{"id":31785,"date":"2020-05-25T08:00:54","date_gmt":"2020-05-25T00:00:54","guid":{"rendered":"\/\/www.gsbet888.com\/?p=31785"},"modified":"2020-05-21T21:49:30","modified_gmt":"2020-05-21T13:49:30","slug":"corinna-s-schindler","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/chemists\/%e4%b8%96%e7%95%8c%e9%9d%92%e5%b9%b4%e5%8c%96%e5%ad%a6%e5%ae%b6\/2020\/05\/corinna-s-schindler.html","title":{"rendered":"Corinna S. Schindler"},"content":{"rendered":"
\u672c\u6587\u4f5c\u8005\uff1a\u77f3\u6cb9\u919a<\/p>\n
Corinna S. Schindler, \u5728\u5fb7\u56fd\u65bd\u97e6\u6bd4\u65bd\u54c8\u5c14\u51fa\u751f\u5e76\u957f\u5927\uff0c\u7f8e\u56fd\u5bc6\u6b47\u6839\u5927\u5b66\u79d1\u5b66\u4e0e\u827a\u672f\u5b66\u9662\u52a9\u7406\u6559\u6388\uff0c\u6709\u673a\u5316\u5b66\u5bb6\u3002<\/p>\n
\u8bfe\u9898\u7ec4\u4e3b\u9875\uff1ahttps:\/\/www.schindlerresearchgroup.com\/<\/a><\/p>\n Corinna S. Schindler\u4e3b\u8981\u7814\u7a76\u5ec9\u4ef7\u6613\u5f97\u7684\u91d1\u5c5eFe\u50ac\u5316\u7fb0\u57fa\u5316\u7269-\u70ef\u70c3\u7684\u590d\u5206\u89e3\u53cd\u5e94\uff0c\u5177\u6709\u751f\u7269\u6d3b\u6027\u7684\u5929\u7136\u4ea7\u7269\u7684\u5168\u5408\u6210\u3002\u8bfe\u9898\u7ec4\u7684\u7406\u5ff5\u662f\u201c\u5408\u6210\u4e0e\u50ac\u5316\u201d\uff0c\u53d1\u5c55\u65b0\u7684\u53cd\u5e94\u5e76\u5e94\u7528\u4e8e\u9ad8\u6d3b\u6027\u7684\u5929\u7136\u4ea7\u7269\u7684\u5168\u5408\u6210\uff0c\u505a\u6709\u7528\u7684\u5316\u5b66\u3002<\/p>\n 1. Fe<\/strong>\u50ac\u5316\u7684\u7fb0\u57fa<\/strong>–<\/strong>\u70ef\u70c3\u590d\u5206\u89e3<\/strong>1-10<\/sup><\/strong><\/span><\/p>\n \u70ef\u70c3\u590d\u5206\u89e3\u53cd\u5e94\u662f\u8fc4\u4eca\u4e3a\u6b62\u5df2\u77e5\u7684\u6700\u5f3a\u5927\u7684\u78b3-\u78b3\u952e\u5f62\u6210\u7684\u53cd\u5e94\u4e4b\u4e00\uff0c\u901a\u8fc7\u7b80\u5355\u7684\u8f6c\u5316\u5c31\u53ef\u4ee5\u4ece\u7b80\u5355\u7684\u70ef\u70c3\u524d\u4f53\u5408\u6210\u590d\u6742\u7684\u4e0d\u9971\u548c\u70ef\u70c3\u3002\u867d\u7136\u7fb0\u57fa-\u70ef\u70c3\u590d\u5206\u89e3\u5c5e\u4e8e\u5176\u4e2d\uff0c\u4f46\u662f\u4ee5\u5f80\u5b9e\u73b0\u8fd9\u4e00\u8fc7\u7a0b\u9700\u8981\u5b9e\u73b0\u5316\u5b66\u8ba1\u91cf\u7684Mo(IV)\u8fc7\u6e21\u91d1\u5c5e\u7edc\u5408\u7269\u4ee5\u53ca\u4e25\u82db\u7684\u5b9e\u9a8c\u6761\u4ef6\u4e25\u91cd\u963b\u788d\u7fb0\u57fa-\u70ef\u70c3\u590d\u5206\u89e3\u53cd\u5e94\u5f97\u8fdb\u7a0b\u3002Schindler\u5c0f\u7ec4\u4f7f\u7528\u5ec9\u4ef7\u6613\u5f97\uff0c\u73af\u5883\u53cb\u597d\u4ee5\u53ca\u50ac\u5316\u91cf\u7684FeCl3<\/sub>\u66ff\u4ee3\u5316\u5b66\u8ba1\u91cf\u7684\u8d35\u91d1\u5c5e\u50ac\u5316\u5242\uff0c\u5728\u7fb0\u57fa-\u70ef\u70c3\u590d\u5206\u89e3\u65b9\u9762\u53d6\u5f97\u8fc8\u51fa\u4e86\u91cd\u8981\u4e00\u6b651<\/sup>\u3002\u8bfe\u9898\u7ec4\u57fa\u4e8eFe\u50ac\u5316\u7684\u7fb0\u57fa-\u70ef\u70c3\u590d\u5206\u89e3\u53cd\u5e94\u5b9e\u73b0\u4e86\u5206\u5b50\u95f4\uff0c\u5206\u5b50\u5185\u7684\u7fb0\u57fa-\u70ef\u70c3\u590d\u5206\u89e3\u53cd\u5e94\u6765\u6784\u5efa\u590d\u6742\u7684\u4e0d\u9971\u548c\u70c3\u5316\u5408\u7269\u3002(Fig.1)<\/p>\n Figure 1 Fe\u50ac\u5316\u7684\u7fb0\u57fa-\u70ef\u70c3\u590d\u5206\u89e3<\/p>\n \u94c1(III)\u50ac\u5316\u7684\u7fb0\u57fa-\u70ef\u70c3\u95ed\u73af\u590d\u5206\u89e3\u4ee3\u8868\u4e86\u4e00\u79cd\u7528\u4e8e\u7ec4\u88c5\u4f20\u7edf\u4e0a\u7531\u70ef\u70c3-\u70ef\u70c3\u590d\u5206\u89e3\u6216\u70ef\u70c3\u5316\u751f\u6210\u7684\u5206\u5b50\u7684\u65b0\u65b9\u6cd5\u3002Schindler\u5c0f\u7ec43<\/sup>\u901a\u8fc7\u8be6\u7ec6\u7684\u6761\u4ef6\u7b5b\u9009\uff0c\u5149\u8c31\uff0c\u52a8\u529b\u5b66\u548c\u8ba1\u7b97\u5316\u5b66\u65b9\u9762\u7684\u7814\u7a76\uff0c\u4ee5\u786e\u5b9a\u7531\u94c1(III)\u4e2d\u95f4\u4f53\u4ee5\u53ca\u6e29\u5ea6\uff0c\u6d53\u5ea6\u7b49\u65b9\u9762\u7684\u6570\u636e\u3002\u7531\u4e8e\u83b7\u5f97\u6570\u636e\uff0cSchindler\u5c0f\u7ec4\u53d1\u73b0[2 + 2]\u73af\u52a0\u6210\u53cd\u5e94\u5f62\u6210\u4e2d\u95f4\u4f53\u6c27\u6742\u73af\u4e01\u70f722<\/strong>\u662f\u51b3\u901f\u6b65\u9aa4\uff0c\u800c\u540e\u6c27\u6742\u73af\u4e01\u70f7\u901a\u8fc7\u8def\u6613\u65af\u9178\u6d3b\u5316\u4f5c\u7528\u7684\u65ad\u88c2\u5bfc\u81f4\u5f62\u6210\u4e94\u5143\u6216\u516d\u5143\u4e0d\u9971\u548c\u78b3\u73af\u3002\uff08Fig.2\uff09<\/p>\n Figure 2 Fe\u50ac\u5316\u7684\u7fb0\u57fa-\u70ef\u70c3\u590d\u5206\u89e3\u53cd\u5e94\u673a\u7406<\/p>\n 2. \u5929\u7136\u4ea7\u7269\u5168\u5408\u6210\u53ca\u5176\u6d3b\u6027\u4f5c\u7528\u7814\u7a76<\/strong><\/span><\/p>\n Schindler\u6559\u6388\u5728\u5b66\u751f\u65f6\u4ee3\u5c31\u5f00\u59cb\u4e86\u5168\u5408\u6210\u5de5\u4f5c\u7684\u63a2\u7d2211-13<\/sup>\uff0c\u5b8c\u6210\u4e86\u591a\u4e2a\u5929\u7136\u4ea7\u7269\u7684\u5168\u5408\u6210\u5de5\u4f5c\uff0c\u56e0\u6b64\u4e0e\u5929\u7136\u4ea7\u7269\u5168\u5408\u6210\u7ed3\u4e0b\u4e86\u4e0d\u89e3\u4e4b\u7f18\u3002\u81ea\u5df1\u72ec\u7acb\u5f00\u5c55\u5de5\u4f5c\u540e\uff0c\u8bfe\u9898\u7ec4\u7684\u53e6\u5916\u4e00\u4e2a\u65b9\u5411\u662f\u9ad8\u6d3b\u6027\u5929\u7136\u4ea7\u7269\u7684\u5168\u5408\u6210\u7684\u7814\u7a76\u4ee5\u53ca\u5206\u5b50\u751f\u7406\u6d3b\u6027\u8bc4\u4ef7\u3002\u76ee\u524d\u5df2\u7ecf\u5b8c\u6210\u4e86\uff1a1\uff09\u4ece\u7275\u725b\u82b1\u79cd\u5b50\u4e2d\u5206\u79bb\u51fa\u6765\u5177\u6709\u6297\u764c\u7ec6\u80de\u6bd2\u6027\u4ee5\u53ca\u5bf9\u4e8e A549\uff0cSK-OV-3\uff0cSK-MEL-2\u548cHCT-15\u7ec6\u80de\u6d3b\u6027\u7684Pharbinilic acid\u53ca\u5176\u884d\u751f\u7269\uff0c\u5e76\u4e14\u8fd8\u4f5c\u4e3aNF-k<\/em>B\u6291\u5236\u5242\u7684\u751f\u7269\u5b66\u8bc4\u4ef714<\/sup>\uff1b2\uff09\u5177\u6709\u72ec\u7279\u652f\u539f\u4f53\u73af\u7d20\u9aa8\u67b6\u7528\u6765\u4f5c\u4e3a\u5bf9\u5bbf\u4e3b\u5177\u6709\u4f4e\u6bd2\u6027\u7684\u9009\u62e9\u6027CYP121\u6291\u5236\u5242\u7684\u73af\u5b62\u83cc\u7d2015<\/sup>\uff0c3\uff09\u4ece\u620a\u9178\u9752\u9709Fg-372\u4e2d\u5206\u79bb\u51fa\u4e00\u79cd\u5177\u6709\u6291\u5236\u6d41\u611f\u75c5\u6bd2\u590d\u5236\u663e\u793a\u51fa\u6297\u751f\u7d20\u4f5c\u7528\u4ee5\u53ca\u9632\u6b62\u8840\u5c0f\u677f\u51dd\u7ed3\u7684\u5927\u73af\u771f\u83cc\u4ee3\u8c22\u7269Herquline A\u53ca\u5176\u884d\u751f\u726916<\/sup>\u3002(Fig.3)<\/p>\n Figure 2\u5929\u7136\u4ea7\u7269\u5168\u5408\u6210\u53ca\u5176\u6d3b\u6027\u4f5c\u7528\u7814\u7a76<\/p>\n \u5bf9\u4e8e\u5b66\u751f\u6765\u8bf4\uff0c\u6bd5\u4e1a\u7b54\u8fa9\u53ef\u8c13\u662f\u5b66\u751f\u751f\u6daf\u4e2d\u6700\u5f00\u5fc3\uff0c\u6700\u7d27\u5f20\u7684\u4e8b\uff0c\u5b8c\u6210\u7b54\u8fa9\u4e4b\u540e\u63a5\u8e35\u800c\u81f3\u7684\u5e94\u8be5\u662f\u805a\u4f1a\u548c\u5e86\u795d\u3002\u4f46\u662fCorinna S. Schindler\u6559\u6388\u5728\u5b8c\u6210\u7b54\u8fa9\u540e\u5374\u5bf9\u5bfc\u5e08Erick M. Carreira\u8bf4\u7b54\u8fa9\u7ed3\u675f\u540e\u8981\u5b8c\u6210\u51e0\u4e2a\u91cd\u8981\u7684\u5b9e\u9a8c\u3002Prof. Erick M. Carreira \u4ee5\u4e3aCorinna S. Schindler\u5728\u5f00\u73a9\u7b11\u3002\u4f46\u662f\u7b54\u8fa9\u7ed3\u675f\u540e\uff0cCorinna S. Schindler\u4e0d\u7ea6\u800c\u540c\u7684\u5728\u5b9e\u9a8c\u5ba4\u5fd9\u7eff\u3002<\/p>\n Prof. Erick M. Carreira<\/strong>\u5bf9\u5979\u8bc4\u4ef7\u201c<\/strong>Schindler<\/strong>\u662f\u4ed6\u89c1\u8fc7\u6700\u4e3a\u52e4\u594b\u523b\u82e6\u7684\u5b66\u751f\uff0c\u5979\u4e0d\u4ec5\u62e5\u6709\u654f\u6377\u7684\u601d\u7ef4\uff0c\u800c\u4e14\u8fd8\u4f1a\u4e3a\u81ea\u5df1\u6bcf\u5929\u7684\u5de5\u4f5c\u505a\u597d\u5468\u5bc6\u7684\u8ba1\u5212\u3002\u9762\u5bf9\u79d1\u5b66\u7814\u7a76\u4e2d\u7684\u79cd\u79cd\u56f0\u96be\u3002\u603b\u662f\u52c7\u4e8e\u9762\u5bf9\uff0c\u4ece\u4e0d\u9000\u7f29\u3002\u201d<\/em><\/strong><\/p><\/blockquote>\n\u7ecf\u5386<\/strong><\/h4>\n
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