{"id":36804,"date":"2021-01-25T08:00:17","date_gmt":"2021-01-25T00:00:17","guid":{"rendered":"\/\/www.gsbet888.com\/?p=36804"},"modified":"2021-01-07T21:11:49","modified_gmt":"2021-01-07T13:11:49","slug":"asao-yamamoto%e8%8b%af%e7%8e%af%e5%8c%96","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/reactions\/2021\/01\/asao-yamamoto%e8%8b%af%e7%8e%af%e5%8c%96.html","title":{"rendered":"Asao-Yamamoto\u82ef\u73af\u5316"},"content":{"rendered":"

\u6982\u8981<\/strong><\/h4>\n

Asao-Yamamoto\u82ef\u73af\u5316 (Asao-Yamamoto benzannulation)\u662f\u5728\u4e09\u5364\u5316\u91d1[1]-[3]<\/sup>\u3001AuNPore (nanoporous gold)[4]<\/sup>\u3001\u4e09\u6c1f\u7532\u78fa\u9178\u94dc[2]-[3], [5]<\/sup>\u3001\u5364\u5316\u94dc[5]<\/sup>\u6216\u6c2f\u5316\u950c[6]<\/sup>\u50ac\u5316\u6761\u4ef6\u4e0b\uff0c\u901a\u8fc7\u90bb\u7094\u57fa\u82ef\u7532\u919b\u6216\u70ef\u57fa\u7094\u919b (enynal)\u4e0e\u5404\u7c7b\u7094\u57fa\u5316\u5408\u7269\u4e4b\u95f4\u7684\u5206\u5b50\u95f4[1]-[2], [4]-[11]<\/sup>\u6216\u5206\u5b50\u5185[3]<\/sup>\u7684\u5f62\u5f0f[4 + 2]\u82ef\u73af\u5316\u8fc7\u7a0b (formal [4 + 2] benzannulation)\uff0c\u83b7\u5f97\u4e00\u7cfb\u5217\u8418\u73af\u6216\u82ef\u73af\u5316\u5408\u7269\u7684\u53cd\u5e94\u3002\u8be5\u53cd\u5e94\u7531\u65e5\u672cTohoku\u5927\u5b66\u7406\u5b66\u9662\u5316\u5b66\u7cfb (\u6771\u5317\u5927\u5b66\u7406\u5b66\u90e8\u5316\u5b66\u6559\u5ba4, Department of Chemistry, Graduate School of Science, Tohoku University)\u7684Asao (\u6d45\u5c3e \u76f4\u6a39,Asao Naoki)\u4e0eYamamoto (\u5c71\u672c \u5609\u5247,Yamamoto Yoshinori)\u57282002\u5e74\u9996\u6b21\u62a5\u9053[1]<\/sup>\u3002<\/p>\n

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\"\"\"\"\"\"<\/a><\/p>\n

Asao-Yamamoto\u82ef\u73af\u5316\u53cd\u5e94\u5177\u6709\u4f18\u826f\u7684\u4ea7\u7387\u3001\u6e29\u548c\u7684\u53cd\u5e94\u6761\u4ef6\u4e0e\u4f18\u826f\u7684\u533a\u57df\u9009\u62e9\u6027\u3002\u5728\u5404\u7c7b\u8418\u73af\u6216\u82ef\u73af\u5316\u5408\u7269[1]-[4], [7]-[11]<\/sup>\u3001\u5364\u4ee3\u4e0e\u591a\u5364\u4ee3\u82b3\u70c3[5]-[6]<\/sup>\u3001\u805a\u82ef\u7c7b\u5171\u8f6d\u805a\u5408\u7269[12]<\/sup>\u7684\u6784\u5efa\u4ee5\u53ca\u751f\u7406\u6d3b\u6027\u5929\u7136\u4ea7\u7269\u7684\u5168\u5408\u6210[13]<\/sup>\u4e2d\u5177\u6709\u5e7f\u9614\u7684\u5e94\u7528\u524d\u666f\u3002<\/p>\n

\u57fa\u672c\u6587\u732e<\/strong><\/h4>\n[1] N. Asao, K. Takahashi, S. Lee, T. Kasahara, Y. Yamamoto, J. Am. Chem. Soc.\u00a02002, 124, 43, 12650. doi: 10.1021\/ja028128z<\/a>.<\/p>\n[2] N. Asao, T. Nogami, S. Lee, Y. Yamamoto, J. Am. Chem. Soc.\u00a02003, 125, 36, 10921. doi: 10.1021\/ja036927r<\/a>.<\/p>\n[3] N. Asao, K. Sato, Menggenbateer, Y. Yamamoto, J. Org.Chem. 2005, 70, 3682. doi: 10.1021\/jo0500434<\/a>.<\/p>\n[4] N. Asao, Y. Seya, Y. Yamamoto, M. Chen, W. Zhang, A. Inoue, Synthesis 2012, 66. doi: 10.1055\/s-0031-1289527.<\/a><\/p>\n[5] D. Lehnherr, J. M. Alzola, E. B. Lobkovsky, W. R. Dichtel, Chem. – Eur. J. 2015, 21, 18122. doi: 10.1002\/chem.201503418<\/a>.<\/p>\n[6] S. J. Hein, D. Lehnherr, W. R. Dichtel, Chem. Sci. 2017, 8, 5675. doi: 10.1039\/C7SC01625E<\/a>.<\/p>\n[7] H. Arslan, K. L. Walker, W. R. Dichtel, Org. Lett. 2014, 16, 5926. doi: 10.1021\/ol502938y<\/a>.<\/p>\n[8] D. M. Jones, G. B. Dudley, Tetrahedron 2010,\u00a066, 4860. doi: 10.1016\/j.tet.2010.03.014<\/a>.<\/p>\n[9] S. J. Hein, H. Arslan, I. Keresztes, W. R. Dichtel, Org. Lett. 2014, 16, 4416. doi: 10.1021\/ol501874s<\/a>.<\/p>\n[10] D. Lehnherr, J. M. Alzola, C. R. Mulzer, S. J. Hein, W. R. Dichtel, J. Org. Chem. 2017, 82, 2004. doi: 10.1021\/acs.joc.6b02840<\/a>.<\/p>\n[11] S. J. Hein, D. Lehnherr, H. Arslan, F. J. Uribe-Romo, W. R. Dichtel, Acc. Chem. Res.\u00a02017, 50, 11, 2776. doi: 10.1021\/acs.accounts.7b00385<\/a>.<\/p>\n[12] H. Arslan, J. D. Saathoff, D. N. Bunck, P. Clancy, W. R. Dichtel, Angew. Chem. Int. Ed. 2012, 51, 12051. doi: 10.1002\/anie.201206964<\/a>.<\/p>\n[13] K. Sato, N. Asao, Y. Yamamoto, J. Org. Chem.\u00a02005, 70, 22, 8977. doi: 10.1021\/jo051444m<\/a>.<\/p>\n

\u53cd\u5e94\u673a\u7406<\/strong><\/h4>\n

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\u53c2\u8003\u6587\u732e<\/strong><\/h4>\n[1] H. Arslan, K. L. Walker, W. R. Dichtel, Org. Lett. 2014, 16, 5926. doi: 10.1021\/ol502938y<\/a>.<\/p>\n[2] S. J. Hein, D. Lehnherr, H. Arslan, F. J. Uribe-Romo, W. R. Dichtel, Acc. Chem. Res.\u00a02017, 50, 11, 2776. doi: 10.1021\/acs.accounts.7b00385<\/a>.<\/p>\n[3] N. Asao, T. Shimada, T. Shimada, Y. Yamamoto, J. Am. Chem. Soc. 2001, 123, 10899. doi: 10.1021\/ja011316p<\/a>.<\/p>\n[4] N. Asao, Y. Yamamoto, Bull. Chem. Soc. Jpn. 2000, 73, 1071. doi: 10.1246\/bcsj.73.1071<\/a>.<\/p>\n

\u53cd\u5e94\u5b9e\u4f8b<\/strong><\/h4>\n

\u8418\u73af\u5316\u5408\u7269\u7684\u5408\u6210[1]<\/sup><\/p>\n

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\u82ef\u73af\u5316\u5408\u7269\u7684\u5408\u6210[2]<\/sup><\/p>\n

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(+)-ochromycinone\u4e0e(+)-rubiginoneB2<\/sub>\u7684\u5168\u5408\u6210[3]<\/sup><\/p>\n

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\u82ef\u5e76\u831a\u7684\u5408\u6210[4]<\/sup><\/p>\n

\"\"<\/a><\/p>\n

2,3-\u4e8c\u82b3\u57fa\u8418\u7684\u5408\u6210[5]<\/sup><\/p>\n

\"\"<\/a><\/p>\n

polyphenylene\u7684\u5408\u6210[6]<\/sup><\/p>\n

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\u5b9e\u9a8c\u6b65\u9aa4<\/strong><\/h4>\n

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\u53c2\u8003\u6587\u732e<\/strong><\/h4>\n[1] N. Asao, K. Takahashi, S. Lee, T. Kasahara, Y. Yamamoto, J. Am. Chem. Soc.\u00a02002, 124, 43, 12650. doi: 10.1021\/ja028128z<\/a>.<\/p>\n[2] N. Asao, T. Nogami, S. Lee, Y. Yamamoto, J. Am. Chem. Soc.\u00a02003, 125, 36, 10921. doi: 10.1021\/ja036927r<\/a>.<\/p>\n[3] K. Sato, N. Asao, Y. Yamamoto, J. Org. Chem.\u00a02005, 70, 22, 8977. doi: 10.1021\/jo051444m<\/a>.<\/p>\n[4] D. M. Jones, G. B. Dudley, Tetrahedron 2010,\u00a066, 4860. doi: 10.1016\/j.tet.2010.03.014<\/a>.<\/p>\n[5] H. Arslan, K. L. Walker, W. R. Dichtel, Org. Lett. 2014, 16, 5926. doi: 10.1021\/ol502938y<\/a>.<\/p>\n[6] H. Arslan, J. D. Saathoff, D. N. Bunck, P. Clancy, W. R. Dichtel, Angew. Chem. Int. Ed. 2012, 51, 12051. doi: 10.1002\/anie.201206964<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"\u6982\u8981 Asao-Yamamoto\u82ef\u73af\u5316 (Asao-Yamamoto benzannulation)\u662f\u5728\u4e09\u5364\u5316\u91d1[1]-[3]\u3001AuNPore (nanoporous gold)[4]\u3001\u4e09\u6c1f\u7532\u78fa\u9178\u94dc[2]-[3], [5]\u3001\u5364\u5316\u94dc[5]\u6216\u6c2f\u5316\u950c[6]\u50ac\u5316\u6761\u4ef6\u4e0b\uff0c\u901a\u8fc7\u90bb\u7094\u57fa\u82ef\u7532\u919b\u6216\u70ef\u57fa\u7094\u919b (enynal)\u4e0e\u5404\u7c7b\u7094\u57fa\u5316\u5408\u7269\u4e4b\u95f4\u7684\u5206\u5b50\u95f4[1]-[2], [4]-[11]\u6216\u5206\u5b50\u5185[3]\u7684\u5f62\u5f0f[4 + 2]\u82ef\u73af\u5316\u8fc7\u7a0b (formal [4 + 2] benzannulation)\uff0c\u83b7\u5f97\u4e00\u7cfb\u5217\u8418\u73af\u6216\u82ef\u73af\u5316\u5408\u7269\u7684\u53cd\u5e94\u3002\u8be5\u53cd\u5e94\u7531\u65e5\u672cTohoku\u5927\u5b66\u7406\u5b66\u9662\u5316\u5b66\u7cfb (\u6771\u5317\u5927\u5b66\u7406\u5b66\u90e8\u5316\u5b66\u6559\u5ba4, Department of Chemistry, Graduate School of Science, Tohoku University)\u7684Asao (\u6d45\u5c3e \u76f4\u6a39,Asao Naoki)\u4e0eYamamoto (\u5c71\u672c \u5609\u5247,Yamamoto Yoshinori)\u57282002\u5e74\u9996\u6b21\u62a5\u9053[1]\u3002 Asao-Yamamoto\u82ef\u73af\u5316\u53cd\u5e94\u5177\u6709\u4f18\u826f\u7684\u4ea7\u7387\u3001\u6e29\u548c\u7684\u53cd\u5e94\u6761\u4ef6\u4e0e\u4f18\u826f\u7684\u533a\u57df\u9009\u62e9\u6027\u3002\u5728\u5404\u7c7b\u8418\u73af\u6216\u82ef\u73af\u5316\u5408\u7269[1]-[4], [7]-[11]\u3001\u5364\u4ee3\u4e0e\u591a\u5364\u4ee3\u82b3\u70c3[5]-[6]\u3001\u805a\u82ef\u7c7b\u5171\u8f6d\u805a\u5408\u7269[12]\u7684\u6784\u5efa\u4ee5\u53ca\u751f\u7406\u6d3b\u6027\u5929\u7136\u4ea7\u7269\u7684\u5168\u5408\u6210[13]\u4e2d\u5177\u6709\u5e7f\u9614\u7684\u5e94\u7528\u524d\u666f\u3002 \u57fa\u672c\u6587\u732e [1] N. Asao, K. Takahashi, S. Lee, T. Kasahara, Y. Yamamoto, J. Am. Chem. Soc.\u00a02002, 124, 43, 12650. doi: 10.1021\/ja028128z. [2] N. Asao, T. Nogami, S. Lee, Y. Yamamoto, J. Am. Chem. Soc.\u00a02003, 125, 36, 10921. doi: 10.1021\/ja036927r. [3] N. Asao, K. Sato, Menggenbateer, Y. Yamamoto, J. Org.Chem. 2005, 70, 3682. doi: 10.1021\/jo0500434. [4] N. Asao, Y. Seya, Y. Yamamoto, M. Chen, W. Zhang, A. Inoue, Synthesis 2012, 66. doi: 10.1055\/s-0031-1289527. [5] D. Lehnherr, J. […]","protected":false},"author":21,"featured_media":36785,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2],"tags":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2021\/01\/2-3.png","jetpack_shortlink":"https:\/\/wp.me\/p96op1-9zC","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/36804"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/21"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=36804"}],"version-history":[{"count":1,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/36804\/revisions"}],"predecessor-version":[{"id":36805,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/36804\/revisions\/36805"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/36785"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=36804"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=36804"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=36804"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}