{"id":20467,"date":"2018-09-17T18:53:44","date_gmt":"2018-09-17T10:53:44","guid":{"rendered":"\/\/www.gsbet888.com\/?p=20467"},"modified":"2019-08-02T18:51:15","modified_gmt":"2019-08-02T10:51:15","slug":"a%e5%80%bc%ef%bc%88a-value%ef%bc%89","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/reactions\/2018\/09\/a%e5%80%bc%ef%bc%88a-value%ef%bc%89.html","title":{"rendered":"A\u503c\uff08A value\uff09"},"content":{"rendered":"<p><strong>A\u503c\uff08A value\uff09<\/strong>\u6307\u7684\u662f1955\u5e74Winstein\u548cHolness\u62a5\u9053\u7684\u5355\u53d6\u4ee3\u73af\u5df1\u70f7\u4e2deq-\u53d6\u4ee3\u548cax-\u53d6\u4ee3\u4e4b\u95f4\u5e73\u8861\u5409\u5e03\u65af\u81ea\u7531\u80fd\uff08\u5dee\u5f02\uff09\u7684\u53d8\u5316\u503c\u3002<\/p>\n<p>\u8be5\u503c\u662f\u53cd\u5e94\u73af\u5df1\u70f7\u6784\u8c61\u5f02\u6784\u4f53\u7684\u5b58\u5728\u6bd4\u4f8b\u548c\u53d6\u4ee3\u57fa\u7684\u7a7a\u95f4\u5f71\u54cd\u7684\u4e00\u4e2a\u6307\u6807\u3002\u6211\u4eec\u8fd8\u53ef\u4ee5\u901a\u8fc7\u4ece\u5355\u4e00\u53d6\u4ee3\u5ef6\u4f38\u6765\u8003\u8651\u591a\u53d6\u4ee3\u73af\u5df1\u70f7\u7684\u53d6\u4ee3\u57fa\u7684\u5f71\u54cd\u3002\u540c\u65f6\uff0c\u5b83\u8fd8\u53ef\u4f5c\u4e3a\u8003\u8651\u53cd\u5e94\u9009\u62e9\u6027\u5f71\u54cd\u7684\u6307\u6807\u3002<\/p>\n<p>\u522b\u540d\u4e3a<strong>Winstein\u2013Holness A value<\/strong>\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20468 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/A-value-e1484311420444.jpg\" alt=\"\" width=\"500\" height=\"148\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/A-value-e1484311420444.jpg 500w, https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/A-value-e1484311420444-300x89.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20472 size-large\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/7dd4c3f74f006b34bb1d70d7adebd54e-3-680x690.png\" alt=\"\" width=\"680\" height=\"690\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/7dd4c3f74f006b34bb1d70d7adebd54e-3-680x690.png 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/7dd4c3f74f006b34bb1d70d7adebd54e-3-296x300.png 296w, https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/7dd4c3f74f006b34bb1d70d7adebd54e-3-768x779.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/7dd4c3f74f006b34bb1d70d7adebd54e-3.png 1109w\" sizes=\"(max-width: 680px) 100vw, 680px\" \/><\/p>\n<p>\u7531\u4e8e\u8be5\u503c\u53ea\u662f\u4ee3\u8868\u4e86\u5e73\u8861\u7684\u5409\u5e03\u65af\u81ea\u7531\u80fd\uff0c\u56e0\u6b64\u7acb\u4f53\u4f4d\u963b\u867d\u7136\u662f\u4e00\u4e2a\u9700\u8981\u8003\u8651\u7684\u56e0\u7d20\uff0c\u4f46\u662f\u4e25\u5bc6\u7684\u6765\u8bf4\u8fd9\u662f\u4ee3\u8868\u4e86\u73af\u5df1\u70f7\u81ea\u8eab\u5468\u8fb9\u7684\u4f4d\u963b\u5927\u5c0f\uff0c\u5e76\u975e\u5355\u5355\u662f\u53d6\u4ee3\u57fa\u7684\u4f4d\u963b\u5927\u5c0f\u51b3\u5b9a\u7684\u3002<br \/>\n\u4f8b\u5982\u53d6\u4ee3\u57fa\u4e3aC(CH<sub>3<\/sub>)<sub>3<\/sub>\u7684\u65f6\u5019\uff0cA\u503c\u8d85\u8fc7\u4e864\uff0c\u800c\u4e0a\u56fe\u6240\u793a\u7684TMS\u53d6\u4ee3\u7684\u65f6\u5019A\u503c\u53ea\u67092.5\u3002\u56e0\u6b64\u53d6\u4ee3\u57fa\u7684\u7acb\u4f53\u4f4d\u963b\u5927\u5c0f\u4e0eA\u503c\u5e76\u4e0d\u662f\u6210\u6b63\u76f8\u5173\u7684\u3002\u8fd9\u91cc\u5176\u5b9e\u662f\u7531\u4e8eC-Si\u7684\u952e\u6bd4C-C\u957f\uff0c\u6700\u7ec8A\u503c\u5c31\u5c0f\u7684\u7f18\u6545\u3002<\/p>\n<h4>\u53c2\u8003\u6587\u732e<\/h4>\n<ol>\n<li>B. S. Winsten, N. J. Holness,\u00a0<em>J. Am. Chem. Soc.<\/em>,\u00a0<strong>1955<\/strong>,\u00a0<em>77<\/em>, 5562. DOI:\u00a0<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja01626a037?journalCode=jacsat&amp;quickLinkVolume=77&amp;quickLinkPage=5562&amp;selectedTab=citation&amp;volume=77\">10.1021\/ja01626a037<\/a><\/li>\n<li>F. R. Jensen, C. H. BushWeller, B. H. Beck,\u00a0<em>J. Am. Chem. Soc.<\/em>,\u00a0<strong>1968<\/strong>,\u00a0<em>91<\/em>, 344. DOI:\u00a0<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja01030a023?journalCode=jacsat&amp;quickLinkVolume=91&amp;quickLinkPage=344&amp;selectedTab=citation&amp;volume=91\">10.1021\/ja01030a023<\/a><\/li>\n<li>E. L. Eliel, H. Satici,\u00a0<em>J. Org. Chem.<\/em>,\u00a0<strong>1994<\/strong>,\u00a0<em>59<\/em>, 688. DOI:<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jo00082a036?journalCode=joceah&amp;quickLinkVolume=59&amp;quickLinkPage=688&amp;selectedTab=citation&amp;volume=59\">\u00a010.1021\/jo00082a036<\/a><\/li>\n<li>C. H. Marzabadi, J. E. Anderson, J. Gonzalez-Outeirino, P. R. J. Gaffney, C. G. H. White, D. A. Tocher, L. J. Todaro,\u00a0<em>J. Am. Chem. Soc.<\/em>,\u00a0<strong>2003<\/strong>,\u00a0<em>123<\/em>, 15163. DOI:\u00a0<a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja035936x?journalCode=jacsat&amp;quickLinkVolume=125&amp;quickLinkPage=15163&amp;selectedTab=citation&amp;volume=125\">10.1021\/ja035936x<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/A_value\">https:\/\/en.wikipedia.org\/wiki\/A_value<\/a><\/li>\n<\/ol>\n<p><strong>\u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/strong> <\/p>\n","protected":false},"excerpt":{"rendered":"A\u503c\uff08A value\uff09\u6307\u7684\u662f1955\u5e74Winstein\u548cHolness\u62a5\u9053\u7684\u5355\u53d6\u4ee3\u73af\u5df1\u70f7\u4e2deq-\u53d6\u4ee3\u548cax-\u53d6\u4ee3\u4e4b\u95f4\u5e73\u8861\u5409\u5e03\u65af\u81ea\u7531\u80fd\uff08\u5dee\u5f02\uff09\u7684\u53d8\u5316\u503c\u3002 \u8be5\u503c\u662f\u53cd\u5e94\u73af\u5df1\u70f7\u6784\u8c61\u5f02\u6784\u4f53\u7684\u5b58\u5728\u6bd4\u4f8b\u548c\u53d6\u4ee3\u57fa\u7684\u7a7a\u95f4\u5f71\u54cd\u7684\u4e00\u4e2a\u6307\u6807\u3002\u6211\u4eec\u8fd8\u53ef\u4ee5\u901a\u8fc7\u4ece\u5355\u4e00\u53d6\u4ee3\u5ef6\u4f38\u6765\u8003\u8651\u591a\u53d6\u4ee3\u73af\u5df1\u70f7\u7684\u53d6\u4ee3\u57fa\u7684\u5f71\u54cd\u3002\u540c\u65f6\uff0c\u5b83\u8fd8\u53ef\u4f5c\u4e3a\u8003\u8651\u53cd\u5e94\u9009\u62e9\u6027\u5f71\u54cd\u7684\u6307\u6807\u3002 \u522b\u540d\u4e3aWinstein\u2013Holness A value\u3002 \u7531\u4e8e\u8be5\u503c\u53ea\u662f\u4ee3\u8868\u4e86\u5e73\u8861\u7684\u5409\u5e03\u65af\u81ea\u7531\u80fd\uff0c\u56e0\u6b64\u7acb\u4f53\u4f4d\u963b\u867d\u7136\u662f\u4e00\u4e2a\u9700\u8981\u8003\u8651\u7684\u56e0\u7d20\uff0c\u4f46\u662f\u4e25\u5bc6\u7684\u6765\u8bf4\u8fd9\u662f\u4ee3\u8868\u4e86\u73af\u5df1\u70f7\u81ea\u8eab\u5468\u8fb9\u7684\u4f4d\u963b\u5927\u5c0f\uff0c\u5e76\u975e\u5355\u5355\u662f\u53d6\u4ee3\u57fa\u7684\u4f4d\u963b\u5927\u5c0f\u51b3\u5b9a\u7684\u3002 \u4f8b\u5982\u53d6\u4ee3\u57fa\u4e3aC(CH3)3\u7684\u65f6\u5019\uff0cA\u503c\u8d85\u8fc7\u4e864\uff0c\u800c\u4e0a\u56fe\u6240\u793a\u7684TMS\u53d6\u4ee3\u7684\u65f6\u5019A\u503c\u53ea\u67092.5\u3002\u56e0\u6b64\u53d6\u4ee3\u57fa\u7684\u7acb\u4f53\u4f4d\u963b\u5927\u5c0f\u4e0eA\u503c\u5e76\u4e0d\u662f\u6210\u6b63\u76f8\u5173\u7684\u3002\u8fd9\u91cc\u5176\u5b9e\u662f\u7531\u4e8eC-Si\u7684\u952e\u6bd4C-C\u957f\uff0c\u6700\u7ec8A\u503c\u5c31\u5c0f\u7684\u7f18\u6545\u3002 \u53c2\u8003\u6587\u732e B. S. Winsten, N. J. Holness,\u00a0J. Am. Chem. Soc.,\u00a01955,\u00a077, 5562. DOI:\u00a010.1021\/ja01626a037 F. R. Jensen, C. H. BushWeller, B. H. Beck,\u00a0J. Am. Chem. Soc.,\u00a01968,\u00a091, 344. DOI:\u00a010.1021\/ja01030a023 E. L. Eliel, H. Satici,\u00a0J. Org. Chem.,\u00a01994,\u00a059, 688. DOI:\u00a010.1021\/jo00082a036 C. H. Marzabadi, J. E. Anderson, J. Gonzalez-Outeirino, P. R. J. Gaffney, C. G. H. White, D. A. Tocher, L. J. Todaro,\u00a0J. Am. Chem. Soc.,\u00a02003,\u00a0123, 15163. DOI:\u00a010.1021\/ja035936x https:\/\/en.wikipedia.org\/wiki\/A_value \u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0Chem-Station\u5316\u5b66\u7a7a\u95f4\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01","protected":false},"author":5,"featured_media":20473,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2],"tags":[2334,2333],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2018\/09\/2017-01-18_03-14-02.png","jetpack_shortlink":"https:\/\/wp.me\/p96op1-5k7","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/20467"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=20467"}],"version-history":[{"count":5,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/20467\/revisions"}],"predecessor-version":[{"id":27015,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/20467\/revisions\/27015"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/20473"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=20467"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=20467"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=20467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}