{"id":51272,"date":"2024-09-19T08:35:58","date_gmt":"2024-09-19T00:35:58","guid":{"rendered":"\/\/www.gsbet888.com\/?p=51272"},"modified":"2024-09-19T08:41:35","modified_gmt":"2024-09-19T00:41:35","slug":"%e6%b8%af%e7%a7%91%e5%a4%a7%e9%92%b1%e5%9f%b9%e5%85%83-%e5%94%90%e6%9c%ac%e5%bf%a0-%e6%9c%b1%e5%b9%bf%e5%90%88%e4%bd%9ccej%ef%bc%9a-%e4%bb%8e%e6%b5%b7%e6%b4%8b%e7%bb%86%e8%8f%8c%e4%bb%a3%e8%b0%a2","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/%e5%8c%96%e5%ad%a6%e6%9d%82%e8%ae%b0\/recentpaper\/2024\/09\/%e6%b8%af%e7%a7%91%e5%a4%a7%e9%92%b1%e5%9f%b9%e5%85%83-%e5%94%90%e6%9c%ac%e5%bf%a0-%e6%9c%b1%e5%b9%bf%e5%90%88%e4%bd%9ccej%ef%bc%9a-%e4%bb%8e%e6%b5%b7%e6%b4%8b%e7%bb%86%e8%8f%8c%e4%bb%a3%e8%b0%a2.html","title":{"rendered":"\u6e2f\u79d1\u5927\u94b1\u57f9\u5143\/\u5510\u672c\u5fe0\/\u6731\u5e7f\u5408\u4f5cCEJ\uff1a \u4ece\u6d77\u6d0b\u7ec6\u83cc\u4ee3\u8c22\u4ea7\u7269\u4e2d\u9996\u6b21\u53d1\u73b0\u5177\u6709\u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\u6548\u5e94\u7684\u5206\u5b50"},"content":{"rendered":"

\u4f5c\u8005\uff1a\u77f3\u6cb9\u919a<\/strong><\/p>\n

\u5bfc\u8bfb<\/strong><\/h4>\n

\u8fd1\u65e5\uff0c\u9999\u6e2f\u79d1\u6280\u5927\u5b66\u94b1\u57f9\u5143\u3001\u5510\u672c\u5fe0\u548c\u6731\u5e7f\u6559\u6388\u7b49\u56e2\u961f\u5408\u4f5c\uff0c\u9996\u6b21\u4ece\u6d77\u6d0b\u7ec6\u83cc\u7684\u6b21\u7ea7\u4ee3\u8c22\u4ea7\u7269\u4e2d\u9274\u5b9a\u51fa\u5177\u6709AIE\u7279\u6027\u7684\u55b9\u5511\u916e\u7c7b\u751f\u7269\u78b1HMPQ\u3002\u8be5\u5206\u5b50\u5177\u6709\u6fc0\u53d1\u6001\u5206\u5b50\u5185\u8d28\u5b50\u8f6c\u79fb\uff08excited-state intramolecular proton transfer\uff0cESIPT\uff09\u7684\u7279\u6027\u3002\u6fc0\u53d1\u6001\u4e0b\uff0c\u7531\u4e8e\u5206\u5b50\u5185\u6c22\u952e\u7684\u4f5c\u7528\uff0cHMPQ\u4f1a\u7ecf\u5386\u201c\u70ef\u9187-\u916e\u201d\u7684\u53ef\u9006\u4e92\u53d8\u3002\u4e0d\u540c\u6781\u6027\u6eb6\u5242\u5bf9\u5206\u5b50\u5185\u6c22\u952e\u7684\u6291\u5236\u6548\u5e94\u5404\u5f02\uff0c\u4f7f\u5f97HMPQ\u5728\u4e0d\u540c\u6eb6\u5242\u4f53\u7cfb\u4e2d\u5448\u73b0\u51fa\u7531\u84dd\u5149\u5230\u7eff\u5149\u7684\u53ef\u63a7\u53d1\u5c04\u53d8\u5316\u3002\u901a\u8fc7XRD\u5355\u6676\u5206\u6790\u548cDFT\u8ba1\u7b97\uff0c\u4f5c\u8005\u63ed\u793a\u4e86\u5fae\u89c2\u5c42\u9762\u7684\u5206\u5b50\u5806\u79ef\u65b9\u5f0f\u548c\u6784\u8c61\u5dee\u5f02\u662f\u5bfc\u81f4\u5b8f\u89c2\u8367\u5149\u6027\u80fd\u5dee\u5f02\u7684\u6839\u672c\u539f\u56e0\u3002\u8fd9\u4e00\u6784\u6548\u5173\u7cfb\u7684\u7814\u7a76\u51f8\u663e\u4e86\u6676\u4f53\u5b66\u5728AIE\u6d3b\u6027\u5316\u5408\u7269\u8bbe\u8ba1\u4e0e\u5f00\u53d1\u4e2d\u7684\u5173\u952e\u4f5c\u7528\u3002<\/p>\n

\n

\u201cDiscovery of a novel marine bacterial AIEgen that lights up specific G-quadruplexes<\/p>\n

Wenkang Ye, Xinnan Wang, Parvej Alam, Changdong Liu , Monica C. Suen, Jianwei Tang, Herman H.Y. Sung , Ian D. Williams, Eric Y. Yu, Jacky W.Y. Lam, Guang Zhu*, Ben-Zhong Tang*, Pei-Yuan Qian*<\/p>\n

Chem. Eng. J, <\/em>2024<\/strong>, <\/em>497, 154947. Doi: 10.1016\/j.cej.2024.154947.<\/a>\u201d<\/p>\n<\/blockquote>\n

\"\"<\/p>\n

\u6458\u8981<\/strong><\/h4>\n

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u4e8c\u5341\u5e74\u524d\uff0c\u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\uff08Aggregation-induced emission, AIE\uff09\u73b0\u8c61\u7684\u53d1\u73b0\u6807\u5fd7\u7740\u5149\u7269\u7406\u53ca\u6750\u6599\u79d1\u5b66\u7684\u91cd\u5927\u8fdb\u6b65\u3002AIE\u6750\u6599\u5728\u56fa\u6001\u6216\u805a\u96c6\u6001\u4e0b\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u5149\u5b66\u6027\u8d28\uff0c\u514b\u670d\u4e86\u4f20\u7edf\u8367\u5149\u6750\u6599\u5728\u9ad8\u6d53\u5ea6\u6216\u805a\u96c6\u6001\u4e0b\u8367\u5149\u6dec\u706d\uff08Aggregation-caused quenching, ACQ\uff09\u7684\u5c40\u9650\u6027\uff0c\u4fc3\u8fdb\u4e86\u591a\u529f\u80fdAIE\u5206\u5b50\uff08AIEgens\uff09\u5728\u751f\u7269\u6210\u50cf\u3001\u5149\u7535\u548c\u751f\u5316\u4f20\u611f\u7b49\u9886\u57df\u7684\u53d1\u5c55\u3002\u7814\u7a76\u56e2\u961f\u9996\u6b21\u4ece\u6d77\u6d0b\u7ec6\u83cc\u4ee3\u8c22\u7269\u4e2d\u53d1\u73b0\u4e86\u5177\u6709AIE\u6027\u8d28\u7684\u65b0\u578b\u55b9\u5511\u916e\u751f\u7269\u78b1\u5c0f\u5206\u5b50\uff08HMPQ\uff09\u3002\u5149\u7269\u7406\u8868\u5f81\u7ed3\u679c\u663e\u793a\uff0cHMPQ\u5728\u4e0d\u540c\u6781\u6027\u6eb6\u5242\u548c\u56fa\u6001\u591a\u6676\u578b\u4e2d\u7684\u53d1\u5149\u8868\u73b0\u5404\u4e0d\u76f8\u540c\u3002\u6b64\u5916\uff0cHMPQ\u5bf9\u7279\u6b8a\u7684\u6838\u9178\u7ed3\u6784G-\u56db\u94fe\u4f53\uff08G4s\uff09\u8868\u73b0\u51fa\u7279\u5f02\u6027\u7ed3\u5408\u4eb2\u548c\u529b\uff0c\u80fd\u591f\u5728\u4e0d\u6539\u53d8\u5176\u6784\u8c61\u7684\u60c5\u51b5\u4e0b\u70b9\u4eae\u8fd9\u7c7b\u6838\u9178\u7ed3\u6784\u3002\u5176\u5353\u8d8a\u7684\u5b89\u5168\u6027\u548c\u5bf9\u7ec6\u80de\u4e2dG4s\u7ed3\u6784\u7684\u7cbe\u786e\u53ef\u89c6\u5316\u80fd\u529b\uff0c\u8868\u660eHMPQ\u5728\u751f\u7269\u5e94\u7528\u4e2d\u7684\u5de8\u5927\u6f5c\u529b\uff0c\u4e3a\u5f00\u53d1\u7528\u4f5c\u9ad8\u6548G4\u63a2\u9488\u7684\u65b0\u4e00\u4ee3BioAIEgens\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u3002<\/p>\n

\u80cc\u666f\u53ca\u5185\u5bb9<\/strong><\/h4>\n

\u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\uff08Aggregation-induced emission, AIE\uff09\u6750\u6599\u5728\u56fa\u6001\u6216\u805a\u96c6\u6001\u4e0b\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u5149\u5b66\u6027\u8d28\uff0c\u514b\u670d\u4e86\u4f20\u7edf\u8367\u5149\u6750\u6599\u5728\u9ad8\u6d53\u5ea6\u6216\u805a\u96c6\u6001\u4e0b\u8367\u5149\u6dec\u706d\u7684\u5c40\u9650\u6027\u3002\u8fd9\u4e00\u7279\u6027\u4f7fAIE\u6750\u6599\u5728\u751f\u7269\u6210\u50cf\u3001\u5149\u7535\u5b50\u5b66\u548c\u751f\u5316\u4f20\u611f\u7b49\u9886\u57df\u5177\u6709\u5e7f\u6cdb\u7684\u5e94\u7528\u524d\u666f\u3002\u4eceAIE\u6982\u5ff5\u7684\u63d0\u51fa\u81f3\u4eca\uff0c\u5168\u7403\u5df2\u6709145\u4e2a\u56fd\u5bb6\u6216\u5730\u533a\u3001\u7ea612,000\u4e2a\u7814\u7a76\u673a\u6784\u6216\u90e8\u95e8\u4ece\u4e8bAIE\u76f8\u5173\u9886\u57df\u7814\u7a76\uff0c\u603b\u5f15\u7528\u6b21\u6570\u8d85\u8fc730\u4e07\u6b21\uff0c\u8fd1\u4e24\u5e74\u6bcf\u5e74\u65b0\u589e\u7684SCI\u8bba\u6587\u8d85\u8fc71200\u7bc7\u3002<\/p>\n

\u7136\u800c\uff0c\u73b0\u6709\u7684AIE\u5206\u5b50\u4e3b\u8981\u57fa\u4e8e\u5408\u6210\u67d3\u6599\uff0c\u5176\u5408\u6210\u4e0e\u7eaf\u5316\u8fc7\u7a0b\u53ef\u80fd\u5e26\u6765\u73af\u5883\u6c61\u67d3\uff0c\u5e76\u5b58\u5728\u751f\u7269\u517c\u5bb9\u6027\u4e0d\u786e\u5b9a\u7684\u95ee\u9898\u3002\u6b64\u5916\uff0c\u5408\u6210\u65b9\u6cd5\u7684\u5c40\u9650\u6027\u4e5f\u9650\u5236\u4e86\u7ed3\u6784\u591a\u6837\u6027\u7684\u6269\u5c55\uff0c\u6210\u4e3a\u5176\u8fdb\u4e00\u6b65\u53d1\u5c55\u7684\u74f6\u9888\u3002\u56e0\u6b64\uff0c\u5f00\u53d1\u5929\u7136\u4ea7\u7269\u6765\u6e90\u7684\u751f\u7269AIE\u5206\u5b50\uff08BioAIEgens\uff09\u6210\u4e3a\u91cd\u8981\u7684\u7814\u7a76\u65b9\u5411\uff0c\u56e0\u5176\u5177\u5907\u53ef\u518d\u751f\u3001\u53ef\u751f\u7269\u964d\u89e3\u3001\u65e0\u6bd2\u6216\u4f4e\u6bd2\u6027\u3001\u4f18\u5f02\u7684\u751f\u7269\u76f8\u5bb9\u6027\u4ee5\u53ca\u591a\u6837\u7684\u836f\u7406\u6d3b\u6027\u3002<\/p>\n

\u76ee\u524d\uff0c\u5df2\u77e5\u7684\u751f\u7269AIE\u5206\u5b50\u4e3b\u8981\u6765\u6e90\u4e8e\u690d\u7269\uff0c\u5982\u59dc\u9ec4\u7d20\u3001\u69f2\u76ae\u7d20\u3001\u5c0f\u6a97\u78b1\u548c\u9999\u8c46\u7d20\u7b49\uff08\u56fe1\uff09\uff0c\u8fd9\u4e9b\u5206\u5b50\u5728\u751f\u7269\u76f8\u5bb9\u6027\u548c\u751f\u7269\u6d3b\u6027\u65b9\u9762\u8868\u73b0\u51fa\u8272\u3002\u7136\u800c\uff0c\u5fae\u751f\u7269\u6765\u6e90\u7684AIE\u5206\u5b50\u5c1a\u672a\u88ab\u5145\u5206\u63a2\u7d22\u3002\u4e0e\u690d\u7269\u76f8\u6bd4\uff0c\u7ec6\u83cc\u5177\u6709\u66f4\u77ed\u7684\u751f\u957f\u5468\u671f\uff0c\u57f9\u517b\u6761\u4ef6\u76f8\u5bf9\u7b80\u5355\u53ef\u63a7\uff0c\u66f4\u5bb9\u6613\u8fdb\u884c\u57fa\u56e0\u5de5\u7a0b\u6539\u9020\u4ee5\u63d0\u9ad8\u76ee\u6807\u4ea7\u7269\u7684\u4ea7\u91cf\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u6d77\u6d0b\u8986\u76d6\u4e86\u5730\u740370%\u4ee5\u4e0a\u7684\u8868\u9762\u79ef\uff0c\u5927\u91cf\u751f\u7269\u751f\u6d3b\u5728\u4e0e\u9646\u5730\u622a\u7136\u4e0d\u540c\u7684\u73af\u5883\u4e2d\u3002\u6d77\u6d0b\u72ec\u7279\u7684\u73af\u5883\u5b55\u80b2\u4e86\u4f17\u591a\u72ec\u7279\u7684\u5fae\u751f\u7269\u79cd\u7c7b\uff0c\u8fd9\u4e9b\u5fae\u751f\u7269\u9002\u5e94\u4e86\u6781\u7aef\u7684\u751f\u5b58\u6761\u4ef6\uff0c\u8fdb\u5316\u51fa\u591a\u6837\u7684\u4ee3\u8c22\u9014\u5f84\uff0c\u80fd\u591f\u751f\u4ea7\u51fa\u7ed3\u6784\u591a\u6837\u4e14\u5177\u6709\u751f\u7269\u6d3b\u6027\u7684\u5929\u7136\u4ea7\u7269\u3002\u56e0\u6b64\uff0c\u6d77\u6d0b\u5fae\u751f\u7269\u5929\u7136\u4ea7\u7269\u662f\u503c\u5f97\u6316\u6398\u7684AIE\u5206\u5b50\u5b9d\u5e93\u3002\"\"<\/p>\n

\u56fe<\/strong>1. <\/strong>\u5404\u7c7b\u5df2\u62a5\u9053\u7684\u690d\u7269\u6765\u6e90\u7684<\/strong>AIE<\/strong>\u5929\u7136\u4ea7\u7269\u53ca\u5176\u5728\u8367\u5149\u4f20\u611f\u548c\u751f\u7269\u6210\u50cf\u4e2d\u7684\u5e94\u7528<\/strong><\/p>\n

\u8fd1\u65e5\uff0c\u9999\u6e2f\u79d1\u6280\u5927\u5b66\u94b1\u57f9\u5143\u3001\u5510\u672c\u5fe0\u548c\u6731\u5e7f\u6559\u6388\u7b49\u56e2\u961f\u5408\u4f5c\uff0c\u9996\u6b21\u4ece\u6d77\u6d0b\u7ec6\u83cc\u7684\u6b21\u7ea7\u4ee3\u8c22\u4ea7\u7269\u4e2d\u9274\u5b9a\u51fa\u5177\u6709AIE\u7279\u6027\u7684\u55b9\u5511\u916e\u7c7b\u751f\u7269\u78b1HMPQ\u3002\u8be5\u5206\u5b50\u5177\u6709\u6fc0\u53d1\u6001\u5206\u5b50\u5185\u8d28\u5b50\u8f6c\u79fb\uff08excited-state intramolecular proton transfer\uff0cESIPT\uff09\u7684\u7279\u6027\u3002\u6fc0\u53d1\u6001\u4e0b\uff0c\u7531\u4e8e\u5206\u5b50\u5185\u6c22\u952e\u7684\u4f5c\u7528\uff0cHMPQ\u4f1a\u7ecf\u5386\u201c\u70ef\u9187-\u916e\u201d\u7684\u53ef\u9006\u4e92\u53d8\u3002\u4e0d\u540c\u6781\u6027\u6eb6\u5242\u5bf9\u5206\u5b50\u5185\u6c22\u952e\u7684\u6291\u5236\u6548\u5e94\u5404\u5f02\uff0c\u4f7f\u5f97HMPQ\u5728\u4e0d\u540c\u6eb6\u5242\u4f53\u7cfb\u4e2d\u5448\u73b0\u51fa\u7531\u84dd\u5149\u5230\u7eff\u5149\u7684\u53ef\u63a7\u53d1\u5c04\u53d8\u5316\uff08\u56fe3\uff09\u3002\u6b64\u5916\uff0cHMPQ\u5728\u540c\u4e00\u6eb6\u5242\u73af\u5883\u4e2d\u80fd\u591f\u5f62\u6210\u591a\u79cd\u6676\u5f62\uff0c\u5176\u4e2d\u9488\u72b6\u6676\u5f62\u5728\u6fc0\u53d1\u6001\u4e0b\u7684\u8367\u5149\u53d1\u5c04\u6548\u7387\u663e\u8457\u9ad8\u4e8e\u5757\u72b6\u6676\u4f53\uff08\u56fe5\uff09\u3002\u901a\u8fc7XRD\u5355\u6676\u5206\u6790\u548cDFT\u8ba1\u7b97\uff0c\u4f5c\u8005\u63ed\u793a\u4e86\u5fae\u89c2\u5c42\u9762\u7684\u5206\u5b50\u5806\u79ef\u65b9\u5f0f\u548c\u6784\u8c61\u5dee\u5f02\u662f\u5bfc\u81f4\u5b8f\u89c2\u8367\u5149\u6027\u80fd\u5dee\u5f02\u7684\u6839\u672c\u539f\u56e0\u3002\u8fd9\u4e00\u6784\u6548\u5173\u7cfb\u7684\u7814\u7a76\u51f8\u663e\u4e86\u6676\u4f53\u5b66\u5728AIE\u6d3b\u6027\u5316\u5408\u7269\u8bbe\u8ba1\u4e0e\u5f00\u53d1\u4e2d\u7684\u5173\u952e\u4f5c\u7528\u3002<\/p>\n

\"\"<\/p>\n

\u56fe<\/strong>2. <\/strong>\u5fae\u751f\u7269\u6765\u6e90\u7684<\/strong>AIE<\/strong>\u5c0f\u5206\u5b50<\/strong>HMPQ<\/strong>\u7684\u53d1\u73b0<\/strong><\/p>\n

\"\"<\/strong><\/p>\n

\u56fe<\/strong>3. HMPQ<\/strong>\u5728\u6eb6\u6db2\u6001\u7684\u5149\u7269\u7406\u8868\u5f81<\/strong><\/p>\n

\"\"<\/p>\n

\u56fe<\/strong>4. HMPQ<\/strong>\u5728\u805a\u96c6\u6001\u7684\u5149\u7269\u7406\u8868\u5f81<\/strong><\/p>\n

\"\"\u56fe<\/strong>5. HMPQ<\/strong>\u4e24\u79cd\u6676\u578b\u5c55\u73b0\u51fa\u622a\u7136\u4e0d\u540c\u7684\u53d1\u5149\u6027\u8d28<\/strong><\/p>\n

G-\u56db\u94fe\u4f53\uff08G4s\uff09\u5728\u4eba\u7c7b\u57fa\u56e0\u76f8\u5173\u7684\u751f\u7269\u8fc7\u7a0b\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\uff0c\u6210\u4e3a\u591a\u79cd\u4eba\u7c7b\u75be\u75c5\u8bca\u65ad\u4e0e\u6cbb\u7597\u7684\u6f5c\u5728\u9776\u70b9\u3002HMPQ\u5728\u4f53\u5916\u548c\u7ec6\u80de\u5185\u73af\u5883\u4e2d\u5747\u80fd\u5728\u4e0d\u6539\u53d8G4\u6784\u8c61\u7684\u60c5\u51b5\u4e0b\u7cbe\u51c6\u6807\u8bb0\u8fd9\u4e9b\u975e\u5178\u578b\u6838\u9178\u7ed3\u6784\uff0c\u5c55\u73b0\u51fa\u6781\u9ad8\u7684\u9009\u62e9\u6027\u548c\u7075\u654f\u5ea6\uff08\u56fe6\u4e0aa-d\uff09\u3002\u5171\u805a\u7126\u6210\u50cf\u7ed3\u679c\u8868\u660e\uff0cHMPQ\u901a\u8fc7\u7eff\u8272\u8367\u5149\u6210\u529f\u6807\u8bb0\u7ec6\u80de\u5185\u7684G-\u56db\u94fe\u4f53\u7ed3\u6784\uff0c\u5176\u4e0eG4s\u7684\u5546\u7528\u6297\u4f53\u6807\u8bb0\u7269BG4\u7684\u91cd\u5408\u7cfb\u6570\u9ad8\u8fbe94%\uff08\u56fe6\u4e0ba-e\uff09\u3002<\/p>\n

\"\"\"\"<\/p>\n

\u56fe<\/strong>6. HMPQ<\/strong>\u4e0e<\/strong>G<\/strong>\u56db\u94fe\u4f53\u53ef\u7279\u5f02\u6027\u7ed3\u5408\u5e76\u5728\u7ec6\u80de\u5185\u5916\u70b9\u4eae\u8be5\u7ed3\u6784<\/strong><\/p>\n

\u8be5\u7814\u7a76\u6210\u679c\u8fd1\u65e5\u4ee5Discovery of a novel marine bacterial AIEgen that lights up specific G-quadruplexes\u4e3a\u9898\u53d1\u8868\u5728Chemical Engineering Journal<\/em>\u4e0a\uff0c\u94b1\u57f9\u5143\u6559\u6388\uff0c\u5510\u672c\u5fe0\u9662\u58eb\u548c\u6731\u5e7f\u6559\u6388\u4e3a\u8be5\u8bba\u6587\u5171\u540c\u901a\u8baf\u4f5c\u8005\u3002\u9999\u6e2f\u79d1\u6280\u5927\u5b66\u53f6\u6587\u5eb7\u535a\u58eb\u548c\u738b\u6b23\u6960\u535a\u58eb\u4e3a\u8be5\u8bba\u6587\u5171\u540c\u7b2c\u4e00\u4f5c\u8005\u3002<\/p>\n

\uff08\u975e\u5e38\u611f\u8c22\u53f6\u6587\u5eb7\u535a\u58eb\u63d0\u4f9b\u7a3f\u4ef6<\/strong>\uff09<\/p>\n

\u8bf7\u767b\u9646TCI\u8bd5\u5242\u5b98\u7f51\u67e5\u770b\u66f4\u591a\u5185\u5bb9<\/h5>\n
https:\/\/www.tcichemicals.com\/CN\/zh\/<\/h5>\n

\n","protected":false},"excerpt":{"rendered":"\u4f5c\u8005\uff1a\u77f3\u6cb9\u919a \u5bfc\u8bfb \u8fd1\u65e5\uff0c\u9999\u6e2f\u79d1\u6280\u5927\u5b66\u94b1\u57f9\u5143\u3001\u5510\u672c\u5fe0\u548c\u6731\u5e7f\u6559\u6388\u7b49\u56e2\u961f\u5408\u4f5c\uff0c\u9996\u6b21\u4ece\u6d77\u6d0b\u7ec6\u83cc\u7684\u6b21\u7ea7\u4ee3\u8c22\u4ea7\u7269\u4e2d\u9274\u5b9a\u51fa\u5177\u6709AIE\u7279\u6027\u7684\u55b9\u5511\u916e\u7c7b\u751f\u7269\u78b1HMPQ\u3002\u8be5\u5206\u5b50\u5177\u6709\u6fc0\u53d1\u6001\u5206\u5b50\u5185\u8d28\u5b50\u8f6c\u79fb\uff08excited-state intramolecular proton transfer\uff0cESIPT\uff09\u7684\u7279\u6027\u3002\u6fc0\u53d1\u6001\u4e0b\uff0c\u7531\u4e8e\u5206\u5b50\u5185\u6c22\u952e\u7684\u4f5c\u7528\uff0cHMPQ\u4f1a\u7ecf\u5386\u201c\u70ef\u9187-\u916e\u201d\u7684\u53ef\u9006\u4e92\u53d8\u3002\u4e0d\u540c\u6781\u6027\u6eb6\u5242\u5bf9\u5206\u5b50\u5185\u6c22\u952e\u7684\u6291\u5236\u6548\u5e94\u5404\u5f02\uff0c\u4f7f\u5f97HMPQ\u5728\u4e0d\u540c\u6eb6\u5242\u4f53\u7cfb\u4e2d\u5448\u73b0\u51fa\u7531\u84dd\u5149\u5230\u7eff\u5149\u7684\u53ef\u63a7\u53d1\u5c04\u53d8\u5316\u3002\u901a\u8fc7XRD\u5355\u6676\u5206\u6790\u548cDFT\u8ba1\u7b97\uff0c\u4f5c\u8005\u63ed\u793a\u4e86\u5fae\u89c2\u5c42\u9762\u7684\u5206\u5b50\u5806\u79ef\u65b9\u5f0f\u548c\u6784\u8c61\u5dee\u5f02\u662f\u5bfc\u81f4\u5b8f\u89c2\u8367\u5149\u6027\u80fd\u5dee\u5f02\u7684\u6839\u672c\u539f\u56e0\u3002\u8fd9\u4e00\u6784\u6548\u5173\u7cfb\u7684\u7814\u7a76\u51f8\u663e\u4e86\u6676\u4f53\u5b66\u5728AIE\u6d3b\u6027\u5316\u5408\u7269\u8bbe\u8ba1\u4e0e\u5f00\u53d1\u4e2d\u7684\u5173\u952e\u4f5c\u7528\u3002 \u201cDiscovery of a novel marine bacterial AIEgen that lights up specific G-quadruplexes Wenkang Ye, Xinnan Wang, Parvej Alam, Changdong Liu , Monica C. Suen, Jianwei Tang, Herman H.Y. Sung , Ian D. Williams, Eric Y. Yu, Jacky W.Y. Lam, Guang Zhu*, Ben-Zhong Tang*, Pei-Yuan Qian* Chem. Eng. J, 2024, 497, 154947. Doi: 10.1016\/j.cej.2024.154947.\u201d \u6458\u8981 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u4e8c\u5341\u5e74\u524d\uff0c\u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\uff08Aggregation-induced emission, AIE\uff09\u73b0\u8c61\u7684\u53d1\u73b0\u6807\u5fd7\u7740\u5149\u7269\u7406\u53ca\u6750\u6599\u79d1\u5b66\u7684\u91cd\u5927\u8fdb\u6b65\u3002AIE\u6750\u6599\u5728\u56fa\u6001\u6216\u805a\u96c6\u6001\u4e0b\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u5149\u5b66\u6027\u8d28\uff0c\u514b\u670d\u4e86\u4f20\u7edf\u8367\u5149\u6750\u6599\u5728\u9ad8\u6d53\u5ea6\u6216\u805a\u96c6\u6001\u4e0b\u8367\u5149\u6dec\u706d\uff08Aggregation-caused quenching, ACQ\uff09\u7684\u5c40\u9650\u6027\uff0c\u4fc3\u8fdb\u4e86\u591a\u529f\u80fdAIE\u5206\u5b50\uff08AIEgens\uff09\u5728\u751f\u7269\u6210\u50cf\u3001\u5149\u7535\u548c\u751f\u5316\u4f20\u611f\u7b49\u9886\u57df\u7684\u53d1\u5c55\u3002\u7814\u7a76\u56e2\u961f\u9996\u6b21\u4ece\u6d77\u6d0b\u7ec6\u83cc\u4ee3\u8c22\u7269\u4e2d\u53d1\u73b0\u4e86\u5177\u6709AIE\u6027\u8d28\u7684\u65b0\u578b\u55b9\u5511\u916e\u751f\u7269\u78b1\u5c0f\u5206\u5b50\uff08HMPQ\uff09\u3002\u5149\u7269\u7406\u8868\u5f81\u7ed3\u679c\u663e\u793a\uff0cHMPQ\u5728\u4e0d\u540c\u6781\u6027\u6eb6\u5242\u548c\u56fa\u6001\u591a\u6676\u578b\u4e2d\u7684\u53d1\u5149\u8868\u73b0\u5404\u4e0d\u76f8\u540c\u3002\u6b64\u5916\uff0cHMPQ\u5bf9\u7279\u6b8a\u7684\u6838\u9178\u7ed3\u6784G-\u56db\u94fe\u4f53\uff08G4s\uff09\u8868\u73b0\u51fa\u7279\u5f02\u6027\u7ed3\u5408\u4eb2\u548c\u529b\uff0c\u80fd\u591f\u5728\u4e0d\u6539\u53d8\u5176\u6784\u8c61\u7684\u60c5\u51b5\u4e0b\u70b9\u4eae\u8fd9\u7c7b\u6838\u9178\u7ed3\u6784\u3002\u5176\u5353\u8d8a\u7684\u5b89\u5168\u6027\u548c\u5bf9\u7ec6\u80de\u4e2dG4s\u7ed3\u6784\u7684\u7cbe\u786e\u53ef\u89c6\u5316\u80fd\u529b\uff0c\u8868\u660eHMPQ\u5728\u751f\u7269\u5e94\u7528\u4e2d\u7684\u5de8\u5927\u6f5c\u529b\uff0c\u4e3a\u5f00\u53d1\u7528\u4f5c\u9ad8\u6548G4\u63a2\u9488\u7684\u65b0\u4e00\u4ee3BioAIEgens\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u3002 \u80cc\u666f\u53ca\u5185\u5bb9 \u805a\u96c6\u8bf1\u5bfc\u53d1\u5149\uff08Aggregation-induced emission, AIE\uff09\u6750\u6599\u5728\u56fa\u6001\u6216\u805a\u96c6\u6001\u4e0b\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u5149\u5b66\u6027\u8d28\uff0c\u514b\u670d\u4e86\u4f20\u7edf\u8367\u5149\u6750\u6599\u5728\u9ad8\u6d53\u5ea6\u6216\u805a\u96c6\u6001\u4e0b\u8367\u5149\u6dec\u706d\u7684\u5c40\u9650\u6027\u3002\u8fd9\u4e00\u7279\u6027\u4f7fAIE\u6750\u6599\u5728\u751f\u7269\u6210\u50cf\u3001\u5149\u7535\u5b50\u5b66\u548c\u751f\u5316\u4f20\u611f\u7b49\u9886\u57df\u5177\u6709\u5e7f\u6cdb\u7684\u5e94\u7528\u524d\u666f\u3002\u4eceAIE\u6982\u5ff5\u7684\u63d0\u51fa\u81f3\u4eca\uff0c\u5168\u7403\u5df2\u6709145\u4e2a\u56fd\u5bb6\u6216\u5730\u533a\u3001\u7ea612,000\u4e2a\u7814\u7a76\u673a\u6784\u6216\u90e8\u95e8\u4ece\u4e8bAIE\u76f8\u5173\u9886\u57df\u7814\u7a76\uff0c\u603b\u5f15\u7528\u6b21\u6570\u8d85\u8fc730\u4e07\u6b21\uff0c\u8fd1\u4e24\u5e74\u6bcf\u5e74\u65b0\u589e\u7684SCI\u8bba\u6587\u8d85\u8fc71200\u7bc7\u3002 \u7136\u800c\uff0c\u73b0\u6709\u7684AIE\u5206\u5b50\u4e3b\u8981\u57fa\u4e8e\u5408\u6210\u67d3\u6599\uff0c\u5176\u5408\u6210\u4e0e\u7eaf\u5316\u8fc7\u7a0b\u53ef\u80fd\u5e26\u6765\u73af\u5883\u6c61\u67d3\uff0c\u5e76\u5b58\u5728\u751f\u7269\u517c\u5bb9\u6027\u4e0d\u786e\u5b9a\u7684\u95ee\u9898\u3002\u6b64\u5916\uff0c\u5408\u6210\u65b9\u6cd5\u7684\u5c40\u9650\u6027\u4e5f\u9650\u5236\u4e86\u7ed3\u6784\u591a\u6837\u6027\u7684\u6269\u5c55\uff0c\u6210\u4e3a\u5176\u8fdb\u4e00\u6b65\u53d1\u5c55\u7684\u74f6\u9888\u3002\u56e0\u6b64\uff0c\u5f00\u53d1\u5929\u7136\u4ea7\u7269\u6765\u6e90\u7684\u751f\u7269AIE\u5206\u5b50\uff08BioAIEgens\uff09\u6210\u4e3a\u91cd\u8981\u7684\u7814\u7a76\u65b9\u5411\uff0c\u56e0\u5176\u5177\u5907\u53ef\u518d\u751f\u3001\u53ef\u751f\u7269\u964d\u89e3\u3001\u65e0\u6bd2\u6216\u4f4e\u6bd2\u6027\u3001\u4f18\u5f02\u7684\u751f\u7269\u76f8\u5bb9\u6027\u4ee5\u53ca\u591a\u6837\u7684\u836f\u7406\u6d3b\u6027\u3002 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