{"id":26202,"date":"2019-07-18T08:00:45","date_gmt":"2019-07-18T00:00:45","guid":{"rendered":"\/\/www.gsbet888.com\/?p=26202"},"modified":"2019-07-17T22:15:42","modified_gmt":"2019-07-17T14:15:42","slug":"%e4%bd%8e%e4%ba%8e1mg%e7%9a%84%e5%9b%ba%e4%bd%93%e8%af%95%e5%89%82%e6%80%8e%e4%b9%88%e5%bf%ab%e9%80%9f%e7%b2%be%e7%a1%ae%e7%a7%b0%e9%87%8f%ef%bc%9f","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/recentpaper\/2019\/07\/%e4%bd%8e%e4%ba%8e1mg%e7%9a%84%e5%9b%ba%e4%bd%93%e8%af%95%e5%89%82%e6%80%8e%e4%b9%88%e5%bf%ab%e9%80%9f%e7%b2%be%e7%a1%ae%e7%a7%b0%e9%87%8f%ef%bc%9f.html","title":{"rendered":"\u4f4e\u4e8e1mg\u7684\u56fa\u4f53\u8bd5\u5242\u600e\u4e48\u5feb\u901f\u7cbe\u786e\u79f0\u91cf\uff1f"},"content":{"rendered":"

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High\u2010Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Bead<\/p>\n

Noah P. Tu, Amanda W. Dombrowski, Gashaw M. Goshu, Anil Vasudevan, Stevan W. Djuric, and Ying Wang<\/p>\n

Angew. Chem. Int. Ed., 2019, 58, 7987-7991. DOI\uff1a10.1002\/anie.201900536.<\/p><\/blockquote>\n

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\u56fe2. \u5316\u5b66\u73bb\u7483\u73e0\u79f0\u91cf\u52fa. \u56fe\u7247\u6765\u6e90\uff1aAngew. Chem. Int. Ed.<\/em><\/p>\n

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\u4f5c\u8005\u9009\u7528\u7684Suzuki-Miyaura\u53cd\u5e94\u6761\u4ef6\u670955\u4e2a\uff0c\u7528Chemspeed\u8bbe\u7f6e\u5b8c\u6bd5\u3002\u6761\u4ef6\u7b5b\u9009\u53ea\u8003\u8651\u6536\u7387\uff0c\u5176\u4ed6\u5982\u53cd\u5e94\u6eb6\u5242\u3001\u8bd5\u5242\u7684\u7269\u7406\u6027\u8d28\u5982\u6eb6\u89e3\u5ea6\u7b49\u7edf\u7edf\u4e0d\u8003\u8651\u3002\u4ee5\u5316\u5408\u72695-\u6eb4-\u5432\u54da-2-\u916e\uff08\u5316\u5408\u72691<\/strong>\uff09\u4e3a\u4f8b\uff0c\u8fd9\u5728\u8bb8\u591aSuzuki-Miyaura\u53cd\u5e94\u6761\u4ef6\u4e2d\u66fe\u96be\u4ee5\u9a6f\u670d\uff0c\u5982\u56fe3\u6240\u793a\u3002\u8f89\u745e\u7684\u5316\u5b66\u5bb6\u5728\u57fa\u4e8e\u6d41\u52a8\u5316\u5b66\u7b5b\u9009\u5e73\u53f0\u9009\u51fa\u4e86\u6700\u4f18\u7684\u6761\u4ef6\uff0c\u5206\u79bb\u6536\u738781%\uff0c\u800c\u901a\u8fc7\u4f5c\u8005\u7684\u7b5b\u9009\u4f53\u7cfb\uff0c\u6700\u597d\u7684\u6536\u7387\u8fbe\u523082%\u548c89%\u3002\u8fd9\u8bf4\u660e\uff0c\u6709\u6548\u7684\u6761\u4ef6\u7b5b\u9009\u624d\u80fd\u53ef\u80fd\u786e\u5b9a\u6700\u6709\u6548\u7684\u53cd\u5e94\u6761\u4ef6\uff0c\u76f8\u6bd4\u800c\u53ea\u62fc\u6570\u91cf\u5e76\u4e0d\u660e\u667a\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u56fe3. Suzuki-Miyaura\u53cd\u5e94. \u56fe\u7247\u6765\u6e90\uff1aAngew. Chem. Int. Ed.<\/em><\/p>\n

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\"\"<\/a><\/p>\n

\"\"<\/a>\u56fe4. C-N\u5076\u8054\u53cd\u5e94. \u56fe\u7247\u6765\u6e90\uff1aAngew. Chem. Int. Ed.<\/em><\/p>\n

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\"\"<\/a><\/p>\n

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\u00a0\u603b\u7ed3\uff1a<\/strong><\/h4>\n

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 <\/p>\n

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Tu, Amanda W. Dombrowski, Gashaw M. Goshu, Anil Vasudevan, Stevan W. Djuric, and Ying Wang Angew. Chem. Int. Ed., 2019, 58, 7987-7991. DOI\uff1a10.1002\/anie.201900536. \u4f5c\u8005\u7684\u521b\u65b0\u6027\u6765\u6e90\u4e8e\u5236\u836f\u5de5\u4e1a\u4e2d\u7528\u5230\u7684\u5e72\u7c89\u5305\u8863\u6280\u672f\u3002\u5c11\u91cf\u7684\u5ba2\u4f53\u9897\u7c92\u4e0e\u5927\u5f97\u591a\u7684\u4e3b\u4f53\u9897\u7c92\u6df7\u5408\uff0c\u5ba2\u4f53\u901a\u8fc7\u8303\u5fb7\u534e\u529b\u9644\u7740\u5728\u4e3b\u4f53\u9897\u7c92\u8868\u9762\uff0c\u800c\u4e14\u5e72\u7c89\u5305\u8863\u64cd\u4f5c\u4ec5\u9700\u4e00\u6b65\uff0c\u5982\u56fe1a\uff0cb\u6240\u793a\u3002 \u56fe1\uff1aa)\u5e72\u6cd5\u5305\u8863\u8fc7\u7a0b b)\u5404\u79cd\u7c7b\u578b\u7684\u5316\u5b66\u73bb\u7483\u73e0\u3002\u56fe\u7247\u6765\u6e90\uff1aAngew. Chem. Int. Ed. \u5728\u9009\u62e9\u4e3b\u4f53\u6750\u6599\u65f6\uff0c\u4f5c\u8005\u6700\u7ec8\u9009\u62e9\u4e86\u73bb\u7483\u73e0\uff0c\u56e0\u4e3a\u5b83\u5177\u6709\u9ad8\u5ea6\u6d41\u52a8\u6027\u3001\u5316\u5b66\u60f0\u6027\uff0c\u4ee5\u53ca\u5149\u6ed1\u5706\u6574\u7684\u8868\u9762\uff0c\u5e76\u7528Resodyn Acoustic Mixer\uff08RAM\uff09\u5e72\u6cd5\u5305\u8863\u673a\uff0c\u53ef\u4ee5\u6df7\u54081-20%\u8d28\u91cf\u6bd4\u7684\u56fa\u4f53\u8bd5\u5242\u3002\u8d1f\u8f7d\u524d\u540e\u7684\u5316\u5b66\u73bb\u7483\u73e0\u7684\u5916\u8c8c\u56fe\u53ef\u4ee5\u901a\u8fc7\u626b\u63cf\u7535\u5b50\u663e\u5fae\u955c\u89c2\u5bdf\uff0c\u56fe1c\u3002 \u56fe1c)\u5316\u5b66\u73bb\u7483\u73e0\uff08SEM\u56fe\uff0c\u5de6155\u500d\u653e\u5927\uff0c\u4e2d800\u500d\u653e\u5927\uff0c\u53f35%Pd(\uff08dppf\uff09Cl2\uff09\u76841800\u500d\u653e\u5927\u3002\u56fe\u7247\u6765\u6e90\uff1aAngew. Chem. Int. 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