e4%b8%80%e9%83%a8%e5%88%86%ef%bc%9acorey-fuchs%e5%8f%8d.html","title":{"rendered":"\u4e09\u952e\u7684\u5f62\u6210\u548c\u4e09\u952e\u5230\u53cc\u952e\u7684\u8f6c\u5316 \u7b2c\u4e00\u90e8\u5206\uff1aCorey-Fuchs\u53cd\u5e94\uff0cSeyferth-Gilbert\u53cd\u5e94\u548c\u7094\u70c3\u590d\u5206\u89e3"},"content":{"rendered":"
\u4f5c\u8005 \u5b59\u82cf\u8d5f<\/p>\n
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\u6362\u53e5\u8bdd\u8bf4\uff0c\u70ef\u548c\u7094\u53ef\u4ee5\u76f8\u4e92\u8f6c\u5316\uff0c\u5728\u4e00\u5b9a\u6761\u4ef6\u4e0b\u7094\u53ef\u4ee5\u88ab\u8fd8\u539f\u6210\u70ef\uff0c\u800c\u70ef\u5728\u4e00\u5b9a\u6761\u4ef6\u4e0b\u70ef\u4e5f\u53ef\u4ee5\u8131\u6c22\u6c27\u5316\u6210\u7094\u3002<\/p>\n \u4e00\u3001\u76f4\u63a5\u6cd5\u751f\u6210\u7094\u70c3<\/p>\n (i) Corey-Fuchs\u53cd\u5e94 ref. 1<\/p>\n \u8fd9\u662f\u4e00\u4e2a\u975e\u5e38\u6709\u7528\u7684\u7528\u4e8e\u751f\u6210\u7094\u70c3\u7684\u4e24\u90e8\u53cd\u5e94\uff0c\u8fd9\u4e2a\u53cd\u5e94\u53ef\u7528\u4e8e\u4ece\u919b\u4e3a\u53cd\u5e94\u5e95\u7269\u5408\u6210\u7aef\u4f4d\u7094\u70c3\u548c\u4e09\u53d6\u4ee3\u7684\u7094\uff1b\u53cd\u5e94\u7684\u7b2c\u4e00\u90e8\u5176\u5b9e\u548cWittig\u53cd\u5e94\u975e\u5e38\u7c7b\u4f3c\u3002<\/p>\n \u53cd\u5e94\u673a\u7406\uff1a<\/p>\n \u4e00\u4e2a\u5b9e\u4f8b\uff1aref. 2<\/p>\n (ii) Seyferth-Gilbert\u53cd\u5e94 ref. 3<\/p>\n Seyferth-Gilbert\u53cd\u5e94\u53ef\u4ee5\u5f53\u4f5cSeyferth-Gilbert\u53cd\u5e94\u7528\u4e8e\u5408\u6210\u7aef\u4f4d\u7094\u70c3\u7684\u4e00\u4e2a\u66ff\u4ee3\u53cd\u5e94\u3002\u4ece\u673a\u7406\u4e0a\u6765\u770b\uff0cSeyferth-Gilbert\u53cd\u5e94\u548cHEW\u53cd\u5e94\u7684\u673a\u7406\u975e\u5e38\u76f8\u4f3c\uff0c\u90fd\u751f\u6210\u4e86\u6709\u6742\u539f\u5b50\u7684\u56db\u5143\u73af\u4e2d\u95f4\u4f53\uff1a<\/p>\n \u4e00\u4e2a\u5b9e\u4f8b\uff1aref. 4<\/p>\n (iii) Seyferth-Gilbert\u53cd\u5e94Ohira-Bestmann\u7684\u6539\u8fdb\uff1a<\/p>\n (1) \u53cd\u5e94\u4e2d\u4f7f\u7528\u7684\u662fOhira-Bestmann\u8bd5\u5242 (ref. 5):<\/p>\n (2) ref. 6<\/p>\n \u53cd\u5e94\u673a\u7406\uff1a<\/p>\n \u5728Ohira-Bestmann\u7684\u6539\u8fdb\u4e2d\uff0c\u91cd\u6c2e\u78f7\u8bd5\u5242\u662f\u7531\u53cd\u5e94\u4e2d\u7684\u4e59\u9170\u5316\u5408\u7269\u76f4\u63a5\u751f\u6210\u7684\uff0c\u56e0\u6b64\u53cd\u5e94\u4e2d\u7684\u78b1\u53ef\u4ee5\u4f7f\u7528\u78b1\u6027\u8f83\u5f31\u7684\u78b1\u3002<\/p>\n (i) \u7094\u70c3\u590d\u5206\u89e3\u53cd\u5e94<\/p>\n \u56e0\u4e3a\u4ea4\u53c9\u590d\u5206\u89e3\u53cd\u5e94\u7684\u6027\u8d28\u6240\u51b3\u5b9a\uff0c\u7094\u70c3\u590d\u5206\u89e3\u53cd\u5e94\u901a\u5e38\u662f\u53d1\u751f\u5728\u5206\u5b50\u5185\u7684\u53cd\u5e94\u6216\u8005\u662f\u540c\u79cd\u5206\u5b50\u4e4b\u95f4\u7684\u590d\u5206\u89e3\u53cd\u5e94\u3002\u53e6\u4e00\u4e2a\u53ef\u4ee5\u89e3\u51b3\u7684\u95ee\u9898\u662f\uff0c\u5bf9\u4e8e\u5927\u73af\u5316\u5408\u7269\u4e2d\u53cc\u952e\u7684\u5408\u6210\uff0c\u70ef\u70c3\u590d\u5206\u89e3\u53cd\u5e94\u5e38\u662f\u4e00\u4e2a\u6709\u7528\u7684\u7b56\u7565\uff0c\u4f46\u662f\u9009\u62e9\u6027\u5f80\u5f80\u4e0d\u597d\uff0c\u800c\u901a\u8fc7\u7094\u70c3\u590d\u5206\u89e3\u53cd\u5e94\u53ef\u4ee5\u5f97\u5230\u4e09\u952e\uff0c\u518d\u901a\u8fc7\u4f7f\u7528\u9009\u62e9\u6027\u7684\u8fd8\u539f\u8bd5\u5242\uff0c\u5c31\u53ef\u4ee5\u751f\u6210\u7acb\u4f53\u8f6c\u79fb\u7684Z<\/em>\u6216\u662fE<\/em>\u6784\u5f62\u7684\u53cc\u952e\u4e86\u3002<\/p>\n \u53cd\u5e94\u50ac\u5316\u5242\uff1aref. 7, 8<\/p>\n \u6b64\u5916\u8fd8\u6709\u4e00\u79cd\u66f4\u52a0\u7a33\u5b9a\u4e14\u6613\u64cd\u4f5c\u7684\u50ac\u5316\u5242\uff1aref. 9, 10<\/p>\n \u53cd\u5e94\u673a\u7406\u548c\u70ef\u70c3\u590d\u5206\u89e3\u5341\u5206\u7c7b\u4f3c\uff1a<\/p>\n \u5173\u73af\u7094\u70c3\u590d\u5206\u89e3\u53cd\u5e94\uff1aref. 11, 12<\/p>\n \u5728\u590d\u5206\u89e3\u53cd\u5e94\u4e4b\u540e\u52a0\u5165\u8fd8\u539f\u5242\uff0c\u901a\u8fc7\u63a7\u5236\u8fd8\u539f\u8fc7\u7a0b\u7684\u9009\u62e9\u6027\u53ef\u4ee5\u5f97\u5230\u4e24\u79cd\u4e0d\u540c\u6784\u5f62\u7684\u5927\u73af\u53cc\u952e\u5316\u5408\u7269\u3002\u4f8b\u5982\uff1aref. 13<\/p>\n \u8fd9\u4e2a\u6b65\u9aa4\u662f\u5408\u6210epothilone C\u4e2d\u7684\u5173\u952e\u6b65\u9aa4\uff0c\u867d\u7136\u53cd\u5e94\u4ea7\u7269\u4e2d\u7684\u53cc\u952e\u53ef\u4ee5\u901a\u8fc7\u70ef\u70c3\u590d\u5206\u89e3\u5f97\u5230\uff0c\u4f46\u662f\u70ef\u70c3\u590d\u5206\u89e3\u53ea\u80fd\u5f97\u5230\u4e24\u79cd\u53cc\u952e\u5f02\u6784\u4f53\u7684\u6df7\u5408\u7269\uff0c\u9009\u62e9\u6027\u4e0d\u597d\u3002<\/p>\n <\/p>\n<\/a><\/p>\n
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REFERENCES<\/strong><\/h4>\n
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