{"id":40142,"date":"2021-09-24T08:00:28","date_gmt":"2021-09-24T00:00:28","guid":{"rendered":"\/\/www.gsbet888.com\/?p=40142"},"modified":"2021-10-06T12:26:27","modified_gmt":"2021-10-06T04:26:27","slug":"%e7%be%8e%e5%9b%bdcornell%e5%a4%a7%e5%ad%a6t-h-lambert%e6%95%99%e6%8e%88%e8%af%be%e9%a2%98%e7%bb%84jacs%ef%bc%9a-%e9%80%9a%e8%bf%87%e7%94%b5%e5%8c%96%e5%ad%a6%e5%85%89%e5%82%ac%e5%8c%96%e7%9a%84ritt","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/recentpaper\/2021\/09\/%e7%be%8e%e5%9b%bdcornell%e5%a4%a7%e5%ad%a6t-h-lambert%e6%95%99%e6%8e%88%e8%af%be%e9%a2%98%e7%bb%84jacs%ef%bc%9a-%e9%80%9a%e8%bf%87%e7%94%b5%e5%8c%96%e5%ad%a6%e5%85%89%e5%82%ac%e5%8c%96%e7%9a%84ritt.html","title":{"rendered":"\u7f8e\u56fdCornell\u5927\u5b66T. H. Lambert\u6559\u6388\u8bfe\u9898\u7ec4JACS\uff1a \u901a\u8fc7\u7535\u5316\u5b66\u5149\u50ac\u5316\u7684Ritter\u53cd\u5e94\u65b9\u6cd5\u5b66\u8fdb\u884c\u7684C-H\u952e\u80fa\u5316"},"content":{"rendered":"

\u672c\u6587\u4f5c\u8005\uff1a\u6749\u6749<\/strong><\/p>\n

\u5bfc\u8bfb<\/h4>\n

\u8fd1\u671f\uff0c\u7f8e\u56fdCornell\u5927\u5b66T.\u00a0H. Lambert\u6559\u6388\u8bfe\u9898\u7ec4\u5728JACS<\/em>\u4e2d\u53d1\u8868\u8bba\u6587\uff0c\u62a5\u9053\u4e00\u79cd\u901a\u8fc7\u7535\u5316\u5b66\u5149\u50ac\u5316\u7684Ritter\u578b\u53cd\u5e94\u65b9\u6cd5\u5b66\u8fdb\u884c\u7684C-H\u952e\u80fa\u5316\u7814\u7a76\u3002\u8fd9\u4e00\u5168\u65b0\u7684C-H\u952e\u80fa\u5316\u7b56\u7565\u4e2d\u91c7\u7528TAC\u79bb\u5b50\u00a0(trisaminocyclopropenium ion) \u4f5c\u4e3a\u50ac\u5316\u5242\uff0c\u5728\u5149\u8f90\u5c04\u4ee5\u53ca\u7535\u5316\u5b66\u53cd\u5e94\u6761\u4ef6\u4e0b\uff0c\u80fd\u591f\u6210\u529f\u5730\u5728\u76f8\u5e94\u7684\u82c4\u4f4dC-H\u952e\u4e2d\u5f15\u5165\u4e59\u9170\u6c28\u57fa\u5b98\u80fd\u56e2\u3002\u540c\u65f6\uff0c\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u65e0\u9700\u9009\u62e9\u5316\u5b66\u8ba1\u91cf\u7684\u5404\u7c7b\u5316\u5b66\u6c27\u5316\u5242\u3002\u5e76\u4e14\uff0c\u8fd9\u4e00\u5168\u65b0\u7684C-H\u952e\u80fa\u5316\u7b56\u7565\u5177\u6709\u826f\u597d\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u3001\u5e7f\u6cdb\u7684\u5e95\u7269\u5e94\u7528\u8303\u56f4\u7b49\u4f18\u52bf\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u901a\u8fc7\u5bf9\u4e8e\u5404\u7c7b\u590d\u6742\u5206\u5b50\u540e\u671f\u884d\u751f\u5316\u8fc7\u7a0b\u7684\u7814\u7a76\uff0c\u8fdb\u4e00\u6b65\u9610\u660e\u8fd9\u4e00\u7b56\u7565\u7684\u5408\u6210\u5b9e\u7528\u6027\u3002<\/p>\n

C-H Amination via Electrophotocatalytic Ritter-type Reaction
\nT. Shen, T. H. Lambert, J. Am. Chem. Soc. 2021, 143, 8597. doi:10.1021\/jacs.1c03718<\/u><\/a>.<\/u><\/p><\/blockquote>\n

\"\"<\/a><\/p>\n

\u6b63\u6587<\/h4>\n

\u5c06\u672a\u6d3b\u5316\u7684C-H\u952e\u8f6c\u5316\u4e3aC-N\u952e\u7684\u53cd\u5e94\u7b56\u7565\u4f5c\u4e3a\u6709\u673a\u5408\u6210\u9886\u57df\u7684\u7814\u7a76\u70ed\u70b9\uff0c\u4e00\u76f4\u4ee5\u6765\u5907\u53d7\u5e7f\u6cdb\u5173\u6ce8\u3002\u5176\u4e2d\uff0cHoffmann-L\u00f6fler-Freitag\u53cd\u5e94\u65b9\u6cd5\u5b66\u5df2\u7ecf\u6210\u4e3a\u6784\u5efa\u590d\u6742\u5206\u5b50\u7684\u5173\u952e\u53cd\u5e94\u4e4b\u4e00\u3002\u5e76\u4e14\uff0c\u8fd1\u5e74\u6765\uff0c\u901a\u5e38\u91c7\u7528\u5149\u6c27\u5316\u8fd8\u539f\u50ac\u5316\u7684\u7b56\u7565\uff0c\u8fdb\u884cHoffmann-L\u00f6fler-Freitag\u53cd\u5e94\u7684\u76f8\u5173\u7814\u7a76[1<\/sup>]<\/sup>–<\/sup>[3<\/sup>]<\/sup>\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u901a\u8fc7\u6c2e\u70ef\u4e2d\u95f4\u4f53\u53c2\u4e0e\u7684\u4e00\u7cfb\u5217\u5408\u6210\u8f6c\u5316\u8fc7\u7a0b\uff0c\u540c\u6837\u80fd\u591f\u6709\u6548\u5730\u5b8c\u6210\u76f8\u5e94C-N\u952e\u7684\u6784\u5efa\u3002\u6b64\u5916\uff0c\u91c7\u7528\u8fc7\u6e21\u91d1\u5c5e\u914d\u5408\u7269\u53c2\u4e0e\u7684C-N\u5076\u8054\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u540c\u6837\u5907\u53d7\u5173\u6ce8\u3002\u540c\u65f6\uff0c\u5408\u6210\u5316\u5b66\u5bb6\u8fdb\u4e00\u6b65\u8bbe\u8ba1\u51fa\u4e00\u79cd\u65b0\u578b\u7684\u53cd\u5e94\u7b56\u7565\uff0c\u5c06C-H\u952e\u6c27\u5316\uff0c\u4ea7\u751f\u76f8\u5e94\u7684\u78b3\u6b63\u79bb\u5b50\uff0c\u5e76\u901a\u8fc7\u8148\u5206\u5b50\u7684\u6355\u83b7\uff0c\u6700\u7ec8\u83b7\u5f97\u4e00\u7cfb\u5217\u9170\u80fa\u4ea7\u7269 (Figure 1a)\u3002\u8fd9\u4e00\u7b56\u7565\u7684\u672c\u8d28\u4e3aRitter\u53cd\u5e94\u3002\u7136\u800c\uff0c\u4e0d\u540c\u4e4b\u5904\u5219\u5728\u4e8e\u78b3\u6b63\u79bb\u5b50\u7684\u5f62\u6210\u65b9\u5f0f\u3002\u76ee\u524d\uff0c\u50ac\u5316Ritter\u578bC-H\u80fa\u5316\u7b56\u7565\u5df2\u7ecf\u53d6\u5f97\u8bf8\u591a\u7684\u7814\u7a76\u8fdb\u5c55[<\/sup>4]<\/sup>–<\/sup>[7<\/sup>]<\/sup>\u00a0<\/sup>(Figure 1b)\u3002\u7136\u800c\uff0c\u5374\u5b58\u5728\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u9009\u62e9\u7684\u6c27\u5316\u5242\u4e0e\u5e95\u7269\u4e2d\u7684\u8bf8\u591a\u5b98\u80fd\u56e2\u65e0\u6cd5\u517c\u5bb9\u7684\u95ee\u9898\u3002\u7531\u6b64\uff0c\u4f5c\u8005\u8bbe\u60f3\uff0c\u8bbe\u8ba1\u4e00\u79cd\u65e0\u9700\u9009\u62e9\u5316\u5b66\u6c27\u5316\u5242\u7684\u7535\u5316\u5b66\u53cd\u5e94\u7b56\u7565\uff0c\u5219\u80fd\u591f\u6709\u6548\u5730\u89e3\u51b3\u4e0a\u8ff0\u7b56\u7565\u4e2d\u5b58\u5728\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u95ee\u9898\u3002\u5e76\u4e14\uff0c\u901a\u8fc7\u7535\u5316\u5b66\u65b9\u5f0f\u5b9e\u73b0\u7684Ritter\u578bC-H\u80fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u540c\u6837\u6709\u8bf8\u591a\u7684\u6587\u732e\u62a5\u9053[<\/sup>8]<\/sup>–<\/sup>[11<\/sup>]<\/sup>\u3002\u7136\u800c\uff0c\u5728\u4e0a\u8ff0\u7684\u7535\u5316\u5b66\u53cd\u5e94\u65b9\u6848\u4e2d\uff0c\u901a\u5e38\u9700\u8981\u8f83\u9ad8\u7684\u9633\u6781\u7535\u52bf\uff0c\u56e0\u800c\uff0c\u65e0\u6cd5\u83b7\u5f97\u8f83\u9ad8\u7684\u53cd\u5e94\u6536\u7387\u3002\u5e76\u4e14\uff0c\u4e0e\u5e95\u7269\u4e2d\u5b58\u5728\u7684\u591a\u79cd\u5b98\u80fd\u56e2\u540c\u6837\u65e0\u6cd5\u6709\u6548\u5730\u8fdb\u884c\u517c\u5bb9\u3002\u4e3a\u8fdb\u4e00\u6b65\u89e3\u51b3\u4e0a\u8ff0\u7535\u5316\u5b66\u7b56\u7565\u4e2d\u5b58\u5728\u7684\u76f8\u5173\u95ee\u9898\uff0c\u8fd1\u671f\uff0c\u672c\u8bfe\u9898\u5df2\u7ecf\u6210\u529f\u8bbe\u8ba1\u51fa\u4e00\u79cd\u901a\u8fc7\u7535\u5316\u5b66\u5149\u50ac\u5316\u6761\u4ef6\u4fc3\u8fdb\u7684C-H\u53cc\u80fa\u5316\u00a0(C-H diamination)\u53cd\u5e94\u65b9\u6cd5\u5b66 (Figure 1c)[12<\/sup>]<\/sup>\u3002\u53d7\u4e0a\u8ff0\u7814\u7a76\u7684\u542f\u53d1\uff0c\u8fd9\u91cc\uff0c\u672c\u6587\u5c06\u62a5\u9053\u4e00\u79cd\u7535\u5316\u5b66\u5149\u50ac\u5316\u7684Ritter\u578b\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u5728\u82c4\u57fa\u4f4d\u7f6e\u5f15\u5165\u76f8\u5e94\u7684\u4e59\u9170\u6c28\u57fa\u5b98\u80fd\u56e2\u3002\u540c\u65f6\uff0c\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u65e0\u9700\u91c7\u7528\u5316\u5b66\u8ba1\u91cf\u7684\u5404\u7c7b\u5316\u5b66\u6c27\u5316\u5242 (Figure 1c)\u3002<\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

\"\"<\/a><\/p>\n

\u9996\u5148\uff0c\u4f5c\u8005\u91c7\u75282<\/strong>\u4f5c\u4e3a\u6a21\u578b\u5e95\u7269\uff0c\u8fdb\u884c\u76f8\u5173\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316\u7b5b\u9009 (Table 1)\u3002\u8fdb\u800c\u786e\u5b9a\u6700\u4f73\u7684\u53cd\u5e94\u6761\u4ef6\u4e3a\uff1a\u91c7\u75288 mol%\u00a0TAC 1<\/strong>\u4f5c\u4e3a\u50ac\u5316\u5242\uff0cn<\/em>-Bu4<\/sub>NPF6<\/sub>\u4f5c\u4e3a\u7535\u89e3\u8d28\uff0c\u9009\u62e9\u78b3\u6be1\u9633\u6781 (carbon felt anode)\u4e0e\u94c2\u9634\u6781\uff0c\u4e59\u8148\u4f5c\u4e3a\u53cd\u5e94\u6eb6\u5242\uff0c\u540c\u65f6\u52a0\u5165TFA\u4e0e\u6c34\uff0c\u5728H\u578b\u9694\u819c\u7535\u89e3\u69fd (H-type divided cell,\u00a0Ecell<\/sub>\u00a0= 2.2 V, Eanode<\/sub>\u00a0= 1.6 V vs SCE)\u4ee5\u53ca\u901a\u8fc7CFL (compact fluorescent light)\u63d0\u4f9b\u7684\u53ef\u89c1\u5149\u8f90\u5c04\u6761\u4ef6\u4e0b\u8fdb\u884c\u53cd\u5e94\uff0c\u6700\u7ec8\u83b7\u5f97\u76f8\u5e94\u7684\u4e59\u9170\u80fa\u4ea7\u72693<\/strong>\uff0c\u6536\u7387\u4e3a77%\u3002<\/p>\n

\"\"<\/a><\/p>\n

H-type divided cell<\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

Set up the H-type divided cell with the CFL<\/p>\n

\u5728\u83b7\u5f97\u4e0a\u8ff0\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u4e4b\u540e\uff0c\u4f5c\u8005\u5f00\u59cb\u5bf9\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u7684\u5e95\u7269\u5e94\u7528\u8303\u56f4\u8fdb\u884c\u7814\u7a76 (Table 2)\u3002\u8be5\u5c0f\u7ec4\u53d1\u73b0\uff0c\u4e0a\u8ff0\u7684\u6807\u51c6\u53cd\u5e94\u6761\u4ef6\u5bf9\u4e8e\u7532\u82ef\u4e0e4-\u5364\u4ee3\u7532\u82ef\u5e95\u7269\uff0c\u5747\u80fd\u591f\u4ee5\u826f\u597d\u7684\u53cd\u5e94\u6536\u7387\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u82c4\u57fa\u4e59\u9170\u80fa\u4ea7\u72695<\/strong>–9<\/strong>\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8be5\u5c0f\u7ec4\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u5e95\u7269\u4e2d\u5364\u7d20\u53d6\u4ee3\u57fa\u56e2\u7684\u4f4d\u7f6e\uff0c\u5bf9\u4e8e\u53cd\u5e94\u6536\u7387\u5177\u6709\u8f83\u4e3a\u663e\u8457\u7684\u5f71\u54cd\uff0c\u5176\u4e2d\uff0c\u4e0e4-\u6eb4\u4ee3\u4ea7\u72698<\/strong>\u7684\u53cd\u5e94\u6536\u7387\u76f8\u6bd4\uff0c\u800c2-\u6eb4\u4ee3\u4ea7\u726910<\/strong>\u4e0e3-\u6eb4\u4ee3\u4ea7\u726911<\/strong>\u7684\u53cd\u5e94\u6536\u7387\u51fa\u73b0\u663e\u8457\u964d\u4f4e\u3002\u5e76\u4e14\uff0c\u53cd\u5e94\u8fc7\u7a0b\u4e2d\uff0c\u901a\u8fc7\u9ad8\u6c2f\u9178\u9502\u4ee3\u66ffn<\/em>-Bu4<\/sub>NPF6<\/sub>\u4f5c\u4e3a\u7535\u89e3\u8d28\uff0c\u80fd\u591f\u63d0\u9ad8\u4ea7\u72698<\/strong>\u4e0e10<\/strong>\u7684\u53cd\u5e94\u6536\u7387\u3002\u540c\u65f6\uff0c\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u5bf9\u4e8e1-\u6eb4-3,5-\u4e8c\u7532\u57fa\u82ef\u5e95\u7269\uff0c\u540c\u6837\u80fd\u591f\u4ee561%\u7684\u53cd\u5e94\u6536\u7387\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u82c4\u57fa\u4e59\u9170\u80fa\u4ea7\u726912<\/strong>\u3002<\/p>\n

\u4e4b\u540e\uff0c\u4f5c\u8005\u7814\u7a76\u53d1\u73b0\uff0c\u5176\u5b83\u7c7b\u578b\u7684\u70f7\u57fa\u53d6\u4ee3\u82ef\u884d\u751f\u7269\uff0c\u540c\u6837\u80fd\u591f\u987a\u5229\u5730\u53c2\u4e0e\u4e0a\u8ff0\u7684C-H\u952e\u80fa\u5316\u8fc7\u7a0b\uff0c\u5e76\u83b7\u5f97\u76ee\u6807\u4ea7\u726913<\/strong>\u4e0e14<\/strong>\u3002\u540c\u65f6\uff0c\u4f5c\u8005\u53d1\u73b0\uff0c\u5177\u6709\u652f\u94fe\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u4f8b\u5982\u5f02\u4e19\u82ef\uff0c\u5219\u6700\u7ec8\u83b7\u5f97\u76f8\u5e94\u7684\u4e8c\u6c22\u54aa\u5511\u4ea7\u726915<\/strong>\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5bf9\u4e8e\u5206\u5b50\u4e2d\u540c\u65f6\u5177\u6709\u7532\u57fa\u4e0e\u4e9a\u7532\u57fa\u53d6\u4ee3\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u5728\u53cd\u5e94\u8fc7\u7a0b\u4e2d\uff0c\u5219\u4f18\u5148\u9009\u62e9\u4e9a\u7532\u57fa\u4f4d\u70b9\uff0c\u5e76\u83b7\u5f97\u4ea7\u726916<\/strong>\uff0c\u5176\u533a\u57df\u5f02\u6784\u6bd4\u4e3a6.2:1\u3002\u5e76\u4e14\uff0c\u4f5c\u8005\u89c2\u5bdf\u5230\uff0c\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u5bf9\u4e8e\u4e8c\u82ef\u7532\u70f7\u5e95\u7269\uff0c\u540c\u6837\u80fd\u591f\u4ee5\u826f\u597d\u7684\u53cd\u5e94\u6536\u7387\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u03b1<\/em>-\u4e8c\u82b3\u57fa\u80fa\u4ea7\u726917<\/strong>\u3002\u4e4b\u540e\uff0c\u4f5c\u8005\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u4e00\u7cfb\u5217\u4e0d\u540c\u7c7b\u578b\u7684\u73af\u72b6\u5e95\u7269\uff0c\u4f8b\u5982\u56db\u6c22\u8418\u3001\u831a\u6ee1 (indane)\u4ee5\u53ca\u4e8c\u82ef\u5e76\u8f6f\u6728\u916e (dibenzosuberone)\uff0c\u540c\u6837\u80fd\u591f\u987a\u5229\u5730\u53c2\u4e0a\u8ff0\u7684\u8f6c\u5316\u8fc7\u7a0b\uff0c\u5e76\u83b7\u5f97\u4ea7\u726918<\/strong>–20<\/strong>\u3002<\/p>\n

\u63a5\u4e0b\u6765\uff0c\u4f5c\u8005\u5bf9\u4e0a\u8ff0C-H\u952e\u80fa\u5316\u8fc7\u7a0b\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u8fdb\u884c\u8003\u5bdf\u3002\u7814\u7a76\u8868\u660e\uff0c\u4e0a\u8ff0\u7684\u6807\u51c6\u53cd\u5e94\u6761\u4ef6\u5bf9\u4e8e\u70f7\u57fa\u4fa7\u94fe\u4e2d\u5177\u6709\u9187\u7f9f\u57fa\u3001\u7fa7\u57fa\u3001\u70f7\u6c27\u7fb0\u57fa\u4ee5\u53ca\u5364\u7d20\u7b49\u57fa\u56e2\u53d6\u4ee3\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u5747\u80fd\u591f\u826f\u597d\u5730\u517c\u5bb9\uff0c\u5e76\u83b7\u5f97\u76f8\u5e94\u7684\u80fa\u5316\u4ea7\u726921<\/strong>–26<\/strong>\u3002\u540c\u65f6\uff0c\u5bf9\u4e8e\u70f7\u57fa\u4fa7\u94fe\u4e2d\u5177\u6709\u7aef\u7094\u57fa\u56e2\u53d6\u4ee3\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u5219\u65e0\u6cd5\u6709\u6548\u5730\u8fdb\u884c\u4e0a\u8ff0\u7684C-H\u952e\u80fa\u5316\u8fc7\u7a0b\u3002\u7136\u800c\uff0c\u70f7\u57fa\u4fa7\u94fe\u4e2d\u5177\u6709\u5185\u7094\u57fa\u56e2\u53d6\u4ee3\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u5219\u80fd\u591f\u4ee570%\u7684\u53cd\u5e94\u6536\u7387\uff0c\u83b7\u5f97\u76f8\u5e94\u76ee\u6807\u4ea7\u726928<\/strong>\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\uff0c\u5bf9\u4e8e\u5177\u6709\u4e0d\u540c\u7c7b\u578b\u542b\u6c2e\u5b98\u80fd\u56e2\u53d6\u4ee3\u7684\u82b3\u9999\u65cf\u5316\u5408\u7269\uff0c\u540c\u6837\u80fd\u591f\u6709\u6548\u5730\u517c\u5bb9\uff0c\u5e76\u83b7\u5f97\u76f8\u5e94\u7684C-H\u952e\u80fa\u5316\u4ea7\u726929<\/strong>–34<\/strong>\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u4e3a\u8fdb\u4e00\u6b65\u9610\u660e\u8fd9\u4e00\u5168\u65b0\u7684C-H\u952e\u80fa\u5316\u53cd\u5e94\u7b56\u7565\u7684\u5b9e\u7528\u6027\uff0c\u63a5\u4e0b\u6765\uff0c\u4f5c\u8005\u5bf9\u4e00\u7cfb\u5217\u590d\u6742\u6709\u673a\u5206\u5b50\u8fdb\u884c\u76f8\u5173\u7684\u540e\u671f\u5b98\u80fd\u56e2\u5316\u7814\u7a76\u00a0(Table 3)\u3002\u9996\u5148\uff0c\u8be5\u5c0f\u7ec4\u53d1\u73b0\uff0c\u4e0a\u8ff0\u7684C-H\u952e\u80fa\u5316\u7b56\u7565\u80fd\u591f\u6709\u6548\u5730\u5e94\u7528\u4e8esertraline\u7c7b\u4f3c\u726935<\/strong>\u3001\u89c6\u9ec4\u9178\u53d7\u4f53\u6fc0\u52a8\u5242\u884d\u751f\u7269 (retinoic acid receptor agonist derivative) 36<\/b><\/strong>\u3001\u975b\u7ea2\u884d\u751f\u7269 (isatin derivative) 37<\/strong>\u4ee5\u53caCYP11B1\u6291\u5236\u5242\u884d\u751f\u726938<\/strong>\u7684\u540e\u671f\u5b98\u80fd\u56e2\u5316\u8fc7\u7a0b\uff0c\u5e76\u4ee5\u826f\u597d\u7684\u53cd\u5e94\u6536\u7387\u4e0e\u533a\u57df\u9009\u62e9\u6027\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u76ee\u6807\u4ea7\u7269\u3002\u540c\u65f6\uff0c\u4f5c\u8005\u89c2\u5bdf\u5230\uff0c\u5177\u6709\u9170\u4e9a\u80fa\u4ee5\u53ca\u916e\u7fb0\u57fa\u5b98\u80fd\u56e2\u53d6\u4ee3\u7684\u82b3\u9999\u65cf\u884d\u751f\u7269\uff0c\u540c\u6837\u80fd\u591f\u4e0e\u4e0a\u8ff0\u7684\u6807\u51c6\u53cd\u5e94\u4f53\u7cfb\u826f\u597d\u5730\u517c\u5bb9\uff0c\u5e76\u83b7\u5f97\u76f8\u5e94\u7684\u5b98\u80fd\u56e2\u5316\u4ea7\u726939<\/strong>–41<\/strong>\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fd9\u4e00\u5168\u65b0\u7684C-H\u952e\u80fa\u5316\u65b9\u6cd5\u5b66\u5bf9\u4e8e\u5b58\u5728\u6e38\u79bb\u80fa\u5b98\u80fd\u56e2\u7684\u590d\u6742\u5206\u5b50\uff0c\u540c\u6837\u80fd\u591f\u8f83\u597d\u5730\u8fdb\u884c\u517c\u5bb9\uff0c\u5e76\u83b7\u5f97\u76f8\u5e94\u7684\u80fa\u5316\u4ea7\u726942<\/strong>–44<\/strong>\u3002\u6b64\u5916\uff0c\u8be5\u5c0f\u7ec4\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u5728\u901a\u8fc7\u831a\u6ee1\u5e95\u7269\u8fdb\u884c\u7684\u514b\u7ea7\u89c4\u6a21\u5b9e\u9a8c\u7814\u7a76\u4e2d (1.5 g)\uff0c\u5c06\u53cd\u5e94\u65f6\u95f4\u5ef6\u957f\u81f372 h\uff0c\u540c\u6837\u80fd\u591f\u83b7\u5f9750%\u6536\u7387\u7684\u4ea7\u726941<\/strong>\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u6700\u540e\uff0c\u4f5c\u8005\u63d0\u51fa\u4e00\u79cd\u53ef\u80fd\u7684\u53cd\u5e94\u673a\u7406 (Figure 2)\u3002\u9996\u5148\uff0c\u901a\u8fc7TAC 1<\/strong>\u7684\u6c27\u5316\u8fc7\u7a0b\uff0c\u5f62\u6210\u7a33\u5b9a\u7684\u81ea\u7531\u57fa\u53cc\u6b63\u79bb\u5b5045<\/strong>\u00a0<\/strong>(Ep\/2<\/sub>\u00a0= 1.12 V in 30:1 MeCN:TFA vs SCE)\u3002\u4e4b\u540e\uff0c45<\/strong>\u5728\u5149\u8f90\u5c04\u6761\u4ef6\u4e0b\uff0c\u5f62\u6210\u5149\u6fc0\u53d1\u6001\u4e2d\u95f4\u4f5346<\/strong>\uff0c\u7ee7\u800c\u8fdb\u4e00\u6b65\u53c2\u4e0e\u82b3\u57fa\u5e95\u726947<\/strong>\u7684\u5355\u7535\u5b50\u6c27\u5316\u8fc7\u7a0b\uff0c\u4ea7\u751f\u81ea\u7531\u57fa\u6b63\u79bb\u5b5048<\/strong>\u3002\u5e76\u8fdb\u4e00\u6b65\u901a\u8fc748<\/strong>\u7684\u53bb\u8d28\u5b50\u5316\u6b65\u9aa4\uff0c\u4ea7\u751f\u82c4\u57fa\u81ea\u7531\u57fa49<\/strong>\u3002\u63a5\u4e0b\u6765\uff0c\u82c4\u57fa\u81ea\u7531\u57fa49<\/strong>\u80fd\u591f\u4e0e\u81ea\u7531\u57fa\u53cc\u6b63\u79bb\u5b5045<\/strong>\u6216\u76f4\u63a5\u901a\u8fc7\u9633\u6781\uff0c\u8fdb\u884c\u4e8c\u6b21\u6c27\u5316\u8fc7\u7a0b\uff0c\u5f62\u6210\u78b3\u6b63\u79bb\u5b50\u4e2d\u95f4\u4f5350<\/strong>\u3002\u5e76\u7ee7\u7eed\u901a\u8fc7Ritter\u53cd\u5e94\u8def\u5f84\uff0c\u5f62\u6210\u8148\u6b63\u79bb\u5b50 (nitrilium)\u4e2d\u95f4\u4f5351<\/strong>\u3002\u6700\u7ec8\uff0c\u901a\u8fc751<\/strong>\u7684\u6c34\u89e3\u8fc7\u7a0b\uff0c\u83b7\u5f97\u9170\u80fa\u4ea7\u726952<\/strong>\u3002\u540c\u65f6\uff0c\u901a\u8fc7\u8d28\u5b50\u7684\u9634\u6781\u8fd8\u539f\u4ea7\u751f\u6c22\u6c14\u7684\u53cd\u5e94\u8fc7\u7a0b\uff0c\u8fdb\u800c\u5b9e\u73b0\u76f8\u5173\u6c27\u5316\u8fd8\u539f\u8fc7\u7a0b\u7684\u5e73\u8861\u3002\u540c\u65f6\uff0c\u8fd9\u4e00\u7535\u5316\u5b66\u5149\u50ac\u5316\u7b56\u7565\u8bbe\u8ba1\u7684\u5173\u952e\u5728\u4e8e\u901a\u8fc7\u7535\u89e3\u69fd\u56fa\u6709\u7684\u7535\u6781\u7535\u52bf\uff0c\u65e0\u6cd5\u9996\u5148\u76f8\u5173\u6709\u673a\u5e95\u7269\u7684\u6c27\u5316\uff0c\u56e0\u6b64\uff0c\u9700\u8981\u9009\u62e9\u76f8\u5e94\u7684\u7535\u5316\u5b66\u5149\u50ac\u5316\u5242\uff0c\u8fdb\u800c\u5b9e\u73b0\u9009\u62e9\u6027\u7684\u5355\u7535\u5b50\u6c27\u5316\u8fc7\u7a0b\uff0c\u5e76\u8fdb\u4e00\u6b65\u51cf\u5c11\u526f\u53cd\u5e94\u8fc7\u7a0b\u7684\u53d1\u751f\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u8fdb\u4e00\u6b65\u5047\u8bbe\uff0c\u82c4\u57fa\u4e59\u9170\u80fa52<\/strong>\u7ecf\u5386\u9178\u50ac\u5316\u7684E1\u6d88\u9664\u8fc7\u7a0b\uff0c\u5f62\u6210\u82ef\u4e59\u70ef53<\/strong>\uff0c\u4e4b\u540e\uff0c\u7ecf\u5386\u8fdb\u4e00\u6b65\u7684\u6c27\u5316\u4e0eRitter\u578b\u53cd\u5e94\u8fc7\u7a0b\uff0c\u5f62\u6210\u533a\u57df\u5f02\u6784\u4e8c\u6c22\u54aa\u551154a<\/strong>\u621654b<\/strong>\u3002\u63a5\u4e0b\u6765\uff0c\u4f5c\u8005\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u5728\u82c4\u57fa\u4f4d\u7f6e\u5b58\u5728\u4fa7\u94fe\u7684\u5e95\u7269\u4e2d\uff0c\u901a\u8fc7TFA\uff0c\u80fd\u591f\u66f4\u52a0\u5bb9\u6613\u5730\u4fc3\u8fdb\u6d88\u9664\u8fc7\u7a0b\u7684\u8fdb\u884c\u3002\u56e0\u6b64\uff0c\u5728\u82c4\u57fa\u4f4d\u7f6e\u5b58\u5728\u4fa7\u94fe\u7684\u5e95\u7269\u4e2d\uff0c\u5e76\u672a\u89c2\u5bdf\u5230\u82c4\u57fa\u4e59\u9170\u80fa\u4ea7\u726952<\/strong>\u7684\u5f62\u6210\u3002\u7136\u800c\uff0c\u5728\u82c4\u57fa\u4f4d\u7f6e\u65e0\u4fa7\u94fe\u7684\u5e95\u7269\u4e2d\uff0c\u4e0a\u8ff0\u6d88\u9664\u8fc7\u7a0b\u7684\u8fdb\u884c\uff0c\u5219\u9700\u8981\u9009\u62e9\u9178\u6027\u66f4\u5f3a\u7684\u4e09\u6c1f\u7532\u78fa\u9178\u3002\u56e0\u6b64\uff0c\u5728TFA\u5b58\u5728\u7684\u53cd\u5e94\u6761\u4ef6\u4e0b\uff0c\u4ec5\u80fd\u591f\u5f62\u6210\u82c4\u57fa\u4e59\u9170\u80fa\u4ea7\u726952<\/strong>\u3002\u63a5\u4e0b\u6765\uff0c\u8be5\u5c0f\u7ec4\u901a\u8fc7CV (cyclic\u00a0voltammetry)\u6cd5\u5bf9\u76f8\u5e94\u80fa\u5316\u4ea7\u7269\u7684\u6c27\u5316\u8fd8\u539f\u7535\u52bf\u8fdb\u884c\u6d4b\u5b9a (Table 2)\u3002\u901a\u8fc7\u4e0a\u8ff0\u7684\u6d4b\u5b9a\u8fc7\u7a0b\uff0c\u4f5c\u8005\u53d1\u73b0\uff0c\u76ee\u6807\u4ea7\u7269\u7684\u6c27\u5316\u8fd8\u539f\u7535\u52bf\u4e0e\u8d77\u59cb\u539f\u6599\u6781\u4e3a\u63a5\u8fd1(\u53c2\u9605Supporting<\/u>\u00a0<\/u>Information<\/u><\/a>)\u3002\u5e76\u4e14\uff0c\u4e59\u9170\u6c28\u57fa\u5b98\u80fd\u56e2\u7684\u5f15\u5165\uff0c\u80fd\u591f\u51cf\u6162\u5176\u4e0eT<\/b><\/strong>AC 1<\/b><\/strong>\u4e4b\u95f4\u8fdb\u884c\u5355\u7535\u5b50\u6c27\u5316\u8fc7\u7a0b\u7684\u52a8\u529b\u5b66\u901f\u7387\uff0c\u56e0\u800c\uff0c\u4f7f\u4e0a\u8ff0\u7684\u7535\u5316\u5b66\u5149\u50ac\u5316\u8fc7\u7a0b\u80fd\u591f\u66f4\u4e3a\u6709\u6548\u5730\u8fdb\u884c\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u603b\u7ed3<\/h4>\n

\u7f8e\u56fdCornell\u5927\u5b66\u7684T. H. Lambert\u6559\u6388\u8bfe\u9898\u7ec4\u6210\u529f\u5f00\u53d1\u51fa\u4e00\u79cd\u5168\u65b0\u7684\u7535\u5316\u5b66\u5149\u50ac\u5316Ritter\u578b\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u91c7\u7528\u4e59\u8148\u4f5c\u4e3a\u6c2e\u6e90\uff0c\u5728\u65e0\u76f8\u5e94\u5316\u5b66\u6c27\u5316\u5242\u5b58\u5728\u7684\u6761\u4ef6\u4e0b\uff0c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u82c4\u57fa\u4e59\u9170\u80fa\u5206\u5b50\u7684\u6784\u5efa\u3002\u540c\u65f6\uff0c\u8fd9\u4e00\u5168\u65b0\u7684C-H\u80fa\u5316\u7b56\u7565\u5177\u6709\u826f\u597d\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u4ee5\u53ca\u5e7f\u6cdb\u7684\u5e95\u7269\u5e94\u7528\u8303\u56f4\u7b49\u4f18\u52bf\u3002\u6b64\u5916\uff0c\u901a\u8fc7\u5bf9\u5404\u7c7b\u590d\u6742\u5206\u5b50\u7684\u540e\u671f\u5b98\u80fd\u56e2\u5316\u7814\u7a76\uff0c\u8fdb\u4e00\u6b65\u9610\u660e\u4e0a\u8ff0\u7b56\u7565\u7684\u5408\u6210\u5e94\u7528\u4ef7\u503c\u3002<\/p>\n

\u53c2\u8003\u6587\u732e<\/b><\/strong><\/h4>\n[1]\u00a0E. A. Wappes, S. C. Fosu, T. C. Chopko, D. A.\u00a0Nagib, Angew.<\/i><\/em>\u00a0<\/i><\/em>Chem. Int. Ed.<\/i><\/em>\u00a02016<\/b><\/strong>, 55<\/i><\/em>, 9974.\u00a0doi:\u00a010.1002\/anie.201604704<\/u><\/a>.<\/u><\/p>\n[2]\u00a0C. Martinez, K. Mu\u00f1iz, Angew. Chem. Int. Ed.<\/i><\/em>\u00a02015<\/b><\/strong>, 54<\/i><\/em>, 8287.\u00a0doi:\u00a010.1002\/anie.201501122<\/u><\/a>.<\/u><\/p>\n[3]\u00a0P. Becker, T. Duhamel, C. J. Stein, M. Reiher, K.\u00a0Mu\u00f1iz,\u00a0Angew. Chem. Int. Ed. <\/i><\/em>2017<\/b><\/strong>, 56<\/i><\/em>, 8004.\u00a0doi:\u00a010.1002\/anie.201703611<\/u><\/a>.<\/u><\/p>\n[4]\u00a0Q. Michaudel, D. Thevenet, P. S. Baran, J. Am. Chem.<\/em>\u00a0<\/em>Soc.<\/em>\u00a02012<\/strong>, 134<\/em>, 2547.\u00a0doi:\u00a010.1021\/ja212020b<\/u><\/a>.<\/u><\/p>\n[5]\u00a0K. Kiyokawa, K. Takemoto, S. Minakata, Chem. Commun.<\/em>\u00a02016<\/strong>, 52<\/em>, 13082-13085.\u00a0doi:\u00a010.1039\/C6CC07164C<\/u><\/a>.<\/u><\/p>\n[6]\u00a0S. Sakaguchi, T. Hirabayashi, Y. Ishii, Chem.<\/em>\u00a0<\/em>Commun.<\/em>2002<\/strong>, 5<\/em>, 516-517.\u00a0doi:\u00a010.1039\/B110638D<\/u><\/a>.<\/u><\/p>\n[7]\u00a0G. Li, C. A. Morales-Rivera, F. Gao, Y. Wang, G. He, P. Liu,\u00a0G. Chen, Chem. Sci.<\/em>\u00a02017<\/strong>, 8<\/em>, 7180.\u00a0doi:\u00a010.1039\/C7SC02773G<\/u><\/a>.<\/u><\/p>\n[8]\u00a0J. Y. Becker, L. R. Byrd, L. L. Miller, Y.-H. So, J. Am. Chem. Soc. <\/em>1975<\/strong>, 97<\/em>, 853.\u00a0doi:\u00a010.1021\/ja00837a027<\/u><\/a>.<\/u><\/p>\n[9]\u00a0J. Y. Becker, L. R. Byrd, L. L. Miller, J. Am. Chem.<\/em>\u00a0<\/em>Soc.<\/em>\u00a01974<\/strong>, 96<\/em>, 4718.\u00a0doi:\u00a010.1021\/ja00821a083<\/u><\/a>.<\/u><\/p>\n[10]\u00a0J. Y. Becker, L. L. Miller, T. M. Siegel, J. Am. Chem. Soc.<\/em>\u00a01975<\/strong>, 97<\/em>, 849.\u00a0doi:\u00a010.1021\/ja00837a026<\/u><\/a>.<\/u><\/p>\n[11]\u00a0T. Tajima, H. Ishii, T. Fuchigami, Electrochem.Commun.<\/em>\u00a02002<\/strong>, 4<\/em>, 589.\u00a0doi:\u00a010.1016\/S1388-2481(02)00381-8<\/u><\/a>.<\/u><\/p>\n[12] T. Shen, T. H. Lambert, Science<\/i><\/em>\u00a02021<\/b><\/strong>,\u00a0371<\/i><\/em>, 620. doi:\u00a010.1126\/science.abf2798<\/u><\/a>.<\/u><\/p>\n

 <\/p>\n

\u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0Chem-Station\u5316\u5b66\u7a7a\u95f4<\/a>\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d\uff01<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"\u672c\u6587\u4f5c\u8005\uff1a\u6749\u6749 \u5bfc\u8bfb \u8fd1\u671f\uff0c\u7f8e\u56fdCornell\u5927\u5b66T.\u00a0H. Lambert\u6559\u6388\u8bfe\u9898\u7ec4\u5728JACS\u4e2d\u53d1\u8868\u8bba\u6587\uff0c\u62a5\u9053\u4e00\u79cd\u901a\u8fc7\u7535\u5316\u5b66\u5149\u50ac\u5316\u7684Ritter\u578b\u53cd\u5e94\u65b9\u6cd5\u5b66\u8fdb\u884c\u7684C-H\u952e\u80fa\u5316\u7814\u7a76\u3002\u8fd9\u4e00\u5168\u65b0\u7684C-H\u952e\u80fa\u5316\u7b56\u7565\u4e2d\u91c7\u7528TAC\u79bb\u5b50\u00a0(trisaminocyclopropenium ion) \u4f5c\u4e3a\u50ac\u5316\u5242\uff0c\u5728\u5149\u8f90\u5c04\u4ee5\u53ca\u7535\u5316\u5b66\u53cd\u5e94\u6761\u4ef6\u4e0b\uff0c\u80fd\u591f\u6210\u529f\u5730\u5728\u76f8\u5e94\u7684\u82c4\u4f4dC-H\u952e\u4e2d\u5f15\u5165\u4e59\u9170\u6c28\u57fa\u5b98\u80fd\u56e2\u3002\u540c\u65f6\uff0c\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u65e0\u9700\u9009\u62e9\u5316\u5b66\u8ba1\u91cf\u7684\u5404\u7c7b\u5316\u5b66\u6c27\u5316\u5242\u3002\u5e76\u4e14\uff0c\u8fd9\u4e00\u5168\u65b0\u7684C-H\u952e\u80fa\u5316\u7b56\u7565\u5177\u6709\u826f\u597d\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u3001\u5e7f\u6cdb\u7684\u5e95\u7269\u5e94\u7528\u8303\u56f4\u7b49\u4f18\u52bf\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u901a\u8fc7\u5bf9\u4e8e\u5404\u7c7b\u590d\u6742\u5206\u5b50\u540e\u671f\u884d\u751f\u5316\u8fc7\u7a0b\u7684\u7814\u7a76\uff0c\u8fdb\u4e00\u6b65\u9610\u660e\u8fd9\u4e00\u7b56\u7565\u7684\u5408\u6210\u5b9e\u7528\u6027\u3002 C-H Amination via Electrophotocatalytic Ritter-type Reaction T. Shen, T. H. Lambert, J. Am. Chem. Soc. 2021, 143, 8597. doi:10.1021\/jacs.1c03718. \u6b63\u6587 \u5c06\u672a\u6d3b\u5316\u7684C-H\u952e\u8f6c\u5316\u4e3aC-N\u952e\u7684\u53cd\u5e94\u7b56\u7565\u4f5c\u4e3a\u6709\u673a\u5408\u6210\u9886\u57df\u7684\u7814\u7a76\u70ed\u70b9\uff0c\u4e00\u76f4\u4ee5\u6765\u5907\u53d7\u5e7f\u6cdb\u5173\u6ce8\u3002\u5176\u4e2d\uff0cHoffmann-L\u00f6fler-Freitag\u53cd\u5e94\u65b9\u6cd5\u5b66\u5df2\u7ecf\u6210\u4e3a\u6784\u5efa\u590d\u6742\u5206\u5b50\u7684\u5173\u952e\u53cd\u5e94\u4e4b\u4e00\u3002\u5e76\u4e14\uff0c\u8fd1\u5e74\u6765\uff0c\u901a\u5e38\u91c7\u7528\u5149\u6c27\u5316\u8fd8\u539f\u50ac\u5316\u7684\u7b56\u7565\uff0c\u8fdb\u884cHoffmann-L\u00f6fler-Freitag\u53cd\u5e94\u7684\u76f8\u5173\u7814\u7a76[1]–[3]\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u901a\u8fc7\u6c2e\u70ef\u4e2d\u95f4\u4f53\u53c2\u4e0e\u7684\u4e00\u7cfb\u5217\u5408\u6210\u8f6c\u5316\u8fc7\u7a0b\uff0c\u540c\u6837\u80fd\u591f\u6709\u6548\u5730\u5b8c\u6210\u76f8\u5e94C-N\u952e\u7684\u6784\u5efa\u3002\u6b64\u5916\uff0c\u91c7\u7528\u8fc7\u6e21\u91d1\u5c5e\u914d\u5408\u7269\u53c2\u4e0e\u7684C-N\u5076\u8054\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u540c\u6837\u5907\u53d7\u5173\u6ce8\u3002\u540c\u65f6\uff0c\u5408\u6210\u5316\u5b66\u5bb6\u8fdb\u4e00\u6b65\u8bbe\u8ba1\u51fa\u4e00\u79cd\u65b0\u578b\u7684\u53cd\u5e94\u7b56\u7565\uff0c\u5c06C-H\u952e\u6c27\u5316\uff0c\u4ea7\u751f\u76f8\u5e94\u7684\u78b3\u6b63\u79bb\u5b50\uff0c\u5e76\u901a\u8fc7\u8148\u5206\u5b50\u7684\u6355\u83b7\uff0c\u6700\u7ec8\u83b7\u5f97\u4e00\u7cfb\u5217\u9170\u80fa\u4ea7\u7269 (Figure 1a)\u3002\u8fd9\u4e00\u7b56\u7565\u7684\u672c\u8d28\u4e3aRitter\u53cd\u5e94\u3002\u7136\u800c\uff0c\u4e0d\u540c\u4e4b\u5904\u5219\u5728\u4e8e\u78b3\u6b63\u79bb\u5b50\u7684\u5f62\u6210\u65b9\u5f0f\u3002\u76ee\u524d\uff0c\u50ac\u5316Ritter\u578bC-H\u80fa\u5316\u7b56\u7565\u5df2\u7ecf\u53d6\u5f97\u8bf8\u591a\u7684\u7814\u7a76\u8fdb\u5c55[4]–[7]\u00a0(Figure 1b)\u3002\u7136\u800c\uff0c\u5374\u5b58\u5728\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u9009\u62e9\u7684\u6c27\u5316\u5242\u4e0e\u5e95\u7269\u4e2d\u7684\u8bf8\u591a\u5b98\u80fd\u56e2\u65e0\u6cd5\u517c\u5bb9\u7684\u95ee\u9898\u3002\u7531\u6b64\uff0c\u4f5c\u8005\u8bbe\u60f3\uff0c\u8bbe\u8ba1\u4e00\u79cd\u65e0\u9700\u9009\u62e9\u5316\u5b66\u6c27\u5316\u5242\u7684\u7535\u5316\u5b66\u53cd\u5e94\u7b56\u7565\uff0c\u5219\u80fd\u591f\u6709\u6548\u5730\u89e3\u51b3\u4e0a\u8ff0\u7b56\u7565\u4e2d\u5b58\u5728\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u95ee\u9898\u3002\u5e76\u4e14\uff0c\u901a\u8fc7\u7535\u5316\u5b66\u65b9\u5f0f\u5b9e\u73b0\u7684Ritter\u578bC-H\u80fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u540c\u6837\u6709\u8bf8\u591a\u7684\u6587\u732e\u62a5\u9053[8]–[11]\u3002\u7136\u800c\uff0c\u5728\u4e0a\u8ff0\u7684\u7535\u5316\u5b66\u53cd\u5e94\u65b9\u6848\u4e2d\uff0c\u901a\u5e38\u9700\u8981\u8f83\u9ad8\u7684\u9633\u6781\u7535\u52bf\uff0c\u56e0\u800c\uff0c\u65e0\u6cd5\u83b7\u5f97\u8f83\u9ad8\u7684\u53cd\u5e94\u6536\u7387\u3002\u5e76\u4e14\uff0c\u4e0e\u5e95\u7269\u4e2d\u5b58\u5728\u7684\u591a\u79cd\u5b98\u80fd\u56e2\u540c\u6837\u65e0\u6cd5\u6709\u6548\u5730\u8fdb\u884c\u517c\u5bb9\u3002\u4e3a\u8fdb\u4e00\u6b65\u89e3\u51b3\u4e0a\u8ff0\u7535\u5316\u5b66\u7b56\u7565\u4e2d\u5b58\u5728\u7684\u76f8\u5173\u95ee\u9898\uff0c\u8fd1\u671f\uff0c\u672c\u8bfe\u9898\u5df2\u7ecf\u6210\u529f\u8bbe\u8ba1\u51fa\u4e00\u79cd\u901a\u8fc7\u7535\u5316\u5b66\u5149\u50ac\u5316\u6761\u4ef6\u4fc3\u8fdb\u7684C-H\u53cc\u80fa\u5316\u00a0(C-H diamination)\u53cd\u5e94\u65b9\u6cd5\u5b66 (Figure 1c)[12]\u3002\u53d7\u4e0a\u8ff0\u7814\u7a76\u7684\u542f\u53d1\uff0c\u8fd9\u91cc\uff0c\u672c\u6587\u5c06\u62a5\u9053\u4e00\u79cd\u7535\u5316\u5b66\u5149\u50ac\u5316\u7684Ritter\u578b\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u5728\u82c4\u57fa\u4f4d\u7f6e\u5f15\u5165\u76f8\u5e94\u7684\u4e59\u9170\u6c28\u57fa\u5b98\u80fd\u56e2\u3002\u540c\u65f6\uff0c\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u65e0\u9700\u91c7\u7528\u5316\u5b66\u8ba1\u91cf\u7684\u5404\u7c7b\u5316\u5b66\u6c27\u5316\u5242 (Figure 1c)\u3002   \u9996\u5148\uff0c\u4f5c\u8005\u91c7\u75282\u4f5c\u4e3a\u6a21\u578b\u5e95\u7269\uff0c\u8fdb\u884c\u76f8\u5173\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316\u7b5b\u9009 (Table 1)\u3002\u8fdb\u800c\u786e\u5b9a\u6700\u4f73\u7684\u53cd\u5e94\u6761\u4ef6\u4e3a\uff1a\u91c7\u75288 mol%\u00a0TAC 1\u4f5c\u4e3a\u50ac\u5316\u5242\uff0cn-Bu4NPF6\u4f5c\u4e3a\u7535\u89e3\u8d28\uff0c\u9009\u62e9\u78b3\u6be1\u9633\u6781 (carbon felt anode)\u4e0e\u94c2\u9634\u6781\uff0c\u4e59\u8148\u4f5c\u4e3a\u53cd\u5e94\u6eb6\u5242\uff0c\u540c\u65f6\u52a0\u5165TFA\u4e0e\u6c34\uff0c\u5728H\u578b\u9694\u819c\u7535\u89e3\u69fd (H-type divided cell,\u00a0Ecell\u00a0= 2.2 V, Eanode\u00a0= 1.6 V vs SCE)\u4ee5\u53ca\u901a\u8fc7CFL (compact fluorescent light)\u63d0\u4f9b\u7684\u53ef\u89c1\u5149\u8f90\u5c04\u6761\u4ef6\u4e0b\u8fdb\u884c\u53cd\u5e94\uff0c\u6700\u7ec8\u83b7\u5f97\u76f8\u5e94\u7684\u4e59\u9170\u80fa\u4ea7\u72693\uff0c\u6536\u7387\u4e3a77%\u3002 H-type divided cell Set up the H-type divided cell with the CFL \u5728\u83b7\u5f97\u4e0a\u8ff0\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u4e4b\u540e\uff0c\u4f5c\u8005\u5f00\u59cb\u5bf9\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u7684\u5e95\u7269\u5e94\u7528\u8303\u56f4\u8fdb\u884c\u7814\u7a76 (Table 2)\u3002\u8be5\u5c0f\u7ec4\u53d1\u73b0\uff0c\u4e0a\u8ff0\u7684\u6807\u51c6\u53cd\u5e94\u6761\u4ef6\u5bf9\u4e8e\u7532\u82ef\u4e0e4-\u5364\u4ee3\u7532\u82ef\u5e95\u7269\uff0c\u5747\u80fd\u591f\u4ee5\u826f\u597d\u7684\u53cd\u5e94\u6536\u7387\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u82c4\u57fa\u4e59\u9170\u80fa\u4ea7\u72695–9\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8be5\u5c0f\u7ec4\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u5e95\u7269\u4e2d\u5364\u7d20\u53d6\u4ee3\u57fa\u56e2\u7684\u4f4d\u7f6e\uff0c\u5bf9\u4e8e\u53cd\u5e94\u6536\u7387\u5177\u6709\u8f83\u4e3a\u663e\u8457\u7684\u5f71\u54cd\uff0c\u5176\u4e2d\uff0c\u4e0e4-\u6eb4\u4ee3\u4ea7\u72698\u7684\u53cd\u5e94\u6536\u7387\u76f8\u6bd4\uff0c\u800c2-\u6eb4\u4ee3\u4ea7\u726910\u4e0e3-\u6eb4\u4ee3\u4ea7\u726911\u7684\u53cd\u5e94\u6536\u7387\u51fa\u73b0\u663e\u8457\u964d\u4f4e\u3002\u5e76\u4e14\uff0c\u53cd\u5e94\u8fc7\u7a0b\u4e2d\uff0c\u901a\u8fc7\u9ad8\u6c2f\u9178\u9502\u4ee3\u66ffn-Bu4NPF6\u4f5c\u4e3a\u7535\u89e3\u8d28\uff0c\u80fd\u591f\u63d0\u9ad8\u4ea7\u72698\u4e0e10\u7684\u53cd\u5e94\u6536\u7387\u3002\u540c\u65f6\uff0c\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u5bf9\u4e8e1-\u6eb4-3,5-\u4e8c\u7532\u57fa\u82ef\u5e95\u7269\uff0c\u540c\u6837\u80fd\u591f\u4ee561%\u7684\u53cd\u5e94\u6536\u7387\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u82c4\u57fa\u4e59\u9170\u80fa\u4ea7\u726912\u3002 \u4e4b\u540e\uff0c\u4f5c\u8005\u7814\u7a76\u53d1\u73b0\uff0c\u5176\u5b83\u7c7b\u578b\u7684\u70f7\u57fa\u53d6\u4ee3\u82ef\u884d\u751f\u7269\uff0c\u540c\u6837\u80fd\u591f\u987a\u5229\u5730\u53c2\u4e0e\u4e0a\u8ff0\u7684C-H\u952e\u80fa\u5316\u8fc7\u7a0b\uff0c\u5e76\u83b7\u5f97\u76ee\u6807\u4ea7\u726913\u4e0e14\u3002\u540c\u65f6\uff0c\u4f5c\u8005\u53d1\u73b0\uff0c\u5177\u6709\u652f\u94fe\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u4f8b\u5982\u5f02\u4e19\u82ef\uff0c\u5219\u6700\u7ec8\u83b7\u5f97\u76f8\u5e94\u7684\u4e8c\u6c22\u54aa\u5511\u4ea7\u726915\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5bf9\u4e8e\u5206\u5b50\u4e2d\u540c\u65f6\u5177\u6709\u7532\u57fa\u4e0e\u4e9a\u7532\u57fa\u53d6\u4ee3\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u5728\u53cd\u5e94\u8fc7\u7a0b\u4e2d\uff0c\u5219\u4f18\u5148\u9009\u62e9\u4e9a\u7532\u57fa\u4f4d\u70b9\uff0c\u5e76\u83b7\u5f97\u4ea7\u726916\uff0c\u5176\u533a\u57df\u5f02\u6784\u6bd4\u4e3a6.2:1\u3002\u5e76\u4e14\uff0c\u4f5c\u8005\u89c2\u5bdf\u5230\uff0c\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u5bf9\u4e8e\u4e8c\u82ef\u7532\u70f7\u5e95\u7269\uff0c\u540c\u6837\u80fd\u591f\u4ee5\u826f\u597d\u7684\u53cd\u5e94\u6536\u7387\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u03b1-\u4e8c\u82b3\u57fa\u80fa\u4ea7\u726917\u3002\u4e4b\u540e\uff0c\u4f5c\u8005\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u4e00\u7cfb\u5217\u4e0d\u540c\u7c7b\u578b\u7684\u73af\u72b6\u5e95\u7269\uff0c\u4f8b\u5982\u56db\u6c22\u8418\u3001\u831a\u6ee1 (indane)\u4ee5\u53ca\u4e8c\u82ef\u5e76\u8f6f\u6728\u916e (dibenzosuberone)\uff0c\u540c\u6837\u80fd\u591f\u987a\u5229\u5730\u53c2\u4e0a\u8ff0\u7684\u8f6c\u5316\u8fc7\u7a0b\uff0c\u5e76\u83b7\u5f97\u4ea7\u726918–20\u3002 \u63a5\u4e0b\u6765\uff0c\u4f5c\u8005\u5bf9\u4e0a\u8ff0C-H\u952e\u80fa\u5316\u8fc7\u7a0b\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u8fdb\u884c\u8003\u5bdf\u3002\u7814\u7a76\u8868\u660e\uff0c\u4e0a\u8ff0\u7684\u6807\u51c6\u53cd\u5e94\u6761\u4ef6\u5bf9\u4e8e\u70f7\u57fa\u4fa7\u94fe\u4e2d\u5177\u6709\u9187\u7f9f\u57fa\u3001\u7fa7\u57fa\u3001\u70f7\u6c27\u7fb0\u57fa\u4ee5\u53ca\u5364\u7d20\u7b49\u57fa\u56e2\u53d6\u4ee3\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u5747\u80fd\u591f\u826f\u597d\u5730\u517c\u5bb9\uff0c\u5e76\u83b7\u5f97\u76f8\u5e94\u7684\u80fa\u5316\u4ea7\u726921–26\u3002\u540c\u65f6\uff0c\u5bf9\u4e8e\u70f7\u57fa\u4fa7\u94fe\u4e2d\u5177\u6709\u7aef\u7094\u57fa\u56e2\u53d6\u4ee3\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u5219\u65e0\u6cd5\u6709\u6548\u5730\u8fdb\u884c\u4e0a\u8ff0\u7684C-H\u952e\u80fa\u5316\u8fc7\u7a0b\u3002\u7136\u800c\uff0c\u70f7\u57fa\u4fa7\u94fe\u4e2d\u5177\u6709\u5185\u7094\u57fa\u56e2\u53d6\u4ee3\u7684\u70f7\u57fa\u82ef\u5e95\u7269\uff0c\u5219\u80fd\u591f\u4ee570%\u7684\u53cd\u5e94\u6536\u7387\uff0c\u83b7\u5f97\u76f8\u5e94\u76ee\u6807\u4ea7\u726928\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\uff0c\u5bf9\u4e8e\u5177\u6709\u4e0d\u540c\u7c7b\u578b\u542b\u6c2e\u5b98\u80fd\u56e2\u53d6\u4ee3\u7684\u82b3\u9999\u65cf\u5316\u5408\u7269\uff0c\u540c\u6837\u80fd\u591f\u6709\u6548\u5730\u517c\u5bb9\uff0c\u5e76\u83b7\u5f97\u76f8\u5e94\u7684C-H\u952e\u80fa\u5316\u4ea7\u726929–34\u3002 \u4e3a\u8fdb\u4e00\u6b65\u9610\u660e\u8fd9\u4e00\u5168\u65b0\u7684C-H\u952e\u80fa\u5316\u53cd\u5e94\u7b56\u7565\u7684\u5b9e\u7528\u6027\uff0c\u63a5\u4e0b\u6765\uff0c\u4f5c\u8005\u5bf9\u4e00\u7cfb\u5217\u590d\u6742\u6709\u673a\u5206\u5b50\u8fdb\u884c\u76f8\u5173\u7684\u540e\u671f\u5b98\u80fd\u56e2\u5316\u7814\u7a76\u00a0(Table 3)\u3002\u9996\u5148\uff0c\u8be5\u5c0f\u7ec4\u53d1\u73b0\uff0c\u4e0a\u8ff0\u7684C-H\u952e\u80fa\u5316\u7b56\u7565\u80fd\u591f\u6709\u6548\u5730\u5e94\u7528\u4e8esertraline\u7c7b\u4f3c\u726935\u3001\u89c6\u9ec4\u9178\u53d7\u4f53\u6fc0\u52a8\u5242\u884d\u751f\u7269 (retinoic acid receptor agonist derivative) 36\u3001\u975b\u7ea2\u884d\u751f\u7269 (isatin derivative) 37\u4ee5\u53caCYP11B1\u6291\u5236\u5242\u884d\u751f\u726938\u7684\u540e\u671f\u5b98\u80fd\u56e2\u5316\u8fc7\u7a0b\uff0c\u5e76\u4ee5\u826f\u597d\u7684\u53cd\u5e94\u6536\u7387\u4e0e\u533a\u57df\u9009\u62e9\u6027\uff0c\u83b7\u5f97\u76f8\u5e94\u7684\u76ee\u6807\u4ea7\u7269\u3002\u540c\u65f6\uff0c\u4f5c\u8005\u89c2\u5bdf\u5230\uff0c\u5177\u6709\u9170\u4e9a\u80fa\u4ee5\u53ca\u916e\u7fb0\u57fa\u5b98\u80fd\u56e2\u53d6\u4ee3\u7684\u82b3\u9999\u65cf\u884d\u751f\u7269\uff0c\u540c\u6837\u80fd\u591f\u4e0e\u4e0a\u8ff0\u7684\u6807\u51c6\u53cd\u5e94\u4f53\u7cfb\u826f\u597d\u5730\u517c\u5bb9\uff0c\u5e76\u83b7\u5f97\u76f8\u5e94\u7684\u5b98\u80fd\u56e2\u5316\u4ea7\u726939–41\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fd9\u4e00\u5168\u65b0\u7684C-H\u952e\u80fa\u5316\u65b9\u6cd5\u5b66\u5bf9\u4e8e\u5b58\u5728\u6e38\u79bb\u80fa\u5b98\u80fd\u56e2\u7684\u590d\u6742\u5206\u5b50\uff0c\u540c\u6837\u80fd\u591f\u8f83\u597d\u5730\u8fdb\u884c\u517c\u5bb9\uff0c\u5e76\u83b7\u5f97\u76f8\u5e94\u7684\u80fa\u5316\u4ea7\u726942–44\u3002\u6b64\u5916\uff0c\u8be5\u5c0f\u7ec4\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u5728\u901a\u8fc7\u831a\u6ee1\u5e95\u7269\u8fdb\u884c\u7684\u514b\u7ea7\u89c4\u6a21\u5b9e\u9a8c\u7814\u7a76\u4e2d (1.5 g)\uff0c\u5c06\u53cd\u5e94\u65f6\u95f4\u5ef6\u957f\u81f372 h\uff0c\u540c\u6837\u80fd\u591f\u83b7\u5f9750%\u6536\u7387\u7684\u4ea7\u726941\u3002 \u6700\u540e\uff0c\u4f5c\u8005\u63d0\u51fa\u4e00\u79cd\u53ef\u80fd\u7684\u53cd\u5e94\u673a\u7406 (Figure 2)\u3002\u9996\u5148\uff0c\u901a\u8fc7TAC 1\u7684\u6c27\u5316\u8fc7\u7a0b\uff0c\u5f62\u6210\u7a33\u5b9a\u7684\u81ea\u7531\u57fa\u53cc\u6b63\u79bb\u5b5045\u00a0(Ep\/2\u00a0= 1.12 V in 30:1 MeCN:TFA vs SCE)\u3002\u4e4b\u540e\uff0c45\u5728\u5149\u8f90\u5c04\u6761\u4ef6\u4e0b\uff0c\u5f62\u6210\u5149\u6fc0\u53d1\u6001\u4e2d\u95f4\u4f5346\uff0c\u7ee7\u800c\u8fdb\u4e00\u6b65\u53c2\u4e0e\u82b3\u57fa\u5e95\u726947\u7684\u5355\u7535\u5b50\u6c27\u5316\u8fc7\u7a0b\uff0c\u4ea7\u751f\u81ea\u7531\u57fa\u6b63\u79bb\u5b5048\u3002\u5e76\u8fdb\u4e00\u6b65\u901a\u8fc748\u7684\u53bb\u8d28\u5b50\u5316\u6b65\u9aa4\uff0c\u4ea7\u751f\u82c4\u57fa\u81ea\u7531\u57fa49\u3002\u63a5\u4e0b\u6765\uff0c\u82c4\u57fa\u81ea\u7531\u57fa49\u80fd\u591f\u4e0e\u81ea\u7531\u57fa\u53cc\u6b63\u79bb\u5b5045\u6216\u76f4\u63a5\u901a\u8fc7\u9633\u6781\uff0c\u8fdb\u884c\u4e8c\u6b21\u6c27\u5316\u8fc7\u7a0b\uff0c\u5f62\u6210\u78b3\u6b63\u79bb\u5b50\u4e2d\u95f4\u4f5350\u3002\u5e76\u7ee7\u7eed\u901a\u8fc7Ritter\u53cd\u5e94\u8def\u5f84\uff0c\u5f62\u6210\u8148\u6b63\u79bb\u5b50 (nitrilium)\u4e2d\u95f4\u4f5351\u3002\u6700\u7ec8\uff0c\u901a\u8fc751\u7684\u6c34\u89e3\u8fc7\u7a0b\uff0c\u83b7\u5f97\u9170\u80fa\u4ea7\u726952\u3002\u540c\u65f6\uff0c\u901a\u8fc7\u8d28\u5b50\u7684\u9634\u6781\u8fd8\u539f\u4ea7\u751f\u6c22\u6c14\u7684\u53cd\u5e94\u8fc7\u7a0b\uff0c\u8fdb\u800c\u5b9e\u73b0\u76f8\u5173\u6c27\u5316\u8fd8\u539f\u8fc7\u7a0b\u7684\u5e73\u8861\u3002\u540c\u65f6\uff0c\u8fd9\u4e00\u7535\u5316\u5b66\u5149\u50ac\u5316\u7b56\u7565\u8bbe\u8ba1\u7684\u5173\u952e\u5728\u4e8e\u901a\u8fc7\u7535\u89e3\u69fd\u56fa\u6709\u7684\u7535\u6781\u7535\u52bf\uff0c\u65e0\u6cd5\u9996\u5148\u76f8\u5173\u6709\u673a\u5e95\u7269\u7684\u6c27\u5316\uff0c\u56e0\u6b64\uff0c\u9700\u8981\u9009\u62e9\u76f8\u5e94\u7684\u7535\u5316\u5b66\u5149\u50ac\u5316\u5242\uff0c\u8fdb\u800c\u5b9e\u73b0\u9009\u62e9\u6027\u7684\u5355\u7535\u5b50\u6c27\u5316\u8fc7\u7a0b\uff0c\u5e76\u8fdb\u4e00\u6b65\u51cf\u5c11\u526f\u53cd\u5e94\u8fc7\u7a0b\u7684\u53d1\u751f\u3002\u6b64\u5916\uff0c\u4f5c\u8005\u8fdb\u4e00\u6b65\u5047\u8bbe\uff0c\u82c4\u57fa\u4e59\u9170\u80fa52\u7ecf\u5386\u9178\u50ac\u5316\u7684E1\u6d88\u9664\u8fc7\u7a0b\uff0c\u5f62\u6210\u82ef\u4e59\u70ef53\uff0c\u4e4b\u540e\uff0c\u7ecf\u5386\u8fdb\u4e00\u6b65\u7684\u6c27\u5316\u4e0eRitter\u578b\u53cd\u5e94\u8fc7\u7a0b\uff0c\u5f62\u6210\u533a\u57df\u5f02\u6784\u4e8c\u6c22\u54aa\u551154a\u621654b\u3002\u63a5\u4e0b\u6765\uff0c\u4f5c\u8005\u8fdb\u4e00\u6b65\u53d1\u73b0\uff0c\u5728\u82c4\u57fa\u4f4d\u7f6e\u5b58\u5728\u4fa7\u94fe\u7684\u5e95\u7269\u4e2d\uff0c\u901a\u8fc7TFA\uff0c\u80fd\u591f\u66f4\u52a0\u5bb9\u6613\u5730\u4fc3\u8fdb\u6d88\u9664\u8fc7\u7a0b\u7684\u8fdb\u884c\u3002\u56e0\u6b64\uff0c\u5728\u82c4\u57fa\u4f4d\u7f6e\u5b58\u5728\u4fa7\u94fe\u7684\u5e95\u7269\u4e2d\uff0c\u5e76\u672a\u89c2\u5bdf\u5230\u82c4\u57fa\u4e59\u9170\u80fa\u4ea7\u726952\u7684\u5f62\u6210\u3002\u7136\u800c\uff0c\u5728\u82c4\u57fa\u4f4d\u7f6e\u65e0\u4fa7\u94fe\u7684\u5e95\u7269\u4e2d\uff0c\u4e0a\u8ff0\u6d88\u9664\u8fc7\u7a0b\u7684\u8fdb\u884c\uff0c\u5219\u9700\u8981\u9009\u62e9\u9178\u6027\u66f4\u5f3a\u7684\u4e09\u6c1f\u7532\u78fa\u9178\u3002\u56e0\u6b64\uff0c\u5728TFA\u5b58\u5728\u7684\u53cd\u5e94\u6761\u4ef6\u4e0b\uff0c\u4ec5\u80fd\u591f\u5f62\u6210\u82c4\u57fa\u4e59\u9170\u80fa\u4ea7\u726952\u3002\u63a5\u4e0b\u6765\uff0c\u8be5\u5c0f\u7ec4\u901a\u8fc7CV (cyclic\u00a0voltammetry)\u6cd5\u5bf9\u76f8\u5e94\u80fa\u5316\u4ea7\u7269\u7684\u6c27\u5316\u8fd8\u539f\u7535\u52bf\u8fdb\u884c\u6d4b\u5b9a (Table 2)\u3002\u901a\u8fc7\u4e0a\u8ff0\u7684\u6d4b\u5b9a\u8fc7\u7a0b\uff0c\u4f5c\u8005\u53d1\u73b0\uff0c\u76ee\u6807\u4ea7\u7269\u7684\u6c27\u5316\u8fd8\u539f\u7535\u52bf\u4e0e\u8d77\u59cb\u539f\u6599\u6781\u4e3a\u63a5\u8fd1(\u53c2\u9605Supporting\u00a0Information)\u3002\u5e76\u4e14\uff0c\u4e59\u9170\u6c28\u57fa\u5b98\u80fd\u56e2\u7684\u5f15\u5165\uff0c\u80fd\u591f\u51cf\u6162\u5176\u4e0eTAC 1\u4e4b\u95f4\u8fdb\u884c\u5355\u7535\u5b50\u6c27\u5316\u8fc7\u7a0b\u7684\u52a8\u529b\u5b66\u901f\u7387\uff0c\u56e0\u800c\uff0c\u4f7f\u4e0a\u8ff0\u7684\u7535\u5316\u5b66\u5149\u50ac\u5316\u8fc7\u7a0b\u80fd\u591f\u66f4\u4e3a\u6709\u6548\u5730\u8fdb\u884c\u3002 \u603b\u7ed3 \u7f8e\u56fdCornell\u5927\u5b66\u7684T. H. Lambert\u6559\u6388\u8bfe\u9898\u7ec4\u6210\u529f\u5f00\u53d1\u51fa\u4e00\u79cd\u5168\u65b0\u7684\u7535\u5316\u5b66\u5149\u50ac\u5316Ritter\u578b\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u91c7\u7528\u4e59\u8148\u4f5c\u4e3a\u6c2e\u6e90\uff0c\u5728\u65e0\u76f8\u5e94\u5316\u5b66\u6c27\u5316\u5242\u5b58\u5728\u7684\u6761\u4ef6\u4e0b\uff0c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u82c4\u57fa\u4e59\u9170\u80fa\u5206\u5b50\u7684\u6784\u5efa\u3002\u540c\u65f6\uff0c\u8fd9\u4e00\u5168\u65b0\u7684C-H\u80fa\u5316\u7b56\u7565\u5177\u6709\u826f\u597d\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u4ee5\u53ca\u5e7f\u6cdb\u7684\u5e95\u7269\u5e94\u7528\u8303\u56f4\u7b49\u4f18\u52bf\u3002\u6b64\u5916\uff0c\u901a\u8fc7\u5bf9\u5404\u7c7b\u590d\u6742\u5206\u5b50\u7684\u540e\u671f\u5b98\u80fd\u56e2\u5316\u7814\u7a76\uff0c\u8fdb\u4e00\u6b65\u9610\u660e\u4e0a\u8ff0\u7b56\u7565\u7684\u5408\u6210\u5e94\u7528\u4ef7\u503c\u3002 […]","protected":false},"author":26,"featured_media":40204,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1271],"tags":[3603,3602,3542],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2021\/09\/1-23.png","jetpack_shortlink":"https:\/\/wp.me\/p96op1-ars","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/40142"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/26"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=40142"}],"version-history":[{"count":2,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/40142\/revisions"}],"predecessor-version":[{"id":40288,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/40142\/revisions\/40288"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/40204"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=40142"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=40142"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=40142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}