{"id":31461,"date":"2020-06-02T08:00:44","date_gmt":"2020-06-02T00:00:44","guid":{"rendered":"\/\/www.gsbet888.com\/?p=31461"},"modified":"2020-05-26T06:19:14","modified_gmt":"2020-05-25T22:19:14","slug":"%e5%a4%a7%e5%ae%ae-%e5%af%9b%e4%b9%85-hirohisa-ohmiya","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/chemists\/%e4%b8%96%e7%95%8c%e9%9d%92%e5%b9%b4%e5%8c%96%e5%ad%a6%e5%ae%b6\/2020\/06\/%e5%a4%a7%e5%ae%ae-%e5%af%9b%e4%b9%85-hirohisa-ohmiya.html","title":{"rendered":"\u5927\u5bae \u5bdb\u4e45 Hirohisa Ohmiya"},"content":{"rendered":"<p>\u672c\u6587\u4f5c\u8005\uff1aalberto-caeiro<\/p>\n<p>\u5927\u5bae \u5bdb\u4e45<sup>[1]<\/sup>\uff08Hirohisa Ohmiya\uff09\uff0c\u65e5\u672c\u6709\u673a\u5316\u5b66\u5bb6\uff0c\u91d1\u6ca2\u5927\u5b66\u533b\u85ac\u4fdd\u5065\u7814\u7a76\u57df\uff0c\u85ac\u5b66\u7cfb\u6559\u6388\u3002\u56fe\u7247\uff1a<a href=\"http:\/\/seimitsu.w3.kanazawa-u.ac.jp\/member\/\">\u5b9e\u9a8c\u5ba4\u4ecb\u7ecd<\/a>\u3002<\/p>\n<h4><strong>\u7ecf\u5386<\/strong><\/h4>\n<ul>\n<li>2002 B. S., Kyoto Pharmaceutical University\uff08\u4eac\u90fd\u836f\u79d1\u5927\u5b66\uff09<\/li>\n<li>2004 M. S., Kyoto Pharmaceutical University (Prof. \u4e0a\u897f\u6f64\u4e00 Jun&#8217;ichi Uenishi)<\/li>\n<li>2007 Dr degree in Engineering, Kyoto University \uff08\u4eac\u90fd\u5927\u5b66\uff09(Prof. \u5927\u5d8c\u5e78\u4e00\u90ce Koichiro Oshima)08<\/li>\n<li>2007 Postdoctoral fellow, Massachusetts Institute of Technology\uff08Prof. Timothy F. Jamison\uff09<\/li>\n<li>2008 Assistant Professor, Hokkaido University \uff08\u5317\u6d77\u9053\u5927\u5b66\uff09(Prof. \u6fa4\u6751\u6b63\u4e5f <a href=\"\/\/www.gsbet888.com\/chemists\/2019\/10\/%e4%b8%96%e7%95%8c%e8%91%97%e5%90%8d%e5%8c%96%e5%ad%a6%e5%ae%b6-masaya-sawamura.html\">Masaya Sawamura<\/a>)<\/li>\n<li>2010 Associate Professor, Hokkaido University (Prof. \u6fa4\u6751\u6b63\u4e5f Masaya Sawamura)<\/li>\n<li>2017 Professor, Kanazawa University<\/li>\n<li>2019 JST PRESTO Researcher<\/li>\n<\/ul>\n<h4><strong>\u83b7\u5956\u7ecf\u5386<\/strong><\/h4>\n<ul>\n<li>2011 The Young Scholar Lectures of The Chemical Society of Japan<\/li>\n<li>2012 The Encouragement Award from Hokkaido Branch of the Chemical Society of Japan<\/li>\n<li>2012 Hokkaido University President&#8217;s Award for Outstanding Research<\/li>\n<li>2014 The Chemical Society of Japan Award for Young Chemists<\/li>\n<li>2014 Banyu Chemist Award \u201cBCA 2014\u201d<\/li>\n<li>2014 Hokkaido University Excellent Teachers<\/li>\n<li>2015 Thieme Chemistry Journal Award 2015<\/li>\n<li>2015 Chugai Award Synthetic Organic Chemistry, Japan<\/li>\n<li>2015 Hokkaido University President&#8217;s Award for Outstanding Education<\/li>\n<li>2015 Hokkaido University President&#8217;s Award for Outstanding Research<\/li>\n<li>2015 The Young Scientists\u2019 Prize, The Commendation for Science and Technology by MEXT<\/li>\n<li>2018 Asian Core Program Lectureship Award\uff08China\uff09<\/li>\n<li>2018 Asian Core Program Lectureship Award\uff08Korea\uff09<\/li>\n<li>2019 Asian Core Program Lectureship Award\uff08Singapore\uff09<\/li>\n<\/ul>\n<h4><strong>\u5de5\u4f5c\u4ecb\u7ecd<\/strong><\/h4>\n<p><span style=\"color: #0000ff;\"><strong><em>1. N<\/em><\/strong><strong><em>&#8211;<\/em><\/strong><strong><em>h<\/em><\/strong><strong><em>eterocyclic<\/em><\/strong><strong><em> carbene-<\/em><\/strong><strong><em>based<\/em><\/strong><strong><em> (radical) organocatalys<\/em><\/strong><strong><em>is<\/em><\/strong><\/span><\/p>\n<p>Ohmiya\u6559\u6388\u5c06NHC\u50ac\u5316\u53cd\u5e94\u548c\u91d1\u5c5e\u50ac\u5316\u7684\u70ef\u4e19\u57fa\u53d6\u4ee3\u53cd\u5e94\u7ed3\u5408\uff0c\u5e95\u7269\u919b\u4e0e\u5c0f\u5206\u5b50\u50ac\u5316\u5242NHC\u53cd\u5e94\u751f\u6210\u7684Breslow\u4e2d\u95f4\u4f53\u4e0e\u70ef\u4e19\u57fa\u91d1\u5c5e\u590d\u5408\u7269\u53d1\u751f\u70ef\u4e19\u57fa\u53d6\u4ee3\u53cd\u5e94\uff0c\u5f97\u5230\u03b2,\u03b3-\u4e0d\u9971\u548c\u916e\u7c7b\u5316\u5408\u7269<sup>[2]<\/sup>\u3002<\/p>\n<p>\u800c\u5728\u81ea\u7531\u57fa\u8fc7\u7a0b\u4e2d\uff0c\u751f\u6210\u7684Breslow\u4e2d\u95f4\u4f53\u53bb\u8d28\u5b50\u540e\uff0c\u4e0e\u90bb\u82ef\u4e8c\u7532\u9170\u4e9a\u80fa\u916f\u53d1\u751f\u7535\u5b50\u8f6c\u79fb\uff0c\u751f\u6210\u6b63\u79bb\u5b50\u81ea\u7531\u57fa\u4e0e\u8131\u7fa7\u540e\u751f\u6210\u7684\u70f7\u57fa\u81ea\u7531\u57fa\u7ed3\u5408\u5f97\u5230\u539f\u6599\u919b\u70f7\u57fa\u5316\u7684\u916e\u4ea7\u7269<sup>[3a]<\/sup>\u3002\u6b64\u5916\uff0c\u8be5\u53cd\u5e94\u4f53\u7cfb\u4e2d\u53ef\u52a0\u5165\u70ef\u70c3\uff0c\u5f97\u5230\u63d2\u70ef\u70f7\u57fa\u5316\u4ea7\u7269<sup>[3b]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/1-12.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-31462 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/1-12.jpg\" alt=\"\" width=\"642\" height=\"419\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/1-12.jpg 748w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/1-12-300x196.jpg 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/1-12-680x444.jpg 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/1-12-260x170.jpg 260w\" sizes=\"(max-width: 642px) 100vw, 642px\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><em>NHC-based (radical) organocatalysis<\/em><\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/2-10.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-31463 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/2-10.jpg\" alt=\"\" width=\"585\" height=\"246\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/2-10.jpg 679w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/2-10-300x126.jpg 300w\" sizes=\"(max-width: 585px) 100vw, 585px\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><em>Reaction mechanisms: left: NHC\/Pd hybrid catalysis; right: NHC radical catalysis<\/em><\/p>\n<p><span style=\"color: #0000ff;\"><strong><em>2. Reductive umpolung of aldehydes <\/em><\/strong><\/span><\/p>\n<p>Ohmiya\u6559\u6388\u5c06\u7845\u57fa\u94dc\u5bf9\u919b\u52a0\u6210\u53cd\u5e94\u548c[1,2]-Brook\u91cd\u6392\u53cd\u5e94\u7ed3\u5408\u8d77\u6765\uff0c\u5b9e\u73b0\u4e86\u919b\u7684\u6781\u6027\u53cd\u8f6c\uff0c\u5f62\u6210\u7684\u70f7\u57fa\u94dc\u7269\u79cd\u53ef\u76f4\u63a5\u8fdb\u653b\u916e\uff0c\u4e9a\u80fa\u751f\u6210\u624b\u6027\u90bb\u4e8c\u9187<sup>[4a]<\/sup>\u548c\u03b1-\u6c28\u57fa\u9187<sup>[4b]<\/sup>\uff0c\u4e5f\u53ef\u4e0e\u53d1\u751f\u8f6c\u91d1\u5c5e\uff0c\u5b9e\u73b0\u919b\u7684\u82b3\u57fa\u52a0\u6210\u53cd\u5e94\u5f97\u5230\u624b\u6027\u9187<sup>[4c,d]<\/sup>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/3-10.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-31464 \" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/3-10.jpg\" alt=\"\" width=\"533\" height=\"404\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/3-10.jpg 613w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/3-10-300x228.jpg 300w\" sizes=\"(max-width: 533px) 100vw, 533px\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><em>Reductive umpolung of aldehydes<\/em><\/p>\n<h4><strong>\u53c2\u8003\u6587\u732e<\/strong><\/h4>\n<ul>\n<li>[1] Ohmiya H. <em>Angew. Chem. Int. Ed.<\/em> <strong>2018<\/strong>, <em>57<\/em>, 13718. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/anie.201805108\">DOI: 10.1002\/anie.201805108<\/a>.<\/li>\n<li>[2] a. Ohmiya, H. <em>Angew. Chem. Int. Ed.<\/em> <strong>2018<\/strong>, <em>57<\/em>, 2938. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/anie.201712811\">DOI: 10.1002\/anie.201712811<\/a>; b. Ohmiya, H. <em>Chem. Eur. J.<\/em> <strong>2019<\/strong>, <em>25<\/em>, 724. <a href=\"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/chem.201805955\">DOI: 10.1002\/chem.201805955<\/a>; c. Ohmiya, H. <em>Bull. Chem Soc. Jpn.<\/em> <strong>2019<\/strong>, <em>92<\/em>, 937. <a href=\"https:\/\/www.journal.csj.jp\/doi\/abs\/10.1246\/bcsj.20190012\">DOI: 10.1246\/bcsj.20190012<\/a>.<\/li>\n<li>[3] a. Ohmiya, H. <em>J. Am. Chem. Soc.<\/em> <strong>2019<\/strong>, <em>141<\/em>, 3854. <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.9b00880\">DOI: 10.1021\/jacs.9b00880<\/a>; b. Ohmiya, H.<em> J. Am. Chem. Soc.<\/em> <strong>2019<\/strong>, <em>141<\/em>, 14073. <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.9b07194\">DOI: 10.1021\/jacs.9b07194<\/a>.<\/li>\n<li>[4] a. Ohmiya, H. <em>J. Am. Chem. Soc. <\/em><strong>2019<\/strong>, <em>141<\/em>, 3664. <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.8b13309\">DOI: 10.1021\/jacs.8b13309<\/a>; b. Ohmiya, H. <em>Org. Lett. <\/em><strong>2020<\/strong>, <em>22<\/em>, 800. <a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.orglett.9b04144\">DOI: 10.1021\/acs.orglett.9b04144<\/a>; c. Ohmiya, H. <em>J. Am. Chem. Soc.<\/em> <strong>2019<\/strong>, <em>141<\/em>, 113. <a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/jacs.8b11495\">DOI: 10.1021\/jacs.8b11495<\/a>; d. Ohmiya, H. <em>Chem. Commun. <\/em><strong>2018<\/strong>, <em>54<\/em>, 6776. <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2018\/cc\/c8cc01055b#!divAbstract\">DOI: 10.1039\/c8cc01055b<\/a>.<\/li>\n<\/ul>\n<p>\u672c\u6587\u7248\u6743\u5c5e\u4e8e<strong>\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c<\/strong>\u00a0\u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"\u672c\u6587\u4f5c\u8005\uff1aalberto-caeiro \u5927\u5bae \u5bdb\u4e45[1]\uff08Hirohisa Ohmiya\uff09\uff0c\u65e5\u672c\u6709\u673a\u5316\u5b66\u5bb6\uff0c\u91d1\u6ca2\u5927\u5b66\u533b\u85ac\u4fdd\u5065\u7814\u7a76\u57df\uff0c\u85ac\u5b66\u7cfb\u6559\u6388\u3002\u56fe\u7247\uff1a\u5b9e\u9a8c\u5ba4\u4ecb\u7ecd\u3002 \u7ecf\u5386 2002 B. S., Kyoto Pharmaceutical University\uff08\u4eac\u90fd\u836f\u79d1\u5927\u5b66\uff09 2004 M. S., Kyoto Pharmaceutical University (Prof. \u4e0a\u897f\u6f64\u4e00 Jun&#8217;ichi Uenishi) 2007 Dr degree in Engineering, Kyoto University \uff08\u4eac\u90fd\u5927\u5b66\uff09(Prof. \u5927\u5d8c\u5e78\u4e00\u90ce Koichiro Oshima)08 2007 Postdoctoral fellow, Massachusetts Institute of Technology\uff08Prof. Timothy F. Jamison\uff09 2008 Assistant Professor, Hokkaido University \uff08\u5317\u6d77\u9053\u5927\u5b66\uff09(Prof. \u6fa4\u6751\u6b63\u4e5f Masaya Sawamura) 2010 Associate Professor, Hokkaido University (Prof. \u6fa4\u6751\u6b63\u4e5f Masaya Sawamura) 2017 Professor, Kanazawa University 2019 JST PRESTO Researcher \u83b7\u5956\u7ecf\u5386 2011 The Young Scholar Lectures of The Chemical Society of Japan 2012 The Encouragement Award from Hokkaido Branch of the Chemical Society of Japan 2012 Hokkaido University President&#8217;s Award for Outstanding Research 2014 The Chemical Society of Japan Award for Young [&hellip;]","protected":false},"author":26,"featured_media":31465,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2577],"tags":[2575,2576,2574],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/04\/F-9.jpg","jetpack_shortlink":"https:\/\/wp.me\/p96op1-8br","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/31461"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/26"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=31461"}],"version-history":[{"count":3,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/31461\/revisions"}],"predecessor-version":[{"id":32459,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/31461\/revisions\/32459"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/31465"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=31461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=31461"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=31461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}