Chem-Station<\/em><\/strong> \u673a\u7406<\/strong>(<\/strong>\u4e03<\/strong>)<\/strong><\/h4>\n\u4e3a\u4e0b\u9762\u7684\u53cd\u5e94\u63d0\u51fa\u4e00\u79cd\u5408\u7406\u7684\u53cd\u5e94\u673a\u7406\u3002
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\u8bf7\u6ce8\u610f\u6bcf\u6b65\u4e2d\u4ea7\u7269\u7684\u7acb\u4f53\u6784\u578b\uff0c\u540c\u65f6\u6ce8\u610f\u63d0\u51fa\u7684\u53cd\u5e94\u673a\u7406\u5fc5\u987b\u80fd\u591f\u89e3\u91ca\u6bcf\u6b65\u4e2d\u4ea7\u7269\u7684\u7acb\u4f53\u9009\u62e9\u6027\u3002<\/p>\n
Chem-Station<\/em><\/strong> \u673a\u7406<\/strong>(<\/strong>\u4e03<\/strong>)<\/strong>\u7684\u53c2\u8003\u7b54\u6848<\/strong><\/h4>\n <\/p>\n
<\/strong><\/p>\n\u8bc4\u5206\u6807\u51c6\uff1a<\/strong><\/h4>\n(1) \u53cd\u5e94\u673a\u7406\u5408\u7406\uff0c\u5173\u952e\u4e2d\u95f4\u4f53\u6b63\u786e\uff0c\u7b26\u5408\u6709\u673a\u5316\u5b66\u7684\u76f8\u5173\u673a\u7406\u53ca\u7ed3\u6784\u7406\u8bba\uff0c\u65e0\u660e\u663e\u7684\u7406\u8bba\u77e5\u8bc6\u9519\u8bef\u4ee5\u53ca\u65e0\u4ea7\u7269\u6784\u578b\u6807\u6ce8\u9519\u8bef (75-80\u5206)\u3002<\/p>\n
(2) \u53cd\u5e94\u673a\u7406\u7bad\u5934\u6807\u6ce8\u89c4\u8303\u5168\u9762\uff0c\u7535\u5b50\u8f6c\u79fb\u4f4d\u7f6e\u6e05\u6670\u660e\u786e\uff0c\u7535\u5b50\u8f6c\u79fb\u65b9\u5411\u51c6\u786e\u65e0\u8bef (10-15\u5206)\u3002<\/p>\n
(3) \u5728\u7b26\u5408\u4e0a\u8ff0\u4e24\u70b9\u7684\u57fa\u7840\u4e0a\uff0c\u56fe\u7247\u7f8e\u89c2\uff0c\u80fd\u591f\u660e\u663e\u5438\u5f15\u8bfb\u8005\u9605\u8bfb (5-10\u5206)\u3002<\/p>\n<\/div>\n
\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/h4>\n\n[1] A. Rehpenn, S. Hindelang, K. Truong, A. P\u00f6thig, G. Storch, Angew. Chem. Int. Ed.<\/em> 2024<\/strong>, 63<\/em>, e202318590. doi: 10.1002\/anie.202318590<\/a>.<\/p>\n4\u03c0-photocyclization:<\/p>\n
(1) C. Guerra, Y. A. Rodr\u00edguez-N\u00fa\u00f1ez, M. E. Taborda-Mart\u00ednez, M. Bacho, R. Miranda-Pastrana, A. E. Ensunchoc, New J. Chem.<\/em><\/strong> 2024, 48<\/em>, <\/strong>17633. doi: 10.1039\/D4NJ03442B<\/a>.<\/p>\n(2) S. C. Coote, Eur. J. Org. Chem. <\/em>2020, <\/strong>1405. doi: 10.1002\/ejoc.201901230<\/a>.<\/p>\n(3) A. C. Day, M. A. Ledlie, J. Chem. Soc. D<\/em><\/strong> 1970<\/strong>, 1265b. doi: 10.1039\/C2970001265B<\/a>.<\/p>\ndivinylcyclopropane rearrangement:<\/p>\n
(1) S. Kr\u00fcger, T. Gaich, Beilstein J. Org. Chem.<\/em> 2014<\/strong>, 10<\/em>, 163. doi:\u00a010.3762\/bjoc.10.14<\/a>.<\/p>\nother flavin acted as a triplet sensitizer:<\/p>\n
(1) H. Li, M.-T. Zhang, J. Photochem. Photobiol. A <\/em>2018<\/strong>, 355<\/em>, 109. doi: 10.1016\/j.jphotochem.2017.09.077.<\/a><\/p>\n(2) W. Zhang, K. L. Carpenter, S. Lin, Angew. Chem. Int. Ed. <\/em>2020<\/strong>, 59<\/em>, 409. doi: 10.1002\/anie.201910300<\/a>.<\/p>\n(3) J. B. Metternich, R. Gilmour, J. Am. Chem. Soc. <\/em>2015<\/strong>, 137<\/em>, 11254. doi: 10.1021\/jacs.5b07136<\/a>.<\/p>\n(4) M. P. Kabir, P. Ghosh, S. Gozem, J. Phys. Chem. B<\/em>\u00a02024<\/strong>, 128<\/em>, 31, 7545. doi: 10.1021\/acs.jpcb.4c03748<\/a>.<\/p>\n(5) A. Rehpenn, A. Waltera, G. Storch, Chem. Sci.<\/em><\/strong> 2022<\/strong>, 13<\/em><\/strong>,<\/strong> 14151. doi: 10.1039\/D2SC04341F<\/a>.<\/p>\n(6) C. T. Walsh, T. A. Wencewicz, Nat. Prod. Rep.<\/em><\/strong> 2013<\/strong>, 30<\/em><\/strong>, 175. doi:\u00a010.1039\/C2NP20069D<\/a>.<\/p>\n(7) A. Walter, W. Eisenreich, and G. Storch, Angew. Chem. Int. Ed.<\/em>\u00a02023, <\/strong>62<\/em>, 42, e202310634. doi:\u00a010.1002\/anie.202310634<\/a>.<\/p>\n(8) T. Langschwager, G. Storch. Angew. Chem. Int. Ed.<\/em> 2024<\/strong>, 63<\/em>, e20241467. doi: 10.1002\/anie.202414679<\/a>.<\/p>\n(9) R. Foja, A. Walter, C. Jandl, E. Thyrhaug, J. Hauer, G. Storch. J. Am. Chem. Soc.<\/em>\u00a02022<\/strong>, 144<\/em>, 4721. doi:10.1021\/jacs.1c13285<\/a>.<\/p>\n(10) J. B. Metternich, R. Gilmour, J. Am. Chem. Soc. <\/em>2016<\/strong>, 138<\/em>, 1040. doi: 10.1021\/jacs.5b12081<\/a>.<\/p>\n

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(1) \u53cd\u5e94\u673a\u7406\u5408\u7406\uff0c\u5173\u952e\u4e2d\u95f4\u4f53\u6b63\u786e\uff0c\u7b26\u5408\u6709\u673a\u5316\u5b66\u7684\u76f8\u5173\u673a\u7406\u53ca\u7ed3\u6784\u7406\u8bba\uff0c\u65e0\u660e\u663e\u7684\u7406\u8bba\u77e5\u8bc6\u9519\u8bef\u4ee5\u53ca\u65e0\u4ea7\u7269\u6784\u578b\u6807\u6ce8\u9519\u8bef (75-80\u5206)\u3002<\/p>\n (2) \u53cd\u5e94\u673a\u7406\u7bad\u5934\u6807\u6ce8\u89c4\u8303\u5168\u9762\uff0c\u7535\u5b50\u8f6c\u79fb\u4f4d\u7f6e\u6e05\u6670\u660e\u786e\uff0c\u7535\u5b50\u8f6c\u79fb\u65b9\u5411\u51c6\u786e\u65e0\u8bef (10-15\u5206)\u3002<\/p>\n (3) \u5728\u7b26\u5408\u4e0a\u8ff0\u4e24\u70b9\u7684\u57fa\u7840\u4e0a\uff0c\u56fe\u7247\u7f8e\u89c2\uff0c\u80fd\u591f\u660e\u663e\u5438\u5f15\u8bfb\u8005\u9605\u8bfb (5-10\u5206)\u3002<\/p>\n<\/div>\n 4\u03c0-photocyclization:<\/p>\n (1) C. Guerra, Y. A. Rodr\u00edguez-N\u00fa\u00f1ez, M. E. Taborda-Mart\u00ednez, M. Bacho, R. Miranda-Pastrana, A. E. Ensunchoc, New J. Chem.<\/em><\/strong> 2024, 48<\/em>, <\/strong>17633. doi: 10.1039\/D4NJ03442B<\/a>.<\/p>\n (2) S. C. Coote, Eur. J. Org. Chem. <\/em>2020, <\/strong>1405. doi: 10.1002\/ejoc.201901230<\/a>.<\/p>\n (3) A. C. Day, M. A. Ledlie, J. Chem. Soc. D<\/em><\/strong> 1970<\/strong>, 1265b. doi: 10.1039\/C2970001265B<\/a>.<\/p>\n divinylcyclopropane rearrangement:<\/p>\n (1) S. Kr\u00fcger, T. Gaich, Beilstein J. Org. Chem.<\/em> 2014<\/strong>, 10<\/em>, 163. doi:\u00a010.3762\/bjoc.10.14<\/a>.<\/p>\n other flavin acted as a triplet sensitizer:<\/p>\n (1) H. Li, M.-T. Zhang, J. Photochem. Photobiol. A <\/em>2018<\/strong>, 355<\/em>, 109. doi: 10.1016\/j.jphotochem.2017.09.077.<\/a><\/p>\n (2) W. Zhang, K. L. Carpenter, S. Lin, Angew. Chem. Int. Ed. <\/em>2020<\/strong>, 59<\/em>, 409. doi: 10.1002\/anie.201910300<\/a>.<\/p>\n (3) J. B. Metternich, R. Gilmour, J. Am. Chem. Soc. <\/em>2015<\/strong>, 137<\/em>, 11254. doi: 10.1021\/jacs.5b07136<\/a>.<\/p>\n (4) M. P. Kabir, P. Ghosh, S. Gozem, J. Phys. Chem. B<\/em>\u00a02024<\/strong>, 128<\/em>, 31, 7545. doi: 10.1021\/acs.jpcb.4c03748<\/a>.<\/p>\n (5) A. Rehpenn, A. Waltera, G. Storch, Chem. Sci.<\/em><\/strong> 2022<\/strong>, 13<\/em><\/strong>,<\/strong> 14151. doi: 10.1039\/D2SC04341F<\/a>.<\/p>\n (6) C. T. Walsh, T. A. Wencewicz, Nat. Prod. Rep.<\/em><\/strong> 2013<\/strong>, 30<\/em><\/strong>, 175. doi:\u00a010.1039\/C2NP20069D<\/a>.<\/p>\n (7) A. Walter, W. Eisenreich, and G. Storch, Angew. Chem. Int. Ed.<\/em>\u00a02023, <\/strong>62<\/em>, 42, e202310634. doi:\u00a010.1002\/anie.202310634<\/a>.<\/p>\n (8) T. Langschwager, G. Storch. Angew. Chem. Int. Ed.<\/em> 2024<\/strong>, 63<\/em>, e20241467. doi: 10.1002\/anie.202414679<\/a>.<\/p>\n (9) R. Foja, A. Walter, C. Jandl, E. Thyrhaug, J. Hauer, G. Storch. J. Am. Chem. Soc.<\/em>\u00a02022<\/strong>, 144<\/em>, 4721. doi:10.1021\/jacs.1c13285<\/a>.<\/p>\n (10) J. B. Metternich, R. Gilmour, J. Am. Chem. Soc. <\/em>2016<\/strong>, 138<\/em>, 1040. doi: 10.1021\/jacs.5b12081<\/a>.<\/p>\n<\/strong><\/p>\n
\u8bc4\u5206\u6807\u51c6\uff1a<\/strong><\/h4>\n
\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/h4>\n