{"id":9465,"date":"2016-04-29T13:21:52","date_gmt":"2016-04-29T05:21:52","guid":{"rendered":"\/\/www.gsbet888.com\/?p=9465"},"modified":"2019-08-02T18:54:29","modified_gmt":"2019-08-02T10:54:29","slug":"post-9465","status":"publish","type":"post","link":"\/\/www.gsbet888.com\/chemists\/2016\/04\/post-9465.html","title":{"rendered":"Matthew\u30fbB\u30fbFrancis"},"content":{"rendered":"<p>Matthew\u30fbB\u30fbFrancis\uff081971\u5e74xx\u6708xx\u65e5, \u751f\u4e8e\u7f8e\u56fdOhio\u5dde\uff0c\u662f\u7f8e\u56fd\u5316\u5b66\u5bb6\u3002\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u6559\u6388\u3002(\u5199\u771f\u6765\u81ea\uff1aUC Berkeley HP)<\/p>\n<p>&nbsp;<\/p>\n<h4>\u7ecf\u5386<\/h4>\n<p>1994 \u8fc8\u963f\u5bc6\u5927\u5b66 \u6bd5\u4e1a<br \/>\n1994-1999 \u54c8\u4f5b\u5927\u5b66\u5316\u5b66\u79d1 \u535a\u58eb\u5b66\u4f4d (<a href=\"http:\/\/www.chem-station.com\/chemist-db\/archives\/2008\/09\/-eric-n-jacobsen.php\">Eric Jacobsen<\/a>\u6559\u6388)<br \/>\n1999-2001\u3000\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821Miller Institute for Basic Research in Science \u535a\u58eb\u7814\u7a76\u5458\uff08<a href=\"http:\/\/www.chem-station.com\/chemist-db\/archives\/2009\/08\/-jean-m-j-frechet.php\">Jean Fr\u00e9chet<\/a>\u6559\u6388\uff09<br \/>\n2001- \u00a0 \u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821<br \/>\n\u73b0\u5728 The T.Z. and Irmgard Chu Distinguished Professor in Chemistry<\/p>\n<p>&nbsp;<\/p>\n<h4>\u83b7\u5956\u7ecf\u5386<\/h4>\n<p>2001 Camille and Henry Dreyfus Foundation New Faculty Award<br \/>\n200x NSF Career Award<br \/>\n200x GlaxoSmithKline Young Investigator Award<br \/>\n200x Noyce Prize for Excellence in Undergraduate Teaching<br \/>\n2009 University Distinguished Teaching Award<\/p>\n<p>&nbsp;<\/p>\n<h4>\u7814\u7a76\u4e1a\u7ee9<\/h4>\n<p><strong>\u65b0\u578b\u86cb\u767d\u8d28\u751f\u7269\u7ed3\u5408\u53cd\u5e94\u7684\u5f00\u53d1\u53ca\u5176\u5728\u673a\u80fd\u6027\u6750\u6599\u4e2d\u7684\u5e94\u7528<\/strong><\/p>\n<p>\u5229\u7528\u80fd\u88ab\u6c27\u5316\u800c\u6d3b\u5316\u7684\u8bd5\u5242\u53ca\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u5242\uff0c\u5f00\u53d1\u65b0\u578b\u53cd\u5e94\u80fd\u591f\u5728\u86cb\u767d\u8d28\u7684\u591a\u4e2a\u4f4d\u7f6e\u8fdb\u884c\u9009\u62e9\u6027\u4fee\u9970\u3002\u4ed6\u662f\u8fd9\u4e00\u9886\u57df\u4e2d\u5f00\u62d3\u5148\u9a71\u7684\u5316\u5b66\u5bb6\u4e4b\u4e00\u3002[1-3]\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/MB_Francis_3.gif\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-9617\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/MB_Francis_3.gif\" alt=\"MB_Francis_3\" width=\"500\" height=\"188\" \/><\/a><\/p>\n<p>\u540c\u65f6\u4ed6\u8fd8\u5f00\u53d1\u5229\u7528\u8fd9\u4e9b\u65b0\u578b\u5408\u6210\u53cd\u5e94\u800c\u4eba\u5de5\u5408\u6210\u7684\u86cb\u767d\u8d28\uff0c\u7528\u4e8e\u673a\u80fd\u6027\u6750\u6599[4]\u3002<\/p>\n<p>\u4f8b\u5982\u4e0b\u9762\u56fe\u4e2d\uff0c\u901a\u8fc7\u5bf9\u75c5\u6bd2\u8863\u58f3\u86cb\u767d\u8fdb\u884c\u4eba\u5de5\u5316\u5b66\u4fee\u9970\u5f97\u5230\u4e86\u65b0\u578bcore\/shell\u6750\u6599\u3002<\/p>\n<p><a href=\"https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/MB_Francis_1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-9618\" src=\"https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/MB_Francis_1.png\" alt=\"MB_Francis_1\" width=\"890\" height=\"432\" srcset=\"https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/MB_Francis_1.png 890w, https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/MB_Francis_1-300x146.png 300w, https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/MB_Francis_1-768x373.png 768w, https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/MB_Francis_1-680x330.png 680w\" sizes=\"(max-width: 890px) 100vw, 890px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<h4>\u76f8\u5173\u6587\u732e<\/h4>\n<ol>\n<li>\u201cChoosing an effective protein bioconjugation strategy\u201d Stephanopoulos,N.; Francis, M. B.\u00a0<em>Nat. Chem. Biol.<\/em><strong>\u00a02011<\/strong>,\u00a0<em>7<\/em>, 876. doi:<a href=\"http:\/\/dx.doi.org\/10.1038\/nchembio.720\">10.1038\/nchembio.720<\/a><\/li>\n<li>\u201cDevelopment of Oxidative Coupling Strategies for Site-Selective Protein Modification\u201d ElSohly, A. M.; Francis, M. B.\u00a0<em>Acc. Chem. Res.<\/em>\u00a0<strong>2015<\/strong>,\u00a0<em>48<\/em>, 1971. DOI:<a href=\"http:\/\/dx.doi.org\/%2010.1021\/acs.accounts.5b00139\">\u00a010.1021\/acs.accounts.5b00139<\/a><\/li>\n<li>\u201cOne-step site-specific modification of native proteins with 2-pyridinecarboxyaldehydes\u201d MacDonald, J. I.; Munch,H. K.; Moore, T.; Francis, M. B.\u00a0<em>Nat. Chem.Biol.<\/em>\u00a0<strong>2015<\/strong>,\u00a0<em>11<\/em>, 326. doi:<a href=\"http:\/\/dx.doi.org\/10.1038\/nchembio.1792\">10.1038\/nchembio.1792<\/a><\/li>\n<li>\u201cUsing Synthetically Modified Proteins to Make New Materials\u201d Witus, L. S.; Francis, M. B.\u00a0<em>Acc. Chem. Res.<\/em>\u00a0<strong>2011<\/strong>,\u00a0<em>44<\/em>, 774. DOI:\u00a0<a href=\"http:\/\/dx.doi.org\/10.1021\/ar2001292\">10.1021\/ar2001292<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<h4>\u76f8\u5173\u52a8\u753b<\/h4>\n<div class=\"embed-vimeo\" style=\"text-align: center;\"><iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/92264445\" width=\"500\" height=\"281\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe><\/div>\n<p>&nbsp;<\/p>\n<h4>\u76f8\u5173\u4e66\u7c4d<\/h4>\n[amazonjs asin=&#8221;0123822394&#8243; locale=&#8221;CN&#8221; title=&#8221;Bioconjugate Techniques, Third Edition&#8221;]\n[amazonjs asin=&#8221;1617791504&#8243; locale=&#8221;CN&#8221; title=&#8221;Bioconjugation Protocols: Strategies and Methods&#8221;]\n<p>&nbsp;<\/p>\n<h4>\u76f8\u5173\u94fe\u63a5<\/h4>\n<ul>\n<li><a href=\"http:\/\/mbfgrp.cchem.berkeley.edu\/\">Francis Research Group<\/a><\/li>\n<\/ul>\n<div id=\"wp_rp_first\" class=\"wp_rp_wrap wp_rp_modern\"><\/div>\n","protected":false},"excerpt":{"rendered":"Matthew\u30fbB\u30fbFrancis\uff081971\u5e74xx\u6708xx\u65e5, \u751f\u4e8e\u7f8e\u56fdOhio\u5dde\uff0c\u662f\u7f8e\u56fd\u5316\u5b66\u5bb6\u3002\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u6559\u6388\u3002(\u5199\u771f\u6765\u81ea\uff1aUC Berkeley HP) &nbsp; \u7ecf\u5386 1994 \u8fc8\u963f\u5bc6\u5927\u5b66 \u6bd5\u4e1a 1994-1999 \u54c8\u4f5b\u5927\u5b66\u5316\u5b66\u79d1 \u535a\u58eb\u5b66\u4f4d (Eric Jacobsen\u6559\u6388) 1999-2001\u3000\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821Miller Institute for Basic Research in Science \u535a\u58eb\u7814\u7a76\u5458\uff08Jean Fr\u00e9chet\u6559\u6388\uff09 2001- \u00a0 \u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821 \u73b0\u5728 The T.Z. and Irmgard Chu Distinguished Professor in Chemistry &nbsp; \u83b7\u5956\u7ecf\u5386 2001 Camille and Henry Dreyfus Foundation New Faculty Award 200x NSF Career Award 200x GlaxoSmithKline Young Investigator Award 200x Noyce Prize for Excellence in Undergraduate Teaching 2009 University Distinguished Teaching Award &nbsp; \u7814\u7a76\u4e1a\u7ee9 \u65b0\u578b\u86cb\u767d\u8d28\u751f\u7269\u7ed3\u5408\u53cd\u5e94\u7684\u5f00\u53d1\u53ca\u5176\u5728\u673a\u80fd\u6027\u6750\u6599\u4e2d\u7684\u5e94\u7528 \u5229\u7528\u80fd\u88ab\u6c27\u5316\u800c\u6d3b\u5316\u7684\u8bd5\u5242\u53ca\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u5242\uff0c\u5f00\u53d1\u65b0\u578b\u53cd\u5e94\u80fd\u591f\u5728\u86cb\u767d\u8d28\u7684\u591a\u4e2a\u4f4d\u7f6e\u8fdb\u884c\u9009\u62e9\u6027\u4fee\u9970\u3002\u4ed6\u662f\u8fd9\u4e00\u9886\u57df\u4e2d\u5f00\u62d3\u5148\u9a71\u7684\u5316\u5b66\u5bb6\u4e4b\u4e00\u3002[1-3] \u540c\u65f6\u4ed6\u8fd8\u5f00\u53d1\u5229\u7528\u8fd9\u4e9b\u65b0\u578b\u5408\u6210\u53cd\u5e94\u800c\u4eba\u5de5\u5408\u6210\u7684\u86cb\u767d\u8d28\uff0c\u7528\u4e8e\u673a\u80fd\u6027\u6750\u6599[4]\u3002 \u4f8b\u5982\u4e0b\u9762\u56fe\u4e2d\uff0c\u901a\u8fc7\u5bf9\u75c5\u6bd2\u8863\u58f3\u86cb\u767d\u8fdb\u884c\u4eba\u5de5\u5316\u5b66\u4fee\u9970\u5f97\u5230\u4e86\u65b0\u578bcore\/shell\u6750\u6599\u3002 &nbsp; \u76f8\u5173\u6587\u732e \u201cChoosing an effective protein bioconjugation strategy\u201d Stephanopoulos,N.; Francis, M. B.\u00a0Nat. Chem. Biol.\u00a02011,\u00a07, 876. doi:10.1038\/nchembio.720 \u201cDevelopment of Oxidative Coupling Strategies for Site-Selective Protein Modification\u201d ElSohly, A. M.; Francis, M. B.\u00a0Acc. Chem. Res.\u00a02015,\u00a048, 1971. DOI:\u00a010.1021\/acs.accounts.5b00139 [&hellip;]","protected":false},"author":3,"featured_media":9621,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[212],"tags":[1317,1316,216],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/assets.www.gsbet888.com\/uploads\/2016\/04\/123.jpg","jetpack_shortlink":"https:\/\/wp.me\/p96op1-2sF","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/9465"}],"collection":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/comments?post=9465"}],"version-history":[{"count":2,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/9465\/revisions"}],"predecessor-version":[{"id":27707,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/posts\/9465\/revisions\/27707"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media\/9621"}],"wp:attachment":[{"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/media?parent=9465"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/categories?post=9465"},{"taxonomy":"post_tag","embeddable":true,"href":"\/\/www.gsbet888.com\/wp-json\/wp\/v2\/tags?post=9465"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}