{"id":42726,"date":"2022-09-16T08:00:14","date_gmt":"2022-09-16T00:00:14","guid":{"rendered":"\/\/www.gsbet888.com\/?p=42726"},"modified":"2022-09-13T17:17:49","modified_gmt":"2022-09-13T09:17:49","slug":"%e5%8f%af%e6%80%95%e7%9a%84%e7%97%9b%e9%a3%8e%ef%bc%9a%e7%bb%86%e8%ae%ba%e5%b0%bf%e9%85%b8%e7%9a%84%e5%8a%9f%e4%b8%8e%e8%bf%87","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/2022\/09\/%e5%8f%af%e6%80%95%e7%9a%84%e7%97%9b%e9%a3%8e%ef%bc%9a%e7%bb%86%e8%ae%ba%e5%b0%bf%e9%85%b8%e7%9a%84%e5%8a%9f%e4%b8%8e%e8%bf%87.html","title":{"rendered":"\u53ef\u6015\u7684\u75db\u98ce\uff1a\u7ec6\u8bba\u5c3f\u9178\u7684\u529f\u4e0e\u8fc7"},"content":{"rendered":"<p>\u8bd1\u81eaChem-Station\u7f51\u7ad9\u65e5\u672c\u7248 \u539f\u6587\u94fe\u63a5\uff1a<a href=\"https:\/\/www.chem-station.com\/molecule\/2021\/02\/uricacid.html\">\u5c3f\u9178 Uric Acid \u301c\u75db\u98a8\u30ea\u30b9\u30af\u3068\u6297\u9178\u5316\u4f5c\u7528\u306e\u30b8\u30ec\u30f3\u30de\u301c<\/a><\/p>\n<p>\u7ffb\u8bd1\uff1a\u70b8\u9e21<\/p>\n<p>\u8bfb\u8005\u4eec\u6709\u6ce8\u610f\u8fc7\u5c3f\u9178\uff08Uric 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srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/09\/645c9da080b6f0ea0f17acc25170f95b.png 572w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/09\/645c9da080b6f0ea0f17acc25170f95b-300x136.png 300w\" sizes=\"(max-width: 572px) 100vw, 572px\" \/><\/p>\n<p><strong><em>\u56fe<\/em><\/strong><strong><em>1 <\/em><\/strong><em>\u560c\u5464\u7684\u4ee3\u8c22<\/em><\/p>\n<p>\u5c3f\u9178\u662f\u600e\u4e48\u5bfc\u81f4\u901a\u98ce\u7684\u5462\uff1f\u8fd9\u4e0e\u5c3f\u9178\u7684\u7269\u7406\u6027\u8d28\u5bc6\u4e0d\u53ef\u5206\u3002\u6700\u7ec8\u751f\u6210\u7269\u5c3f\u9178\u7684\u94a0\u76d0\u5728\u8840\u6d46\u4e2d\u7684\u6eb6\u89e3\u5ea6\u4e3a<strong>7.0 mg\/dL=<\/strong><strong>\u7ea6<\/strong><strong>400<\/strong><strong>\u03bcM<\/strong><strong>\uff0c\u8fd9\u4e00\u6eb6\u89e3\u5ea6\u6bd4\u8bb8\u591a\u836f\u54c1\u90fd\u8981\u9ad8\u3002\u6b63\u5e38\u4eba\u4f53\u5185\u7684\u5c3f\u9178\u503c\u4e3a<\/strong><strong>2~7 mg\/dL<\/strong><strong>\uff0c\u8fd1\u4e4e\u4e8e\u9971\u548c\u6d53\u5ea6\u3002\u4e00\u65e6\u4f53\u5185\u5c3f\u9178\u503c\u8d85\u8fc7\u9971\u548c\u6d53\u5ea6\uff0c\u591a\u4f59\u7684\u5c3f\u9178\u94a0\u76d0\u5927\u591a\u4f1a\u4ee5\u7ed3\u6676\u7684\u5f62\u5f0f\u6790\u51fa\u3002\u5728\u6e29\u5ea6\u8f83\u4f4e\u7684\u90e8\u4f4d\u5982\u811a\u62c7\u8dbe\u5173\u8282\u7b49\u5904\u66f4\u5bb9\u6613\u5f62\u6210\u7ed3\u6676\u3002\u8fd9\u4e5f\u5c31\u89e3\u91ca\u4e86\u4e3a\u4ec0\u4e48\u75db\u98ce\u7684\u597d\u53d1\u90e8\u4f4d\u591a\u4e3a\u811a\u62c7\u6307\u7684\u5173\u8282\u5904\u3002<\/strong><\/p>\n<p>\u8fd1\u5e74\u6765\u5c3f\u9178\u7ed3\u6676\u88ab\u5f52\u7c7b\u4e3a\u4e00\u79cdDAMPs\u00a0(damage-associated molecular patterns)\uff0c\u6e10\u6e10\u88ab\u89c6\u4e3a\u53cd\u6620\u7ec6\u80de\u5185\u538b\u529b\u7684\u4e00\u79cd\u56e0\u5b50\u3002\u9ad8\u5c3f\u9178\u8840\u75c7\u4e0d\u4ec5\u4f5c\u4e3a\u75db\u98ce\u7684\u98ce\u9669\u56e0\u5b50\uff0c\u8fd8\u4f5c\u4e3a<strong>\u9ad8\u8840\u538b<\/strong>\u548c<strong>\u52a8\u8109\u786c\u5316<\/strong>\u7b49\u591a\u79cd\u751f\u6d3b\u4e60\u60ef\u75c5\u7684\u98ce\u9669\u56e0\u5b50\u3002\u9ad8\u5c3f\u9178\u8840\u75c7\u53ef\u6015\u4e4b\u5904\u5728\u4e8e\u5c3f\u9178\u7ed3\u6676\u5728\u80be\u810f\u4e2d\u5f15\u8d77\u7684\u708e\u75c7\u53cd\u5e94\uff0c\u5373\u6240\u8c13\u7684 &#8220;\u75db\u98ce\u80be&#8221;\uff0c\u8fd9\u53ef\u80fd\u5f15\u8d77\u80be\u8870\u7aed\u4e0d\u5f97\u4e0d\u900f\u6790\u6cbb\u7597\uff0c\u4e25\u91cd\u751a\u81f3\u5bfc\u81f4\u6b7b\u4ea1\u3002<\/p>\n<p>\u4e9a\u5386\u5c71\u5927\u5927\u5e1d\uff0c\u8def\u6613\u5341\u56db\uff0c\u62ff\u7834\u4ed1\uff0c\u8fbe\u82ac\u5947\u7b49\u540d\u4eba\u90fd\u53d7\u8fc7\u75db\u98ce\u7684\u6298\u78e8\uff0c\u6240\u4ee5\u75db\u98ce\u5728\u53e4\u4ee3\u4e5f\u88ab\u79f0\u4e3a\u541b\u4e3b\u75c5\u6216\u5bcc\u8d35\u75c5\u3002\u53ea\u6709\u5230\u4e86\u8fd1\u4ee3\uff0c\u666e\u901a\u4eba\u624d\u6709\u9891\u7e41\u6444\u53d6\u5bcc\u542b\u560c\u5464\u7684\u98df\u7269\u7684\u673a\u4f1a\uff0c\u6240\u4ee5\u75db\u98ce\u7b49\u751f\u6d3b\u4e60\u60ef\u75c5\u4e00\u5f00\u59cb\u662f\u7a00\u6709\u75c5\u75c7\u3002\u54fa\u4e73\u7c7b\u52a8\u7269\u4e2d\u53ea\u6709\u4ee5\u4eba\u7c7b\u4e3a\u4ee3\u8868\u7684\u9ad8\u7b49\u7075\u957f\u7c7b\u52a8\u7269\u4ee5\u5c3f\u9178\u7684\u5f62\u5f0f\u4ee3\u8c22\u6389\u6838\u9178\u78b1\u57fa\uff0c\u5176\u4ed6\u54fa\u4e73\u7c7b\u52a8\u7269\u4f53\u5185\u6709\u80fd\u628a\u5c3f\u9178\u4ee3\u8c22\u4e3a\u66f4\u7b80\u5355\u7ed3\u6784\u7684\u7269\u8d28\u7136\u540e\u6392\u6cc4\u6389\u7684\u9176\uff08\u56fe2\uff09\uff0c\u53ef\u4ee5\u8bf4\u4eba\u7c7b\u5728\u8fdb\u5316\u8fc7\u7a0b\u4e2d\u820d\u5f03\u4e86\u5c3f\u9178\u4ee3\u8c22\u9176\u3002\u5173\u4e8e\u4e3a\u4ec0\u4e48\u820d\u5f03\u6389\u5c3f\u9178\u4ee3\u8c22\u9176\u4e00\u76f4\u4f17\u8bf4\u7eb7\u7ead\uff0c\u4e00\u5047\u8bf4\u662f\u56e0\u4e3a<strong>\u5c3f\u9178\u5177\u6709\u6297\u6c27\u5316\u4f5c\u7528<\/strong>\u3002<\/p>\n<h4>\u5c3f\u9178\u662f\u4f53\u5185\u6700\u5f3a\u7684\u6297\u6c27\u5316\u5242<\/h4>\n<p>\u5c3f\u9178\u662f\u4e00\u79cd\u975e\u5e38\u6709\u6548\u7684\u6297\u6c27\u5316\u5242\u3002\u5f53\u673a\u4f53\u5229\u7528\u6c27\u6c14O<sub>2<\/sub>\u83b7\u53d6\u80fd\u91cf\u65f6\uff0c\u673a\u4f53\u4e0d\u65ad\u53d7\u5230<strong>\u6d3b\u6027\u6c27\uff08<\/strong><strong>ROS<\/strong><strong>\uff09<\/strong>\u7684\u6c27\u5316\u538b\u529b\u7684\u5a01\u80c1\u3002\u5728\u4f53\u5185\u4ea7\u751f\u7684ROS\u662f\u7a7a\u6c14\u4e2d\u7684<strong>\u4e09\u7ebf\u6001\u6c27<\/strong><strong>\u00a0<sup>3<\/sup>O<\/strong><strong>2<\/strong><strong>\u7ecf\u8fc7\u9636\u6bb5\u6027\u7684\u4e00\u7535\u5b50\u8fd8\u539f\u5f97\u5230\u7684\uff0c<\/strong><strong>ROS<\/strong><strong>\u6709\uff1a<\/strong>\u8d85\u6c27\u9634\u79bb\u5b50\u81ea\u7531\u57fa\uff08O<sup>2-<\/sup>\u2022\uff09\u3001\u8fc7\u6c27\u5316\u6c22\uff08H<sub>2<\/sub>O<sub>2<\/sub>\uff09\u3001\u7f9f\u57fa\u81ea\u7531\u57fa (\u2022OH)\u3001\u80fd\u91cf\u6bd4<strong><sup>3<\/sup><\/strong><strong>O<\/strong><strong>2<\/strong><strong>\u8fd8\u9ad8\u7684<\/strong>\u5206\u5b50\u6001\u6c27\u7684\u5355\u7ebf\u6001\u6c27<sup>1<\/sup>O<sub>2<\/sub>\uff0c\u8fd8\u6709\u8d85\u6c27\u5316\u7269\u548c\u4e00\u6c27\u5316\u6c2e(NO)\u00a0\u7684\u53cd\u5e94\u4ea7\u7269\u8fc7\u6c27\u5316\u4e9a\u785d\u9178\u76d0(ONOO<sup>&#8211;<\/sup>)\u3002\u5c3f\u9178\u80fd\u6e05\u9664\u7279\u522b\u6d3b\u6cfc\u7684\u6d3b\u6027\u6c27\uff08ROS\uff09\uff0c\u5982\u7f9f\u57fa\u81ea\u7531\u57fa\u3001\u5355\u7ebf\u6001\u6c27\u548c\u8fc7\u6c27\u5316\u4e9a\u785d\u9178\u76d0\u3002\u8fd8\u6709\u7814\u7a76\u8868\u660e\u5c3f\u9178\u8fd8\u80fd\u6709\u6548\u5730\u6e05\u9664\u6d3b\u6027\u6c27\uff08ROS\uff09\u4ea7\u751f\u7684\u8102\u8d28\u81ea\u7531\u57fa\u548c\u8102\u8d28\u8fc7\u6c27\u81ea\u7531\u57fa\u3002<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-42725 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/09\/image005.jpg\" alt=\"\" width=\"1171\" height=\"218\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/09\/image005.jpg 1171w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/09\/image005-300x56.jpg 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/09\/image005-680x127.jpg 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/09\/image005-768x143.jpg 768w\" sizes=\"(max-width: 1171px) 100vw, 1171px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><em>\u56fe<\/em><em>2 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Acid\uff09\u503c\u5417?\u6211\u4eec\u77e5\u9053\uff1a\u5f53\u4eba\u4f53\u6444\u5165\u8fc7\u91cf\u7684\u560c\u5464\uff08\u5728\u5564\u9152\u548c\u8089\u7c7b\u4e2d\u542b\u91cf\u4e30\u5bcc\uff09\u4f1a\u5f15\u8d77\u9ad8\u5c3f\u9178\u8840\u75c7\uff0c\u8fd9\u5c31\u662f\u53ef\u6015\u7684\u75db\u98ce\u7684\u8bf1\u56e0\u3002\u56e0\u4e3a\u75db\u98ce\u53d1\u4f5c\u65f6\u7684\u4e07\u5206\u75db\u82e6\uff0c\u6240\u4ee5\u75db\u98ce\u662f\u4eba\u4eec\u6700\u4e0d\u60f3\u60a3\u4e0a\u7684\u75be\u75c5\u4e4b\u4e00\u3002\u4f46\u4e0d\u53ef\u5426\u8ba4\u7684\u662f\u5c3f\u9178\u5b9e\u9645\u4e0a\u7b97\u662f\u5bf9\u4eba\u4f53\u6709\u76ca\u5904\u7684\u5316\u5408\u7269\u3002\u672c\u7bc7\u8bb0\u4e8b\u5c06\u4f1a\u8bba\u8bba\u5c3f\u9178\u7684\u201c\u529f\u201d\u4e0e\u201c\u8fc7\u201d\u3002 \u4f34\u968f\u4e00\u751f\u7684\u53ef\u6015\u7684\u901a\u98ce \u5c3f\u9178\uff08uric 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patterns)\uff0c\u6e10\u6e10\u88ab\u89c6\u4e3a\u53cd\u6620\u7ec6\u80de\u5185\u538b\u529b\u7684\u4e00\u79cd\u56e0\u5b50\u3002\u9ad8\u5c3f\u9178\u8840\u75c7\u4e0d\u4ec5\u4f5c\u4e3a\u75db\u98ce\u7684\u98ce\u9669\u56e0\u5b50\uff0c\u8fd8\u4f5c\u4e3a\u9ad8\u8840\u538b\u548c\u52a8\u8109\u786c\u5316\u7b49\u591a\u79cd\u751f\u6d3b\u4e60\u60ef\u75c5\u7684\u98ce\u9669\u56e0\u5b50\u3002\u9ad8\u5c3f\u9178\u8840\u75c7\u53ef\u6015\u4e4b\u5904\u5728\u4e8e\u5c3f\u9178\u7ed3\u6676\u5728\u80be\u810f\u4e2d\u5f15\u8d77\u7684\u708e\u75c7\u53cd\u5e94\uff0c\u5373\u6240\u8c13\u7684 &#8220;\u75db\u98ce\u80be&#8221;\uff0c\u8fd9\u53ef\u80fd\u5f15\u8d77\u80be\u8870\u7aed\u4e0d\u5f97\u4e0d\u900f\u6790\u6cbb\u7597\uff0c\u4e25\u91cd\u751a\u81f3\u5bfc\u81f4\u6b7b\u4ea1\u3002 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