{"id":30157,"date":"2020-03-05T08:00:24","date_gmt":"2020-03-05T00:00:24","guid":{"rendered":"\/\/www.gsbet888.com\/?p=30157"},"modified":"2020-07-19T12:48:49","modified_gmt":"2020-07-19T04:48:49","slug":"murai-chatani-kakiuchi-%e5%8f%8d%e5%ba%94","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/reactions\/2020\/03\/murai-chatani-kakiuchi-%e5%8f%8d%e5%ba%94.html","title":{"rendered":"Murai-Chatani-Kakiuchi \u53cd\u5e94"},"content":{"rendered":"<h4><strong>\u6982\u8981<\/strong><\/h4>\n<p>Murai-Chatani-Kakiuchi\u53cd\u5e94 (Murai-Chatani-Kakiuchi Reaction)\u662f\u948c\u50ac\u5316\u5242 (Ru<sub>3<\/sub>(CO)<sub>12<\/sub>, RuH<sub>2<\/sub>(CO)(PPh<sub>3<\/sub>)<sub>3<\/sub>\u53ca[Ru(p-cymene)Cl<sub>2<\/sub>]<sub> 2<\/sub>\u7b49)\u53c2\u4e0e\u7684\u90bb\u4f4d\u5bfc\u5411C-H\u952e\u6d3b\u5316\/\u5b98\u80fd\u56e2\u5316\u53cd\u5e94 (ortho-directed C-H bond activation\/functionalization reaction) <sup>[1]<\/sup>\u3002\u8be5\u53cd\u5e94\u7531\u65e5\u672c\u5927\u962a\u5927\u5b66 (\u5927\u962a\u5927\u5b66\uff0cOsaka university)\u7684\u6751\u4e95\u771f\u4e8c (\u6751\u4e95 \u771f\u4e8c\uff0cMurai Shinji)\u3001 \u8336\u8c37\u76f4\u4eba (\u8336\u8c37 \u76f4\u4eba\uff0c Chatani Naoto)\u53ca\u57a3\u5185\u53f2\u654f (\u57a3\u5185 \u53f2\u654f\uff0cKakiuchi Fumishito) \u7b49\u57281993\u5e74\u9996\u6b21\u62a5\u9053\uff0cMurai-Chatani-Kakiuchi\u4e3a\u9996\u4f8b\u901a\u8fc7\u87af\u5408\u8f85\u52a9\uff0c\u5373\u901a\u8fc7\u5bfc\u5411\u57fa\u4fc3\u8fdb\u7684\u82b3\u9999\u916e\u53ca\u6742\u82b3\u9999\u916e\u7c7b\u5316\u5408\u7269\u4e0e\u70ef\u70c3\u4e4b\u95f4\u7684\u533a\u57df\u9009\u62e9\u6027\u82b3\u57faC-H\u952e\u5b98\u80fd\u56e2\u5316\u53cd\u5e94<sup>[1]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/03\/e2f457ec632c1f6729839285dcf348ab.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-33953 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/03\/e2f457ec632c1f6729839285dcf348ab.png\" alt=\"\" width=\"866\" height=\"334\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/03\/e2f457ec632c1f6729839285dcf348ab.png 866w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/03\/e2f457ec632c1f6729839285dcf348ab-300x116.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/03\/e2f457ec632c1f6729839285dcf348ab-680x262.png 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/03\/e2f457ec632c1f6729839285dcf348ab-768x296.png 768w\" sizes=\"(max-width: 866px) 100vw, 866px\" \/><\/a>1995\u5e74\uff0cMurai\u7814\u7a76\u7ec4\u5bf9\u82b3\u9999\u916e\u53ca\u70ef\u70c3\u5e95\u7269\u7684\u5e94\u7528\u8303\u56f4\u8fdb\u884c\u4e86\u6df1\u5165\u7814\u7a76<sup>[2]<\/sup>\uff0c\u5e76\u5c06\u5e95\u7269\u8303\u56f4\u6269\u5c55\u81f3\u73af\u72b6\u5171\u8f6d\u70ef\u916e<sup>[3]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/2-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30159 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/2-2.png\" alt=\"\" width=\"817\" height=\"124\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/2-2.png 1029w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/2-2-300x45.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/2-2-768x116.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/2-2-680x103.png 680w\" sizes=\"(max-width: 817px) 100vw, 817px\" \/><\/a><\/p>\n<p>1996\u5e74\uff0cMurai\u91c7\u7528Ru<sub>3<\/sub>(CO)<sub>12<\/sub>\u50ac\u5316\u5242\uff0c\u5c06\u5e95\u7269\u6269\u5c55\u81f3\u82b3\u4e9a\u80fa\uff0c\u5e76\u83b7\u5f97\u4f18\u826f\u7684\u4ea7\u7387\u53ca\u533a\u57df\u9009\u62e9\u6027<sup>[4]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/3-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30160 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/3-2.png\" alt=\"\" width=\"589\" height=\"156\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/3-2.png 811w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/3-2-300x80.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/3-2-768x204.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/3-2-680x180.png 680w\" sizes=\"(max-width: 589px) 100vw, 589px\" \/><\/a><\/p>\n<p>1997\u5e74\uff0cMurai\u7ee7\u7eed\u91c7\u7528Ru<sub>3<\/sub>(CO)<sub>12<\/sub>\u50ac\u5316\u5242\uff0c\u6210\u529f\u5b8c\u6210\u4e86\u82ef\u73afC-H\u952e\u7684\u7fb0\u57fa\u5316<sup>[5]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/4-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30161 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/4-2.png\" alt=\"\" width=\"629\" height=\"176\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/4-2.png 981w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/4-2-300x84.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/4-2-768x215.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/4-2-680x190.png 680w\" sizes=\"(max-width: 629px) 100vw, 629px\" \/><\/a><\/p>\n<p>1997\u5e74\uff0cMurai\u91c7\u7528RuH<sub>2<\/sub>(CO)(PPh<sub>3<\/sub>)<sub>3<\/sub>\u50ac\u5316\u5242\uff0c\u6210\u529f\u5b8c\u6210\u975e\u73af\u5171\u8f6d\u70ef\u916e\u70ef\u57faC-H\u952e\u7684\u5b98\u80fd\u56e2\u5316\u53cd\u5e94\uff0c\u540c\u65f6\u5bf9\u53cd\u5e94\u673a\u7406\u8fdb\u884c\u4e86\u7814\u7a76<sup>[6]<\/sup><sub>\u3002<\/sub><\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/5-2.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30162 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/5-2.png\" alt=\"\" width=\"705\" height=\"204\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/5-2.png 1247w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/5-2-300x87.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/5-2-768x222.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/5-2-680x197.png 680w\" sizes=\"(max-width: 705px) 100vw, 705px\" \/><\/a><\/p>\n<p>\u968f\u540e\uff0cMurai\u7814\u7a76\u53d1\u73b0\uff0c\u91c7\u7528\u4e0d\u540c\u7684\u948c\u50ac\u5316\u5242\uff0c\u53ef\u4ee5\u6709\u6548\u5730\u8c03\u63a7\u82b3\u57fa\u5e95\u7269C-H\u952e\u70f7\u57fa\u5316\u8fc7\u7a0b\u7684\u533a\u57df\u9009\u62e9\u6027\uff0c\u540c\u65f6\u8fd8\u53ef\u83b7\u5f97\u6781\u4f73\u7684\u50ac\u5316\u5242\u4e13\u4e00\u6027<sup>[7]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/6-1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30163 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/6-1.png\" alt=\"\" width=\"653\" height=\"210\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/6-1.png 1458w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/6-1-300x97.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/6-1-768x247.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/6-1-680x219.png 680w\" sizes=\"(max-width: 653px) 100vw, 653px\" \/><\/a><\/p>\n<p>1999\u5e74\uff0cMurai\u7b49\u53d1\u73b0\u82b3\u57fa\u8148\u5728RuH<sub>2<\/sub>(CO)(PPh<sub>3<\/sub>)<sub>3<\/sub>\u50ac\u5316\u5242\u5b58\u5728\u7684\u6761\u4ef6\u4e0b\uff0c\u540c\u6837\u53ef\u4ee5\u5b8c\u6210\u4e0e\u70ef\u70c3\u7684\u533a\u57df\u9009\u62e9\u6027\u82b3\u57faC-H\u952e\u70f7\u57fa\u5316\u53cd\u5e94<sup>[8], [12]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/7-1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30164 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/7-1.png\" alt=\"\" width=\"695\" height=\"148\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/7-1.png 1297w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/7-1-300x64.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/7-1-768x164.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/7-1-680x145.png 680w\" sizes=\"(max-width: 695px) 100vw, 695px\" \/><\/a><\/p>\n<p>\u540c\u5e74\uff0cMurai\u7814\u7a76\u7ec4\u8fdb\u4e00\u6b65\u5b8c\u6210\u4e86\u82b3\u57fa\u9170\u4e9a\u80fa\u916f\u7684C-H\u952e\u70ef\u57fa\u5316\u53cd\u5e94<sup>[9], [12]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/8-1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30165 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/8-1.png\" alt=\"\" width=\"689\" height=\"125\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/8-1.png 1306w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/8-1-300x55.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/8-1-768x140.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/8-1-680x124.png 680w\" sizes=\"(max-width: 689px) 100vw, 689px\" \/><\/a><\/p>\n<p>2001\u5e74\uff0cMurai\u7b49\u8fdb\u4e00\u6b65\u5c06\u53cd\u5e94\u5e95\u7269\u6269\u5c55\u81f3\u82b3\u9999\u919b<sup>[10]<\/sup>\u4e0e\u73af\u72b6\u5171\u8f6d\u70ef\u919b<sup>[10]<\/sup>\u53ca\u82b3\u8159<sup>[11], [12]<\/sup>\uff0c\u5e76\u83b7\u5f97\u4f18\u826f\u7684\u4ea7\u7387\u4e0e\u533a\u57df\u9009\u62e9\u6027<sup>[10]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/9-1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30166 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/9-1.png\" alt=\"\" width=\"721\" height=\"239\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/9-1.png 1440w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/9-1-300x99.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/9-1-768x254.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/9-1-680x225.png 680w\" sizes=\"(max-width: 721px) 100vw, 721px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/10.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30167 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/10.png\" alt=\"\" width=\"701\" height=\"226\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/10.png 1317w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/10-300x97.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/10-768x248.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/10-680x219.png 680w\" sizes=\"(max-width: 701px) 100vw, 701px\" \/><\/a><\/p>\n<p>2002\u5e74\uff0cMurai\u5b8c\u6210\u4e86\u948c\u50ac\u5316\u5242\u4fc3\u8fdb\u7684\u7094\u70c3\u5bf9\u5171\u8f6d\u70ef\u916eC-H\u952e\u7684\u5b98\u80fd\u56e2\u5316\u53cd\u5e94\uff0c\u6210\u529f\u83b7\u5f97\u5171\u8f6d\u4e8c\u70ef\u916e\uff0c\u53cd\u5e94\u5177\u6709\u4f18\u826f\u7684\u533a\u57df\u53ca\u7acb\u4f53\u9009\u62e9\u6027<sup>[13]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/11.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30168 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/11.png\" alt=\"\" width=\"723\" height=\"186\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/11.png 1085w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/11-300x77.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/11-768x197.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/11-680x175.png 680w\" sizes=\"(max-width: 723px) 100vw, 723px\" \/><\/a><\/p>\n<p>2003\u5e74\uff0cKakiuchi\u91c7\u7528\u948c\u50ac\u5316\u5242\uff0c\u987a\u5229\u5b9e\u73b0\u4e86\u82b3\u9999\u787c\u9178\u916f\u5bf9\u82b3\u916eC-H\u952e\u7684\u5b98\u80fd\u56e2\u5316\u8fc7\u7a0b\uff0c\u5e76\u53d6\u5f97\u826f\u597d\u7684\u533a\u57df\u9009\u62e9\u6027<sup>[14]<\/sup>\u3002\u4e4b\u540e\uff0cKakiuchi\u5bf9\u5e95\u7269\u8303\u56f4\u53ca\u53cd\u5e94\u673a\u7406\u8fdb\u884c\u4e86\u6df1\u5165\u7814\u7a76<sup>[15]<\/sup>\u30022007\u5e74\uff0cKakiuchi\u53c8\u5c06\u5176\u6269\u5c55\u81f3\u70ef\u57fa\u787c\u9178\u916f<sup>[16]<\/sup>\uff0c\u987a\u5229\u5b8c\u6210\u82b3\u916eC-H\u952e\u7684\u533a\u57df\u9009\u62e9\u6027\u70ef\u57fa\u5316\u30022010\u5e74\uff0cKakiuchi\u901a\u8fc7\u8fdb\u4e00\u6b65\u7814\u7a76\u53d1\u73b0\uff0c\u52a0\u5165\u82ef\u4e59\u70ef\u53ef\u4ee5\u6709\u6548\u5730\u63a7\u5236\u8be5\u53cd\u5e94\u7684\u533a\u57df\u9009\u62e9\u6027<sup>[17]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/12.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30169 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/12.png\" alt=\"\" width=\"753\" height=\"424\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/12.png 1487w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/12-300x169.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/12-768x432.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/12-680x383.png 680w\" sizes=\"(max-width: 753px) 100vw, 753px\" \/><\/a><\/p>\n<p>2006\u5e74\uff0cS. Darses\u4e0eJ. P. Genet\u91c7\u7528\u6d3b\u6027\u66f4\u9ad8\u7684[Ru(p-cymene)Cl<sub>2<\/sub>]<sub> 2<\/sub>\u50ac\u5316\u5242\uff0c\u4f7f\u53cd\u5e94\u4ea7\u7387\u4e0e\u533a\u57df\u9009\u62e9\u6027\u83b7\u5f97\u6781\u5927\u63d0\u5347<sup>[18]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/13.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30170 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/13.png\" alt=\"\" width=\"679\" height=\"204\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/13.png 1457w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/13-300x90.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/13-768x231.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/13-680x204.png 680w\" sizes=\"(max-width: 679px) 100vw, 679px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/14.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30171 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/14.png\" alt=\"\" width=\"684\" height=\"318\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/14.png 1396w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/14-300x139.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/14-768x356.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/14-680x315.png 680w\" sizes=\"(max-width: 684px) 100vw, 684px\" \/><\/a><\/p>\n<p>2008-2009\u5e74\uff0cS. Darses\u4e0eJ. P. Genet\u91c7\u7528\u539f\u4f4d\u751f\u6210\u7684[Ru(p-cymene)Cl<sub>2<\/sub>]<sub> 2<\/sub>\u50ac\u5316\u5242\uff0c\u6210\u529f\u5c06[Ru(p-cymene)Cl<sub>2<\/sub>]<sub>2<\/sub>\u50ac\u5316\u4e0b\u7684\u5e95\u7269\u8303\u56f4\u6269\u5c55\u81f3\u82ef\u4e59\u70ef\uff0c\u540c\u6837\u53ef\u83b7\u5f97\u4f18\u826f\u7684\u533a\u57df\u9009\u62e9\u6027<sup>[19]-[20]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/15.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30172 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/15.png\" alt=\"\" width=\"684\" height=\"290\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/15.png 1439w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/15-300x127.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/15-768x326.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/15-680x289.png 680w\" sizes=\"(max-width: 684px) 100vw, 684px\" \/><\/a><\/p>\n<p>2009\u5e74\uff0cS. Darses\u4e0eJ. P. Genet\u5c06[Ru(p-cymene)Cl<sub>2<\/sub>]<sub> 2<\/sub>\u50ac\u5316\u7684\u53cd\u5e94\u6761\u4ef6\u6210\u529f\u6269\u5c55\u81f3\u5404\u7c7bMichael\u52a0\u6210\u53d7\u4f53\uff0c\u540c\u65f6\u83b7\u5f97\u4f18\u826f\u7684\u4ea7\u7387\u53ca\u4f18\u826f\u7684Michael\u53d7\u4f53\u03b2-\u533a\u57df\u9009\u62e9\u6027<sup>[21]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/16.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30173 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/16.png\" alt=\"\" width=\"702\" height=\"175\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/16.png 1518w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/16-300x75.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/16-768x191.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/16-680x169.png 680w\" sizes=\"(max-width: 702px) 100vw, 702px\" \/><\/a><\/p>\n<p>2010\u5e74\uff0cS. Darse\u901a\u8fc7\u66f4\u5ec9\u4ef7\u7684\u4e09\u6c2f\u5316\u948c\u6c34\u5408\u7269\uff0c\u4f7f\u82b3\u916eC-H\u952e\u70f7\u57fa\u5316\u7684\u53cd\u5e94\u6761\u4ef6\u66f4\u52a0\u6e29\u548c\u3002\u540c\u65f6\uff0c\u5177\u6709\u66f4\u4e3a\u4f18\u826f\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u53ca\u4f18\u826f\u7684\u533a\u57df\u9009\u62e9\u6027<sup>[22]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/17.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30174 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/17.png\" alt=\"\" width=\"714\" height=\"170\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/17.png 1531w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/17-300x71.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/17-768x183.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/17-680x162.png 680w\" sizes=\"(max-width: 714px) 100vw, 714px\" \/><\/a><\/p>\n<p>\u4e4b\u540e\uff0cS. Darse\u53d1\u73b0\u91c7\u7528\u8d28\u5b50\u6eb6\u5242\u5982\u5f02\u4e19\u9187\uff0c\u53ef\u4ee5\u4f7f\u53cd\u5e94\u6e29\u5ea6\u8fdb\u4e00\u6b65\u964d\u4f4e\uff0c\u540c\u65f6\u53ef\u4fdd\u6301\u4f18\u826f\u7684\u4ea7\u7387\u53ca\u533a\u57df\u9009\u62e9\u6027<sup>[23]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/18.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30175 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/18.png\" alt=\"\" width=\"777\" height=\"107\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/18.png 1522w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/18-300x41.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/18-768x105.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/18-680x93.png 680w\" sizes=\"(max-width: 777px) 100vw, 777px\" \/><\/a><\/p>\n<p>Murai-Chatani-Kakiuch\u53cd\u5e94\u5177\u6709\u4f18\u826f\u7684\u4ea7\u7387\u3001\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u4e0e\u533a\u57df\u9009\u62e9\u6027\u53ca\u6e29\u548c\u7684\u53cd\u5e94\u6761\u4ef6\u3002\u76ee\u524d\uff0c\u8be5\u53cd\u5e94\u5df2\u6210\u4e3asp<sup> 2<\/sup> C-H\u952e\u5b98\u80fd\u56e2\u5316\u7684\u5f3a\u6709\u529b\u65b9\u6cd5<sup>[24]-[27]<\/sup>\u3002<\/p>\n<h4><strong>\u57fa\u672c\u6587\u732e<\/strong><\/h4>\n<ul style=\"list-style-type: disc\">\n<li>[1] S. 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Soc<\/em>. <strong>2010<\/strong>, <em>132<\/em>, 17741. doi: <a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja104918f\">10.1021\/ja104918f.<\/a><\/li>\n<\/ul>\n<h4><strong>\u53cd\u5e94\u5b9e\u4f8b<\/strong><\/h4>\n<p>\u82b3\u916e\u4e0e\u4e9a\u80fa\u7684\u5b98\u80fd\u56e2\u5316<sup>[1]<\/sup><\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/20.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-30177 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/20.png\" alt=\"\" width=\"761\" height=\"309\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/20.png 1250w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/20-300x122.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/20-768x312.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/02\/20-680x276.png 680w\" sizes=\"(max-width: 761px) 100vw, 761px\" 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\/><\/a><\/p>\n<h4><strong>\u5b9e\u9a8c\u6b65\u9aa4<\/strong><\/h4>\n<p>\u6c2e\u6c14\u6c14\u6c1b\u4e0b\uff0c\u5411\u5706\u5e95\u70e7\u74f6\u4e2d\u52a0\u5165\u948c\u50ac\u5316\u5242 (0.02 eq.)\uff0c\u968f\u540e\uff0c\u52a0\u5165\u65e0\u6c34\u7532\u82ef (\u7ef4\u6301\u5e95\u7269\u6d53\u5ea60.67 M)\u3001\u82b3\u916e (1 eq.)\u53ca\u4e09\u4e59\u6c27\u57fa\u4e59\u70ef\u57fa\u7845\u70f7 (1 eq.)\u3002\u5c06\u4e0a\u8ff0\u53cd\u5e94\u6df7\u5408\u7269\u5728135<sup>o<\/sup>C\u4e0b\u8fdb\u884c\u52a0\u70ed (\u56de\u6d41)\u6405\u62cc\uff0c\u901a\u8fc7GC\u76d1\u63a7 (\u5341\u516d\u70f7\u4f5c\u4e3a\u5185\u6807\u7269)\uff0c\u76f4\u81f3\u53cd\u5e94\u7ed3\u675f\u3002\u53cd\u5e94\u7ed3\u675f\u540e\uff0c\u5c06\u53cd\u5e94\u6df7\u5408\u7269\u51b7\u5374\u81f3\u5ba4\u6e29\uff0c\u5e76\u5728\u51cf\u538b\u6761\u4ef6\u4e0b\u9664\u53bb\u6eb6\u5242\u3002\u6b8b\u4f59\u7269\u901a\u8fc7\u77ed\u7845\u80f6\u67f1\uff0c\u52a0\u5165\u6b63\u5df1\u70f7\u6d17\u6da4\u9664\u53bb\u5341\u516d\u70f7\u53ca\u81a6\u914d\u4f53\u5982\u4e09\u82ef\u57fa\u81a6(\u6e90\u81ea\u948c\u50ac\u5316\u5242)\u3002\u968f\u540e\uff0c\u52a0\u5165\u4e59\u9178\u4e59\u916f\u6d17\u8131\uff0c\u5c06\u6d17\u8131\u6db2\u5408\u5e76\uff0c\u51cf\u538b\u9664\u53bb\u6eb6\u5242\u540e\uff0c\u901a\u8fc7Kugelrohr\u84b8\u998f\u7684\u65b9\u5f0f\u8fdb\u884c\u5206\u79bb\u7eaf\u5316\u83b7\u5f97\u76f8\u5e94\u76ee\u6807\u4ea7\u7269\u3002<\/p>\n<h4><strong>\u53c2\u8003\u6587\u732e<\/strong><\/h4>\n<ul style=\"list-style-type: circle\">\n<li>[1] F. Kakiuchi, T. Sato, T. Tsujimoto, M. Yamauchi, N. Chatani, S. Murai, <em>Chem. Lett.<\/em> <strong>1998<\/strong>, <em>27<\/em>, 1053. doi: <a href=\"https:\/\/doi.org\/10.1246\/cl.1998.1053\">10.1246\/cl.1998.1053<\/a>.<\/li>\n<li>[2] M. O. Simon, G. Ung, S. Darses, <em>Adv. Synth. Catal.<\/em> <strong>2011<\/strong>, <em>353<\/em>, 1045. doi: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adsc.201000884\">10.1002\/adsc.201000884.<\/a><\/li>\n<li>[3] R. Grigg, V. Savic, <em>Tetrahedron Lett.<\/em> <strong>1997<\/strong>, <em>38<\/em>, 5737. doi: <a href=\"https:\/\/doi.org\/10.1016\/S0040-4039(97)01260-4\">10.1016\/S0040-4039(97)01260-4<\/a>.<\/li>\n<li>[4] M. Sonoda, F. Kakiuchi, A. Kamatani, N. Chatani, S. Murai, <em>Chem. Lett<\/em>. <strong>1996<\/strong>, 109. doi: <a href=\"https:\/\/doi.org\/10.1246\/cl.1996.109\">10.1246\/cl.1996.109<\/a>.<\/li>\n<li>[5] G. Halbritter, F. Knoch, A. Wolski, H. Kisch, <em>Angew. Chem. Int. Ed<\/em>. <strong>1994<\/strong>, <em>33<\/em>, 1603. doi:<a href=\"http:\/\/doi.wiley.com\/10.1002\/anie.199416031\"> 10.1002\/anie.199416031.<\/a><\/li>\n<li>[6] U. R. Aulwurm, J. U. Melchinger, H. Kisch, <em>Organometallics<\/em> <strong>1995<\/strong>, <em>14<\/em>, 3385. doi: <a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/om00007a045\">10.1021\/om00007a045.<\/a><\/li>\n<li>[7] U. D\u00fcrr, H. Kisch, <em>Synlett<\/em> <strong>1997<\/strong>, 1335. doi: <a href=\"https:\/\/www.thieme-connect.com\/products\/ejournals\/abstract\/10.1055\/s-1997-1035\">10.1055\/s-1997-1035.<\/a><\/li>\n<\/ul>\n<p>\u672c\u6587\u7248\u6743\u5c5e\u4e8e<strong>\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c<\/strong>\u00a0\u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"\u6982\u8981 Murai-Chatani-Kakiuchi\u53cd\u5e94 (Murai-Chatani-Kakiuchi Reaction)\u662f\u948c\u50ac\u5316\u5242 (Ru3(CO)12, RuH2(CO)(PPh3)3\u53ca[Ru(p-cymene)Cl2] 2\u7b49)\u53c2\u4e0e\u7684\u90bb\u4f4d\u5bfc\u5411C-H\u952e\u6d3b\u5316\/\u5b98\u80fd\u56e2\u5316\u53cd\u5e94 (ortho-directed C-H bond activation\/functionalization reaction) [1]\u3002\u8be5\u53cd\u5e94\u7531\u65e5\u672c\u5927\u962a\u5927\u5b66 (\u5927\u962a\u5927\u5b66\uff0cOsaka university)\u7684\u6751\u4e95\u771f\u4e8c (\u6751\u4e95 \u771f\u4e8c\uff0cMurai Shinji)\u3001 \u8336\u8c37\u76f4\u4eba (\u8336\u8c37 \u76f4\u4eba\uff0c Chatani Naoto)\u53ca\u57a3\u5185\u53f2\u654f (\u57a3\u5185 \u53f2\u654f\uff0cKakiuchi Fumishito) \u7b49\u57281993\u5e74\u9996\u6b21\u62a5\u9053\uff0cMurai-Chatani-Kakiuchi\u4e3a\u9996\u4f8b\u901a\u8fc7\u87af\u5408\u8f85\u52a9\uff0c\u5373\u901a\u8fc7\u5bfc\u5411\u57fa\u4fc3\u8fdb\u7684\u82b3\u9999\u916e\u53ca\u6742\u82b3\u9999\u916e\u7c7b\u5316\u5408\u7269\u4e0e\u70ef\u70c3\u4e4b\u95f4\u7684\u533a\u57df\u9009\u62e9\u6027\u82b3\u57faC-H\u952e\u5b98\u80fd\u56e2\u5316\u53cd\u5e94[1]\u3002 1995\u5e74\uff0cMurai\u7814\u7a76\u7ec4\u5bf9\u82b3\u9999\u916e\u53ca\u70ef\u70c3\u5e95\u7269\u7684\u5e94\u7528\u8303\u56f4\u8fdb\u884c\u4e86\u6df1\u5165\u7814\u7a76[2]\uff0c\u5e76\u5c06\u5e95\u7269\u8303\u56f4\u6269\u5c55\u81f3\u73af\u72b6\u5171\u8f6d\u70ef\u916e[3]\u3002 1996\u5e74\uff0cMurai\u91c7\u7528Ru3(CO)12\u50ac\u5316\u5242\uff0c\u5c06\u5e95\u7269\u6269\u5c55\u81f3\u82b3\u4e9a\u80fa\uff0c\u5e76\u83b7\u5f97\u4f18\u826f\u7684\u4ea7\u7387\u53ca\u533a\u57df\u9009\u62e9\u6027[4]\u3002 1997\u5e74\uff0cMurai\u7ee7\u7eed\u91c7\u7528Ru3(CO)12\u50ac\u5316\u5242\uff0c\u6210\u529f\u5b8c\u6210\u4e86\u82ef\u73afC-H\u952e\u7684\u7fb0\u57fa\u5316[5]\u3002 1997\u5e74\uff0cMurai\u91c7\u7528RuH2(CO)(PPh3)3\u50ac\u5316\u5242\uff0c\u6210\u529f\u5b8c\u6210\u975e\u73af\u5171\u8f6d\u70ef\u916e\u70ef\u57faC-H\u952e\u7684\u5b98\u80fd\u56e2\u5316\u53cd\u5e94\uff0c\u540c\u65f6\u5bf9\u53cd\u5e94\u673a\u7406\u8fdb\u884c\u4e86\u7814\u7a76[6]\u3002 \u968f\u540e\uff0cMurai\u7814\u7a76\u53d1\u73b0\uff0c\u91c7\u7528\u4e0d\u540c\u7684\u948c\u50ac\u5316\u5242\uff0c\u53ef\u4ee5\u6709\u6548\u5730\u8c03\u63a7\u82b3\u57fa\u5e95\u7269C-H\u952e\u70f7\u57fa\u5316\u8fc7\u7a0b\u7684\u533a\u57df\u9009\u62e9\u6027\uff0c\u540c\u65f6\u8fd8\u53ef\u83b7\u5f97\u6781\u4f73\u7684\u50ac\u5316\u5242\u4e13\u4e00\u6027[7]\u3002 1999\u5e74\uff0cMurai\u7b49\u53d1\u73b0\u82b3\u57fa\u8148\u5728RuH2(CO)(PPh3)3\u50ac\u5316\u5242\u5b58\u5728\u7684\u6761\u4ef6\u4e0b\uff0c\u540c\u6837\u53ef\u4ee5\u5b8c\u6210\u4e0e\u70ef\u70c3\u7684\u533a\u57df\u9009\u62e9\u6027\u82b3\u57faC-H\u952e\u70f7\u57fa\u5316\u53cd\u5e94[8], [12]\u3002 \u540c\u5e74\uff0cMurai\u7814\u7a76\u7ec4\u8fdb\u4e00\u6b65\u5b8c\u6210\u4e86\u82b3\u57fa\u9170\u4e9a\u80fa\u916f\u7684C-H\u952e\u70ef\u57fa\u5316\u53cd\u5e94[9], [12]\u3002 2001\u5e74\uff0cMurai\u7b49\u8fdb\u4e00\u6b65\u5c06\u53cd\u5e94\u5e95\u7269\u6269\u5c55\u81f3\u82b3\u9999\u919b[10]\u4e0e\u73af\u72b6\u5171\u8f6d\u70ef\u919b[10]\u53ca\u82b3\u8159[11], [12]\uff0c\u5e76\u83b7\u5f97\u4f18\u826f\u7684\u4ea7\u7387\u4e0e\u533a\u57df\u9009\u62e9\u6027[10]\u3002 2002\u5e74\uff0cMurai\u5b8c\u6210\u4e86\u948c\u50ac\u5316\u5242\u4fc3\u8fdb\u7684\u7094\u70c3\u5bf9\u5171\u8f6d\u70ef\u916eC-H\u952e\u7684\u5b98\u80fd\u56e2\u5316\u53cd\u5e94\uff0c\u6210\u529f\u83b7\u5f97\u5171\u8f6d\u4e8c\u70ef\u916e\uff0c\u53cd\u5e94\u5177\u6709\u4f18\u826f\u7684\u533a\u57df\u53ca\u7acb\u4f53\u9009\u62e9\u6027[13]\u3002 2003\u5e74\uff0cKakiuchi\u91c7\u7528\u948c\u50ac\u5316\u5242\uff0c\u987a\u5229\u5b9e\u73b0\u4e86\u82b3\u9999\u787c\u9178\u916f\u5bf9\u82b3\u916eC-H\u952e\u7684\u5b98\u80fd\u56e2\u5316\u8fc7\u7a0b\uff0c\u5e76\u53d6\u5f97\u826f\u597d\u7684\u533a\u57df\u9009\u62e9\u6027[14]\u3002\u4e4b\u540e\uff0cKakiuchi\u5bf9\u5e95\u7269\u8303\u56f4\u53ca\u53cd\u5e94\u673a\u7406\u8fdb\u884c\u4e86\u6df1\u5165\u7814\u7a76[15]\u30022007\u5e74\uff0cKakiuchi\u53c8\u5c06\u5176\u6269\u5c55\u81f3\u70ef\u57fa\u787c\u9178\u916f[16]\uff0c\u987a\u5229\u5b8c\u6210\u82b3\u916eC-H\u952e\u7684\u533a\u57df\u9009\u62e9\u6027\u70ef\u57fa\u5316\u30022010\u5e74\uff0cKakiuchi\u901a\u8fc7\u8fdb\u4e00\u6b65\u7814\u7a76\u53d1\u73b0\uff0c\u52a0\u5165\u82ef\u4e59\u70ef\u53ef\u4ee5\u6709\u6548\u5730\u63a7\u5236\u8be5\u53cd\u5e94\u7684\u533a\u57df\u9009\u62e9\u6027[17]\u3002 2006\u5e74\uff0cS. Darses\u4e0eJ. P. Genet\u91c7\u7528\u6d3b\u6027\u66f4\u9ad8\u7684[Ru(p-cymene)Cl2] 2\u50ac\u5316\u5242\uff0c\u4f7f\u53cd\u5e94\u4ea7\u7387\u4e0e\u533a\u57df\u9009\u62e9\u6027\u83b7\u5f97\u6781\u5927\u63d0\u5347[18]\u3002 2008-2009\u5e74\uff0cS. Darses\u4e0eJ. P. Genet\u91c7\u7528\u539f\u4f4d\u751f\u6210\u7684[Ru(p-cymene)Cl2] 2\u50ac\u5316\u5242\uff0c\u6210\u529f\u5c06[Ru(p-cymene)Cl2]2\u50ac\u5316\u4e0b\u7684\u5e95\u7269\u8303\u56f4\u6269\u5c55\u81f3\u82ef\u4e59\u70ef\uff0c\u540c\u6837\u53ef\u83b7\u5f97\u4f18\u826f\u7684\u533a\u57df\u9009\u62e9\u6027[19]-[20]\u3002 2009\u5e74\uff0cS. Darses\u4e0eJ. P. Genet\u5c06[Ru(p-cymene)Cl2] 2\u50ac\u5316\u7684\u53cd\u5e94\u6761\u4ef6\u6210\u529f\u6269\u5c55\u81f3\u5404\u7c7bMichael\u52a0\u6210\u53d7\u4f53\uff0c\u540c\u65f6\u83b7\u5f97\u4f18\u826f\u7684\u4ea7\u7387\u53ca\u4f18\u826f\u7684Michael\u53d7\u4f53\u03b2-\u533a\u57df\u9009\u62e9\u6027[21]\u3002 2010\u5e74\uff0cS. Darse\u901a\u8fc7\u66f4\u5ec9\u4ef7\u7684\u4e09\u6c2f\u5316\u948c\u6c34\u5408\u7269\uff0c\u4f7f\u82b3\u916eC-H\u952e\u70f7\u57fa\u5316\u7684\u53cd\u5e94\u6761\u4ef6\u66f4\u52a0\u6e29\u548c\u3002\u540c\u65f6\uff0c\u5177\u6709\u66f4\u4e3a\u4f18\u826f\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u53ca\u4f18\u826f\u7684\u533a\u57df\u9009\u62e9\u6027[22]\u3002 \u4e4b\u540e\uff0cS. Darse\u53d1\u73b0\u91c7\u7528\u8d28\u5b50\u6eb6\u5242\u5982\u5f02\u4e19\u9187\uff0c\u53ef\u4ee5\u4f7f\u53cd\u5e94\u6e29\u5ea6\u8fdb\u4e00\u6b65\u964d\u4f4e\uff0c\u540c\u65f6\u53ef\u4fdd\u6301\u4f18\u826f\u7684\u4ea7\u7387\u53ca\u533a\u57df\u9009\u62e9\u6027[23]\u3002 Murai-Chatani-Kakiuch\u53cd\u5e94\u5177\u6709\u4f18\u826f\u7684\u4ea7\u7387\u3001\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u4e0e\u533a\u57df\u9009\u62e9\u6027\u53ca\u6e29\u548c\u7684\u53cd\u5e94\u6761\u4ef6\u3002\u76ee\u524d\uff0c\u8be5\u53cd\u5e94\u5df2\u6210\u4e3asp 2 C-H\u952e\u5b98\u80fd\u56e2\u5316\u7684\u5f3a\u6709\u529b\u65b9\u6cd5[24]-[27]\u3002 \u57fa\u672c\u6587\u732e [1] S. Murai, F. Kakiuchi, S. Sekine, Y. Tanaka, A. Kamatani, M.Sonoda, N. Chatani, Nature 1993, 366, 529. doi: 10.1038\/366529a0. [2] F. Kakiuchi, S. Sekine, Y. Tanaka, A. Kamatani, M. Sonoda, N. Chatani, S. Murai, Bull. Chem. Soc. Jpn. 1995, 68, 62. doi: 10.1246\/bcsj.68.62. [3] F. 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