{"id":50394,"date":"2024-07-25T08:00:27","date_gmt":"2024-07-25T00:00:27","guid":{"rendered":"\/\/www.gsbet888.com\/?p=50394"},"modified":"2024-07-24T18:33:46","modified_gmt":"2024-07-24T10:33:46","slug":"nat-commun-%ef%bc%9a%e6%97%a0%e9%87%91%e5%b1%9e%e5%82%ac%e5%8c%96%e5%ae%9e%e7%8e%b0%e5%bc%a0%e5%8a%9bc-c-%cf%83-%e9%94%ae%e7%9a%84%e6%9e%81%e6%80%a7%e5%8f%8d%e8%bd%ac%e5%8f%8d%e5%ba%94","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/recentpaper\/2024\/07\/nat-commun-%ef%bc%9a%e6%97%a0%e9%87%91%e5%b1%9e%e5%82%ac%e5%8c%96%e5%ae%9e%e7%8e%b0%e5%bc%a0%e5%8a%9bc-c-%cf%83-%e9%94%ae%e7%9a%84%e6%9e%81%e6%80%a7%e5%8f%8d%e8%bd%ac%e5%8f%8d%e5%ba%94.html","title":{"rendered":"Nat. Commun.\uff1a\u65e0\u91d1\u5c5e\u50ac\u5316\u5b9e\u73b0\u5f20\u529bC\u2013C \u03c3-\u952e\u7684\u6781\u6027\u53cd\u8f6c\u53cd\u5e94"},"content":{"rendered":"

\u4f5c\u8005\uff1a\u6749\u6749<\/p>\n

\u5bfc\u8bfb\uff1a<\/h4>\n

\u8fd1\u671f\uff0c\u6cb3\u5357\u5e08\u8303\u5927\u5b66\u7684\u5e38\u4fca\u6807\u4e0e\u767d\u5927\u660c\u7b49\u4eba\u5728Nat. Commun.<\/em>\u4e2d\u53d1\u8868\u8bba\u6587\uff0c\u62a5\u9053\u4e00\u79cd\u5168\u65b0\u7684\u65e0\u91d1\u5c5e\u50ac\u5316bicyclo[1.1.0]butanes (BCBs)\u4e0e\u7f3a\u7535\u5b50\u70ef\u70c3\u7684\u6781\u6027\u53cd\u8f6cAlder-ene\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u5b98\u80fd\u56e2\u5316\u7684\u73af\u4e01\u70ef\u4e0e\u5171\u8f6d\u4e8c\u70ef\u5206\u5b50\u7684\u6784\u5efa\u3002<\/p>\n

Umpolung reactivity of strained C\u2013C \u03c3<\/em>-bonds without transition-metal catalysis<\/p>\n

D. Bai, X. Guo, X. Wang, W. Xu, R. Cheng, D. Wei, Y. Lan, J. Chang, Nat. Commun.<\/em> 2024<\/strong>, 15<\/em>, 2833. doi: 10.1038\/s41467-024-47169-9<\/a>.<\/u><\/p><\/blockquote>\n

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\u6b63\u6587\uff1a<\/h4>\n

\u524d\u671f\uff0c\u8bf8\u591a\u7814\u7a76\u56e2\u961f\u5df2\u7ecf\u6210\u529f\u8bbe\u8ba1\u51fa\u591a\u79cd\u5229\u7528bicyclo[1.1.0]butane (BCBs)\u6784\u5efa\u5b98\u80fd\u56e2\u5316\u73af\u4e01\u70f7\u5206\u5b50\u7684\u5408\u6210\u8f6c\u5316\u7b56\u7565[1]<\/sup>\u3002\u7136\u800c\uff0cBCBs\u53c2\u4e0e\u7684\u6781\u6027\u53cd\u8f6c\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u76ee\u524d\u5374\u8f83\u5c11\u6709\u76f8\u5173\u7684\u7814\u7a76\u62a5\u9053(Fig. 1A) [2]<\/sup>\u3002\u53d7\u5230BCBs\u4e2d\u6781\u5316C-C \u03c3<\/em>-\u952e\u4e0e\u6d3b\u5316\u70ef\u70c3\u7684\u52a0\u6210\u53cd\u5e94\u65b9\u6cd5\u5b66(Fig. 1B) [3]<\/sup>\u76f8\u5173\u7814\u7a76\u62a5\u9053\u7684\u542f\u53d1\uff0c\u8fd9\u91cc\uff0c\u6cb3\u5357\u5e08\u8303\u5927\u5b66\u7684\u5e38\u4fca\u6807\u4e0e\u767d\u5927\u660c\u7b49\u4eba\u62a5\u9053\u4e00\u79cd\u5168\u65b0\u7684\u65e0\u91d1\u5c5e\u50ac\u5316bicyclo[1.1.0]butanes (BCBs)\u4e0e\u7f3a\u7535\u5b50\u70ef\u70c3\u7684\u6781\u6027\u53cd\u8f6cAlder-ene\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u5b98\u80fd\u56e2\u5316\u7684\u73af\u4e01\u70ef\u4e0e\u5171\u8f6d\u4e8c\u70ef\u5206\u5b50\u7684\u6784\u5efa (Fig. 1C)\u3002<\/p>\n

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\u9996\u5148\uff0c\u4f5c\u8005\u91c7\u7528bicyclo[1.1.0]butane (BCB) 1a<\/strong>\u4e0e\u70ef\u70c3\u884d\u751f\u72692a<\/strong>\u4f5c\u4e3a\u6a21\u578b\u5e95\u7269\uff0c\u8fdb\u884c\u76f8\u5173\u53cd\u5e94\u6761\u4ef6\u7684\u4f18\u5316\u7b5b\u9009 (Fig. 2)\u3002\u8fdb\u800c\u786e\u5b9a\u6700\u4f73\u7684\u53cd\u5e94\u6761\u4ef6\u4e3a\uff1a\u91c7\u7528Na2<\/sub>SO4<\/sub>\u4f5c\u4e3a\u6dfb\u52a0\u5242\uff0c\u5728DMSO\u53cd\u5e94\u6eb6\u5242\u4e2d\uff0c\u53cd\u5e94\u6e29\u5ea6\u4e3a80 o<\/sup>C\uff0c\u6700\u7ec8\u83b7\u5f9791%\u6536\u7387\u7684\u4ea7\u72693a<\/strong>\u3002<\/p>\n

\"\"<\/p>\n

\u5728\u4e0a\u8ff0\u7684\u6700\u4f73\u53cd\u5e94\u6761\u4ef6\u4e0b\uff0c\u4f5c\u8005\u5206\u522b\u5bf9\u4e00\u7cfb\u5217\u5355\u53d6\u4ee3BCBs\u5e95\u7269 (Fig. 3)\u4ee5\u53ca1,2-\u4e8c\u53d6\u4ee3\u70ef\u70c3\u5e95\u7269 (Fig. 4)\u7684\u5e94\u7528\u8303\u56f4\u8fdb\u884c\u6df1\u5165\u7814\u7a76\u3002<\/p>\n

\"\" \"\" \"\" \"\"<\/p>\n

\u540c\u65f6\uff0c\u4f5c\u8005\u8fd8\u5bf9BCBs\u4e2d\u03b2<\/em>-\u4f4d\u7684\u53d6\u4ee3\u57fa\u5bf9\u6781\u6027\u53cd\u8f6c\u53cd\u5e94\u7684\u5f71\u54cd\u8fdb\u884c\u4e86\u7814\u7a76(Fig. 5)\u3002<\/p>\n

\"\" \"\"<\/p>\n

\u4e4b\u540e\uff0c\u8be5\u5c0f\u7ec4\u901a\u8fc7\u5982\u4e0b\u7684\u4e00\u7cfb\u5217\u7814\u7a76\u8fdb\u4e00\u6b65\u8868\u660e\uff0c\u8fd9\u4e00\u5168\u65b0\u7684\u6781\u6027\u53cd\u8f6cAlder-ene\u7b56\u7565\u5177\u6709\u6f5c\u5728\u7684\u5408\u6210\u5e94\u7528\u4ef7\u503c (Fig. 6)\u3002<\/p>\n

\"\"<\/p>\n

\u63a5\u4e0b\u6765\uff0c\u4f5c\u8005\u5bf9\u4e0a\u8ff0\u6781\u6027\u53cd\u8f6cAlder-ene\u8fc7\u7a0b\u7684\u53cd\u5e94\u673a\u7406\u8fdb\u884c\u8fdb\u4e00\u6b65\u7814\u7a76 \u00a0(Fig. 7)\u3002<\/p>\n

\"\" \"\"<\/p>\n

\u6b64\u5916\uff0c\u4f5c\u8005\u8fd8\u5bf9\u53cd\u5e94\u7684\u8fc7\u7a0b\u8fdb\u884c\u4e86\u76f8\u5173\u7684\u7406\u8bba\u8ba1\u7b97\u7814\u7a76 (Fig. 8)\u3002<\/p>\n

\"\"<\/p>\n

\u603b\u7ed3\uff1a\u6cb3\u5357\u5e08\u8303\u5927\u5b66\u7684\u5e38\u4fca\u6807\u4e0e\u767d\u5927\u660c\u7b49\u4eba\u62a5\u9053\u4e00\u79cd\u5168\u65b0\u7684\u65e0\u91d1\u5c5e\u50ac\u5316bicyclo[1.1.0]butanes (BCBs)\u4e0e\u7f3a\u7535\u5b50\u70ef\u70c3\u7684\u6781\u6027\u53cd\u8f6cAlder-ene\u53cd\u5e94\u65b9\u6cd5\u5b66\uff0c\u8fdb\u800c\u6210\u529f\u5b8c\u6210\u4e00\u7cfb\u5217\u5b98\u80fd\u56e2\u5316\u7684\u73af\u4e01\u70ef\u4e0e\u5171\u8f6d\u4e8c\u70ef\u5206\u5b50\u7684\u6784\u5efa\u3002\u8fd9\u4e00\u5168\u65b0\u7684\u6781\u6027\u53cd\u8f6c\u5408\u6210\u8f6c\u5316\u7b56\u7565\u5177\u6709\u5e95\u7269\u8303\u56f4\u5e7f\u6cdb\u3001\u4f18\u826f\u7684\u5b98\u80fd\u56e2\u517c\u5bb9\u6027\u3001\u4f18\u826f\u7684\u539f\u5b50\u7ecf\u6d4e\u6027\u4ee5\u53ca\u4f18\u5f02\u7684\u9009\u62e9\u6027\u7b49\u4f18\u52bf\u3002<\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/h4>\n