{"id":36683,"date":"2021-01-15T08:00:55","date_gmt":"2021-01-15T00:00:55","guid":{"rendered":"\/\/www.gsbet888.com\/?p=36683"},"modified":"2021-01-12T17:42:00","modified_gmt":"2021-01-12T09:42:00","slug":"%e5%8d%97%e5%bc%80%e5%a4%a7%e5%ad%a6%e6%b1%aa%e6%b8%85%e6%b0%91%e6%95%99%e6%8e%88%e8%af%be%e9%a2%98%e7%bb%84green-chem-%ef%bc%9a-%e7%94%b5%e6%b0%a7%e5%8c%96%e5%ae%9e%e7%8e%b0%e5%96%b9%e5%96%94","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/recentpaper\/2021\/01\/%e5%8d%97%e5%bc%80%e5%a4%a7%e5%ad%a6%e6%b1%aa%e6%b8%85%e6%b0%91%e6%95%99%e6%8e%88%e8%af%be%e9%a2%98%e7%bb%84green-chem-%ef%bc%9a-%e7%94%b5%e6%b0%a7%e5%8c%96%e5%ae%9e%e7%8e%b0%e5%96%b9%e5%96%94.html","title":{"rendered":"\u5357\u5f00\u5927\u5b66\u6c6a\u6e05\u6c11\u6559\u6388\u8bfe\u9898\u7ec4Green Chem.\uff1a \u7535\u6c27\u5316\u5b9e\u73b0\u55b9\u5594\u5549\u916e\u4e0e\u6709\u673a\u787c\u5316\u5408\u7269\u7684C-H\u70f7\u57fa\u5316"},"content":{"rendered":"
\u672c\u6587\u4f5c\u8005\uff1a\u6749\u6749<\/strong><\/p>\n \u867d\u7136C-B\u952e\u7684\u81ea\u7531\u57fa\u88c2\u89e3\u5df2\u662f\u4e00\u79cd\u5b9e\u73b0C-H\u529f\u80fd\u5316\u7684\u6709\u6548\u7b56\u7565\uff0c\u4f46\u5b9e\u9645\u4e0a\u4ecd\u5177\u6709\u4e00\u5b9a\u7684\u6311\u6218\u3002\u8fd1\u65e5\uff0c\u5357\u5f00\u5927\u5b66\u6c6a\u6e05\u6c11\u6559\u6388\u8bfe\u9898\u7ec4\u5728Green Chem.<\/em>\u53d1\u8868\u8bba\u6587\uff0c\u62a5\u9053\u4e86\u4e00\u79cd\u6e29\u548c\u7684\u7535\u6c27\u5316\u65b9\u6cd5\uff0c\u53ef\u901a\u8fc7\u70f7\u57fa\u787c\u9178\uff08\u916f\uff09\u548c\u4e09\u6c1f\u787c\u9178\u70f7\u57fa\u916f\u7684\u81ea\u7531\u57fa\u52a0\u6210\u53cd\u5e94\uff0c\u5b9e\u73b0\u55b9\u5594\u5549-2(1H<\/em>)-\u916e\u7684C-H\u70f7\u57fa\u5316\u53cd\u5e94\uff0c\u83b7\u5f97C-C\u5076\u8054\u4ea7\u7269\u3002<\/p>\n Electro-oxidative C-H Alkylation of Quinoxalin-2(1H)-ones with Organoboron Compounds \u78b3\u81ea\u7531\u57fa\uff0c\u662f\u6784\u5efaC-C\u952e\u53cd\u5e94\u4e2d\u5e38\u7528\u7684\u4e2d\u95f4\u4f53\u3002\u5728\u6e29\u548c\u6761\u4ef6\u4e0b\u901a\u8fc7\u6709\u673a\u787c\u5316\u5408\u7269\u7684\u53bb\u787c\u5316\u8fc7\u7a0b\uff0c\u53ef\u751f\u6210\u70f7\u57fa\u81ea\u7531\u57fa\u3002\u4f46\u7531\u4e8eC-B\u952e\u5177\u6709\u9ad8\u6c27\u5316\u7535\u4f4d\uff08Scheme 1a\uff09\uff0c\u5b83\u4eec\u7684\u88c2\u89e3\u9700\u8981\u82db\u523b\u7684\u6761\u4ef6\u3002\u5728\u7ecf\u5178\u65b9\u6cd5\u4e2d\uff08Scheme 1b\uff09\uff0c\u4e09\u6c1f\u787c\u9178\u70f7\u57fa\u916f\u548c\u787c\u9178\u9700\u5316\u5b66\u8ba1\u91cf\u7684\u5f3a\u6c27\u5316\u5242\uff08\u5982AgNO3<\/sub>\/K2<\/sub>S2<\/sub>O8<\/sub>\uff0cMn(OAc)3<\/sub>\u548cCu(OAc)2<\/sub>\u6216O2<\/sub>\uff09\u8fdb\u884c\u5355\u7535\u5b50\u6c27\u5316\u3002\u4e09\u6c1f\u787c\u9178\u70f7\u57fa\u916f\u4e5f\u53ef\u5728\u50ac\u5316\u5149\u6c27\u5316\u8fd8\u539f\u6761\u4ef6\u4e0b\u8fdb\u884c\u5355\u7535\u5b50\u8f6c\u79fb\u751f\u6210\u70f7\u57fa\u81ea\u7531\u57fa[1]<\/sup>\uff0c\u540c\u65f6\uff0c\u5728\u8def\u6613\u65af\u78b1\u50ac\u5316\u4e0b\u70f7\u57fa\u787c\u9178\u548c\u916f\u53ef\u901a\u8fc7\u5149\u6c27\u5316\u8fd8\u539f\u6d3b\u5316\u800c\u8f6c\u5316\u4e3a\u70f7\u57fa\u81ea\u7531\u57fa[2]<\/sup>\u3002\u7535\u5316\u5b66\u6c27\u5316\u4f5c\u4e3a\u4e00\u79cd\u7eff\u8272\u73af\u4fdd\u7684\u7b56\u7565\uff0c\u53ef\u66ff\u4ee3\u4f20\u7edf\u7684\u5316\u5b66\u6c27\u5316\u5242\uff0c\u5e76\u4f7f\u7528\u7535\u5b50\u4f5c\u4e3a\u6e05\u6d01\u7684\u53ef\u518d\u751f\u8bd5\u5242\u3002\u4f46\u787c\u9178\u884d\u751f\u7269\u7684\u9ad8\u6c27\u5316\u7535\u4f4d\u53ef\u80fd\u5bfc\u81f4\u81ea\u7531\u57fa\u4e8c\u805a\u5316\u6216\u8fc7\u6c27\u5316\u4ee5\u751f\u6210\u78b3\u6b63\u79bb\u5b50\u5bfc\u81f4\u4ece\u9633\u6781\u4ea7\u751f\u70f7\u57fa\u81ea\u7531\u57fa\u7684\u65b9\u6cd5\u4ecd\u672a\u5f00\u53d1\u51fa\u6765\uff0c\u3002\u4ec5\u6709\u5c11\u6570\u6587\u732e\u62a5\u9053\u5173\u4e8e\u6c27\u5316\u8fd8\u539f\u9014\u5f84\u7684\u4f8b\u5b50\uff0c\u5982\u5149\u6c27\u5316\u8fd8\u539f\u50ac\u5316\u5242[3]<\/sup>\u6216Mn(OAc)3<\/sub>\u50ac\u5316\u5242[4]<\/sup>\uff08Scheme 1b\uff09\u3002\u6b64\u5916\uff0c\u5173\u4e8e\u5c06\u6709\u673a\u787c\u5316\u5408\u7269\u76f4\u63a5\u7528\u4f5c\u78b3\u81ea\u7531\u57fa\u7684\u7535\u6c27\u5316C-H\u5b98\u80fd\u5316\u53cd\u5e94\u4e5f\u5c1a\u672a\u5b9e\u73b0\u3002\u5728\u6b64\uff0c\u5357\u5f00\u5927\u5b66\u6c6a\u6e05\u6c11\u6559\u6388\u8bfe\u9898\u7ec4\u62a5\u9053\u4e86\u4e00\u79cd\u6e29\u548c\u7684\u7535\u5316\u5b66\u6c27\u5316\u7b56\u7565\uff0c\u4f7f\u7528\u70f7\u57fa\u787c\u9178\u548c\u916f\u4ee5\u53ca\u4e09\u6c1f\u787c\u9178\u70f7\u57fa\u916f\u4f5c\u4e3a\u70f7\u57fa\u5316\u5242\uff0c\u5b9e\u73b0\u4e86\u55b9\u5594\u5549-2(1H<\/em>)-\u916e\u7684C-H\u70f7\u57fa\u5316\u53cd\u5e94\uff08Scheme 1c\uff09\u3002<\/p>\n \u9996\u5148\uff0c\u4f5c\u8005\u4ee51-\u7532\u57fa\u55b9\u5594\u5549-2(1H<\/em>)-\u916e1<\/strong>\u548c\u73af\u5df1\u57fa\u787c\u91782<\/strong>\u4f5c\u4e3a\u6a21\u578b\u5e95\u7269\uff0c\u8fdb\u884c\u4e86\u76f8\u5173\u53cd\u5e94\u6761\u4ef6\u7684\u7b5b\u9009\uff08Table 1\uff09\u3002\u53cd\u5e94\u7684\u6700\u4f73\u6761\u4ef6\u4e3a\uff1a\u4ee5\u77f3\u58a8\u677f\u4f5c\u4e3a\u7535\u6781\uff0cDMF\u4f5c\u4e3a\u6eb6\u5242\uff0cn<\/sup><\/em>Bu4<\/sub>NPF6<\/sub>\uff082.0\u5f53\u91cf\uff09\u4f5c\u4e3a\u7535\u89e3\u8d28\uff0c\u4e09\u6c1f\u4e59\u9178\uff08TFA\uff0c4.0\u5f53\u91cf\uff09\u4f5c\u4e3a\u6dfb\u52a0\u5242\uff0c\u7535\u6d41\u5bc6\u5ea6\u4e3a10 mA \/cm2<\/sup>\uff0c\u5373\u53ef\u83b7\u5f9785\uff05\u6536\u7387\u7684\u70f7\u57fa\u5316\u4ea7\u72693<\/strong>\u3002<\/p>\n \u5728\u83b7\u5f97\u4e0a\u8ff0\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u540e\uff0c\u4f5c\u8005\u5f00\u59cb\u5bf9\u55b9\u5594\u5549\u916e\u5e95\u72691<\/strong>\u8fdb\u884c\u4e86\u6269\u5c55\uff08Scheme 2\uff09\u3002\u53cd\u5e94\u7ed3\u679c\u8868\u660e\uff0c\u82b3\u73af\u4e0a\u5177\u6709\u5404\u79cd\u53d6\u4ee3\u57fa\uff08\u5982\u7532\u57fa\u3001\u6c2f\u3001\u6c1f\u3001\u4e09\u6c1f\u7532\u57fa\u3001\u6c30\u57fa\u3001\u7532\u6c27\u57fa\u7b49\uff09\u7684\u5e95\u7269\u5747\u4e0e2<\/strong>\u5e73\u7a33\u53cd\u5e94\uff0c\u4ee5\u4e2d\u7b49\u81f3\u826f\u597d\u7684\u6536\u7387\u83b7\u5f97\u76f8\u5e94\u7684\u4ea7\u72694<\/strong>–12<\/strong>\u3002\u540c\u65f6\uff0c\u5404\u79cd\u6c2e\u53d6\u4ee3\u7684\u5e95\u7269\uff08\u4e19\u57fa\u3001\u70ef\u57fa\u3001\u7094\u4e19\u57fa\u3001\u82c4\u57fa\u7b49\uff09\u4e5f\u53ef\u4e0e2<\/strong>\u987a\u5229\u53cd\u5e94\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u4ea7\u726913<\/strong>–19<\/strong>\u3002<\/p>\n \u968f\u540e\uff0c\u4f5c\u8005\u5bf9\u6709\u673a\u787c\u5316\u5408\u7269\u7684\u8303\u56f4\u8fdb\u884c\u4e86\u6269\u5c55\uff08Scheme 3\uff09\u3002\u53cd\u5e94\u7ed3\u679c\u8868\u660e\uff0c\u4e00\u7cfb\u5217\u65e0\u73af\u548c\u73af\u72b6\u7684\u4f2f\u3001\u4ef2\u548c\u53d4\u70f7\u57fa\u787c\u9178\u5747\u4e3a\u5408\u9002\u5e95\u7269\uff083<\/strong>\uff0c20<\/strong>–24<\/strong>\uff09\u3002\u540c\u65f6\uff0c\u73af\u72b6\u4ef2\u548c\u53d4\u6709\u673a\u4e09\u6c1f\u787c\u9178\u916f\u4e5f\u53ef\u7528\u4e8e\u53cd\u5e94\u4e2d\uff083<\/strong>\u300121<\/strong>\u300123\u300124<\/strong>\uff09\u3002\u6b64\u5916\uff0c\u73af\u72b6\u548c\u53d4\u787c\u9178\u916f\u4e5f\u4e0e\u4f53\u7cfb\u517c\u5bb9\uff083<\/strong>\u300124<\/strong>\uff09\u3002<\/p>\n \u6742\u82b3\u57fa\u9aa8\u67b6\u5e7f\u6cdb\u5b58\u5728\u4e8e\u5929\u7136\u4ea7\u7269\u3001\u5c0f\u5206\u5b50\u836f\u7269\u3001\u6709\u673a\u6750\u6599\u548c\u91d1\u5c5e\u50ac\u5316\u5242\u7684\u914d\u4f53\u4e2d\uff0c\u6b64\u7c7b\u7ed3\u6784\u7684\u6784\u5efa\u6781\u5177\u4ef7\u503c\u3002\u5728\u4e0a\u8ff0\u6807\u51c6\u6761\u4ef6\u4e0b\uff0c\u5177\u6709\u6742\u82b3\u57fa\u9aa8\u67b6\u7684\u82ef\u5e76\u55b9\u5594\u5549\u916e\uff0826<\/strong>\uff09\u548c\u83f2\u5576\uff0827<\/strong>\uff09\u5747\u4e3a\u5408\u9002\u7684\u5e95\u7269\uff0c\u4ece\u800c\u8fdb\u4e00\u6b65\u8bc1\u660e\u4e86\u8be5\u53cd\u5e94\u5728\u836f\u7269\u540e\u671f\u884d\u751f\u5316\u4e2d\u7684\u4ef7\u503c\uff08Scheme 4\uff09\u3002<\/p>\n \u968f\u540e\uff0c\u4e3a\u4e86\u8fdb\u4e00\u6b65\u8bc1\u660e\u53cd\u5e94\u7684\u5b9e\u7528\u6027\uff0c\u4f5c\u8005\u8fdb\u884c\u4e86\u514b\u7ea7\u53cd\u5e94\uff0c\u5728\u6807\u51c6\u6761\u4ef6\u4e0b\uff0c\u540c\u6837\u83b7\u5f97\u9884\u671f79\uff05\u6536\u7387\u7684\u4ea7\u72693<\/strong>\uff08Scheme 5\uff09\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8be5\u53cd\u5e94\u53ef\u4ee5\u4f7f\u7528\u7535\u6c60\u4f5c\u4e3a\u7535\u6e90\uff0c\u4ece\u800c\u907f\u514d\u590d\u6742\u7684\u76f4\u6d41\u7535\u6e90\u8bbe\u5907\u3002\u6b64\u5916\uff0c\u901a\u8fc7\u70f7\u57fa\u5316\u4ea7\u726913<\/strong>\u7684\u70b9\u51fb\u53cd\u5e94\uff0c\u53ef\u5c06\u7094\u70c3\u8f6c\u5316\u4e3a\u4e09\u5511\u9aa8\u67b6\uff0825<\/strong>\uff0c\u4ea7\u7387\u4e3a97\uff05\uff09\u3002<\/p>\n \u4e3a\u4e86\u8fdb\u4e00\u6b65\u4e86\u89e3\u53cd\u5e94\u7684\u673a\u7406\uff0c\u4f5c\u8005\u8fdb\u884c\u4e86\u76f8\u5173\u7684\u5bf9\u7167\u5b9e\u9a8c\uff08Scheme 6\uff09\u3002\u9996\u5148\uff0c\u5728\u6807\u51c6\u6761\u4ef6\u4e0b\uff0c\u52a0\u5165\u81ea\u7531\u57fa\u6291\u5236\u5242BHT\u540e\uff0c\u53cd\u5e94\u88ab\u6291\u5236\uff0c\u4ece\u800c\u8868\u660e\u53cd\u5e94\u6d89\u53ca\u81ea\u7531\u57fa\u7684\u53c2\u4e0e\u3002\u5176\u6b21\uff0c\u4f7f\u7528N<\/em>-\u82ef\u57fa\u7532\u57fa\u4e19\u70ef\u9170\u80fa\u4e0e\u787c\u91782<\/strong>\u5728\u6807\u51c6\u6761\u4ef6\u4e0b\u53cd\u5e94\u65f6\uff0c\u83b7\u5f97\u4ea7\u726929<\/strong>\uff0c\u6536\u7387\u4e3a8\uff05\uff0c\u4ece\u800c\u8868\u660e\u53cd\u5e94\u5f62\u6210\u4e86\u70f7\u57fa\u81ea\u7531\u57fa\u3002<\/p>\n\u5bfc\u8bfb<\/h4>\n
\nKaikai Niu, Yanke Hao, Lingyun Song, Yuxiu Liu and Qingmin Wang*
\nGreen Chem. ASAP DOI:10.1039\/D0GC03892J<\/a><\/p><\/blockquote>\n<\/a><\/p>\n
\u6b63\u6587<\/h4>\n
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