{"id":43429,"date":"2022-10-30T08:00:36","date_gmt":"2022-10-30T00:00:36","guid":{"rendered":"\/\/www.gsbet888.com\/?p=43429"},"modified":"2022-10-28T19:13:25","modified_gmt":"2022-10-28T11:13:25","slug":"acs-catal-%ef%bc%9a%e7%83%af%e5%9f%ba%e5%8c%96%e5%90%88%e7%89%a9%e7%9a%84%e4%bd%8d%e7%82%b9%e9%80%89%e6%8b%a9%e6%80%a7%e6%b0%a2%e6%b0%9f%e7%83%b7%e5%9f%ba%e5%8c%96%e5%8f%8d%e5%ba%94%e6%96%b9%e6%b3%95","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/recentpaper\/2022\/10\/acs-catal-%ef%bc%9a%e7%83%af%e5%9f%ba%e5%8c%96%e5%90%88%e7%89%a9%e7%9a%84%e4%bd%8d%e7%82%b9%e9%80%89%e6%8b%a9%e6%80%a7%e6%b0%a2%e6%b0%9f%e7%83%b7%e5%9f%ba%e5%8c%96%e5%8f%8d%e5%ba%94%e6%96%b9%e6%b3%95.html","title":{"rendered":"ACS Catal.\uff1a\u70ef\u57fa\u5316\u5408\u7269\u7684\u4f4d\u70b9\u9009\u62e9\u6027\u6c22\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\u7814\u7a76"},"content":{"rendered":"<p>\u672c\u6587\u4f5c\u8005\uff1a\u6749\u6749<\/p>\n<h4>\u5bfc\u8bfb\uff1a<\/h4>\n<p>\u8fd1\u65e5\uff0c\u897f\u73ed\u7259ICIQ\u7684R. Martin\u8bfe\u9898\u7ec4\u5728<em><i>ACS Catalysis<\/i><\/em>\u4e2d\u53d1\u8868\u8bba\u6587\uff0c\u62a5\u9053\u4e00\u79cd\u5168\u65b0\u7684\u91c7\u7528\u954d\u50ac\u5316\u5242\u4fc3\u8fdb\u7684\u901a\u8fc7\u7aef\u70ef\u57fa\u6216\u5185\u70ef\u57fa\u5316\u5408\u7269\u53c2\u4e0e\u7684\u4f4d\u70b9\u9009\u62e9\u6027 (anti-Markovnikov)\u6c22\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u5355\u6c1f\u70f7\u57fa\u5316\u5408\u7269\u7684\u6784\u5efa\u3002<\/p>\n<blockquote><p>Ni-Catalyzed Site-Selective Hydrofluoroalkylation of Terminal and\u00a0Internal Olefins<\/p>\n<p>Wen-Jun Yue, Ruben Martin. <em>ACS Catal.<\/em>\u00a0<strong>2022<\/strong>,\u00a0ASAP. doi: <a href=\"https:\/\/doi.org\/10.1021\/acscatal.2c04412\"><u>10.1021\/acscatal.2c04412<\/u><\/a><u>.<\/u><\/p><\/blockquote>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-43431 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/bed15923c0c1704457366c276a1f0c19.png\" alt=\"\" width=\"830\" height=\"219\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/bed15923c0c1704457366c276a1f0c19.png 830w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/bed15923c0c1704457366c276a1f0c19-300x79.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/bed15923c0c1704457366c276a1f0c19-680x179.png 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/bed15923c0c1704457366c276a1f0c19-768x203.png 768w\" sizes=\"(max-width: 830px) 100vw, 830px\" \/><\/p>\n<h4>\u6b63\u6587\uff1a<\/h4>\n<p>\u76ee\u524d\uff0c\u542b\u6c1f\u6709\u673a\u5206\u5b50\u5df2\u7ecf\u5e7f\u6cdb\u5e94\u7528\u4e8e\u533b\u836f\u5316\u5b66\u9886\u57df\u7684\u76f8\u5173\u7814\u7a76\u3002\u7136\u800c\uff0c\u5bf9\u4e8e\u50ac\u5316\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\u7684\u76f8\u5173\u7814\u7a76\uff0c\u4ecd\u9762\u4e34\u8f83\u5927\u7684\u6311\u6218<sup>[1]-[4]<\/sup>\u3002\u8fd9\u91cc\uff0c\u53d7\u5230\u8fd1\u5e74\u6765\u5bf9\u4e8e\u901a\u8fc7\u954d\u50ac\u5316\u5242\u53c2\u4e0e\u7684\u6709\u673a\u5408\u6210\u8f6c\u5316\u65b9\u6cd5\u5b66<sup>[5]<\/sup>\u4ee5\u53ca\u70ef\u57fa\u5316\u5408\u7269\u5b98\u80fd\u56e2\u5316<sup>[6]<\/sup>\u53cd\u5e94\u65b9\u6cd5\u5b66\u76f8\u5173\u7814\u7a76\u62a5\u9053\u7684\u542f\u53d1\uff0c\u897f\u73ed\u7259ICIQ\u7684R. Martin\u56e2\u961f\u6210\u529f\u8bbe\u8ba1\u51fa\u4e00\u79cd\u5168\u65b0\u7684\u91c7\u7528\u954d\u50ac\u5316\u5242\u4fc3\u8fdb\u7684\u901a\u8fc7\u7aef\u70ef\u57fa\u6216\u5185\u70ef\u57fa\u5316\u5408\u7269\u53c2\u4e0e\u7684anti-Markovnikov\u6c22\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66 (Scheme 1)\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-43432 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/2012fe7f9d91d0b4d7e0b63f25553deb.png\" alt=\"\" width=\"772\" height=\"715\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/2012fe7f9d91d0b4d7e0b63f25553deb.png 772w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/2012fe7f9d91d0b4d7e0b63f25553deb-300x278.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/2012fe7f9d91d0b4d7e0b63f25553deb-680x630.png 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/2012fe7f9d91d0b4d7e0b63f25553deb-768x711.png 768w\" sizes=\"(max-width: 772px) 100vw, 772px\" \/><\/p>\n<p>\u9996\u5148\uff0c\u4f5c\u8005\u91c7\u7528\u5355\u6c1f\u5316\u5408\u7269<strong>1a<\/strong>\u4e0e\u70ef\u57fa\u884d\u751f\u7269<strong>2a<\/strong>\u4f5c\u4e3a\u6a21\u578b\u5e95\u7269\uff0c\u8fdb\u884c\u76f8\u5173\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316\u7b5b\u9009 (Table 1)\u3002\u8fdb\u800c\u786e\u5b9a\u6700\u4f73\u7684\u53cd\u5e94\u6761\u4ef6\u4e3a\uff1a\u91c7\u7528NiBr<sub>2<\/sub>\u2022glyme\u4f5c\u4e3a\u50ac\u5316\u5242\uff0c<strong>L1<\/strong>\u4f5c\u4e3a\u914d\u4f53\uff0c(EtO)<sub>2<\/sub>MeSiH\u4f5c\u4e3a\u7845\u70f7\u6e90 (silanes source)\uff0cNa<sub>2<\/sub>HPO<sub>4<\/sub>\u4f5c\u4e3a\u6dfb\u52a0\u5242\uff0cDMSO\u4f5c\u4e3a\u53cd\u5e94\u6eb6\u5242\uff0c\u53cd\u5e94\u6e29\u5ea6\u4e3a40\u00a0<sup>o<\/sup>C\uff0c\u6700\u7ec8\u83b7\u5f9789%\u6536\u7387\u7684\u4ea7\u7269<strong>3a<\/strong>\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-43433 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/47307fe62c975eadca4de5bdafc56692.png\" alt=\"\" width=\"772\" height=\"870\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/47307fe62c975eadca4de5bdafc56692.png 772w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/47307fe62c975eadca4de5bdafc56692-266x300.png 266w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/47307fe62c975eadca4de5bdafc56692-680x766.png 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/47307fe62c975eadca4de5bdafc56692-768x865.png 768w\" sizes=\"(max-width: 772px) 100vw, 772px\" \/><\/p>\n<p>\u5728\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u4e0b\uff0c\u4f5c\u8005\u5206\u522b\u5bf9\u4e00\u7cfb\u5217<em>\u03b1<\/em>-\u70ef\u57fa\u5e95\u7269 (Table 2)\u4ee5\u53ca\u5185\u70ef\u57fa\u5e95\u7269 (Table 3)\u7684\u5e94\u7528\u8303\u56f4\u8fdb\u884c\u6df1\u5165\u7814\u7a76\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-43434 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/c2bee16d31df50a082800a07918c0188.png\" alt=\"\" width=\"1108\" height=\"1250\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/c2bee16d31df50a082800a07918c0188.png 1108w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/c2bee16d31df50a082800a07918c0188-266x300.png 266w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/c2bee16d31df50a082800a07918c0188-680x767.png 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/c2bee16d31df50a082800a07918c0188-768x866.png 768w\" sizes=\"(max-width: 1108px) 100vw, 1108px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-43435 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/15f822af2c52a61e01eb2cf321e5a8d2.png\" alt=\"\" width=\"1106\" height=\"808\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/15f822af2c52a61e01eb2cf321e5a8d2.png 1106w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/15f822af2c52a61e01eb2cf321e5a8d2-300x219.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/15f822af2c52a61e01eb2cf321e5a8d2-680x497.png 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/15f822af2c52a61e01eb2cf321e5a8d2-768x561.png 768w\" sizes=\"(max-width: 1106px) 100vw, 1106px\" \/><\/p>\n<p>\u4e4b\u540e\uff0c\u8be5\u5c0f\u7ec4\u901a\u8fc7\u5982\u4e0b\u7684\u4e00\u7cfb\u5217\u7814\u7a76\u8fdb\u4e00\u6b65\u8868\u660e\uff0c\u8fd9\u4e00\u5168\u65b0\u7684\u5355\u6c1f\u70f7\u57fa\u5316\u7b56\u7565\u5177\u6709\u6f5c\u5728\u7684\u5408\u6210\u5e94\u7528\u4ef7\u503c\u00a0(Scheme 2 and Scheme 3)\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-43436 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/8705a65bd86f81ab2f5d3a513dca30f2.png\" alt=\"\" width=\"780\" height=\"1586\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/8705a65bd86f81ab2f5d3a513dca30f2.png 780w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/8705a65bd86f81ab2f5d3a513dca30f2-148x300.png 148w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/8705a65bd86f81ab2f5d3a513dca30f2-504x1024.png 504w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/8705a65bd86f81ab2f5d3a513dca30f2-768x1562.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/8705a65bd86f81ab2f5d3a513dca30f2-755x1536.png 755w\" sizes=\"(max-width: 780px) 100vw, 780px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-43437 size-full\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/f14581c94ce6034f3ac4adae57217d95.png\" alt=\"\" width=\"792\" height=\"922\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/f14581c94ce6034f3ac4adae57217d95.png 792w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/f14581c94ce6034f3ac4adae57217d95-258x300.png 258w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/f14581c94ce6034f3ac4adae57217d95-680x792.png 680w, https:\/\/assets.www.gsbet888.com\/uploads\/2022\/10\/f14581c94ce6034f3ac4adae57217d95-768x894.png 768w\" sizes=\"(max-width: 792px) 100vw, 792px\" \/><\/p>\n<h4>\u603b\u7ed3\uff1a<\/h4>\n<p>\u897f\u73ed\u7259ICIQ\u7684R. Martin\u56e2\u961f\u6210\u529f\u8bbe\u8ba1\u51fa\u4e00\u79cd\u5168\u65b0\u7684\u91c7\u7528\u954d\u50ac\u5316\u5242\u4fc3\u8fdb\u7684\u901a\u8fc7\u7aef\u70ef\u57fa\u6216\u5185\u70ef\u57fa\u5316\u5408\u7269\u53c2\u4e0e\u7684anti-Markovnikov\u6c22\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u5355\u6c1f\u70f7\u57fa\u5316\u5408\u7269\u7684\u6784\u5efa\u3002\u8fd9\u4e00\u5168\u65b0\u7684\u6c22\u6c1f\u70f7\u57fa\u5316\u7b56\u7565\u5177\u6709\u6e29\u548c\u7684\u53cd\u5e94\u6761\u4ef6\u3001\u5e7f\u6cdb\u7684\u5e95\u7269\u5e94\u7528\u8303\u56f4\u4ee5\u53ca\u4f18\u826f\u7684\u4f4d\u70b9\u9009\u62e9\u6027\u7b49\u4f18\u52bf\u3002<\/p>\n<h4><strong>\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/h4>\n<ul>\n<li>[1]\u00a0T. W.\u00a0Butcher, W. M.\u00a0Amberg, J. F. Hartwig, <em>Angew. Chem., Int. Ed. <\/em><strong>2022<\/strong>, <em>61<\/em>, e202112251.\u00a0doi:<a href=\"https:\/\/doi.org\/10.1002\/anie.202112251\"><u>10.1002\/anie.202112251<\/u><\/a><u>.<\/u><\/li>\n<li>[2] X.\u00a0Jiang, M. Gandelman, <em>J. Am.<\/em><em>\u00a0<\/em><em>Chem. Soc.<\/em>\u00a0<strong>2015<\/strong>, <em>137<\/em>, 2542.\u00a0doi:<a href=\"https:\/\/doi.org\/10.1021\/jacs.5b00473\"><u>10.1021\/jacs.5b00473<\/u><\/a><u>.<\/u><\/li>\n<li>[3]\u00a0J.\u00a0Sheng, H. Ni, S. Ni, Y. He, R. Cui, G. Liao, K. Bian, B. Wu, X. Wang, <em>Angew.<\/em><em>\u00a0<\/em><em>Chem., Int. Ed.<\/em>\u00a0<strong>2021<\/strong>, <em>60<\/em>, 15020.\u00a0doi:<a href=\"https:\/\/doi.org\/10.1002\/anie.202102481\"><u>10.1002\/anie.202102481<\/u><\/a><u>.<\/u><\/li>\n<li>[4] H.\u00a0Wang, C. Liu, Z. Song, M.\u00a0Yuan, Y. A. Ho, O. Gutierrez, M. J. Koh, <em><i>ACS Catal. <\/i><\/em><strong>2020<\/strong>, <em><i>10<\/i><\/em>, 4451.\u00a0doi:<a href=\"https:\/\/doi.org\/10.1021\/acscatal.0c00789\"><u>10.1021\/acscatal.0c00789<\/u><\/a><u>.<\/u><\/li>\n<li>[5]\u00a0W. J.\u00a0Yue, C. S. Day, R. Martin, <em><i>J. Am. Chem. Soc. <\/i><\/em><strong>2021<\/strong>, <em><i>143<\/i><\/em>, 6395.\u00a0doi:<a href=\"https:\/\/doi.org\/10.1021\/jacs.1c03126\"><u>10.1021\/jacs.1c03126<\/u><\/a><u>.<\/u><\/li>\n<li>[6] T.\u00a0Jankins, R. Martin-Montero, P. Cooper, R. Martin, K. Engle, <em>J. Am. Chem. Soc. <\/em><strong>2021<\/strong>, <em>143<\/em>, 14981.\u00a0doi:<a href=\"https:\/\/doi.org\/10.1021\/jacs.1c07162\"><u>10.1021\/jacs.1c07162<\/u><\/a><u>.<\/u><\/li>\n<\/ul>\n<p>\u672c\u6587\u7248\u6743\u5c5e\u4e8e\u00a0Chem-Station\u5316\u5b66\u7a7a\u95f4\uff0c \u6b22\u8fce\u70b9\u51fb\u6309\u94ae\u5206\u4eab\uff0c\u672a\u7ecf\u8bb8\u53ef\uff0c\u8c22\u7edd\u8f6c\u8f7d<\/p>\n","protected":false},"excerpt":{"rendered":"\u672c\u6587\u4f5c\u8005\uff1a\u6749\u6749 \u5bfc\u8bfb\uff1a \u8fd1\u65e5\uff0c\u897f\u73ed\u7259ICIQ\u7684R. Martin\u8bfe\u9898\u7ec4\u5728ACS Catalysis\u4e2d\u53d1\u8868\u8bba\u6587\uff0c\u62a5\u9053\u4e00\u79cd\u5168\u65b0\u7684\u91c7\u7528\u954d\u50ac\u5316\u5242\u4fc3\u8fdb\u7684\u901a\u8fc7\u7aef\u70ef\u57fa\u6216\u5185\u70ef\u57fa\u5316\u5408\u7269\u53c2\u4e0e\u7684\u4f4d\u70b9\u9009\u62e9\u6027 (anti-Markovnikov)\u6c22\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u5355\u6c1f\u70f7\u57fa\u5316\u5408\u7269\u7684\u6784\u5efa\u3002 Ni-Catalyzed Site-Selective Hydrofluoroalkylation of Terminal and\u00a0Internal Olefins Wen-Jun Yue, Ruben Martin. ACS Catal.\u00a02022,\u00a0ASAP. doi: 10.1021\/acscatal.2c04412. \u6b63\u6587\uff1a \u76ee\u524d\uff0c\u542b\u6c1f\u6709\u673a\u5206\u5b50\u5df2\u7ecf\u5e7f\u6cdb\u5e94\u7528\u4e8e\u533b\u836f\u5316\u5b66\u9886\u57df\u7684\u76f8\u5173\u7814\u7a76\u3002\u7136\u800c\uff0c\u5bf9\u4e8e\u50ac\u5316\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\u7684\u76f8\u5173\u7814\u7a76\uff0c\u4ecd\u9762\u4e34\u8f83\u5927\u7684\u6311\u6218[1]-[4]\u3002\u8fd9\u91cc\uff0c\u53d7\u5230\u8fd1\u5e74\u6765\u5bf9\u4e8e\u901a\u8fc7\u954d\u50ac\u5316\u5242\u53c2\u4e0e\u7684\u6709\u673a\u5408\u6210\u8f6c\u5316\u65b9\u6cd5\u5b66[5]\u4ee5\u53ca\u70ef\u57fa\u5316\u5408\u7269\u5b98\u80fd\u56e2\u5316[6]\u53cd\u5e94\u65b9\u6cd5\u5b66\u76f8\u5173\u7814\u7a76\u62a5\u9053\u7684\u542f\u53d1\uff0c\u897f\u73ed\u7259ICIQ\u7684R. Martin\u56e2\u961f\u6210\u529f\u8bbe\u8ba1\u51fa\u4e00\u79cd\u5168\u65b0\u7684\u91c7\u7528\u954d\u50ac\u5316\u5242\u4fc3\u8fdb\u7684\u901a\u8fc7\u7aef\u70ef\u57fa\u6216\u5185\u70ef\u57fa\u5316\u5408\u7269\u53c2\u4e0e\u7684anti-Markovnikov\u6c22\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66 (Scheme 1)\u3002 \u9996\u5148\uff0c\u4f5c\u8005\u91c7\u7528\u5355\u6c1f\u5316\u5408\u72691a\u4e0e\u70ef\u57fa\u884d\u751f\u72692a\u4f5c\u4e3a\u6a21\u578b\u5e95\u7269\uff0c\u8fdb\u884c\u76f8\u5173\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316\u7b5b\u9009 (Table 1)\u3002\u8fdb\u800c\u786e\u5b9a\u6700\u4f73\u7684\u53cd\u5e94\u6761\u4ef6\u4e3a\uff1a\u91c7\u7528NiBr2\u2022glyme\u4f5c\u4e3a\u50ac\u5316\u5242\uff0cL1\u4f5c\u4e3a\u914d\u4f53\uff0c(EtO)2MeSiH\u4f5c\u4e3a\u7845\u70f7\u6e90 (silanes source)\uff0cNa2HPO4\u4f5c\u4e3a\u6dfb\u52a0\u5242\uff0cDMSO\u4f5c\u4e3a\u53cd\u5e94\u6eb6\u5242\uff0c\u53cd\u5e94\u6e29\u5ea6\u4e3a40\u00a0oC\uff0c\u6700\u7ec8\u83b7\u5f9789%\u6536\u7387\u7684\u4ea7\u72693a\u3002 \u5728\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u4e0b\uff0c\u4f5c\u8005\u5206\u522b\u5bf9\u4e00\u7cfb\u5217\u03b1-\u70ef\u57fa\u5e95\u7269 (Table 2)\u4ee5\u53ca\u5185\u70ef\u57fa\u5e95\u7269 (Table 3)\u7684\u5e94\u7528\u8303\u56f4\u8fdb\u884c\u6df1\u5165\u7814\u7a76\u3002 \u4e4b\u540e\uff0c\u8be5\u5c0f\u7ec4\u901a\u8fc7\u5982\u4e0b\u7684\u4e00\u7cfb\u5217\u7814\u7a76\u8fdb\u4e00\u6b65\u8868\u660e\uff0c\u8fd9\u4e00\u5168\u65b0\u7684\u5355\u6c1f\u70f7\u57fa\u5316\u7b56\u7565\u5177\u6709\u6f5c\u5728\u7684\u5408\u6210\u5e94\u7528\u4ef7\u503c\u00a0(Scheme 2 and Scheme 3)\u3002 \u603b\u7ed3\uff1a \u897f\u73ed\u7259ICIQ\u7684R. Martin\u56e2\u961f\u6210\u529f\u8bbe\u8ba1\u51fa\u4e00\u79cd\u5168\u65b0\u7684\u91c7\u7528\u954d\u50ac\u5316\u5242\u4fc3\u8fdb\u7684\u901a\u8fc7\u7aef\u70ef\u57fa\u6216\u5185\u70ef\u57fa\u5316\u5408\u7269\u53c2\u4e0e\u7684anti-Markovnikov\u6c22\u6c1f\u70f7\u57fa\u5316\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u5355\u6c1f\u70f7\u57fa\u5316\u5408\u7269\u7684\u6784\u5efa\u3002\u8fd9\u4e00\u5168\u65b0\u7684\u6c22\u6c1f\u70f7\u57fa\u5316\u7b56\u7565\u5177\u6709\u6e29\u548c\u7684\u53cd\u5e94\u6761\u4ef6\u3001\u5e7f\u6cdb\u7684\u5e95\u7269\u5e94\u7528\u8303\u56f4\u4ee5\u53ca\u4f18\u826f\u7684\u4f4d\u70b9\u9009\u62e9\u6027\u7b49\u4f18\u52bf\u3002 \u53c2\u8003\u6587\u732e\uff1a [1]\u00a0T. W.\u00a0Butcher, W. M.\u00a0Amberg, J. F. Hartwig, Angew. Chem., Int. Ed. 2022, 61, e202112251.\u00a0doi:10.1002\/anie.202112251. [2] X.\u00a0Jiang, M. Gandelman, J. Am.\u00a0Chem. Soc.\u00a02015, 137, 2542.\u00a0doi:10.1021\/jacs.5b00473. [3]\u00a0J.\u00a0Sheng, H. Ni, S. Ni, Y. He, R. Cui, G. Liao, K. Bian, B. Wu, X. Wang, Angew.\u00a0Chem., Int. Ed.\u00a02021, 60, 15020.\u00a0doi:10.1002\/anie.202102481. [4] H.\u00a0Wang, C. Liu, Z. Song, M.\u00a0Yuan, Y. A. Ho, O. Gutierrez, M. J. Koh, ACS Catal. 2020, 10, 4451.\u00a0doi:10.1021\/acscatal.0c00789. 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