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Wang\u7b49\u53d1\u5c55\u4e86\u7b2c\u4e00\u4f8bPd\u50ac\u5316\u7094\u70c3\u7684\u5bf9\u6620\u9009\u62e9\u6027\u6c22\u81a6\u5316\u53cd\u5e94\uff0c\u9ad8\u6548\u7684\u5236\u5907\u5177\u6709P-\u624b\u6027\u7684\u624b\u6027\u70ef\u57fa\u81a6\u9178\u916f\u3002\u76f8\u5173\u6210\u679c\u53d1\u8868\u4e8e\uff1a<\/p>\n<blockquote><p>\u201cPalladium-Catalyzed Asymmetric Hydrophosphorylation ofAlkynes: Facile Access to P\u2011StereogenicPhosphinates\u201d<\/p>\n<p>Zhiping Yang, XiaodongGu, Li-Biao Han and Jun (Joelle)<\/p>\n<p><em>Chem. Sci.<\/em>, <strong>2020<\/strong>, <em>11<\/em>, 7451-7455. DOI: <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2020\/SC\/D0SC01049A#!divAbstract\"><u>10.1039\/D0SC01049A<\/u><\/a><\/p><\/blockquote>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/1-46.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-34850 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/1-46.jpg\" alt=\"\" width=\"934\" height=\"828\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/1-46.jpg 934w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/1-46-300x266.jpg 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/1-46-680x603.jpg 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/1-46-768x681.jpg 768w\" sizes=\"(max-width: 934px) 100vw, 934px\" \/><\/a><\/p>\n<p style=\"text-align: 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\/><\/a><\/p>\n<p>\u5728\u83b7\u53d6\u6700\u4f18\u7684\u53cd\u5e94\u6761\u4ef6\u4e0b\uff0c\u4f5c\u8005\u5bf9\u5e95\u7269\u9002\u5e94\u8303\u56f4\u8fdb\u884c\u4e86\u7814\u7a76\uff08\u56fe2\uff09\u3002\u4f5c\u8005\u53d1\u73b0\u5404\u79cd\u7094\u70c3\u80fd\u5f88\u597d\u7684\u9002\u7528\u4e8e\u8be5\u53cd\u5e94\u4f53\u7cfb\u3002\u65e0\u8bba\u82b3\u57fa\u7094\u70c3\u4e0a\u5e26\u6709\u7ed9\u7535\u5b50\u57fa\u56e2\uff08MeO\u3001Me\u3001Et\u3001<em>n<\/em>-pent\u3001<em>t<\/em>Bu\uff09\uff08<strong>3ba-3ga<\/strong>\u3001<strong>3la<\/strong>\u3001<strong>3ma<\/strong>\uff09\u6216\u5438\u7535\u5b50\u57fa\u56e2\uff08Cl\u3001F\u3001Br\u3001CF<sub>3<\/sub>\uff09\uff08<strong>3ha-3ka<\/strong>\uff0c<strong>3na<\/strong>\uff09\uff0c\u5728\u95f4\u4f4d\u6216\u8005\u5bf9\u4f4d\u5747\u5c55\u73b0\u51fa\u826f\u597d\u7684\u8010\u53d7\u6027\u3002\u4f46\u662f\uff0c\u90bb\u4f4d\u7532\u57fa\u7684\u7094\u70c3\u5bf9\u5e94\u7684\u5bf9\u6620\u9009\u62e9\u6027\u964d\u4f4e\uff08<strong>3da<\/strong>\uff0c91%\uff0c30%<em>ee<\/em>\uff09\u3002\u5177\u6709-CN\u6216-NO<sub>2<\/sub>\u57fa\u56e2\u7684\u82b3\u73af\u6ca1\u6709\u5f97\u5230\u671f\u671b\u7684\u4ea7\u7269\u3002\u542b\u567b\u5429\u6216\u5421\u5576\u57fa\u56e2\u7684\u5e95\u7269\u5728\u8be5\u53cd\u5e94\u6761\u4ef6\u4e0b\u4e5f\u80fd\u5f97\u5230\u5bf9\u5e94\u7684\u4ea7\u7269<strong>3oa<\/strong>\u548c<strong>3pa<\/strong>\uff0c\u6536\u7387\u9002\u4e2d\u4e14<em>ee<\/em>\u503c\u597d\u3002\u4e8c\u82ef\u4e59\u7094\u4e5f\u6709\u4e2d\u7b49\u7684\u6536\u7387\u548c<em>ee<\/em>\uff08<strong>3qa<\/strong>\uff0c69%\uff0c61%<em>ee<\/em>\uff09\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u4e5f\u8bc1\u660e\u4e86\u8102\u80aa\u65cf\u7094\u70c3\u4e5f\u662f\u53ef\u884c\u7684\uff0c\u4ea7\u7387\u7565\u6709\u4e0b\u964d\uff0c\u4f46<em>ee<\/em>\u5747\u8f83\u9ad8\uff08<strong>3ra-3ta<\/strong>\uff09\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/3-40.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-34852 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/3-40.jpg\" alt=\"\" width=\"1282\" height=\"1726\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/3-40.jpg 1282w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/3-40-223x300.jpg 223w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/3-40-680x916.jpg 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/3-40-768x1034.jpg 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/3-40-1141x1536.jpg 1141w\" sizes=\"(max-width: 1282px) 100vw, 1282px\" \/><\/a><\/p>\n<p style=\"text-align: center;\">\u56fe2\u5e95\u7269\u62d3\u5c55\u7814\u7a76<\/p>\n<p>\u5728\u5f97\u5230\u7094\u70c3\u7684\u7814\u7a76\u7ed3\u679c\u540e\uff0c\u4f5c\u8005\u8fdb\u4e00\u6b65\u5c1d\u8bd5\u5c06\u8be5\u50ac\u5316\u4f53\u7cfb\u6269\u5c55\u5230\u4e0d\u540c\u7684\u6b21\u78f7\u9178\u916f\uff08\u56fe3\uff09\u3002\u542b\u6709\u7532\u916f\u6216\u4e19\u916f\u7684\u5e95\u7269\u4e5f\u8fdb\u884c\u4e86\u6c22\u81a6\u5316\u53cd\u5e94\uff0c\u5e76\u4ee5\u4e2d\u7b49\u6536\u7387\u548c\u5bf9\u6620\u9009\u62e9\u6027\u5f97\u5230\u76f8\u5e94\u7684\u70ef\u57fa\u81a6\u9178\u916f\uff08<strong>3ab<\/strong>\uff0c<strong>3ac<\/strong>\uff09\u3002\u542b\u6709\u5f02\u4e19\u57fa\u7684\u5e95\u7269\u5bf9\u5e94\u81a6\u9178\u916f\u7684\u6536\u7387\uff08<strong>3ad<\/strong>\uff09\u4e0b\u964d\u81f332%\uff0c\u4e14\u5bf9\u6620\u9009\u62e9\u6027\u7565\u5fae\u4e0b\u964d\u81f373%<em>ee<\/em>\u3002\u6b21\u78f7\u9178\u916f\u7684\u82b3\u73af\u4e0a\u5177\u6709\u7532\u57fa\u53d6\u4ee3\u65f6\uff0c\u53ef\u5f97\u4ea7\u7269<strong>3ae<\/strong>\uff0847%\uff0c37%<em>ee<\/em>\uff09\uff1b\u542b<em>t<\/em>Bu\u57fa\u65f6\uff0c\u53ef\u5f97\u5316\u5408\u7269<strong>3fb<\/strong>\u3002\u5f53\u6b21\u78f7\u9178\u916f\u6362\u4e3a\u7532\u57fa\u53d6\u4ee3\u7684\u6b21\u81a6\u6c27\u5316\u7269<strong>\u65f6\uff0c<\/strong>\u5728\u76f8\u4f3c\u7684\u53cd\u5e94\u6761\u4ef6\u4e0b\u4ee528%\u7684\u6536\u7387\u548c54%\u7684<em>ee<\/em>\u5f97\u5230\u4ea7\u7269<strong>3af<\/strong>\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/4-33.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-34853 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/4-33.jpg\" alt=\"\" width=\"829\" height=\"659\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/4-33.jpg 829w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/4-33-300x238.jpg 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/4-33-680x541.jpg 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/4-33-768x611.jpg 768w\" sizes=\"(max-width: 829px) 100vw, 829px\" \/><\/a><\/p>\n<p style=\"text-align: center;\">\u56fe3\u6b21\u78f7\u9178\u916f\u5e95\u7269\u62d3\u5c55\u7814\u7a76<\/p>\n<p>\u4e3a\u4e86\u8bc4\u4f30\u8be5\u50ac\u5316\u4f53\u7cfb\u7684\u5408\u6210\u6f5c\u529b\uff0c\u4f5c\u8005\u5c06\u82ef\u4e59\u7094\u4e0e\u4e59\u57fa\u82ef\u6b21\u81a6\u9178\u916f\u8fdb\u884c\u514b\u7ea7\u53cd\u5e94\u7814\u7a76\uff0c\u4ee568%\u7684\u6536\u7387\u548c82%\u7684<em>ee<\/em>\u5f97\u5230\u4ea7\u7269<strong>3aa<\/strong>\uff08\u56fe4a\uff09\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u8fd8\u5bf9\u76ee\u6807\u4ea7\u7269\u8fdb\u884c\u4e86\u8fdb\u4e00\u6b65\u5408\u6210\u8f6c\u5316\u3002\u5316\u5408\u7269<strong>4<\/strong>\u548c<strong>5<\/strong>\u901a\u8fc7Suzuki-Miyaura\u5076\u8054\u53cd\u5e94\u5236\u5907\uff0c\u4e14\u5bf9\u6620\u9009\u62e9\u6027\u4fdd\u6301\uff08\u56fe4b\uff09\u3002\u901a\u8fc7\u884d\u751f\u5316\u4ea7\u7269<strong>5<\/strong>\u53ef\u786e\u5b9a\u4ea7\u7269<strong>3ja<\/strong>\u7684\u7edd\u5bf9\u6784\u578b\u4e3a<em>R<\/em>-\u6784\u578b\u3002\u82b3\u57fa\u91cd\u6c2e\u76d0\u4e0e\u70ef\u57fa\u81a6\u9178\u916f<strong>3aa<\/strong>\u53cd\u5e94\uff0c\u53ef\u4ee5\u4f18\u5f02\u7684\u7acb\u4f53\u9009\u62e9\u6027\u5f97\u5230\u987a\u5f0f\u4e8c\u82ef\u4e59\u70ef<strong>3qa<\/strong>\uff08\u56fe4c\uff0c99%\uff0c82% 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center;\">\u56fe4\u884d\u751f\u5316\u53cd\u5e94\u7814\u7a76<\/p>\n<p>\u4e3a\u4e86\u6df1\u5165\u4e86\u89e3\u53cd\u5e94\u673a\u7406\uff0c\u4f5c\u8005\u4ee5D-P(O)(OMe)Ph\u4e3a\u8d77\u59cb\u539f\u6599\u8fdb\u884c\u6c18\u6807\u8bb0\u5b9e\u9a8c\uff0c\u5f97\u5230<strong>3ab<\/strong>\uff0842%\uff09\uff0cD<sub>1<\/sub>&#8211;<strong>3ab<\/strong>\uff0850%\uff09\u548c\u5c11\u91cf\u7684D<sub>2<\/sub>&#8211;<strong>3ab<\/strong>\uff086%\uff09\uff0c\u5176\u4e2d\u4e24\u4e2a\u6c18\u5728\u70ef\u70c3\u672b\u7aef\u7684\u78b3\u539f\u5b50\u4e0a\u7ed3\u5408\uff08\u56fe5\uff09\uff0c\u8fd9\u4e00\u7ed3\u679c\u8868\u660e\u6c27\u5316\u52a0\u6210\u3001\u52a0\u6c22\u548c\u914d\u4f53\u4ea4\u6362\u662f\u53ef\u9006\u7684\u3002\u4ee5\u6c18\u6807\u8bb0\u5b9e\u9a8c\u4e3a\u57fa\u7840\u548c\u5148\u524d\u7684\u62a5\u9053\uff0c\u4f5c\u8005\u63d0\u51fa\u4e86\u4e00\u4e2a\u53ef\u80fd\u7684\u50ac\u5316\u5faa\u73af\u3002Pd<sub>2<\/sub>(dba)<sub>3<\/sub>\u548c(<em>R<\/em>,<em>R<\/em>)-QuinoxP*\u5f62\u6210\u624b\u6027\u94af\u914d\u5408\u7269<strong>A<\/strong>\u3002\u968f\u540ePh<sub>2<\/sub>P(O)OH\u7684O-H\u952e\u4e0e\u94af\u7684\u6c27\u5316\u52a0\u6210\u53cd\u5e94\u751f\u6210\u94af\u4e2d\u95f4\u4f53<strong>B<\/strong>\u3002\u7136\u540e\u901a\u8fc7Markovnikov\u52a0\u6210\uff0c\u8fdb\u884c\u7094\u70c3\u6c22\u94af\u5316\u53cd\u5e94\uff0c\u5f97\u5230\u70ef\u57fa\u94af\u4e2d\u95f4\u4f53<strong>C<\/strong>\u3002\u540e\u7eed\u4e2d\u95f4\u4f53\u4e0e<strong>2a<\/strong>\u8fdb\u884c\u914d\u4f53\u4ea4\u6362\u5f97\u5230\u78f7\u9170\u94af\u4e2d\u95f4\u4f53<strong>D<\/strong>\u3002\u6b64\u5916\uff0c\u53e6\u4e00\u79cd\u53ef\u80fd\u9014\u5f84\uff0c\u4e2d\u95f4\u4ea7\u7269<strong>E<\/strong>\u53ef\u80fd\u7531<strong>2a<\/strong>\u7684P-H\u952e\u76f4\u63a5\u6c27\u5316\u52a0\u6210\uff0c\u7136\u540e\u751f\u6210\u76f8\u540c\u7684\u4e2d\u95f4\u4f53<strong>D<\/strong>\u3002\u6700\u540e\uff0c\u8fd8\u539f\u6d88\u9664\u5f97\u5230\u6240\u9700\u7684\u70ef\u57fa\u81a6\u9178\u916f\u4ea7\u7269\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/6-23.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-34855 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/6-23.jpg\" alt=\"\" width=\"1951\" height=\"1914\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/6-23.jpg 1951w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/6-23-300x294.jpg 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/6-23-680x667.jpg 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/6-23-768x753.jpg 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2020\/08\/6-23-1536x1507.jpg 1536w\" sizes=\"(max-width: 1951px) 100vw, 1951px\" \/><\/a><\/p>\n<p style=\"text-align: center;\">\u56fe5 \u53ef\u80fd\u7684\u50ac\u5316\u5faa\u73af<\/p>\n<h4><strong>\u8bba\u6587\u603b\u7ed3\u8bc4\u4ef7<\/strong><\/h4>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u4f5c\u8005\u53d1\u5c55\u4e86\u7b2c\u4e00\u4f8b\u94af\u50ac\u5316\u7094\u70c3\u7684\u4e0d\u5bf9\u79f0\u6c22\u81a6\u5316\u53cd\u5e94\uff0c\u9ad8\u6548\u7684\u5408\u6210\u5177\u6709P-\u624b\u6027\u70ef\u57fa\u81a6\u9178\u916f\u884d\u751f\u7269\u3002\u8be5\u53cd\u5e94\u8868\u660e\u6c22\u81a6\u5316\u662f\u5236\u5907P-\u7acb\u4f53\u6709\u673a\u78f7\u5316\u5408\u7269\u7684\u6709\u6548\u7b56\u7565\uff0c\u540c\u65f6\u8be5\u53cd\u5e94\u5177\u6709\u6761\u4ef6\u6e29\u548c\u3001\u5e95\u7269\u9002\u5e94\u8303\u56f4\u8f83\u5e7f\u7b49\u4f18\u70b9\u3002\u6b64\u5916\uff0c\u901a\u8fc7\u514b\u7ea7\u5b9e\u9a8c\u4ee5\u53ca\u540e\u671f\u7684\u884d\u751f\u5316\u53cd\u5e94\uff0c\u8fdb\u4e00\u6b65\u8bc1\u660e\u4e86\u53cd\u5e94\u7684\u5b9e\u7528\u6027\u3002<\/p>\n<h4><strong>\u53c2\u8003\u6587\u732e<\/strong><\/h4>\n<ul>\n<li>[1] Y.-S. Jang, L. Wozniak,J. Pedroni, N. Cramer, <em>Angew. Chem. Int. Ed. <\/em><strong>2018<\/strong>, <em>57<\/em>, 12901-12905. DOI:<a href=\"https:\/\/doi.org\/10.1021\/cr100304n\">10.1002\/anie.201807749<\/a><\/li>\n<li>[2] Q. Dai, W. Li, Z. Li, J. Zhang, <em>J. Am. Chem. Soc.<\/em> 2019, <em>141<\/em>, 20556-20564.DOI: <a href=\"https:\/\/doi.org\/10.1021\/jacs.9b11938\">10.1021\/jacs.9b11938<\/a><\/li>\n<li>[3] J. S. Harvey, S. J. Malcolmson, K. S. Dunne, S. J. Meek, A. L.Thompson, R. R. Schrock, A. H. Hoveyda, V. Gouverneur, <em>Angew. Chem. Int. Ed. <\/em>2009, <em>48<\/em>, 762-766.DOI:<a href=\"https:\/\/doi.org\/10.1021\/ja806572b\">1002\/anie.200805066<\/a><\/li>\n<li>[4] B. M. Trost, S. M. Spohr, A. B. Rolka, C. A. Kalnmals, <em>J. Am. Chem. Soc.<\/em> 2019, <em>141<\/em>, 14098-14103.DOI: <a href=\"https:\/\/doi.org\/10.1021\/jacs.9b07340\">10.1021\/jacs.9b07340<\/a><\/li>\n<\/ul>\n<p>\u672c\u6587\u7248\u6743\u5c5e\u4e8e<strong>\u00a0<a href=\"\/\/www.gsbet888.com\/\">Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c<\/strong>\u00a0\u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"\u5bfc\u8bfb 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Wang\u7b49\u53d1\u5c55\u4e86\u7b2c\u4e00\u4f8bPd\u50ac\u5316\u7094\u70c3\u7684\u5bf9\u6620\u9009\u62e9\u6027\u6c22\u81a6\u5316\u53cd\u5e94\uff0c\u9ad8\u6548\u7684\u5236\u5907\u5177\u6709P-\u624b\u6027\u7684\u624b\u6027\u70ef\u57fa\u81a6\u9178\u916f\u3002\u76f8\u5173\u6210\u679c\u53d1\u8868\u4e8e\uff1a \u201cPalladium-Catalyzed Asymmetric Hydrophosphorylation ofAlkynes: Facile Access to P\u2011StereogenicPhosphinates\u201d Zhiping Yang, XiaodongGu, Li-Biao Han and Jun (Joelle) Chem. Sci., 2020, 11, 7451-7455. DOI: 10.1039\/D0SC01049A \u56fe1\u4e0d\u5bf9\u79f0\u5408\u6210P-\u7acb\u4f53\u78f7\u9178\u916f \u8bba\u6587\u6982\u8981 \u4f5c\u8005\u9996\u5148\u8fdb\u884c\u6761\u4ef6\u7684\u7b5b\u9009\u7814\u7a76\u3002\u82ef\u4e59\u70941a\u548c\u4e59\u57fa\u82ef\u57fa\u81a6\u9178\u916f2a\u4f5c\u4e3a\u6a21\u578b\u5e95\u7269\uff0c\u5bf9\u5404\u79cd\u5404\u6837\u7684\u914d\u4f53\u8fdb\u884c\u521d\u6b65\u8bc4\u4f30\uff0c\u5927\u591a\u6570\u5177\u6709P-\u624b\u6027\u7684\u53cc\u81a6\u914d\u4f53\u53cd\u5e94\u6548\u679c\u8f83\u597d\u3002\u5f53L1\u4f5c\u4e3a\u914d\u4f53\u65f6\uff0c\u53cd\u5e94\u4ee570%\u7684\u6536\u7387\u548c70% ee\u987a\u5229\u5f97\u5230\u70ef\u57fa\u81a6\u9178\u916f3aa\uff08\u88681\uff0centry 1\uff09\u3002(R, R)-Ph-BPE\u914d\u4f53\u53cd\u5e94\u6027\u548c\u5bf9\u6620\u9009\u62e9\u6027\u5dee\uff08\u88681\uff0centry 2\uff09\u3002(S, S, S, S)-BIBOP\u914d\u4f53L3\u663e\u793a\u53cd\u5e94\u6d3b\u6027\u8f83\u597d\uff0c\u4f46\u4ea7\u7269\u6ca1\u6709\u5bf9\u6620\u9009\u62e9\u6027\uff08\u88681\uff0centry 3\uff09\u3002(R, R)-QuinoxP*L4\u80fd\u4ee570%\u7684\u6536\u7387\u4ee5\u53ca83%ee\u5f97\u5230\u76ee\u6807\u4ea7\u7269\uff08\u88681\uff0centry 4\uff09\u3002\u7c7b\u4f3c\u7684\u914d\u4f53(R, R)-benzP*L5\u867d\u7136\u80fd\u5f97\u523086%\u7684ee\uff0c\u4f46\u6536\u7387\u8f83\u5dee\uff08\u88681\uff0centry 5\uff09\u3002\u5f53\u4f7f\u7528Pd(dba)2\u4f5c\u4e3a\u50ac\u5316\u5242\u65f6\uff0c\u9700\u8981\u66f4\u9ad8\u7684\u53cd\u5e94\u6e29\u5ea6\u624d\u80fd\u8fdb\u884c\u53cd\u5e94\u5b8c\u6210\uff08\u88681\uff0centry 6\uff09\u3002\u4f5c\u8005\u5bf9\u6eb6\u5242\u4e5f\u8fdb\u884c\u4e86\u7b80\u8981\u8003\u5bdf\uff0cTHF\u30011,4-\u4e8c\u6c27\u516d\u73af\u548cDCE\u7684\u6536\u7387\u548c\u5bf9\u6620\u9009\u62e9\u6027\u5747\u8f83\u5dee\uff08\u88681\uff0centry 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Jang, L. Wozniak,J. Pedroni, N. Cramer, Angew. Chem. Int. Ed. 2018, 57, 12901-12905. DOI:10.1002\/anie.201807749 [2] Q. Dai, W. Li, Z. Li, J. Zhang, J. Am. Chem. Soc. 2019, 141, 20556-20564.DOI: 10.1021\/jacs.9b11938 [3] J. S. Harvey, S. 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